Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.139 0.581 9.0 -9999.0 0.0 9.0 KIRREL 0.008 0.018 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.139 -9999.0 0.0 -0.583 9.0 9.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.015 0.134 -9999.0 0.0 -0.472 12.0 12.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.086 -9999.0 0.0 -0.501 2.0 2.0 FYN -0.018 0.119 -9999.0 0.0 -0.423 12.0 12.0 mol:Ca2+ -0.014 0.132 -9999.0 0.0 -0.467 12.0 12.0 mol:DAG -0.014 0.133 -9999.0 0.0 -0.469 12.0 12.0 NPHS2 -0.017 0.122 -9999.0 0.0 -0.777 4.0 4.0 mol:IP3 -0.014 0.133 -9999.0 0.0 -0.469 12.0 12.0 regulation of endocytosis -0.007 0.114 -9999.0 0.0 -0.396 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.021 0.133 -9999.0 0.0 -0.476 12.0 12.0 establishment of cell polarity -0.021 0.139 -9999.0 0.0 -0.581 9.0 9.0 Nephrin/NEPH1/podocin/NCK1-2 -0.005 0.125 -9999.0 0.0 -0.433 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.006 0.116 -9999.0 0.0 -0.401 12.0 12.0 NPHS1 -0.032 0.176 -9999.0 0.0 -0.761 9.0 9.0 Nephrin/NEPH1/podocin -0.015 0.121 -9999.0 0.0 -0.425 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.013 0.134 -9999.0 0.0 -0.472 12.0 12.0 CD2AP 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.013 0.134 -9999.0 0.0 -0.472 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.017 0.123 -9999.0 0.0 -0.434 12.0 12.0 cytoskeleton organization -0.004 0.107 -9999.0 0.0 -0.59 2.0 2.0 Nephrin/NEPH1 -0.014 0.103 -9999.0 0.0 -0.431 9.0 9.0 Nephrin/NEPH1/ZO-1 -0.008 0.116 -9999.0 0.0 -0.476 9.0 9.0