Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.299 0.312 0.637 116.0 -9999.0 0.0 116.0 KIRREL -0.049 0.084 -9999.0 0.0 -0.354 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.3 0.313 -9999.0 0.0 -0.639 116.0 116.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.273 0.295 -9999.0 0.0 -0.545 126.0 126.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.21 0.23 -9999.0 0.0 -0.424 126.0 126.0 FYN -0.258 0.28 -9999.0 0.0 -0.516 126.0 126.0 mol:Ca2+ -0.27 0.291 -9999.0 0.0 -0.539 126.0 126.0 mol:DAG -0.271 0.293 -9999.0 0.0 -0.542 126.0 126.0 NPHS2 -0.126 0.264 -9999.0 0.0 -0.847 30.0 30.0 mol:IP3 -0.271 0.293 -9999.0 0.0 -0.542 126.0 126.0 regulation of endocytosis -0.241 0.262 -9999.0 0.0 -0.482 126.0 126.0 Nephrin/NEPH1/podocin/Cholesterol -0.277 0.298 -9999.0 0.0 -0.553 126.0 126.0 establishment of cell polarity -0.299 0.312 -9999.0 0.0 -0.637 116.0 116.0 Nephrin/NEPH1/podocin/NCK1-2 -0.25 0.274 -9999.0 0.0 -0.501 126.0 126.0 Nephrin/NEPH1/beta Arrestin2 -0.245 0.267 -9999.0 0.0 -0.49 126.0 126.0 NPHS1 -0.369 0.401 -9999.0 0.0 -0.811 116.0 116.0 Nephrin/NEPH1/podocin -0.26 0.282 -9999.0 0.0 -0.52 126.0 126.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.273 0.295 -9999.0 0.0 -0.545 126.0 126.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.273 0.295 -9999.0 0.0 -0.545 126.0 126.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.258 0.275 -9999.0 0.0 -0.506 128.0 128.0 cytoskeleton organization -0.274 0.301 -9999.0 0.0 -0.554 126.0 126.0 Nephrin/NEPH1 -0.224 0.236 -9999.0 0.0 -0.48 116.0 116.0 Nephrin/NEPH1/ZO-1 -0.245 0.258 -9999.0 0.0 -0.524 116.0 116.0