Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.089	0.179	0.301	6.0	-0.489	43.0	49.0
IHH	-0.013	0.123	0.268	7.0	-0.37	42.0	49.0
SHH Np/Cholesterol/GAS1	-0.035	0.057	0.111	1.0	-0.179	61.0	62.0
LRPAP1	0.021	0.003	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.035	0.056	0.179	61.0	-0.11	1.0	62.0
SMO/beta Arrestin2	-0.143	0.181	0.289	3.0	-0.32	198.0	201.0
SMO	-0.145	0.184	0.275	2.0	-0.327	211.0	213.0
AKT1	-0.079	0.138	0.258	1.0	-0.479	30.0	31.0
ARRB2	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.016	-9999.0	0.0	-0.321	1.0	1.0
ADRBK1	0.021	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.144	0.181	0.274	2.0	-0.323	211.0	213.0
STIL	-0.083	0.14	0.209	23.0	-0.31	64.0	87.0
DHH N/PTCH2	0.01	0.069	-9999.0	0.0	-0.225	38.0	38.0
DHH N/PTCH1	-0.107	0.151	-9999.0	0.0	-0.235	235.0	235.0
PIK3CA	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.006	0.092	-9999.0	0.0	-0.321	38.0	38.0
PTHLH	-0.122	0.219	0.364	6.0	-0.547	41.0	47.0
determination of left/right symmetry	-0.144	0.181	0.274	2.0	-0.323	211.0	213.0
PIK3R1	0.019	0.016	-9999.0	0.0	-0.321	1.0	1.0
skeletal system development	-0.121	0.217	0.303	33.0	-0.543	41.0	74.0
IHH N/Hhip	-0.217	0.177	0.204	3.0	-0.312	355.0	358.0
DHH N/Hhip	-0.122	0.142	-9999.0	0.0	-0.244	268.0	268.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.144	0.181	0.274	2.0	-0.323	211.0	213.0
pancreas development	-0.163	0.17	-9999.0	0.0	-0.321	261.0	261.0
HHAT	0.018	0.023	-9999.0	0.0	-0.321	2.0	2.0
PI3K	0.028	0.014	-9999.0	0.0	-0.226	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.053	-9999.0	0.0	-0.321	12.0	12.0
somite specification	-0.144	0.181	0.274	2.0	-0.323	211.0	213.0
SHH Np/Cholesterol/PTCH1	-0.094	0.137	0.171	1.0	-0.327	67.0	68.0
SHH Np/Cholesterol/PTCH2	-0.033	0.051	0.111	1.0	-0.173	56.0	57.0
SHH Np/Cholesterol/Megalin	-0.066	0.084	0.111	1.0	-0.189	145.0	146.0
SHH	-0.038	0.068	0.15	1.0	-0.226	56.0	57.0
catabolic process	-0.105	0.158	0.224	2.0	-0.249	231.0	233.0
SMO/Vitamin D3	-0.115	0.173	0.37	3.0	-0.285	208.0	211.0
SHH Np/Cholesterol/Hhip	-0.102	0.099	0.111	1.0	-0.196	238.0	239.0
LRP2	-0.068	0.151	0.316	1.0	-0.321	126.0	127.0
receptor-mediated endocytosis	-0.159	0.183	0.297	2.0	-0.393	132.0	134.0
SHH Np/Cholesterol/BOC	-0.032	0.051	0.111	1.0	-0.173	55.0	56.0
SHH Np/Cholesterol/CDO	-0.034	0.055	0.111	1.0	-0.177	59.0	60.0
mesenchymal cell differentiation	0.102	0.099	0.195	238.0	-0.11	1.0	239.0
mol:Vitamin D3	-0.091	0.149	0.237	17.0	-0.329	67.0	84.0
IHH N/PTCH2	-0.094	0.127	0.204	4.0	-0.207	262.0	266.0
CDON	0.014	0.046	-9999.0	0.0	-0.321	9.0	9.0
IHH N/PTCH1	-0.097	0.17	0.226	35.0	-0.25	234.0	269.0
Megalin/LRPAP1	-0.034	0.112	0.229	1.0	-0.225	123.0	124.0
PTCH2	0.02	0.016	-9999.0	0.0	-0.321	1.0	1.0
SHH Np/Cholesterol	-0.028	0.051	-9999.0	0.0	-0.168	56.0	56.0
PTCH1	-0.106	0.158	0.225	2.0	-0.249	231.0	233.0
HHIP	-0.163	0.17	-9999.0	0.0	-0.321	261.0	261.0