Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.078 0.162 0.286 63.0 -9999.0 0.0 63.0 KIRREL -0.022 0.11 -9999.0 0.0 -0.388 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 PLCG1 0.036 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.031 0.033 -9999.0 0.0 -0.372 1.0 1.0 WASL 0.036 0.008 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.146 -9999.0 0.0 -0.234 40.0 40.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.07 0.136 -9999.0 0.0 -0.246 52.0 52.0 FYN -0.055 0.128 0.264 3.0 -0.212 62.0 65.0 mol:Ca2+ -0.043 0.144 -9999.0 0.0 -0.367 8.0 8.0 mol:DAG -0.042 0.145 -9999.0 0.0 -0.368 8.0 8.0 NPHS2 -0.027 0.104 -9999.0 0.0 -0.385 12.0 12.0 mol:IP3 -0.042 0.145 -9999.0 0.0 -0.368 8.0 8.0 regulation of endocytosis -0.043 0.128 -9999.0 0.0 -0.201 60.0 60.0 Nephrin/NEPH1/podocin/Cholesterol -0.054 0.137 -9999.0 0.0 -0.214 70.0 70.0 establishment of cell polarity -0.078 0.162 -9999.0 0.0 -0.286 63.0 63.0 Nephrin/NEPH1/podocin/NCK1-2 -0.027 0.145 -9999.0 0.0 -0.341 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 -0.042 0.13 -9999.0 0.0 -0.203 60.0 60.0 NPHS1 -0.107 0.191 -9999.0 0.0 -0.381 57.0 57.0 Nephrin/NEPH1/podocin -0.051 0.133 -9999.0 0.0 -0.212 64.0 64.0 TJP1 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.037 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.038 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.146 -9999.0 0.0 -0.37 8.0 8.0 CD2AP 0.037 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.045 0.143 -9999.0 0.0 -0.218 61.0 61.0 GRB2 0.035 0.011 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.059 0.123 0.284 3.0 -0.341 10.0 13.0 cytoskeleton organization -0.092 0.149 -9999.0 0.0 -0.291 52.0 52.0 Nephrin/NEPH1 -0.048 0.115 -9999.0 0.0 -0.195 63.0 63.0 Nephrin/NEPH1/ZO-1 -0.045 0.14 -9999.0 0.0 -0.225 61.0 61.0