Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 18 (10%) 166 0.42637 1 0.38256 1 0.01718 1 0.0076199 1 0.76125 1 0.7375 1 1 1 0.93779 1 0.13432 1 0.89365 1 1q gain 50 (27%) 134 0.0078999 1 0.00162 1 0.23548 1 0.36638 1 0.01262 1 0.061949 1 0.0055099 1 0.0387 1 0.00032 0.235 0.01141 1 2p gain 14 (8%) 170 0.02109 1 0.00298 1 0.1007 1 0.59208 1 0.63554 1 0.18772 1 0.43561 1 0.01513 1 0.12922 1 0.099809 1 2q gain 16 (9%) 168 0.03569 1 0.0090799 1 0.1003 1 0.59368 1 0.46629 1 0.18254 1 0.51616 1 0.00476 1 0.2006 1 0.03999 1 3p gain 10 (5%) 174 0.01335 1 0.18838 1 0.26546 1 0.68452 1 0.54174 1 0.61785 1 0.83973 1 0.4424 1 0.53027 1 0.52679 1 3q gain 20 (11%) 164 0.00049 0.356 0.00225 1 0.33346 1 0.16057 1 0.2657 1 0.27816 1 0.77264 1 0.059019 1 0.17511 1 0.26506 1 4p gain 11 (6%) 173 0.01538 1 0.78344 1 0.85935 1 0.23951 1 0.00148 1 0.0096699 1 0.0354 1 0.02108 1 0.78011 1 0.20844 1 4q gain 8 (4%) 176 0.00071999 0.515 0.41115 1 0.86137 1 0.23886 1 0.02208 1 0.03407 1 0.02169 1 0.04041 1 0.52084 1 0.15448 1 5p gain 28 (15%) 156 9.9999e-06 0.00782 0.77648 1 0.60037 1 0.37027 1 0.66779 1 0.15681 1 0.24146 1 0.12431 1 0.0063899 1 0.4566 1 5q gain 20 (11%) 164 9.9999e-06 0.00782 0.6001 1 0.71063 1 0.22005 1 0.32515 1 0.01031 1 0.10951 1 0.03395 1 0.11517 1 0.14533 1 6p gain 7 (4%) 177 0.00041 0.3 0.67939 1 0.49435 1 0.48629 1 0.88731 1 1 1 0.9073 1 0.87536 1 0.059179 1 1 1 6q gain 5 (3%) 179 0.0165 1 0.44139 1 NA NA NA NA 0.8514 1 1 1 1 1 1 1 0.03113 1 0.45277 1 7p gain 52 (28%) 132 9.9999e-06 0.00782 0.01039 1 0.071779 1 0.29166 1 0.35291 1 0.26811 1 0.27608 1 0.04722 1 0.0054699 1 0.16396 1 7q gain 48 (26%) 136 9.9999e-06 0.00782 0.055329 1 0.2129 1 0.67298 1 0.75788 1 0.25937 1 0.66895 1 0.34004 1 0.02241 1 0.45109 1 8p gain 26 (14%) 158 0.00364 1 0.04213 1 0.55795 1 0.49185 1 0.75796 1 0.958 1 0.22156 1 0.55226 1 0.01282 1 0.66243 1 8q gain 48 (26%) 136 5.9999e-05 0.0447 0.00071999 0.515 0.46855 1 0.49283 1 0.29431 1 0.54373 1 0.39589 1 0.079319 1 0.00104 0.734 0.067609 1 9p gain 8 (4%) 176 0.01169 1 1 1 0.5948 1 0.52181 1 0.591 1 0.63485 1 0.6835 1 0.78709 1 0.57677 1 0.44659 1 9q gain 12 (7%) 172 6.9999e-05 0.052 0.6711 1 0.7663 1 0.68369 1 0.92625 1 0.61187 1 0.6283 1 0.26337 1 0.26335 1 0.28007 1 10p gain 10 (5%) 174 0.03626 1 0.13008 1 0.01393 1 0.12402 1 0.21389 1 0.81483 1 0.47408 1 0.90021 1 0.00069999 0.501 1 1 10q gain 13 (7%) 171 0.02638 1 0.04994 1 0.02794 1 0.079549 1 0.14765 1 0.38104 1 0.29719 1 0.91397 1 0.00037 0.271 1 1 11p gain 13 (7%) 171 