Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL MIR_CNMF MIR_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p34.3 292 (50%) 287 0.43073 1 0.081279 1 0.12503 1 0.085069 1 9.9999e-06 0.00986 0.19505 1 0.11201 1 0.38767 1 0.55543 1 0.18437 1 0.088169 1 0.16256 1 0.074303 1 0.92691 1 amp_1q21.3 367 (63%) 212 0.26901 1 0.16325 1 0.64021 1 0.39888 1 9.9999e-06 0.00986 0.00022 0.202 0.076669 1 0.071069 1 0.6573 1 0.37142 1 0.84129 1 0.0062799 1 0.6517 1 0.69547 1 amp_1q42.2 322 (56%) 257 0.02339 1 0.0274 1 0.88447 1 0.0077899 1 9.9999e-06 0.00986 8.9999e-05 0.0834 0.25668 1 0.12406 1 0.50623 1 0.3194 1 0.26474 1 0.00297 1 1 1 0.5102 1 amp_2p23.2 252 (44%) 327 0.32635 1 0.01349 1 0.75937 1 0.17139 1 9.9999e-06 0.00986 0.00441 1 0.14473 1 0.21345 1 0.03174 1 0.0202 1 0.92 1 0.20199 1 1 1 0.671 1 amp_2q31.2 262 (45%) 317 0.11431 1 0.17341 1 0.03407 1 0.02977 1 9.9999e-06 0.00986 0.0075399 1 0.04909 1 0.32079 1 0.15125 1 0.27071 1 0.28648 1 0.086909 1 0.66992 1 0.88847 1 amp_3q26.2 485 (84%) 94 0.0090599 1 0.02555 1 0.81816 1 0.28002 1 9.9999e-06 0.00986 0.03558 1 0.40549 1 0.27981 1 0.0070299 1 0.01139 1 0.12535 1 0.067889 1 1 1 0.57776 1 amp_4p16.3 160 (28%) 419 1 1 0.3201 1 0.02927 1 0.47875 1 0.00042 0.381 0.02766 1 0.27045 1 0.6876 1 0.68721 1 0.98282 1 0.62861 1 0.01872 1 0.6517 1 0.57876 1 amp_4q13.3 113 (20%) 466 0.90521 1 0.4647 1 0.38721 1 0.98604 1 0.00025 0.228 0.52236 1 0.61659 1 0.53923 1 0.18244 1 0.4839 1 0.96554 1 0.69342 1 0.32331 1 0.6958 1 amp_5p15.33 309 (53%) 270 1 1 0.055259 1 0.62648 1 0.2505 1 9.9999e-06 0.00986 0.097239 1 0.98115 1 0.23683 1 0.24273 1 0.39079 1 0.02447 1 0.14808 1 0.23053 1 0.26824 1 amp_6p22.3 306 (53%) 273 0.17623 1 0.03015 1 0.27495 1 0.072849 1 9.9999e-06 0.00986 0.01203 1 0.073609 1 0.056609 1 0.86663 1 0.21294 1 0.37818 1 0.61419 1 1 1 0.25366 1 amp_7q36.3 320 (55%) 259 0.10603 1 0.17832 1 0.36016 1 0.98878 1 3e-05 0.0281 0.45528 1 0.0319 1 0.20097 1 0.84479 1 0.97019 1 0.21128 1 0.50241 1 0.19838 1 0.26257 1 amp_8p11.21 211 (36%) 368 0.1098 1 0.35177 1 0.10191 1 0.53274 1 9.9999e-06 0.00986 0.01615 1 0.01102 1 0.41991 1 0.27911 1 0.17248 1 0.76908 1 0.32611 1 0.23053 1 0.85767 1 amp_8q24.21 461 (80%) 118 9.9999e-06 0.00986 9.9999e-06 0.00986 0.24662 1 0.00262 1 9.9999e-06 0.00986 0.00443 1 0.98656 1 0.32451 1 9.9999e-06 0.00986 0.00029 0.264 0.16072 1 0.097639 1 0.57143 1 0.57117 1 amp_10p15.3 252 (44%) 327 0.82278 1 0.10167 1 0.053609 1 0.16465 1 9.9999e-06 0.00986 0.00043 0.39 0.48848 