Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.049 0.138 0.359 29.0 -9999.0 0.0 29.0 KIRREL -0.076 0.199 -9999.0 0.0 -0.529 29.0 29.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.049 0.138 -9999.0 0.0 -0.36 29.0 29.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.028 0.103 -9999.0 0.0 -0.259 29.0 29.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.017 0.1 -9999.0 0.0 -0.255 22.0 22.0 FYN -0.021 0.104 -9999.0 0.0 -0.248 29.0 29.0 mol:Ca2+ -0.028 0.102 -9999.0 0.0 -0.257 29.0 29.0 mol:DAG -0.028 0.103 -9999.0 0.0 -0.258 29.0 29.0 NPHS2 -0.003 0.02 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.028 0.103 -9999.0 0.0 -0.258 29.0 29.0 regulation of endocytosis -0.023 0.093 -9999.0 0.0 -0.231 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol -0.033 0.102 -9999.0 0.0 -0.262 29.0 29.0 establishment of cell polarity -0.049 0.138 -9999.0 0.0 -0.359 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 -0.02 0.095 -9999.0 0.0 -0.255 22.0 22.0 Nephrin/NEPH1/beta Arrestin2 -0.023 0.094 -9999.0 0.0 -0.233 29.0 29.0 NPHS1 0.001 0.018 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.03 0.098 -9999.0 0.0 -0.249 29.0 29.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.028 0.103 -9999.0 0.0 -0.259 29.0 29.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.028 0.103 -9999.0 0.0 -0.283 22.0 22.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.019 0.1 -9999.0 0.0 -0.24 27.0 27.0 cytoskeleton organization -0.019 0.112 -9999.0 0.0 -0.285 22.0 22.0 Nephrin/NEPH1 -0.032 0.097 -9999.0 0.0 -0.25 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.032 0.111 -9999.0 0.0 -0.282 29.0 29.0