Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1q22 40 (8%) 452 9.9999e-06 0.00648 0.00044 0.2 0.00162 0.674 0.02075 1 0.00098999 0.431 0.00176 0.723 0.0129 1 4e-04 0.183 0.03943 1 0.01912 1 amp_3q21.3 75 (15%) 417 9.9999e-06 0.00648 6.9999e-05 0.0349 0.17356 1 0.20082 1 0.00311 1 0.0057399 1 0.0173 1 0.00041 0.187 0.0093099 1 0.00025 0.117 amp_3q26.2 86 (17%) 406 9.9999e-06 0.00648 0.092889 1 0.15093 1 0.39819 1 0.01307 1 0.051229 1 0.082109 1 0.0077899 1 0.0074199 1 2e-05 0.0105 amp_4p16.3 20 (4%) 472 9.9999e-06 0.00648 0.03936 1 0.50726 1 0.28435 1 0.01597 1 0.076699 1 0.40797 1 0.073169 1 0.74588 1 0.58441 1 amp_4q13.3 22 (4%) 470 9.9999e-06 0.00648 0.38992 1 0.4707 1 0.78087 1 0.2012 1 0.25499 1 0.02693 1 0.066549 1 0.03635 1 0.16423 1 amp_5q35.3 28 (6%) 464 9.9999e-06 0.00648 0.02355 1 0.11109 1 0.19324 1 0.067229 1 0.070219 1 0.18344 1 0.00091999 0.402 0.01675 1 0.29625 1 amp_7p14.3 104 (21%) 388 9.9999e-06 0.00648 9.9999e-06 0.00648 0.35532 1 0.56426 1 9.9999e-06 0.00648 0.00039 0.179 0.00363 1 0.00058999 0.263 0.00111 0.476 0.0087599 1 amp_7q22.1 101 (21%) 391 9.9999e-06 0.00648 9.9999e-06 0.00648 0.4089 1 0.58322 1 9.9999e-06 0.00648 8.9999e-05 0.0441 0.0058199 1 9.9999e-06 0.00648 0.00045 0.203 0.00363 1 amp_8p11.23 67 (14%) 425 9.9999e-06 0.00648 9.9999e-06 0.00648 0.096709 1 0.16197 1 7.9999e-05 0.0395 0.01898 1 0.046 1 0.0013 0.549 9.9999e-06 0.00648 0.00053999 0.242 amp_8q22.1 157 (32%) 335 9.9999e-06 0.00648 9.9999e-06 0.00648 0.0061799 1 0.0066099 1 8.9999e-05 0.0441 0.01728 1 3e-05 0.0153 9.9999e-06 0.00648 9.9999e-06 0.00648 6.9999e-05 0.0349 amp_8q24.21 152 (31%) 340 9.9999e-06 0.00648 9.9999e-06 0.00648 0.0061699 1 0.0064999 1 2e-05 0.0105 0.00118 0.503 9.9999e-06 0.00648 9.9999e-06 0.00648 9.9999e-06 0.00648 0.00044 0.2 amp_9q33.3 62 (13%) 430 9.9999e-06 0.00648 0.00252 1 0.057239 1 0.04304 1 0.00386 1 0.00219 0.88 0.01884 1 0.00095999 0.419 0.0168 1 0.0084199 1 amp_11q13.2 48 (10%) 444 9.9999e-06 0.00648 0.02667 1 0.52193 1 0.52421 1 0.02828 1 0.00075999 0.337 0.03213 1 0.00018 0.0855 0.0071299 1 0.02959 1 amp_12q23.1 36 (7%) 456 2e-05 0.0105 7.9999e-05 0.0395 0.057089 1 0.11062 1 0.16081 1 0.02041 1 0.65043 1 0.00214 0.867 0.28841 1 0.1237 1 amp_13q12.11 25 (5%) 467 9.9999e-06 0.00648 0.01287 1 0.04259 1 0.03326 1 0.0065699 1 0.12544 1 0.01463 1 0.03226 1 0.067019 1 0.073909 1 amp_14q21.1 30 (6%) 462 9.9999e-06 0.00648 0.12677 1 0.16719 1 0.17956 1 0.093469 1 0.055369 1 0.0081499 1 0.01076 1 0.067829 1 0.02877 