1 0.50081 1 0.24228 1 0.12148 1 0.3779 1 0.067539 1 1 1 0.60765 1 amp_10q22.3 184 (32%) 395 0.37068 1 0.2655 1 0.60843 1 0.94922 1 0.078799 1 0.84253 1 0.7719 1 0.8197 1 0.34181 1 0.89803 1 0.22822 1 0.64752 1 0.66992 1 0.30271 1 amp_11q14.1 257 (44%) 322 0.0052799 1 0.00385 1 0.77319 1 0.31042 1 9.9999e-06 0.00986 0.00263 1 0.3804 1 0.22799 1 0.00457 1 0.0268 1 0.13122 1 0.92308 1 0.042731 1 0.43513 1 amp_12p13.33 330 (57%) 249 0.02295 1 0.00345 1 0.26256 1 0.054839 1 9.9999e-06 0.00986 0.00014 0.129 0.19633 1 0.15125 1 0.0146 1 0.03108 1 0.53542 1 0.0077099 1 0.37771 1 0.52866 1 amp_12p12.1 313 (54%) 266 0.12704 1 0.30583 1 0.9002 1 0.04116 1 9.9999e-06 0.00986 3e-05 0.0281 0.61501 1 0.090469 1 0.01169 1 0.30127 1 0.44157 1 0.00492 1 0.39128 1 0.04137 1 amp_12q15 222 (38%) 357 0.0028 1 0.24197 1 0.57413 1 0.0023 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.073129 1 0.24919 1 0.00141 1 0.071369 1 0.96758 1 0.10059 1 0.23053 1 0.26923 1 amp_14q11.2 148 (26%) 431 0.01684 1 0.059229 1 0.28986 1 0.0066899 1 0.068689 1 0.19306 1 0.53183 1 0.46965 1 0.34033 1 0.41051 1 0.30044 1 0.82179 1 0.32331 1 0.27748 1 amp_14q32.33 156 (27%) 423 0.43729 1 0.65254 1 0.19807 1 0.01718 1 5e-05 0.0466 0.2891 1 1 1 0.20327 1 0.16647 1 0.24103 1 0.37315 1 0.42298 1 0.096377 1 0.13945 1 amp_15q26.3 163 (28%) 416 0.084049 1 0.42628 1 0.50729 1 0.42577 1 9.9999e-06 0.00986 0.80518 1 0.97813 1 0.18035 1 0.20332 1 0.54815 1 0.15503 1 0.064769 1 0.67492 1 0.78451 1 amp_17q25.3 215 (37%) 364 0.46831 1 0.056069 1 0.9815 1 0.66482 1 0.00382 1 0.77361 1 0.072749 1 0.1283 1 0.01186 1 0.02594 1 0.32575 1 0.12875 1 1 1 0.70948 1 amp_18q11.2 143 (25%) 436 0.82294 1 0.78211 1 0.95317 1 0.2218 1 9.9999e-06 0.00986 0.00386 1 0.1563 1 0.42024 1 0.04223 1 0.076099 1 0.14798 1 0.51137 1 0.3808 1 0.093049 1 amp_19p13.12 315 (54%) 264 0.00019 0.175 0.00025 0.228 0.03713 1 0.25092 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.00035 0.318 9.9999e-05 0.0924 0.24 1 0.46493 1 0.58608 1 0.098509 1 1 1 0.481 1 amp_19q12 322 (56%) 257 0.12458 1 0.0061899 1 0.0295 1 0.51255 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.04714 1 0.21331 1 0.55202 1 0.37465 1 0.34624 1 0.059959 1 1 1 0.78193 1 amp_19q13.2 245 (42%) 334 0.94508 1 0.5371 1 0.6647 1 0.39002 1 9.9999e-06 0.00986 0.00011 0.102 0.44744 1 0.14607 1 0.38181 1 0.086949 1 0.97736 1 0.5523 1 0.67492 1 0.61248 1 amp_20p13 317 (55%) 262 0.18767 1 0.0057099 1 0.20673 1 0.03323 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.32149 