Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.029	0.104	-9999.0	0.0	-0.206	92.0	92.0
epithelial cell differentiation	-0.004	0.122	-9999.0	0.0	-0.21	91.0	91.0
CYFIP2	0.015	0.09	-9999.0	0.0	-0.417	15.0	15.0
ENAH	-0.032	0.076	0.27	3.0	-0.261	1.0	4.0
EGFR	0.027	0.035	-9999.0	0.0	-0.417	2.0	2.0
EPHA2	0.03	0.047	-9999.0	0.0	-0.417	4.0	4.0
MYO6	-0.033	0.102	0.198	10.0	-0.202	91.0	101.0
CTNNB1	0.035	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.05	0.066	-9999.0	0.0	-0.244	15.0	15.0
AQP5	-0.029	0.089	-9999.0	0.0	-0.324	3.0	3.0
CTNND1	0.035	0.005	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	-0.03	0.101	0.194	10.0	-0.2	89.0	99.0
regulation of calcium-dependent cell-cell adhesion	-0.037	0.106	0.194	10.0	-0.204	97.0	107.0
EGF	0.001	0.114	-9999.0	0.0	-0.417	25.0	25.0
NCKAP1	0.035	0.003	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	-0.078	0.16	0.395	1.0	-0.405	51.0	52.0
cortical microtubule organization	-0.004	0.122	-9999.0	0.0	-0.21	91.0	91.0
GO:0000145	-0.046	0.089	0.182	10.0	-0.191	89.0	99.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.001	0.126	-9999.0	0.0	-0.212	91.0	91.0
MLLT4	0.029	0.014	-9999.0	0.0	-9999.0	0.0	0.0
ARF6/GDP	-0.051	0.074	-9999.0	0.0	-0.188	77.0	77.0
ARF6	0.035	0.005	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.073	0.044	-9999.0	0.0	-0.227	3.0	3.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.031	0.088	0.227	4.0	-0.24	3.0	7.0
PVRL2	0.035	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	-0.028	0.098	0.197	9.0	-0.203	81.0	90.0
ARF6/GTP	0.08	0.047	-9999.0	0.0	-0.212	3.0	3.0
CDH1	-0.08	0.195	-9999.0	0.0	-0.417	92.0	92.0
EGFR/EGFR/EGF/EGF	-0.026	0.124	-9999.0	0.0	-0.214	103.0	103.0
RhoA/GDP	0.0	0.119	-9999.0	0.0	-0.201	91.0	91.0
actin cytoskeleton organization	-0.039	0.098	0.183	10.0	-0.2	91.0	101.0
IGF-1R heterotetramer	0.034	0.006	-9999.0	0.0	-9999.0	0.0	0.0
GIT1	0.034	0.006	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.034	0.006	-9999.0	0.0	-9999.0	0.0	0.0
IGF1	0.03	0.041	-9999.0	0.0	-0.417	3.0	3.0
DIAPH1	-0.017	0.219	-9999.0	0.0	-0.584	30.0	30.0
Wnt receptor signaling pathway	0.004	0.122	0.21	91.0	-9999.0	0.0	91.0
RHOA	0.035	0.005	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	-0.051	0.074	-9999.0	0.0	-0.19	77.0	77.0
CTNNA1	0.033	0.008	-9999.0	0.0	-9999.0	0.0	0.0
VCL	-0.04	0.099	0.184	10.0	-0.204	91.0	101.0
EFNA1	0.032	0.011	-9999.0	0.0	-9999.0	0.0	0.0
LPP	-0.049	0.09	0.193	9.0	-0.196	87.0	96.0
Ephrin A1/EPHA2	-0.006	0.109	-9999.0	0.0	-0.201	81.0	81.0
SEC6/SEC8	-0.032	0.083	-9999.0	0.0	-0.19	77.0	77.0
MGAT3	-0.038	0.107	0.196	10.0	-0.206	97.0	107.0
HGF/MET	-0.019	0.126	-9999.0	0.0	-0.222	93.0	93.0
HGF	0.024	0.058	-9999.0	0.0	-0.417	6.0	6.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.03	0.105	-9999.0	0.0	-0.207	92.0	92.0
actin cable formation	0.004	0.108	0.261	22.0	-0.259	7.0	29.0
KIAA1543	-0.055	0.096	0.184	10.0	-0.197	102.0	112.0
KIFC3	-0.033	0.102	0.209	7.0	-0.203	91.0	98.0
NCK1	0.034	0.006	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.032	0.01	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	-0.032	0.104	0.196	11.0	-0.203	92.0	103.0
NCK1/GIT1	0.049	0.013	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	-0.004	0.122	-9999.0	0.0	-0.21	91.0	91.0
EXOC4	0.031	0.012	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.032	0.104	0.196	11.0	-0.203	91.0	102.0
PIP5K1C	-0.031	0.103	0.196	10.0	-0.203	89.0	99.0
LIMA1	0.035	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ABI1	0.032	0.01	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	-0.025	0.104	0.331	7.0	-0.302	1.0	8.0
adherens junction assembly	-0.041	0.102	0.301	3.0	-0.366	6.0	9.0
IGF-1R heterotetramer/IGF1	-0.007	0.114	-9999.0	0.0	-0.198	92.0	92.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.041	0.023	-9999.0	0.0	-9999.0	0.0	0.0
MET	0.006	0.103	-9999.0	0.0	-0.417	20.0	20.0
PLEKHA7	-0.04	0.109	0.196	10.0	-0.207	102.0	112.0
mol:GTP	0.071	0.043	-9999.0	0.0	-0.226	3.0	3.0
establishment of epithelial cell apical/basal polarity	-0.013	0.12	0.314	12.0	-9999.0	0.0	12.0
cortical actin cytoskeleton stabilization	-0.029	0.104	-9999.0	0.0	-0.206	92.0	92.0
regulation of cell-cell adhesion	-0.039	0.098	0.183	10.0	-0.2	91.0	101.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.03	0.105	-9999.0	0.0	-0.207	92.0	92.0