Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 141 (79%) 37 0.04397 1 0.02632 1 0.00059999 0.107 0.00147 0.259 1 1 0.70015 1 0.0050099 0.872 0.02328 1 0.40693 1 0.44084 1 0.089499 1 0.063949 1 NFE2L2 27 (15%) 151 0.00027 0.0486 0.00013 0.0235 0.01376 1 0.0361 1 0.25285 1 0.73841 1 9.9999e-06 0.00184 9.9999e-06 0.00184 0.0059799 1 5e-05 0.0091 0.62813 1 0.86569 1 CDKN2A 26 (15%) 152 0.00162 0.283 0.0055499 0.96 0.02455 1 0.66726 1 0.33945 1 0.16945 1 0.37963 1 0.089149 1 0.66359 1 0.81907 1 0.84325 1 0.02991 1 KEAP1 22 (12%) 156 0.00145 0.257 0.00061999 0.11 0.11881 1 0.075409 1 0.20165 1 0.14783 1 0.1868 1 0.02975 1 0.18097 1 0.44685 1 0.48053 1 0.66934 1 PTEN 14 (8%) 164 0.38074 1 0.32322 1 0.41219 1 0.13503 1 0.7221 1 0.96109 1 0.59426 1 0.51122 1 0.57253 1 0.51272 1 0.19894 1 1 1 PIK3CA 27 (15%) 151 0.69017 1 0.75361 1 0.29067 1 0.54569 1 1 1 0.666 1 0.33936 1 0.58553 1 0.36388 1 0.37868 1 0.72372 1 0.75293 1 MLL2 35 (20%) 143 0.16787 1 0.4643 1 0.64569 1 0.31431 1 0.69736 1 0.36287 1 0.32431 1 0.85624 1 0.9303 1 0.94107 1 0.74337 1 1 1 RB1 12 (7%) 166 0.31305 1 0.64566 1 0.52409 1 0.10681 1 0.65602 1 0.48038 1 0.77484 1 0.24056 1 0.32206 1 0.75375 1 NA NA NA NA IBTK 5 (3%) 173 0.48937 1 0.84678 1 0.73906 1 NA NA NA NA NA NA 0.80713 1 0.84167 1 1 1 0.6076 1 NA NA NA NA CYP11B1 15 (8%) 163 0.65261 1 0.67697 1 0.65883 1 0.12517 1 0.23957 1 0.094419 1 0.56992 1 0.36768 1 0.56248 1 0.97652 1 NA NA NA NA NOTCH1 14 (8%) 164 0.81558 1 0.60326 1 0.46807 1 0.03454 1 0.58981 1 0.6284 1 0.75603 1 0.39161 1 0.34926 1 0.31992 1 0.01033 1 0.0296 1 SLC28A1 9 (5%) 169 0.01362 1 0.050109 1 0.079299 1 0.13368 1 0.31997 1 0.52344 1 0.03673 1 0.02812 1 0.18513 1 0.01692 1 0.81878 1 0.1832 1 ASB5 9 (5%) 169 0.49575 1 0.54967 1 0.26318 1 NA NA 0.47162 1 1 1 0.48036 1 0.49686 1 0.252 1 0.33679 1 NA NA NA NA CPS1 25 (14%) 153 0.76785 1 0.23465 1 0.26705 1 0.89166 1 0.73072 1 0.49771 1 0.99018 1 0.72596 1 0.03786 1 0.27889 1 1 1 1 1 EP300 8 (4%) 170 0.14966 1 0.11794 1 0.43704 1 NA NA 0.35668 1 1 1 0.081129 1 0.083029 1 0.57016 1 0.82233 1 NA NA NA NA ARID1A 12 (7%) 166 0.31299 1 0.55249 1 0.45208 1 0.35406 1 0.49491 1 0.60133 1 0.11104 1 0.86188 1 0.52965 1 0.69242 1 NA NA NA NA FBXW7 10 (6%) 168 0.49299 1 0.82956 1 0.069979 1 NA NA 0.62311 1 0.78833 1 0.83344 1 0.52632 1 0.96234 1 0.067209 1 NA NA NA NA