Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.135 0.209 0.414 27.0 -9999.0 0.0 27.0 KIRREL -0.056 0.167 -9999.0 0.0 -0.531 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.135 0.209 -9999.0 0.0 -0.415 27.0 27.0 PLCG1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.086 0.173 -9999.0 0.0 -0.309 28.0 28.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.084 0.158 -9999.0 0.0 -0.299 25.0 25.0 FYN -0.089 0.172 0.27 4.0 -0.302 27.0 31.0 mol:Ca2+ -0.088 0.172 -9999.0 0.0 -0.306 29.0 29.0 mol:DAG -0.088 0.173 -9999.0 0.0 -0.307 29.0 29.0 NPHS2 -0.023 0.056 -9999.0 0.0 -0.269 2.0 2.0 mol:IP3 -0.088 0.173 -9999.0 0.0 -0.307 29.0 29.0 regulation of endocytosis -0.081 0.158 -9999.0 0.0 -0.286 27.0 27.0 Nephrin/NEPH1/podocin/Cholesterol -0.095 0.167 -9999.0 0.0 -0.307 29.0 29.0 establishment of cell polarity -0.135 0.209 -9999.0 0.0 -0.414 27.0 27.0 Nephrin/NEPH1/podocin/NCK1-2 -0.073 0.178 -9999.0 0.0 -0.298 27.0 27.0 Nephrin/NEPH1/beta Arrestin2 -0.081 0.16 -9999.0 0.0 -0.29 27.0 27.0 NPHS1 -0.161 0.232 -9999.0 0.0 -0.415 36.0 36.0 Nephrin/NEPH1/podocin -0.092 0.162 -9999.0 0.0 -0.304 27.0 27.0 TJP1 0.02 0.057 -9999.0 0.0 -0.501 1.0 1.0 NCK1 0.029 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.022 0.057 -9999.0 0.0 -0.501 1.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.087 0.175 -9999.0 0.0 -0.308 29.0 29.0 CD2AP 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.091 0.172 -9999.0 0.0 -0.308 29.0 29.0 GRB2 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.098 0.178 0.279 4.0 -0.299 30.0 34.0 cytoskeleton organization -0.105 0.188 0.204 4.0 -0.36 25.0 29.0 Nephrin/NEPH1 -0.092 0.152 -9999.0 0.0 -0.294 27.0 27.0 Nephrin/NEPH1/ZO-1 -0.102 0.187 -9999.0 0.0 -0.343 27.0 27.0