1 amp_15q11.2 16 (3%) 476 0.0096499 1 0.068699 1 0.78485 1 0.78065 1 0.94819 1 0.56295 1 0.13257 1 0.68477 1 0.53207 1 0.15434 1 amp_16q11.2 30 (6%) 462 9.9999e-06 0.00648 0.00090999 0.399 1 1 1 1 0.17881 1 0.01518 1 0.0017 0.704 0.00109 0.469 0.081619 1 0.24225 1 amp_17q23.2 25 (5%) 467 9.9999e-06 0.00648 0.00299 1 1 1 0.32139 1 0.082839 1 0.21828 1 0.5209 1 0.01407 1 0.37875 1 0.089939 1 amp_19q13.43 19 (4%) 473 9.9999e-06 0.00648 0.13439 1 0.44951 1 0.3864 1 0.17999 1 0.16626 1 0.0063099 1 0.00139 0.584 0.15227 1 0.0118 1 amp_20q13.2 45 (9%) 447 9.9999e-06 0.00648 2e-05 0.0105 0.30511 1 0.32735 1 0.0127 1 0.01347 1 0.00044 0.2 5.9999e-05 0.03 0.16018 1 6.9999e-05 0.0349 amp_xp22.11 26 (5%) 466 9.9999e-06 0.00648 0.23612 1 NA NA NA NA 0.093889 1 0.097239 1 0.01545 1 0.0050799 1 0.04496 1 0.31127 1 amp_xp22.11 25 (5%) 467 2e-05 0.0105 0.25279 1 0.093809 1 0.18638 1 0.03881 1 0.01152 1 0.0078999 1 0.0098599 1 0.04644 1 0.23448 1 amp_xp21.1 23 (5%) 469 2e-05 0.0105 0.0073199 1 0.85006 1 0.73605 1 0.067199 1 0.068239 1 0.02015 1 0.0091399 1 0.0052499 1 0.14641 1 amp_xq21.1 16 (3%) 476 0.00088999 0.391 0.18157 1 0.48427 1 0.64088 1 0.01147 1 0.065659 1 0.31258 1 0.45418 1 0.45032 1 0.39292 1 amp_xq21.1 14 (3%) 478 0.00252 1 0.18412 1 0.44863 1 1 1 0.082649 1 0.0118 1 0.052129 1 0.23616 1 0.30103 1 0.77723 1 amp_xq25 19 (4%) 473 0.00263 1 0.00325 1 1 1 0.87844 1 0.13825 1 0.02524 1 0.20348 1 0.15142 1 0.72953 1 0.14281 1 amp_xq27.1 19 (4%) 473 0.00424 1 0.070639 1 0.41837 1 0.21693 1 0.13129 1 0.26251 1 0.00103 0.446 0.00013 0.0628 0.03599 1 0.12563 1 del_1p31.3 60 (12%) 432 9.9999e-06 0.00648 9.9999e-06 0.00648 0.33645 1 0.52792 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.00181 0.738 0.16633 1 0.0055099 1 0.00124 0.525 del_1p22.1 58 (12%) 434 9.9999e-06 0.00648 7.9999e-05 0.0395 0.23023 1 0.093319 1 0.00336 1 0.03504 1 0.0079399 1 0.00308 1 0.01014 1 0.0072199 1 del_1q23.1 28 (6%) 464 0.0050199 1 0.00082999 0.366 0.24082 1 0.28612 1 0.00131 0.552 0.03402 1 0.04486 1 0.053599 1 0.02031 1 0.18794 1 del_1q42.3 47 (10%) 445 0.00108 0.465 6.9999e-05 0.0349 0.93283 1 0.10606 1 0.10673 1 0.45611 1 0.11071 1 0.03199 1 0.6977 1 0.04725 1 del_2p21 46 (9%) 446 9.9999e-06 0.00648 0.00022 0.103 0.14354 1 0.5816 1 2e-04 0.0948 0.0097499 1 0.00065999 0.294 0.072489 1 0.03321 1 0.01452 1 del_2q22.1 92 (19%) 400 9.9999e-06 0.00648 9.9999e-06 0.00648 0.02467 1 0.062739 1 9.9999e-06 0.00648 0.00027 0.125 2e-05 0.0105 9.9999e-06 0.00648 0.00173 0.714 