Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.036 0.174 -9999.0 0.0 -0.88 1.0 1.0 MAP3K8 0.016 0.114 -9999.0 0.0 -0.619 1.0 1.0 FOS 0.034 0.108 -9999.0 0.0 -0.522 1.0 1.0 PRKCA 0.007 0.123 -9999.0 0.0 -0.421 2.0 2.0 PTPN7 0.031 0.017 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.035 0.009 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.0 0.003 -9999.0 0.0 -0.008 5.0 5.0 NRAS 0.021 0.059 -9999.0 0.0 -0.207 2.0 2.0 RAS family/GTP 0.041 0.055 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.035 0.056 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 0.005 0.12 -9999.0 0.0 -0.59 1.0 1.0 ELK1 0.033 0.015 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.001 0.097 -9999.0 0.0 -0.529 1.0 1.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.003 5.0 5.0 MAPK1 0.036 0.056 -9999.0 0.0 -9999.0 0.0 0.0 RAF1 0.0 0.097 -9999.0 0.0 -0.529 1.0 1.0 KRAS 0.016 0.06 -9999.0 0.0 -0.209 2.0 2.0