0.00071999 0.515 0.04854 1 0.04526 1 0.67353 1 0.75489 1 1 1 0.72515 1 0.79215 1 0.43175 1 0.75098 1 11q gain 15 (8%) 169 0.0061599 1 0.061189 1 0.01657 1 0.20482 1 0.9389 1 0.93725 1 0.50249 1 0.53484 1 0.28409 1 0.18039 1 12p gain 30 (16%) 154 9.9999e-06 0.00782 0.0064499 1 0.3209 1 0.25145 1 0.67699 1 0.25537 1 0.11031 1 0.069349 1 0.0022 1 0.45717 1 12q gain 22 (12%) 162 9.9999e-06 0.00782 0.02271 1 0.35294 1 0.30617 1 0.58596 1 0.11105 1 0.20735 1 0.04054 1 0.00403 1 0.15637 1 13q gain 29 (16%) 155 0.01655 1 0.60161 1 0.34972 1 0.65631 1 0.21123 1 0.47181 1 0.21736 1 0.12371 1 0.43068 1 0.79466 1 14q gain 26 (14%) 158 9.9999e-06 0.00782 0.33033 1 0.58476 1 0.89368 1 0.27573 1 0.57564 1 0.16892 1 0.26713 1 0.1033 1 0.92478 1 15q gain 14 (8%) 170 0.089869 1 0.10765 1 0.14198 1 0.59622 1 0.34286 1 0.13132 1 0.24709 1 1 1 0.25469 1 0.86596 1 16p gain 22 (12%) 162 2e-05 0.0151 0.0042 1 0.01648 1 0.24982 1 0.15275 1 0.058529 1 0.066829 1 0.01451 1 0.00205 1 0.02888 1 16q gain 23 (12%) 161 9.9999e-06 0.00782 0.0076599 1 0.26048 1 0.52821 1 0.10572 1 0.055729 1 0.01307 1 0.00075999 0.54 0.00269 1 0.00322 1 17p gain 9 (5%) 175 4e-05 0.0299 0.0394 1 0.8916 1 0.4951 1 0.0027 1 0.00057999 0.419 0.00084999 0.602 0.00252 1 0.22511 1 0.01001 1 17q gain 17 (9%) 167 0.00046 0.335 0.38848 1 0.97119 1 0.83169 1 0.19105 1 0.062009 1 0.094459 1 0.070649 1 0.11947 1 0.24474 1 18p gain 28 (15%) 156 9.9999e-06 0.00782 0.04487 1 0.21128 1 0.053229 1 0.02682 1 0.1973 1 0.14667 1 0.02184 1 0.03366 1 0.10245 1 18q gain 12 (7%) 172 5e-05 0.0373 0.60133 1 0.6408 1 0.04207 1 0.38028 1 0.49145 1 0.47913 1 0.12409 1 0.3632 1 0.088379 1 19p gain 17 (9%) 167 0.00068999 0.495 0.14344 1 0.47148 1 0.29683 1 0.68377 1 0.62184 1 0.01247 1 0.33671 1 0.38412 1 0.59447 1 19q gain 28 (15%) 156 0.00036 0.264 0.17731 1 0.61228 1 0.52143 1 0.89583 1 0.89079 1 0.068119 1 0.68617 1 0.10733 1 1 1 20p gain 34 (18%) 150 9.9999e-06 0.00782 0.21747 1 0.1353 1 0.45468 1 0.22656 1 0.15412 1 0.21915 1 0.01624 1 0.0064299 1 0.25677 1 20q gain 45 (24%) 139 9.9999e-06 0.00782 0.12638 1 0.41194 1 0.33259 1 0.54485 1 0.17548 1 0.3311 1 0.02338 1 0.00051999 0.376 0.20788 1 22q gain 8 (4%) 176 0.34795 1 0.054189 1 0.2637 1 0.40012 1 0.10567 1 0.079579 1 0.36723 1 0.064919 1 0.14385 1 0.27004 1 xq gain 13 (7%) 171 0.00027 0.199 1 1 0.69886 1 0.4068 1 0.12563 1 0.0093199 1 0.15973 1 0.03675 1 0.81267 1 0.087119 1 1p loss 36 (20%) 148 5.9999e-05 0.0447 0.00433 1 0.00045 0.328 0.00161 1 0.01032 1 0.064219 1 0.16607 1 