Clinical feature	Statistical test	Significant variables	Associated with	               	Associated with	
AGE	Spearman correlation test	N=2	older	N=2	younger	N=0
AGE_mutation rate	Linear Regression Analysis	N=0	 	 	 	 
PATHOLOGY T STAGE	Spearman correlation test	N=1	higher stage	N=1	lower stage	N=0
PATHOLOGY N STAGE	Wilcoxon test	N=0	 	 	 	 
HISTOLOGICAL TYPE	Wilcoxon test	N=1	prostate adenocarcinoma acinar type	N=1	prostate adenocarcinoma  other subtype	N=0
COMPLETENESS OF RESECTION	Kruskal-Wallis test	N=0	 	 	 	 
NUMBER OF LYMPH NODES	Spearman correlation test	N=0	 	 	 	 
GLEASON_SCORE_COMBINED	Spearman correlation test	N=2	higher score	N=2	lower score	N=0
GLEASON_SCORE_PRIMARY	Spearman correlation test	N=2	higher score	N=2	lower score	N=0
GLEASON_SCORE_SECONDARY	Spearman correlation test	N=0	 	 	 	 
GLEASON_SCORE	Spearman correlation test	N=2	higher score	N=2	lower score	N=0
PSA_RESULT_PREOP	Spearman correlation test	N=2	higher psa_result_preop	N=2	lower psa_result_preop	N=0
PSA_VALUE	Spearman correlation test	N=2	higher psa_value	N=2	lower psa_value	N=0
RACE	Kruskal-Wallis test	N=0