Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.08	0.222	0.524	13.0	-0.661	14.0	27.0
IHH	0.024	0.184	0.369	14.0	-0.876	8.0	22.0
SHH Np/Cholesterol/GAS1	-0.108	0.239	-9999.0	0.0	-0.595	49.0	49.0
LRPAP1	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.107	0.236	0.589	49.0	-9999.0	0.0	49.0
SMO/beta Arrestin2	0.006	0.206	0.339	1.0	-0.736	15.0	16.0
SMO	0.007	0.221	0.379	1.0	-0.786	15.0	16.0
AKT1	0.015	0.135	-9999.0	0.0	-1.597	1.0	1.0
ARRB2	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.011	0.057	0.316	9.0	-9999.0	0.0	9.0
ADRBK1	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.009	0.216	0.378	1.0	-0.766	15.0	16.0
STIL	0.02	0.204	0.346	7.0	-0.622	16.0	23.0
DHH N/PTCH2	-0.0	0.048	-9999.0	0.0	-0.684	1.0	1.0
DHH N/PTCH1	0.014	0.191	0.354	2.0	-0.658	15.0	17.0
PIK3CA	-0.003	0.054	-9999.0	0.0	-0.879	1.0	1.0
DHH	0.001	0.019	0.316	1.0	-9999.0	0.0	1.0
PTHLH	0.086	0.236	0.605	1.0	-0.852	8.0	9.0
determination of left/right symmetry	0.009	0.216	0.378	1.0	-0.766	15.0	16.0
PIK3R1	-0.003	0.054	-9999.0	0.0	-0.879	1.0	1.0
skeletal system development	0.086	0.234	0.604	1.0	-0.842	8.0	9.0
IHH N/Hhip	-0.356	0.39	-9999.0	0.0	-0.739	134.0	134.0
DHH N/Hhip	-0.331	0.345	-9999.0	0.0	-0.685	130.0	130.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.009	0.216	0.378	1.0	-0.766	15.0	16.0
pancreas development	-0.424	0.44	0.316	1.0	-0.877	130.0	131.0
HHAT	-0.001	0.06	0.316	2.0	-0.879	1.0	3.0
PI3K	-0.005	0.075	-9999.0	0.0	-1.234	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.137	0.321	0.316	1.0	-0.879	42.0	43.0
somite specification	0.009	0.216	0.378	1.0	-0.766	15.0	16.0
SHH Np/Cholesterol/PTCH1	-0.004	0.204	0.324	1.0	-0.612	21.0	22.0
SHH Np/Cholesterol/PTCH2	-0.022	0.124	-9999.0	0.0	-0.599	11.0	11.0
SHH Np/Cholesterol/Megalin	-0.083	0.227	-9999.0	0.0	-0.565	46.0	46.0
SHH	-0.01	0.148	-9999.0	0.0	-0.741	10.0	10.0
catabolic process	0.044	0.213	0.347	13.0	-0.723	15.0	28.0
SMO/Vitamin D3	0.003	0.228	0.42	1.0	-0.65	22.0	23.0
SHH Np/Cholesterol/Hhip	-0.29	0.292	-9999.0	0.0	-0.569	137.0	137.0
LRP2	-0.097	0.318	0.316	18.0	-0.879	36.0	54.0
receptor-mediated endocytosis	-0.044	0.243	-9999.0	0.0	-0.711	19.0	19.0
SHH Np/Cholesterol/BOC	-0.016	0.124	-9999.0	0.0	-0.6	10.0	10.0
SHH Np/Cholesterol/CDO	-0.022	0.119	-9999.0	0.0	-0.604	10.0	10.0
mesenchymal cell differentiation	0.287	0.29	0.564	137.0	-9999.0	0.0	137.0
mol:Vitamin D3	0.032	0.214	0.42	1.0	-0.613	21.0	22.0
IHH N/PTCH2	0.008	0.129	0.271	1.0	-0.603	9.0	10.0
CDON	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.034	0.228	0.4	16.0	-0.73	15.0	31.0
Megalin/LRPAP1	-0.077	0.245	-9999.0	0.0	-0.684	36.0	36.0
PTCH2	-0.001	0.06	0.316	2.0	-0.879	1.0	3.0
SHH Np/Cholesterol	-0.021	0.121	-9999.0	0.0	-0.611	10.0	10.0
PTCH1	0.044	0.214	0.348	13.0	-0.726	15.0	28.0
HHIP	-0.425	0.441	0.316	1.0	-0.879	130.0	131.0