Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.042	0.167	0.391	1.0	-0.575	5.0	6.0
IHH	-0.096	0.247	0.245	1.0	-0.583	51.0	52.0
SHH Np/Cholesterol/GAS1	-0.055	0.111	-9999.0	0.0	-0.32	37.0	37.0
LRPAP1	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.055	0.11	0.318	37.0	-9999.0	0.0	37.0
SMO/beta Arrestin2	-0.08	0.196	0.318	1.0	-0.42	51.0	52.0
SMO	-0.09	0.197	-9999.0	0.0	-0.437	51.0	51.0
AKT1	-0.038	0.121	-9999.0	0.0	-0.49	7.0	7.0
ARRB2	0.018	0.005	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.019	0.06	0.255	5.0	-0.548	2.0	7.0
ADRBK1	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.09	0.195	-9999.0	0.0	-0.43	52.0	52.0
STIL	-0.064	0.169	0.28	8.0	-0.48	11.0	19.0
DHH N/PTCH2	0.014	0.1	-9999.0	0.0	-0.406	12.0	12.0
DHH N/PTCH1	-0.05	0.17	0.332	1.0	-0.33	60.0	61.0
PIK3CA	0.019	0.003	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.003	0.12	0.255	4.0	-0.548	11.0	15.0
PTHLH	-0.073	0.231	0.483	1.0	-1.05	5.0	6.0
determination of left/right symmetry	-0.09	0.195	-9999.0	0.0	-0.43	52.0	52.0
PIK3R1	0.02	0.015	0.255	1.0	-9999.0	0.0	1.0
skeletal system development	-0.072	0.229	0.482	1.0	-1.033	5.0	6.0
IHH N/Hhip	-0.117	0.239	0.23	13.0	-0.434	85.0	98.0
DHH N/Hhip	-0.059	0.191	0.19	14.0	-0.415	54.0	68.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.09	0.195	-9999.0	0.0	-0.43	52.0	52.0
pancreas development	-0.074	0.227	0.255	14.0	-0.547	45.0	59.0
HHAT	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PI3K	0.028	0.017	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.019	0.041	0.255	2.0	-0.548	1.0	3.0
somite specification	-0.09	0.195	-9999.0	0.0	-0.43	52.0	52.0
SHH Np/Cholesterol/PTCH1	-0.082	0.17	0.325	1.0	-0.361	35.0	36.0
SHH Np/Cholesterol/PTCH2	-0.05	0.118	0.275	1.0	-0.32	37.0	38.0
SHH Np/Cholesterol/Megalin	-0.192	0.181	-9999.0	0.0	-0.352	132.0	132.0
SHH	-0.07	0.138	-9999.0	0.0	-0.407	36.0	36.0
catabolic process	-0.048	0.168	0.287	9.0	-0.344	54.0	63.0
SMO/Vitamin D3	-0.103	0.192	0.385	2.0	-0.393	53.0	55.0
SHH Np/Cholesterol/Hhip	-0.1	0.17	0.169	12.0	-0.35	72.0	84.0
LRP2	-0.249	0.273	-9999.0	0.0	-0.548	115.0	115.0
receptor-mediated endocytosis	-0.212	0.216	0.279	1.0	-0.555	50.0	51.0
SHH Np/Cholesterol/BOC	-0.055	0.114	0.161	2.0	-0.318	38.0	40.0
SHH Np/Cholesterol/CDO	-0.053	0.111	0.161	1.0	-0.319	36.0	37.0
mesenchymal cell differentiation	0.099	0.169	0.348	72.0	-0.167	12.0	84.0
mol:Vitamin D3	-0.086	0.172	0.333	3.0	-0.518	11.0	14.0
IHH N/PTCH2	-0.045	0.171	0.26	6.0	-0.369	51.0	57.0
CDON	0.022	0.03	0.255	4.0	-9999.0	0.0	4.0
IHH N/PTCH1	-0.043	0.171	0.358	1.0	-0.347	54.0	55.0
Megalin/LRPAP1	-0.168	0.213	-9999.0	0.0	-0.406	112.0	112.0
PTCH2	0.026	0.059	0.255	10.0	-0.548	1.0	11.0
SHH Np/Cholesterol	-0.053	0.107	-9999.0	0.0	-0.315	36.0	36.0
PTCH1	-0.048	0.169	0.287	9.0	-0.345	54.0	63.0
HHIP	-0.074	0.228	0.255	14.0	-0.548	45.0	59.0