Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.002 0.112 0.367 21.0 -9999.0 0.0 21.0 KIRREL 0.023 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.002 0.112 -9999.0 0.0 -0.368 21.0 21.0 PLCG1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.028 0.094 -9999.0 0.0 -0.276 20.0 20.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.078 -9999.0 0.0 -0.26 20.0 20.0 FYN -0.006 0.094 0.335 2.0 -0.257 22.0 24.0 mol:Ca2+ 0.025 0.094 -9999.0 0.0 -0.275 21.0 21.0 mol:DAG 0.026 0.095 -9999.0 0.0 -0.276 21.0 21.0 NPHS2 0.012 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.026 0.095 -9999.0 0.0 -0.276 21.0 21.0 regulation of endocytosis 0.023 0.085 -9999.0 0.0 -0.247 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol 0.015 0.089 -9999.0 0.0 -0.273 21.0 21.0 establishment of cell polarity 0.002 0.112 -9999.0 0.0 -0.367 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.093 -9999.0 0.0 -0.255 20.0 20.0 Nephrin/NEPH1/beta Arrestin2 0.025 0.086 -9999.0 0.0 -0.25 21.0 21.0 NPHS1 -0.03 0.148 -9999.0 0.0 -0.496 23.0 23.0 Nephrin/NEPH1/podocin 0.016 0.086 -9999.0 0.0 -0.258 22.0 22.0 TJP1 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.027 0.096 -9999.0 0.0 -0.277 21.0 21.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.029 0.094 -9999.0 0.0 -0.276 20.0 20.0 GRB2 0.029 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.015 0.094 0.347 2.0 -0.254 22.0 24.0 cytoskeleton organization -0.021 0.092 0.201 1.0 -0.33 19.0 20.0 Nephrin/NEPH1 0.006 0.08 -9999.0 0.0 -0.256 21.0 21.0 Nephrin/NEPH1/ZO-1 0.017 0.096 -9999.0 0.0 -0.294 21.0 21.0