0.00115 0.491 del_2q22.3 85 (17%) 407 9.9999e-06 0.00648 9.9999e-06 0.00648 0.24447 1 0.086679 1 4e-05 0.0202 0.0018 0.738 0.00026 0.121 9.9999e-06 0.00648 0.01311 1 2e-04 0.0948 del_3p13 78 (16%) 414 5e-04 0.224 9.9999e-06 0.00648 0.83994 1 0.91939 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.29267 1 0.064339 1 0.02932 1 0.16835 1 del_3q29 32 (7%) 460 0.61178 1 0.20741 1 0.72807 1 0.13718 1 0.063819 1 0.00334 1 0.31234 1 0.25191 1 0.11928 1 0.60058 1 del_4q28.2 51 (10%) 441 9.9999e-06 0.00648 9.9999e-06 0.00648 0.090539 1 0.097449 1 2e-05 0.0105 0.03584 1 0.092099 1 0.0151 1 0.00105 0.454 0.02459 1 del_5q11.2 100 (20%) 392 9.9999e-06 0.00648 9.9999e-06 0.00648 0.00441 1 0.0314 1 0.0062099 1 0.00371 1 9.9999e-05 0.0488 9.9999e-06 0.00648 0.00113 0.484 0.00021 0.0989 del_5q13.2 99 (20%) 393 9.9999e-06 0.00648 4e-05 0.0202 0.02122 1 0.18286 1 0.0156 1 0.14415 1 0.00025 0.117 9.9999e-06 0.00648 0.00214 0.867 0.00027 0.125 del_5q21.1 109 (22%) 383 9.9999e-06 0.00648 9.9999e-06 0.00648 0.11985 1 0.096069 1 9.9999e-06 0.00648 2e-05 0.0105 0.00029 0.134 0.00295 1 0.099919 1 0.00483 1 del_6p25.1 46 (9%) 446 9.9999e-06 0.00648 0.01196 1 0.69638 1 0.93239 1 0.0080299 1 0.00158 0.659 0.14814 1 0.04912 1 0.38737 1 0.01654 1 del_6q14.3 180 (37%) 312 9.9999e-06 0.00648 9.9999e-06 0.00648 0.0074699 1 0.00242 0.97 9.9999e-06 0.00648 9.9999e-06 0.00648 9.9999e-06 0.00648 5e-05 0.0251 0.0018 0.738 0.00493 1 del_7q31.33 28 (6%) 464 0.00014 0.0672 0.03608 1 0.0281 1 0.0145 1 0.00013 0.0628 0.061949 1 0.00099999 0.434 0.00021 0.0989 0.75193 1 0.04787 1 del_8p23.2 224 (46%) 268 9.9999e-06 0.00648 9.9999e-06 0.00648 0.0061199 1 0.050979 1 9.9999e-06 0.00648 0.00011 0.0535 2e-04 0.0948 0.00041 0.187 0.0348 1 0.00146 0.612 del_8p21.3 294 (60%) 198 9.9999e-06 0.00648 9.9999e-06 0.00648 0.03092 1 0.051079 1 9.9999e-06 0.00648 2e-05 0.0105 3e-05 0.0153 9.9999e-06 0.00648 0.0091999 1 9.9999e-06 0.00648 del_9p23 45 (9%) 447 9.9999e-06 0.00648 0.086119 1 0.00331 1 0.03045 1 0.00016 0.0765 0.01227 1 0.02715 1 0.081529 1 0.075499 1 0.01662 1 del_10q23.31 157 (32%) 335 9.9999e-06 0.00648 9.9999e-06 0.00648 0.066749 1 0.14249 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.01407 1 9.9999e-06 0.00648 0.03912 1 9.9999e-06 0.00648 del_11p11.2 34 (7%) 458 9.9999e-06 0.00648 0.060259 1 0.04105 1 0.33909 1 0.00045 0.203 0.086569 1 0.03056 1 0.02397 1 0.0078899 1 0.475 1 del_11q22.3 43 (9%) 449 0.04353 1 0.01005 1 0.16344 1 0.37785 1 0.2928 1 0.03454 1 0.86235 1 0.78083 