Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.146 0.199 0.387 148.0 -9999.0 0.0 148.0 KIRREL -0.004 0.047 -9999.0 0.0 -0.54 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.146 0.199 -9999.0 0.0 -0.387 148.0 148.0 PLCG1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.096 0.15 -9999.0 0.0 -0.276 149.0 149.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.084 0.141 -9999.0 0.0 -0.255 148.0 148.0 FYN -0.096 0.14 -9999.0 0.0 -0.265 148.0 148.0 mol:Ca2+ -0.095 0.148 -9999.0 0.0 -0.274 148.0 148.0 mol:DAG -0.095 0.149 -9999.0 0.0 -0.275 148.0 148.0 NPHS2 -0.019 0.026 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.095 0.149 -9999.0 0.0 -0.275 148.0 148.0 regulation of endocytosis -0.079 0.135 -9999.0 0.0 -0.243 148.0 148.0 Nephrin/NEPH1/podocin/Cholesterol -0.105 0.147 -9999.0 0.0 -0.284 148.0 148.0 establishment of cell polarity -0.146 0.199 -9999.0 0.0 -0.387 148.0 148.0 Nephrin/NEPH1/podocin/NCK1-2 -0.076 0.139 -9999.0 0.0 -0.244 148.0 148.0 Nephrin/NEPH1/beta Arrestin2 -0.079 0.137 -9999.0 0.0 -0.246 148.0 148.0 NPHS1 -0.211 0.267 -9999.0 0.0 -0.539 146.0 146.0 Nephrin/NEPH1/podocin -0.096 0.141 -9999.0 0.0 -0.267 148.0 148.0 TJP1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.095 0.15 -9999.0 0.0 -0.276 148.0 148.0 CD2AP 0.017 0.029 -9999.0 0.0 -0.536 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.095 0.15 -9999.0 0.0 -0.276 148.0 148.0 GRB2 0.019 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.098 0.138 -9999.0 0.0 -0.26 148.0 148.0 cytoskeleton organization -0.104 0.171 -9999.0 0.0 -0.311 148.0 148.0 Nephrin/NEPH1 -0.101 0.141 -9999.0 0.0 -0.271 148.0 148.0 Nephrin/NEPH1/ZO-1 -0.104 0.162 -9999.0 0.0 -0.3 148.0 148.0