Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.079 0.171 0.458 33.0 -9999.0 0.0 33.0 KIRREL -0.003 0.043 -9999.0 0.0 -0.44 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.08 0.171 -9999.0 0.0 -0.459 33.0 33.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.106 -9999.0 0.0 -0.304 25.0 25.0 FYN -0.055 0.128 -9999.0 0.0 -0.346 34.0 34.0 mol:Ca2+ -0.065 0.126 -9999.0 0.0 -0.36 32.0 32.0 mol:DAG -0.052 0.133 -9999.0 0.0 -0.362 32.0 32.0 NPHS2 -0.018 0.07 -9999.0 0.0 -0.419 7.0 7.0 mol:IP3 -0.052 0.133 -9999.0 0.0 -0.362 32.0 32.0 regulation of endocytosis -0.045 0.122 -9999.0 0.0 -0.321 34.0 34.0 Nephrin/NEPH1/podocin/Cholesterol -0.06 0.133 -9999.0 0.0 -0.37 32.0 32.0 establishment of cell polarity -0.079 0.171 -9999.0 0.0 -0.458 33.0 33.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.123 -9999.0 0.0 -0.327 32.0 32.0 Nephrin/NEPH1/beta Arrestin2 -0.044 0.123 -9999.0 0.0 -0.325 34.0 34.0 NPHS1 -0.116 0.226 -9999.0 0.0 -0.498 64.0 64.0 Nephrin/NEPH1/podocin -0.055 0.129 -9999.0 0.0 -0.348 34.0 34.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.052 0.134 -9999.0 0.0 -0.363 32.0 32.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.056 0.129 -9999.0 0.0 -0.334 37.0 37.0 cytoskeleton organization -0.037 0.132 -9999.0 0.0 -0.379 27.0 27.0 Nephrin/NEPH1 -0.054 0.122 -9999.0 0.0 -0.329 33.0 33.0 Nephrin/NEPH1/ZO-1 -0.054 0.138 -9999.0 0.0 -0.386 28.0 28.0