0.051079 1 0.02855 1 0.02401 1 1q loss 8 (4%) 176 0.04236 1 0.28429 1 0.51647 1 0.7001 1 1 1 0.50859 1 0.76018 1 0.69537 1 0.10255 1 0.78197 1 2p loss 11 (6%) 173 0.0079099 1 0.57305 1 1 1 0.95341 1 0.67087 1 0.19143 1 0.91977 1 0.75931 1 0.26452 1 0.84702 1 2q loss 5 (3%) 179 0.00049 0.356 0.60214 1 NA NA NA NA 0.45122 1 0.090159 1 0.44787 1 0.29528 1 0.15913 1 0.36193 1 3p loss 36 (20%) 148 0.00184 1 0.25603 1 0.19526 1 0.11792 1 0.64971 1 0.9056 1 0.20808 1 0.30093 1 0.10662 1 0.55559 1 3q loss 19 (10%) 165 0.03095 1 0.17277 1 0.0073799 1 0.0056499 1 0.52939 1 0.67199 1 0.78709 1 1 1 0.0074699 1 0.85217 1 4p loss 25 (14%) 159 0.04075 1 0.03143 1 0.40331 1 0.52592 1 0.10498 1 0.10339 1 0.57794 1 0.01158 1 0.95801 1 0.00331 1 4q loss 25 (14%) 159 0.24427 1 0.04918 1 0.5054 1 0.41687 1 0.054359 1 0.18326 1 0.19941 1 0.00273 1 0.70617 1 0.00111 0.781 5p loss 9 (5%) 175 0.00361 1 0.17547 1 0.516 1 0.7001 1 0.91088 1 0.23695 1 0.84118 1 1 1 0.16036 1 0.80386 1 5q loss 13 (7%) 171 0.00381 1 0.0025 1 0.23497 1 0.57577 1 0.9345 1 0.25144 1 0.62159 1 0.44835 1 0.13858 1 0.60065 1 6p loss 64 (35%) 120 9.9999e-06 0.00782 3e-05 0.0225 0.071639 1 0.38809 1 0.13533 1 0.01419 1 0.22095 1 0.00101 0.714 0.00266 1 0.00013 0.0965 6q loss 83 (45%) 101 9.9999e-06 0.00782 2e-05 0.0151 0.0083199 1 0.069749 1 0.00031 0.228 0.00048 0.349 0.00139 0.972 2e-05 0.0151 9.9999e-06 0.00782 2e-05 0.0151 7p loss 3 (2%) 181 0.17791 1 0.31977 1 NA NA NA NA 0.7984 1 0.77364 1 0.42751 1 1 1 0.42958 1 0.31389 1 7q loss 4 (2%) 180 0.070739 1 0.18763 1 0.45462 1 0.41383 1 0.81038 1 1 1 0.53927 1 1 1 0.26442 1 0.56054 1 8p loss 41 (22%) 143 0.00114 0.8 0.01678 1 0.24901 1 0.15507 1 0.14758 1 0.00496 1 0.01527 1 0.01248 1 0.0066699 1 0.00233 1 8q loss 16 (9%) 168 0.01922 1 0.52195 1 0.25066 1 0.22961 1 0.79322 1 0.43697 1 0.33414 1 0.45569 1 0.050119 1 0.16906 1 9p loss 75 (41%) 109 9.9999e-06 0.00782 0.12997 1 0.0087899 1 0.071329 1 0.00287 1 0.03858 1 0.01705 1 0.0145 1 0.0084299 1 0.0073799 1 9q loss 43 (23%) 141 0.11513 1 0.96704 1 0.30251 1 0.38707 1 0.2682 1 0.44122 1 0.19572 1 0.26625 1 0.21896 1 0.31 1 10p loss 36 (20%) 148 0.00024 0.177 0.15757 1 0.4541 1 0.58843 1 0.15965 1 0.1933 1 0.36884 1 0.14802 1 0.063599 1 0.095859 1 10q loss 30 (16%) 154 0.00017 0.126 0.61691 1 0.77116 1 0.71224 1 0.18427 1 0.01695 1 0.53002 1 0.33534 1 0.22753 1 0.098209 1 11p loss 17 (9%) 167 0.00141 0.984 0.04167 1 0.34163 1 0.068939 1 0.9434 1 0.68286 1 0.47602 1 0.48123 1 0.47367 1 0.7282 1 11q loss 16 (9%) 