Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.067 0.152 0.348 109.0 -9999.0 0.0 109.0 KIRREL -0.087 0.196 -9999.0 0.0 -0.475 99.0 99.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.068 0.153 -9999.0 0.0 -0.349 109.0 109.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.115 -9999.0 0.0 -0.536 2.0 2.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.029 0.105 -9999.0 0.0 -0.418 3.0 3.0 FYN -0.041 0.108 -9999.0 0.0 -0.294 13.0 13.0 mol:Ca2+ -0.04 0.114 -9999.0 0.0 -0.323 14.0 14.0 mol:DAG -0.04 0.115 -9999.0 0.0 -0.324 14.0 14.0 NPHS2 -0.011 0.05 -9999.0 0.0 -0.586 3.0 3.0 mol:IP3 -0.04 0.115 -9999.0 0.0 -0.324 14.0 14.0 regulation of endocytosis -0.031 0.103 -9999.0 0.0 -0.473 2.0 2.0 Nephrin/NEPH1/podocin/Cholesterol -0.048 0.115 -9999.0 0.0 -0.256 109.0 109.0 establishment of cell polarity -0.067 0.152 -9999.0 0.0 -0.348 109.0 109.0 Nephrin/NEPH1/podocin/NCK1-2 -0.028 0.108 -9999.0 0.0 -0.503 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 -0.03 0.104 -9999.0 0.0 -0.479 2.0 2.0 NPHS1 -0.016 0.087 -9999.0 0.0 -0.574 11.0 11.0 Nephrin/NEPH1/podocin -0.041 0.109 -9999.0 0.0 -0.293 14.0 14.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.027 -9999.0 0.0 -0.576 1.0 1.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.115 -9999.0 0.0 -0.326 14.0 14.0 CD2AP 0.013 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.115 -9999.0 0.0 -0.326 14.0 14.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.079 0.158 -9999.0 0.0 -0.345 96.0 96.0 cytoskeleton organization -0.029 0.115 -9999.0 0.0 -0.459 3.0 3.0 Nephrin/NEPH1 -0.045 0.107 -9999.0 0.0 -0.242 109.0 109.0 Nephrin/NEPH1/ZO-1 -0.043 0.122 -9999.0 0.0 -0.341 12.0 12.0