Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.248 0.284 0.517 42.0 -9999.0 0.0 42.0 KIRREL -0.088 0.221 -9999.0 0.0 -0.686 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.249 0.285 -9999.0 0.0 -0.518 42.0 42.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.197 0.218 -9999.0 0.0 -0.434 32.0 32.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.137 0.203 -9999.0 0.0 -0.359 32.0 32.0 FYN -0.182 0.223 -9999.0 0.0 -0.411 34.0 34.0 mol:Ca2+ -0.195 0.216 -9999.0 0.0 -0.43 32.0 32.0 mol:DAG -0.196 0.217 -9999.0 0.0 -0.432 32.0 32.0 NPHS2 -0.041 0.093 -9999.0 0.0 -0.6 2.0 2.0 mol:IP3 -0.196 0.217 -9999.0 0.0 -0.432 32.0 32.0 regulation of endocytosis -0.164 0.211 -9999.0 0.0 -0.388 32.0 32.0 Nephrin/NEPH1/podocin/Cholesterol -0.201 0.222 -9999.0 0.0 -0.404 42.0 42.0 establishment of cell polarity -0.248 0.284 -9999.0 0.0 -0.517 42.0 42.0 Nephrin/NEPH1/podocin/NCK1-2 -0.181 0.212 -9999.0 0.0 -0.612 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.166 0.215 -9999.0 0.0 -0.393 32.0 32.0 NPHS1 -0.278 0.319 -9999.0 0.0 -0.63 38.0 38.0 Nephrin/NEPH1/podocin -0.184 0.223 -9999.0 0.0 -0.413 34.0 34.0 TJP1 0.006 0.073 -9999.0 0.0 -0.66 1.0 1.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.006 0.073 -9999.0 0.0 -0.66 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.197 0.218 -9999.0 0.0 -0.434 32.0 32.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.197 0.218 -9999.0 0.0 -0.434 32.0 32.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.203 0.235 -9999.0 0.0 -0.42 38.0 38.0 cytoskeleton organization -0.168 0.24 -9999.0 0.0 -0.439 32.0 32.0 Nephrin/NEPH1 -0.181 0.215 -9999.0 0.0 -0.38 42.0 42.0 Nephrin/NEPH1/ZO-1 -0.21 0.241 -9999.0 0.0 -0.424 42.0 42.0