Clinical feature	Statistical test	Significant variables	Associated with	               	Associated with	
Time to Death	Cox regression test	N=0	 	 	 	 
AGE	Spearman correlation test	N=0	 	 	 	 
AGE_mutation rate	Linear Regression Analysis	N=2	 	 	 	 
NEOPLASM DISEASESTAGE	Kruskal-Wallis test	N=0	 	 	 	 
PATHOLOGY T STAGE	Spearman correlation test	N=0	 	 	 	 
PATHOLOGY N STAGE	Spearman correlation test	N=0	 	 	 	 
PATHOLOGY M STAGE	Wilcoxon test	N=0	 	 	 	 
GENDER	Wilcoxon test	N=0	 	 	 	 
HISTOLOGICAL TYPE	Wilcoxon test	N=2	rectal mucinous adenocarcinoma	N=2	rectal adenocarcinoma	N=0
COMPLETENESS OF RESECTION	Kruskal-Wallis test	N=0	 	 	 	 
NUMBER OF LYMPH NODES	Spearman correlation test	N=0