Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.155 0.252 -9999.0 0.0 -0.621 28.0 28.0 MAP3K8 0.01 0.062 -9999.0 0.0 -0.689 2.0 2.0 FOS -0.086 0.177 -9999.0 0.0 -0.5 24.0 24.0 PRKCA 0.005 0.02 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.002 0.061 0.349 3.0 -0.692 1.0 4.0 HRAS 0.021 0.02 0.345 1.0 -9999.0 0.0 1.0 PRKCB -0.053 0.192 -9999.0 0.0 -0.682 22.0 22.0 NRAS 0.02 0.003 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.016 0.032 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.045 0.132 -9999.0 0.0 -0.659 7.0 7.0 MAP2K1 -0.059 0.162 -9999.0 0.0 -0.543 23.0 23.0 ELK1 -0.001 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.046 0.148 -9999.0 0.0 -0.515 22.0 22.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 115.0 115.0 MAPK1 -0.046 0.133 -9999.0 0.0 -0.633 8.0 8.0 RAF1 -0.044 0.143 -9999.0 0.0 -0.503 22.0 22.0 KRAS 0.02 0.004 -9999.0 0.0 -9999.0 0.0 0.0