1 0.57326 1 0.01655 1 0.34829 1 0.24814 1 0.00081999 0.736 1 1 0.93614 1 amp_20q11.21 348 (60%) 231 0.00271 1 0.00303 1 0.11206 1 0.00296 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.12994 1 0.01928 1 0.00019 0.175 0.04737 1 0.29179 1 0.00053999 0.488 1 1 0.33476 1 amp_20q13.33 402 (69%) 177 0.01069 1 0.00087999 0.789 0.68308 1 0.00125 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.85083 1 0.27902 1 0.0084099 1 0.00475 1 0.47723 1 0.04914 1 0.62406 1 0.01392 1 amp_22q12.2 91 (16%) 488 0.62348 1 0.15707 1 0.069759 1 0.03587 1 0.0076199 1 0.00060999 0.55 0.98331 1 0.091119 1 0.059099 1 0.059529 1 0.10792 1 0.01436 1 1 1 0.086489 1 amp_xp11.23 159 (27%) 420 0.66398 1 0.86734 1 0.41849 1 0.6319 1 9.9999e-06 0.00986 0.00169 1 0.71767 1 0.90198 1 0.44791 1 0.92946 1 0.27698 1 0.0318 1 0.67492 1 0.634 1 amp_xq28 220 (38%) 359 0.24546 1 0.84756 1 0.55503 1 0.12257 1 0.00047 0.425 0.17791 1 0.45566 1 0.44424 1 0.62743 1 0.93856 1 0.87795 1 0.80151 1 0.042731 1 0.6237 1 del_1p36.11 269 (46%) 310 0.73773 1 0.068729 1 0.02938 1 0.11681 1 5.9999e-05 0.0558 0.088929 1 0.12523 1 0.3923 1 0.85221 1 0.42028 1 0.21977 1 0.17074 1 0.67492 1 0.97783 1 del_1q41 97 (17%) 482 0.088409 1 0.62501 1 0.29922 1 0.83698 1 9.9999e-06 0.00986 0.13539 1 0.48716 1 0.01794 1 0.28199 1 0.24611 1 0.92119 1 0.97015 1 0.45455 1 NA NA del_2p25.3 120 (21%) 459 0.88101 1 0.26727 1 0.42186 1 0.15915 1 0.40124 1 0.63763 1 0.26076 1 0.54221 1 0.063169 1 0.23903 1 0.87558 1 0.95044 1 0.3808 1 0.42596 1 del_2q22.1 137 (24%) 442 0.10604 1 0.27304 1 0.56809 1 0.00388 1 0.076739 1 0.66459 1 0.6038 1 0.71877 1 0.91947 1 0.30065 1 0.4788 1 0.60275 1 1 1 0.26566 1 del_2q37.3 175 (30%) 404 0.01592 1 0.46431 1 0.63461 1 0.02691 1 2e-05 0.0188 0.088229 1 0.74787 1 0.58757 1 0.014 1 0.00236 1 0.02286 1 0.01919 1 0.32331 1 0.96637 1 del_3p26.2 209 (36%) 370 0.15571 1 0.00056999 0.515 0.0058199 1 0.00437 1 8.9999e-05 0.0834 0.00056999 0.515 0.97031 1 0.23971 1 0.00293 1 0.0098199 1 0.63011 1 0.12315 1 0.41486 1 0.94026 1 del_3q13.31 84 (15%) 495 0.32845 1 0.22706 1 0.56838 1 0.62556 1 0.10989 1 0.082549 1 0.24993 1 0.45342 1 0.40651 1 0.39603 1 0.51937 1 0.52331 1 1 1 NA NA del_4q22.1 394 (68%) 185 0.053499 1 0.02374 1 1 1 0.16573 1 0.01547 1 0.22539 1 0.19088 1 0.061489 1 0.070969 1 0.38801 1 0.30291 1 0.25475 1 0.67492 1 0.41302 1 del_4q34.3 421 (73%) 158 0.053339 1 0.00074999 0.674 0.062629 1 0.02811 1 0.18418 1 0.57997 1 0.66904 1 0.19855 1 