Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q APC 56 (81%) 13 0.92304 1 0.91462 1 0.4982 1 0.36077 1 0.38141 1 0.24319 1 1 1 0.45846 1 0.62749 1 TP53 44 (64%) 25 0.00014 0.014 0.01483 1 0.12662 1 0.16056 1 0.843 1 0.48845 1 0.6538 1 1 1 0.14628 1 KRAS 38 (55%) 31 0.24847 1 0.0076199 0.739 0.0072199 0.708 0.83099 1 0.85418 1 0.04592 1 0.00013 0.0131 0.29191 1 0.0061499 0.609 SMAD4 8 (12%) 61 0.079039 1 0.77926 1 1 1 0.15239 1 0.055619 1 0.18795 1 0.22893 1 0.30925 1 0.26362 1 FBXW7 9 (13%) 60 0.19247 1 0.4101 1 0.41017 1 0.69 1 0.63208 1 1 1 0.11749 1 0.80445 1 0.57629 1 NRAS 5 (7%) 64 1 1 0.84053 1 0.73661 1 NA NA NA NA 1 1 1 1 0.097299 1 1 1 ARID1A 5 (7%) 64 0.36353 1 0.39231 1 0.91732 1 0.17334 1 0.53149 1 1 1 1 1 0.314 1 0.25833 1 RBM10 4 (6%) 65 1 1 0.78828 1 1 1 1 1 0.77932 1 0.01609 1 0.0438 1 0.53205 1 0.56707 1 TCF7L2 7 (10%) 62 0.78157 1 0.20757 1 1 1 0.15255 1 0.29242 1 1 1 0.30488 1 1 1 0.68699 1 ERBB2 4 (6%) 65 1 1 0.87524 1 1 1 0.67335 1 0.4086 1 0.03238 1 0.03312 1 1 1 1 1 KIAA1804 9 (13%) 60 0.50968 1 0.83523 1 0.0305 1 1 1 0.5959 1 1 1 0.76087 1 0.80594 1 0.5755 1 CCDC88C 3 (4%) 66 NA NA NA NA NA NA NA NA NA NA 1 1 0.59563 1 0.43239 1 0.46337 1