Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.031	0.111	0.493	12.0	-0.445	16.0	28.0
IHH	-0.005	0.077	0.157	88.0	-9999.0	0.0	88.0
SHH Np/Cholesterol/GAS1	-0.045	0.037	0.142	1.0	-0.131	77.0	78.0
LRPAP1	0.028	0.007	-9999.0	0.0	0.0	33.0	33.0
dorsoventral neural tube patterning	0.044	0.037	0.131	77.0	-0.14	1.0	78.0
SMO/beta Arrestin2	0.026	0.132	0.293	84.0	-0.388	9.0	93.0
SMO	0.028	0.132	0.302	84.0	-0.398	9.0	93.0
AKT1	-0.024	0.147	0.268	13.0	-0.442	19.0	32.0
ARRB2	0.028	0.006	-9999.0	0.0	0.0	25.0	25.0
BOC	0.026	0.01	-9999.0	0.0	0.0	80.0	80.0
ADRBK1	0.029	0.003	-9999.0	0.0	0.0	6.0	6.0
heart looping	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
STIL	0.001	0.064	0.27	20.0	-9999.0	0.0	20.0
DHH N/PTCH2	0.042	0.009	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.132	0.31	79.0	-0.253	24.0	103.0
PIK3CA	0.021	0.014	-9999.0	0.0	0.0	174.0	174.0
DHH	0.03	0.003	-9999.0	0.0	0.0	4.0	4.0
PTHLH	0.032	0.19	0.486	71.0	-0.427	14.0	85.0
determination of left/right symmetry	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
PIK3R1	0.021	0.013	-9999.0	0.0	0.0	159.0	159.0
skeletal system development	0.032	0.19	0.485	71.0	-0.424	14.0	85.0
IHH N/Hhip	0.049	0.041	0.179	3.0	-0.088	8.0	11.0
DHH N/Hhip	0.042	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
pancreas development	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0
HHAT	0.029	0.006	-9999.0	0.0	0.0	20.0	20.0
PI3K	-0.001	0.068	-9999.0	0.0	-0.164	77.0	77.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.025	0.011	-9999.0	0.0	0.0	94.0	94.0
somite specification	0.028	0.132	0.301	84.0	-0.393	9.0	93.0
SHH Np/Cholesterol/PTCH1	-0.003	0.114	0.265	75.0	-0.236	20.0	95.0
SHH Np/Cholesterol/PTCH2	-0.032	0.016	0.142	1.0	-0.13	5.0	6.0
SHH Np/Cholesterol/Megalin	-0.025	0.019	-9999.0	0.0	-0.13	4.0	4.0
SHH	-0.03	0.014	0.19	1.0	-9999.0	0.0	1.0
catabolic process	0.022	0.156	0.372	84.0	-0.275	24.0	108.0
SMO/Vitamin D3	0.004	0.121	0.256	76.0	-0.353	10.0	86.0
SHH Np/Cholesterol/Hhip	-0.031	0.016	0.142	1.0	-0.13	5.0	6.0
LRP2	0.022	0.013	-9999.0	0.0	0.0	140.0	140.0
receptor-mediated endocytosis	0.026	0.125	0.276	76.0	-0.403	8.0	84.0
SHH Np/Cholesterol/BOC	-0.04	0.033	0.142	1.0	-0.13	55.0	56.0
SHH Np/Cholesterol/CDO	-0.032	0.018	0.142	1.0	-0.13	7.0	8.0
mesenchymal cell differentiation	0.031	0.016	0.13	5.0	-0.14	1.0	6.0
mol:Vitamin D3	0.004	0.117	0.235	101.0	-0.268	8.0	109.0
IHH N/PTCH2	0.05	0.041	0.179	4.0	-9999.0	0.0	4.0
CDON	0.028	0.007	-9999.0	0.0	0.0	32.0	32.0
IHH N/PTCH1	-0.034	0.054	-9999.0	0.0	-0.277	24.0	24.0
Megalin/LRPAP1	0.031	0.023	-9999.0	0.0	-0.164	2.0	2.0
PTCH2	0.029	0.006	-9999.0	0.0	0.0	20.0	20.0
SHH Np/Cholesterol	-0.022	0.014	0.155	1.0	-0.119	5.0	6.0
PTCH1	0.022	0.157	0.373	84.0	-0.276	24.0	108.0
HHIP	0.028	0.006	-9999.0	0.0	0.0	26.0	26.0