Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.047 0.183 0.255 1.0 -0.379 87.0 88.0 MAP3K8 0.018 0.053 0.166 1.0 -0.31 12.0 13.0 FOS -0.038 0.144 0.238 2.0 -0.369 52.0 54.0 PRKCA 0.006 0.068 -9999.0 0.0 -0.31 20.0 20.0 PTPN7 0.024 0.037 0.165 21.0 -9999.0 0.0 21.0 HRAS 0.028 0.015 0.165 5.0 -9999.0 0.0 5.0 PRKCB -0.051 0.138 -9999.0 0.0 -0.311 105.0 105.0 NRAS 0.026 0.016 -9999.0 0.0 -0.318 1.0 1.0 RAS family/GTP 0.041 0.028 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.01 0.092 -9999.0 0.0 -0.406 6.0 6.0 MAP2K1 -0.079 0.202 -9999.0 0.0 -0.424 103.0 103.0 ELK1 0.018 0.023 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.063 0.176 -9999.0 0.0 -0.4 88.0 88.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 82.0 82.0 MAPK1 -0.015 0.109 -9999.0 0.0 -0.427 15.0 15.0 RAF1 -0.069 0.179 -9999.0 0.0 -0.388 99.0 99.0 KRAS 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0