Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.04 0.113 0.359 54.0 -9999.0 0.0 54.0 KIRREL -0.008 0.085 -9999.0 0.0 -0.501 14.0 14.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.04 0.113 -9999.0 0.0 -0.36 54.0 54.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.079 -9999.0 0.0 -0.259 4.0 4.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.006 0.057 -9999.0 0.0 -0.233 14.0 14.0 FYN -0.011 0.076 -9999.0 0.0 -0.224 54.0 54.0 mol:Ca2+ -0.028 0.078 -9999.0 0.0 -0.25 48.0 48.0 mol:DAG -0.028 0.079 -9999.0 0.0 -0.251 48.0 48.0 NPHS2 -0.002 0.015 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.028 0.079 -9999.0 0.0 -0.251 48.0 48.0 regulation of endocytosis -0.023 0.065 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.029 0.081 -9999.0 0.0 -0.258 54.0 54.0 establishment of cell polarity -0.04 0.113 -9999.0 0.0 -0.359 54.0 54.0 Nephrin/NEPH1/podocin/NCK1-2 -0.025 0.07 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.01 0.071 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.035 0.142 -9999.0 0.0 -0.51 40.0 40.0 Nephrin/NEPH1/podocin -0.025 0.071 -9999.0 0.0 -0.226 49.0 49.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.079 -9999.0 0.0 -0.252 48.0 48.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.028 0.079 -9999.0 0.0 -0.252 48.0 48.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.028 0.105 -9999.0 0.0 -0.29 34.0 34.0 cytoskeleton organization 0.008 0.066 -9999.0 0.0 -0.257 4.0 4.0 Nephrin/NEPH1 -0.028 0.078 -9999.0 0.0 -0.25 54.0 54.0 Nephrin/NEPH1/ZO-1 -0.031 0.087 -9999.0 0.0 -0.277 54.0 54.0