Lissencephaly gene (LIS1) in neuronal migration and development Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations DYNC1H1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 VLDLR 0.012 0.022 -9999.0 0.0 -0.471 1.0 1.0 LRPAP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NUDC 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RELN/LRP8 -0.038 0.146 -9999.0 0.0 -0.355 83.0 83.0 CaM/Ca2+ 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 KATNA1 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 GO:0030286 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ABL1 -0.028 0.133 -9999.0 0.0 -0.32 78.0 78.0 IQGAP1/CaM 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 DAB1 -0.174 0.235 -9999.0 0.0 -0.472 187.0 187.0 IQGAP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G7 -0.137 0.256 -9999.0 0.0 -0.574 124.0 124.0 CALM1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 DYNLT1 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 mol:Ca2+ -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 LRPAP1/LRP8 0.013 0.052 -9999.0 0.0 -0.416 7.0 7.0 UniProt:Q4QZ09 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CLIP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R1 -0.016 0.128 -9999.0 0.0 -0.576 24.0 24.0 LIS1/Poliovirus Protein 3A 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R2 -0.053 0.185 -9999.0 0.0 -0.576 54.0 54.0 mol:PP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1 -0.145 0.204 -9999.0 0.0 -0.345 224.0 224.0 YWHAE 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1/14-3-3 E -0.022 0.131 -9999.0 0.0 -0.41 20.0 20.0 MAP1B -0.022 0.074 -9999.0 0.0 -0.271 40.0 40.0 RAC1 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 p35/CDK5 -0.026 0.143 -9999.0 0.0 -0.613 9.0 9.0 RELN -0.081 0.215 -9999.0 0.0 -0.569 79.0 79.0 PAFAH/LIS1 -0.069 0.162 -9999.0 0.0 -0.347 124.0 124.0 LIS1/CLIP170 0.025 0.0 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/NDEL1/Katanin 60/Dynein Light chain/Dynein heavy chain -0.045 0.084 -9999.0 0.0 -0.438 3.0 3.0 RELN/VLDLR/DAB1/LIS1/PAFAH1B2/PAFAH1B3 -0.102 0.165 -9999.0 0.0 -0.44 58.0 58.0 GO:0005869 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1 -0.031 0.137 -9999.0 0.0 -0.437 21.0 21.0 LIS1/IQGAP1 0.025 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RHOA 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B1 0.021 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B3 -0.01 0.113 -9999.0 0.0 -0.57 19.0 19.0 PAFAH1B2 -0.002 0.084 -9999.0 0.0 -0.471 15.0 15.0 MAP1B/LIS1/Dynein heavy chain 0.009 0.051 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1/Katanin 60/Dynein heavy chain -0.015 0.127 -9999.0 0.0 -0.392 20.0 20.0 LRP8 0.005 0.07 -9999.0 0.0 -0.576 7.0 7.0 NDEL1/Katanin 60 -0.022 0.131 -9999.0 0.0 -0.406 21.0 21.0 P39/CDK5 -0.046 0.155 -9999.0 0.0 -0.548 15.0 15.0 LIS1/NudC/Dynein intermediate chain/microtubule organizing center 0.025 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CDK5 -0.02 0.124 -9999.0 0.0 -0.576 3.0 3.0 PPP2R5D 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/CLIP170/Dynein Complex/Dynactin Complex 0.022 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CSNK2A1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1/LIS1 -0.11 0.179 -9999.0 0.0 -0.519 43.0 43.0 RELN/VLDLR -0.026 0.135 -9999.0 0.0 -0.322 78.0 78.0 CDC42 0.02 0.0 -9999.0 0.0 -9999.0 0.0 0.0