168 0.00065999 0.475 0.45184 1 0.16248 1 0.01384 1 0.78725 1 0.81766 1 0.92979 1 0.5738 1 0.4009 1 0.81995 1 12p loss 20 (11%) 164 0.00018 0.133 0.00078999 0.561 0.00044 0.321 0.00254 1 0.061249 1 0.0086899 1 0.084129 1 0.00108 0.761 0.34298 1 0.00174 1 12q loss 28 (15%) 156 9.9999e-06 0.00782 0.04348 1 0.00191 1 0.00335 1 0.15184 1 0.00285 1 0.12353 1 0.11675 1 0.24148 1 0.02375 1 13q loss 20 (11%) 164 0.00060999 0.44 0.01348 1 0.82894 1 0.83187 1 0.00296 1 0.15546 1 0.0234 1 0.01354 1 0.00179 1 0.061889 1 14q loss 16 (9%) 168 0.23414 1 0.18601 1 0.085689 1 0.1585 1 0.4957 1 0.074199 1 0.37468 1 0.2176 1 0.77096 1 0.57791 1 15q loss 30 (16%) 154 4e-05 0.0299 0.00065999 0.475 0.29481 1 0.55236 1 0.02062 1 0.00212 1 0.079149 1 0.0063299 1 0.10526 1 0.0037 1 16p loss 11 (6%) 173 0.0079099 1 0.28169 1 0.01219 1 0.17418 1 0.67176 1 0.48968 1 0.63145 1 0.42534 1 0.27888 1 0.83727 1 16q loss 13 (7%) 171 0.02439 1 0.10832 1 0.49566 1 0.48791 1 0.7065 1 0.12254 1 0.43003 1 0.2444 1 0.13268 1 0.28304 1 17p loss 80 (43%) 104 9.9999e-06 0.00782 9.9999e-06 0.00782 0.00302 1 0.0062799 1 9.9999e-06 0.00782 9.9999e-06 0.00782 9.9999e-06 0.00782 2e-05 0.0151 9.9999e-06 0.00782 3e-05 0.0225 17q loss 22 (12%) 162 0.00064999 0.468 0.00499 1 0.02226 1 0.24255 1 0.15584 1 0.38881 1 0.51719 1 0.31257 1 0.17821 1 0.31562 1 18p loss 55 (30%) 129 0.12899 1 0.097179 1 0.84698 1 0.442 1 0.6451 1 0.63385 1 0.36286 1 0.90349 1 0.26941 1 0.2742 1 18q loss 106 (58%) 78 9.9999e-06 0.00782 0.00079999 0.567 0.01625 1 0.0085099 1 0.00239 1 0.0052299 1 0.01488 1 0.00344 1 0.04735 1 2e-05 0.0151 19p loss 19 (10%) 165 0.00128 0.896 0.00112 0.787 0.35395 1 0.77913 1 0.062909 1 0.02412 1 0.39014 1 0.0063799 1 2e-04 0.148 0.01949 1 19q loss 12 (7%) 172 0.0069499 1 0.061929 1 0.00481 1 0.29652 1 0.03996 1 0.01497 1 0.48598 1 0.050979 1 0.099429 1 0.074529 1 20p loss 20 (11%) 164 0.00033 0.242 0.0095199 1 0.7282 1 0.67233 1 0.0069399 1 0.091529 1 0.03673 1 0.04117 1 0.00214 1 0.01452 1 20q loss 5 (3%) 179 0.27014 1 0.078309 1 NA NA NA NA 0.38076 1 0.84798 1 0.92049 1 0.82597 1 0.12998 1 0.60267 1 21q loss 58 (32%) 126 9.9999e-06 0.00782 0.00074999 0.534 0.18021 1 0.12215 1 0.02187 1 0.095989 1 0.38862 1 0.03255 1 0.00059999 0.433 0.03625 1 22q loss 46 (25%) 138 9.9999e-06 0.00782 0.01732 1 0.97374 1 0.98931 1 0.21779 1 0.37538 1 0.31053 1 0.03943 1 0.00116 0.813 0.02819 1 xq loss 18 (10%) 166 9.9999e-06 0.00782 0.03365 1 0.33951 1 0.19791 1 0.36928 1 0.32796 1 0.26652 1 0.8345 1 0.49135 1 0.58289 1