Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.036 0.059 0.236 6.0 -0.228 29.0 35.0 KIRREL 0.017 0.04 -9999.0 0.0 -0.33 6.0 6.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.036 0.059 0.228 29.0 -0.237 6.0 35.0 PLCG1 0.02 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.019 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.02 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.051 0.055 0.215 29.0 -0.179 6.0 35.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.015 0.039 -9999.0 0.0 -0.213 6.0 6.0 FYN 0.018 0.084 0.206 67.0 -0.172 6.0 73.0 mol:Ca2+ 0.048 0.053 0.207 28.0 -0.174 6.0 34.0 mol:DAG 0.049 0.054 0.211 28.0 -0.174 6.0 34.0 NPHS2 -0.004 0.023 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.049 0.054 0.211 28.0 -0.174 6.0 34.0 regulation of endocytosis 0.037 0.048 0.194 25.0 -0.166 6.0 31.0 Nephrin/NEPH1/podocin/Cholesterol 0.041 0.052 0.2 29.0 -0.173 6.0 35.0 establishment of cell polarity 0.036 0.059 0.228 29.0 -0.236 6.0 35.0 Nephrin/NEPH1/podocin/NCK1-2 0.06 0.056 0.276 1.0 -0.163 6.0 7.0 Nephrin/NEPH1/beta Arrestin2 0.038 0.049 0.201 25.0 -0.167 6.0 31.0 NPHS1 0.041 0.082 0.325 35.0 -9999.0 0.0 35.0 Nephrin/NEPH1/podocin 0.038 0.049 0.2 29.0 -0.172 6.0 35.0 TJP1 0.02 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.021 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.021 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.05 0.055 0.215 28.0 -0.175 6.0 34.0 CD2AP 0.02 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.051 0.055 0.215 28.0 -0.179 6.0 34.0 GRB2 0.02 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.008 0.093 0.218 60.0 -0.178 27.0 87.0 cytoskeleton organization -0.003 0.051 0.226 9.0 -0.218 6.0 15.0 Nephrin/NEPH1 0.031 0.046 0.187 29.0 -0.158 6.0 35.0 Nephrin/NEPH1/ZO-1 0.04 0.051 0.212 25.0 -0.188 6.0 31.0