Ephrin B reverse signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations EFNB2 -0.006 0.105 -9999.0 0.0 -0.576 16.0 16.0 EPHB2 0.005 0.064 -9999.0 0.0 -0.518 7.0 7.0 EFNB1 0.015 0.044 -9999.0 0.0 -0.346 7.0 7.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Rac1/GDP -0.042 0.133 -9999.0 0.0 -0.569 9.0 9.0 Ephrin B2/EPHB1-2 -0.074 0.149 -9999.0 0.0 -0.269 165.0 165.0 neuron projection morphogenesis -0.067 0.11 -9999.0 0.0 -0.543 9.0 9.0 Ephrin B1/EPHB1-2/Tiam1 -0.051 0.142 -9999.0 0.0 -0.532 12.0 12.0 DNM1 0.011 0.035 -9999.0 0.0 -0.525 2.0 2.0 cell-cell signaling -0.0 0.001 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K4 0.015 0.039 -9999.0 0.0 -0.567 2.0 2.0 YES1 -0.002 0.05 -9999.0 0.0 -0.784 2.0 2.0 Ephrin B1/EPHB1-2/NCK2 -0.049 0.135 -9999.0 0.0 -0.477 12.0 12.0 PI3K 0.015 0.061 -9999.0 0.0 -0.609 3.0 3.0 mol:GDP -0.051 0.14 -9999.0 0.0 -0.524 12.0 12.0 ITGA2B -0.003 0.091 -9999.0 0.0 -0.513 15.0 15.0 endothelial cell proliferation 0.005 0.066 -9999.0 0.0 -0.355 16.0 16.0 FYN -0.002 0.05 -9999.0 0.0 -0.784 2.0 2.0 MAP3K7 0.009 0.041 -9999.0 0.0 -0.606 2.0 2.0 FGR -0.002 0.052 -9999.0 0.0 -0.79 2.0 2.0 TIAM1 0.01 0.038 -9999.0 0.0 -0.471 3.0 3.0 PIK3R1 0.008 0.049 -9999.0 0.0 -0.471 5.0 5.0 RGS3 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 cell adhesion -0.028 0.127 -9999.0 0.0 -0.536 11.0 11.0 LYN -0.002 0.05 -9999.0 0.0 -0.784 2.0 2.0 Ephrin B1/EPHB1-2/Src Family Kinases -0.004 0.048 -9999.0 0.0 -0.752 2.0 2.0 Ephrin B1/EPHB1-2 -0.005 0.042 -9999.0 0.0 -0.659 2.0 2.0 SRC -0.001 0.051 -9999.0 0.0 -0.79 2.0 2.0 ITGB3 -0.083 0.193 -9999.0 0.0 -0.471 97.0 97.0 EPHB1 -0.142 0.226 -9999.0 0.0 -0.472 155.0 155.0 EPHB4 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAC1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Ephrin B2/EPHB4 0.006 0.067 -9999.0 0.0 -0.356 16.0 16.0 alphaIIb/beta3 Integrin -0.061 0.154 -9999.0 0.0 -0.343 108.0 108.0 BLK -0.03 0.076 -9999.0 0.0 -0.791 2.0 2.0 HCK -0.002 0.053 -9999.0 0.0 -0.791 2.0 2.0 regulation of stress fiber formation 0.049 0.133 0.471 12.0 -9999.0 0.0 12.0 MAPK8 0.016 0.055 -9999.0 0.0 -0.644 2.0 2.0 Ephrin B1/EPHB1-2/RGS3 -0.049 0.135 -9999.0 0.0 -0.477 12.0 12.0 endothelial cell migration 0.004 0.065 -9999.0 0.0 -0.317 18.0 18.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PTPN13 0.012 0.039 -9999.0 0.0 -0.586 2.0 2.0 regulation of focal adhesion formation 0.049 0.133 0.471 12.0 -9999.0 0.0 12.0 chemotaxis 0.049 0.133 0.471 12.0 -9999.0 0.0 12.0 PIK3CA 0.01 0.038 -9999.0 0.0 -0.471 3.0 3.0 Rac1/GTP -0.067 0.115 -9999.0 0.0 -0.561 9.0 9.0 angiogenesis -0.005 0.042 -9999.0 0.0 -0.655 2.0 2.0 LCK -0.002 0.051 -9999.0 0.0 -0.79 2.0 2.0