1 0.15645 1 0.01229 1 del_11q23.2 48 (10%) 444 0.13272 1 0.19232 1 0.2341 1 0.15897 1 0.81049 1 0.89331 1 0.23263 1 0.46491 1 0.30388 1 0.25868 1 del_12p13.1 124 (25%) 368 9.9999e-06 0.00648 3e-05 0.0153 0.059429 1 0.079559 1 0.00083999 0.37 0.00364 1 0.063249 1 3e-05 0.0153 6.9999e-05 0.0349 0.00295 1 del_12q24.32 43 (9%) 449 5e-05 0.0251 0.3126 1 1 1 0.82907 1 0.21491 1 0.19398 1 0.63003 1 0.54943 1 0.39199 1 0.072879 1 del_13q14.13 227 (46%) 265 9.9999e-06 0.00648 9.9999e-06 0.00648 0.077449 1 0.22269 1 2e-05 0.0105 0.00267 1 0.00011 0.0535 4e-04 0.183 0.00016 0.0765 7.9999e-05 0.0395 del_13q22.1 176 (36%) 316 9.9999e-06 0.00648 0.00065999 0.294 0.0089199 1 0.03987 1 4e-05 0.0202 0.00254 1 0.00497 1 0.00123 0.523 0.00175 0.721 0.00011 0.0535 del_15q21.3 67 (14%) 425 9.9999e-06 0.00648 9.9999e-05 0.0488 0.00194 0.788 0.0069099 1 9.9999e-06 0.00648 0.00016 0.0765 9.9999e-06 0.00648 5e-05 0.0251 0.00013 0.0628 9.9999e-06 0.00648 del_16q22.3 191 (39%) 301 9.9999e-06 0.00648 9.9999e-06 0.00648 0.42277 1 0.21795 1 9.9999e-06 0.00648 9.9999e-06 0.00648 3e-05 0.0153 9.9999e-06 0.00648 9.9999e-06 0.00648 9.9999e-06 0.00648 del_16q24.1 213 (43%) 279 9.9999e-06 0.00648 9.9999e-06 0.00648 0.67935 1 0.49517 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.00028 0.129 9.9999e-06 0.00648 0.00262 1 9.9999e-06 0.00648 del_17p13.1 163 (33%) 329 9.9999e-06 0.00648 9.9999e-06 0.00648 0.03208 1 0.04915 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.00015 0.0718 9.9999e-06 0.00648 0.00151 0.631 9.9999e-06 0.00648 del_17q21.31 96 (20%) 396 9.9999e-06 0.00648 9.9999e-06 0.00648 0.52317 1 0.7488 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.55499 1 0.054339 1 0.17126 1 0.31278 1 del_18q21.31 131 (27%) 361 9.9999e-06 0.00648 0.00191 0.777 0.28601 1 0.21771 1 0.00162 0.674 0.067279 1 0.00021 0.0989 0.01782 1 0.0035 1 9.9999e-06 0.00648 del_18q23 137 (28%) 355 9.9999e-06 0.00648 0.01598 1 0.92022 1 0.3075 1 0.00031 0.143 0.02252 1 0.01102 1 0.0072899 1 0.0093399 1 9.9999e-06 0.00648 del_19q13.2 52 (11%) 440 9.9999e-06 0.00648 0.072279 1 0.35467 1 0.35793 1 0.0051499 1 0.04398 1 0.00274 1 0.00075999 0.337 0.00218 0.879 0.00123 0.523 del_21q22.2 52 (11%) 440 0.00055999 0.25 0.00351 1 0.41981 1 0.76533 1 2e-05 0.0105 9.9999e-06 0.00648 0.16531 1 0.0406 1 0.83315 1 0.00322 1 del_21q22.3 147 (30%) 345 9.9999e-06 0.00648 9.9999e-06 0.00648 0.078059 1 0.36748 1 9.9999e-06 0.00648 9.9999e-06 0.00648 0.03214 1 2e-05 0.0105 0.76994 1 9.9999e-06 0.00648