0.083919 1 0.01929 1 0.4197 1 0.52966 1 1 1 0.5601 1 del_5q12.1 355 (61%) 224 0.88343 1 0.87382 1 0.57732 1 0.055829 1 9.9999e-06 0.00986 2e-04 0.183 0.68483 1 0.86313 1 0.29543 1 0.054139 1 0.16159 1 0.25266 1 1 1 0.26275 1 del_5q13.2 419 (72%) 160 0.74719 1 0.62339 1 0.89974 1 0.25723 1 9.9999e-06 0.00986 0.1044 1 0.79124 1 0.83053 1 0.51733 1 0.092359 1 0.15536 1 0.1071 1 1 1 0.7225 1 del_6q27 380 (66%) 199 0.32289 1 0.061169 1 0.27135 1 0.10339 1 9.9999e-06 0.00986 4e-05 0.0373 0.61969 1 0.55975 1 2e-05 0.0188 0.0016 1 0.56075 1 0.02598 1 0.69136 1 0.43566 1 del_7p22.1 253 (44%) 326 0.39431 1 0.51382 1 0.77052 1 0.061399 1 9.9999e-06 0.00986 0.62608 1 0.81764 1 0.6023 1 0.34693 1 0.12677 1 0.34881 1 0.90511 1 0.23053 1 0.78397 1 del_8p23.3 388 (67%) 191 0.04479 1 0.1517 1 0.57248 1 0.01152 1 9.9999e-06 0.00986 0.051489 1 0.89162 1 0.44945 1 0.89488 1 0.91245 1 0.24713 1 0.24877 1 1 1 NA NA del_8p21.2 406 (70%) 173 0.0425 1 0.091869 1 0.18316 1 0.0052199 1 9.9999e-06 0.00986 0.14659 1 0.87537 1 0.9942 1 0.45795 1 0.70064 1 0.58003 1 0.5179 1 1 1 NA NA del_9p24.3 261 (45%) 318 0.00026 0.237 9.9999e-06 0.00986 0.6227 1 0.01323 1 0.061479 1 6.9999e-05 0.065 0.32139 1 0.95478 1 0.072569 1 0.051619 1 0.088599 1 0.12553 1 1 1 0.51377 1 del_9q34.13 342 (59%) 237 0.01699 1 0.00088999 0.797 0.6983 1 0.4101 1 9.9999e-06 0.00986 0.01829 1 0.67469 1 0.1627 1 0.077429 1 0.080649 1 0.050329 1 0.10037 1 1 1 0.79291 1 del_10p15.3 120 (21%) 459 0.17867 1 0.70917 1 0.086969 1 0.31926 1 0.097159 1 0.35079 1 0.28998 1 0.04089 1 0.01429 1 0.088889 1 0.25263 1 0.26558 1 0.59398 1 0.10531 1 del_10q24.2 251 (43%) 328 0.00318 1 0.00276 1 0.0072999 1 0.23646 1 8.9999e-05 0.0834 0.00196 1 0.0162 1 0.00243 1 0.532 1 0.36545 1 0.00187 1 0.36798 1 1 1 0.78422 1 del_11p15.5 346 (60%) 233 0.1108 1 0.97077 1 0.61893 1 0.085469 1 9.9999e-06 0.00986 0.0075799 1 0.9456 1 0.71051 1 0.70008 1 0.50585 1 0.10612 1 0.0086399 1 0.20433 1 0.92671 1 del_11q25 201 (35%) 378 0.62347 1 0.65196 1 0.20916 1 0.053169 1 0.27259 1 0.41691 1 0.3218 1 0.26738 1 0.93094 1 0.45365 1 0.70776 1 0.27371 1 1 1 0.76849 1 del_12q24.33 220 (38%) 359 0.00112 1 0.099239 1 0.16321 1 0.01456 1 9.9999e-06 0.00986 0.01978 1 0.29238 1 0.2239 1 0.050309 1 0.03209 1 0.01552 1 0.00464 1 0.64617 1 1 1 del_13q14.2 364 (63%) 215 0.01047 1 0.01549 1 0.61327 1 0.04292 1 0.00024 0.219 9.9999e-06 0.00986 0.00219 1 0.052009 1 0.099139 1 0.67748 1 0.37693 1 0.36667 1 0.67492 1 0.24869 1 del_14q23.3 305 (53%) 274 0.065639 1 0.50637 1 0.65067 1 0.60925 1 5.9999e-05 0.0558 0.73721 1 0.22951 1 0.50755 1 0.85612 1 0.28223 1 0.89972 1 0.59464 1 0.66563 1 0.13966 1 del_15q11.2 299 (52%) 280 0.0054599 1 0.03542 1 0.01062 1 0.0061999 1 9.9999e-06 0.00986 3e-05 0.0281 0.46777 1 0.76631 1 0.0050899 1 0.15859 1 0.02583 1 0.0097299 1 1 1 0.37158 1 del_15q15.1 363 (63%) 216 0.02587 1 0.059619 1 0.0211 1 0.00285 1 9.9999e-06 0.00986 9.9999e-06 0.00986 0.15607 1 0.15246 1 0.01151 1 0.50002 1 0.39548 1 0.00184 1 0.20433 1 0.14351 1 del_16p13.3 313 (54%) 266 0.60185 1 0.071849 1 0.27446 1 0.02947 1 0.10765 1 0.4195 1 0.84009 1 0.82103 1 0.37037 1 0.42617 1 0.22404 1 0.48454 1 0.67492 1 0.78685 1 del_16q22.1 461 (80%) 118 0.4993 1 0.7062 1 0.03189 1 0.44946 1 0.00088999 0.797 0.64 1 0.69445 1 0.14298 1 0.22063 1 0.28531 1 0.31341 1 0.04821 1 1 1 0.38515 1 del_16q23.1 452 (78%) 127 0.10823 1 0.24316 1 0.10261 1 0.060589 1 0.00015 0.138 0.5382 1 0.81182 1 0.22654 1 0.27354 1 0.16881 1 0.056849 1 0.04842 1 1 1 0.90231 1 del_17p12 491 (85%) 88 0.14253 1 0.33641 1 0.59479 1 0.68963 1 0.70865 1 0.32186 1 0.90733 1 0.37057 1 0.15368 1 0.19434 1 0.50356 1 0.21026 1 1 1 NA NA del_17q11.2 472 (82%) 107 0.92084 1 0.18995 1 0.73351 1 0.2172 1 0.00071999 0.648 0.00276 1 0.76668 1 0.03588 1 0.37313 1 0.43882 1 0.15126 1 0.16352 1 1 1 0.33862 1 del_18q23 381 (66%) 198 0.88336 1 0.85401 1 0.36907 1 0.95734 1 0.00275 1 0.58735 1 0.48009 1 0.1848 1 0.15176 1 0.36242 1 0.66049 1 0.49201 1 0.64617 1 0.79393 1 del_19p13.3 512 (88%) 67 0.15788 1 0.090999 1 0.83891 1 0.54738 1 0.00034 0.309 0.01814 1 0.62239 1 0.40456 1 0.33452 1 0.5168 1 0.4774 1 0.73238 1 1 1 NA NA del_19q13.33 299 (52%) 280 0.00023 0.21 0.00229 1 0.0457 1 0.01994 1 0.01428 1 0.00278 1 0.02895 1 0.30066 1 0.0062799 1 0.12296 1 0.32142 1 0.12951 1 0.39128 1 0.11157 1 del_19q13.43 285 (49%) 294 0.01666 1 0.081749 1 0.079869 1 0.38582 1 0.00011 0.102 5e-05 0.0466 0.16122 1 0.48849 1 0.56367 1 0.98474 1 0.51762 1 0.12071 1 0.042731 1 0.02136 1 del_21q22.3 227 (39%) 352 0.37099 1 0.04166 1 0.69333 1 0.20494 1 0.79513 1 0.26302 1 0.65926 1 0.71438 1 0.24571 1 0.12729 1 0.82008 1 0.72697 1 0.16188 1 0.92781 1 del_22q13.32 503 (87%) 76 0.20902 1 0.12288 1 0.03524 1 0.28465 1 0.01751 1 0.159 1 0.12199 1 0.04468 1 0.16945 1 0.01358 1 0.03657 1 0.57671 1 NA NA NA NA del_xp21.1 355 (61%) 224 0.40466 1 0.64427 1 0.099819 1 0.80032 1 0.16702 1 0.02033 1 0.46118 1 0.10834 1 0.88473 1 0.23812 1 0.97583 1 0.71589 1 0.59398 1 0.28218 1