Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 51 (12%) 390 9.9999e-06 0.0079 0.093399 1 0.00249 1 0.4059 1 0.00155 0.873 0.12377 1 0.00063999 0.379 0.00377 1 0.075329 1 0.063019 1 1q gain 103 (23%) 338 9.9999e-06 0.0079 0.00047 0.283 0.058249 1 0.22154 1 3e-05 0.02 0.00206 1 0.00063999 0.379 3e-05 0.02 0.00359 1 0.29837 1 2p gain 77 (17%) 364 9.9999e-06 0.0079 0.00414 1 0.0214 1 0.11679 1 0.14153 1 0.02845 1 0.00028 0.172 0.0073799 1 0.14181 1 0.02437 1 2q gain 66 (15%) 375 9.9999e-06 0.0079 0.12223 1 0.23741 1 0.55195 1 0.04436 1 0.02981 1 0.00091999 0.537 0.068129 1 0.03308 1 0.28617 1 3p gain 53 (12%) 388 0.00196 1 0.02778 1 0.79128 1 0.02475 1 0.62421 1 0.22579 1 0.18783 1 0.58787 1 0.37321 1 0.03015 1 3q gain 93 (21%) 348 9.9999e-06 0.0079 0.31839 1 0.87522 1 0.15148 1 0.14108 1 0.0204 1 0.055839 1 0.33777 1 0.096549 1 0.01912 1 4p gain 21 (5%) 420 0.078849 1 0.32417 1 0.91179 1 0.27099 1 0.20826 1 0.32133 1 0.51457 1 0.1616 1 0.35023 1 0.23462 1 4q gain 16 (4%) 425 0.4349 1 0.22171 1 0.69114 1 0.088159 1 0.02075 1 0.42874 1 0.49425 1 0.067949 1 0.61363 1 0.66459 1 5p gain 102 (23%) 339 9.9999e-06 0.0079 6.9999e-05 0.0451 0.26219 1 0.96023 1 9.9999e-06 0.0079 0.0053499 1 2e-04 0.124 9.9999e-06 0.0079 0.0086799 1 0.01899 1 5q gain 44 (10%) 397 0.01107 1 0.2479 1 0.85269 1 0.27478 1 0.19607 1 0.36566 1 0.41738 1 0.63973 1 0.14823 1 0.80649 1 6p gain 78 (18%) 363 9.9999e-06 0.0079 9.9999e-06 0.0079 0.10781 1 0.34653 1 0.00062999 0.374 0.0076599 1 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00139 0.791 0.00156 0.877 6q gain 64 (15%) 377 9.9999e-06 0.0079 9.9999e-06 0.0079 0.065269 1 0.34235 1 0.00032 0.195 0.02281 1 6.9999e-05 0.0451 9.9999e-06 0.0079 0.00101 0.586 0.00349 1 7p gain 197 (45%) 244 9.9999e-06 0.0079 0.00198 1 0.67613 1 0.49491 1 0.34097 1 0.00050999 0.305 0.22258 1 0.02798 1 0.36536 1 0.00324 1 7q gain 169 (38%) 272 9.9999e-06 0.0079 0.055079 1 0.92369 1 0.43724 1 0.33782 1 0.00172 0.958 0.31547 1 0.17881 1 0.53974 1 0.04245 1 8p gain 182 (41%) 259 3e-05 0.02 0.01575 1 0.60275 1 0.24077 1 0.44612 1 0.10412 1 0.20545 1 0.4042 1 0.4553 1 0.31803 1 8q gain 237 (54%) 204 0.0090399 1 0.01637 1 0.67633 1 0.29845 1 0.03692 1 0.01706 1 0.04064 1 0.03744 1 0.61884 1 0.37196 1 9p gain 60 (14%) 381 0.095319 1 0.81806 1 0.37686 1 0.85916 1 0.58281 1 0.49514 1 0.69848 1 0.77328 1 0.50041 1 1 1 9q gain 78 (18%) 363 0.21684 1 0.95069 1 0.24957 1 0.98333 1 0.42764 1 0.92652 1 0.97471 1 0.92954 1 0.36267 1 0.77928 1 10p gain 98 (22%) 343 9.9999e-06 0.0079 0.00013 0.082 0.13218 1 0.52994 1 0.00149 0.843 0.14623 1 0.15042 1 0.00345 1 0.22673 1 0.41647 1 10q gain 70 (16%) 371 9.9999e-06 0.0079 0.03935 1 0.12376 1 0.85442 1 0.01303 1 0.12232 1 0.46527 1 0.33704 1 0.67595 1 0.44698 1 11p gain 64 (15%) 377 9.9999e-06 0.0079 0.03703 1 0.93423 1 0.84603 1 0.2845 1 0.39478 1 5.9999e-05 0.0388 0.00154 0.869 0.03946 1 0.12279 1 11q gain 74 (17%) 367 9.9999e-06 0.0079 0.00169 0.943 0.83502 1 1 1 0.31349 1 0.0056999 1 9.9999e-06 0.0079 0.00037 0.224 0.01197 1 0.0091799 1 12p gain 90 (20%) 351 0.00016 0.1 0.17683 1 0.2373 1 0.33697 1 0.16717 1 0.10226 1 0.057849 1 0.17394 1 0.12869 1 0.083609 1 12q gain 77 (17%) 364 0.00363 1 0.95334 1 0.43948 1 0.42462 1 0.96554 1 0.27824 1 0.15674 1 0.38801 1 0.23059 1 0.1087 1 13q gain 154 (35%) 287 9.9999e-06 0.0079 0.00014 0.0881 0.67713 1 0.6084 1 0.02278 1 7.9999e-05 0.051 0.00094999 0.554 0.00012 0.076 0.00134 0.765 0.52872 1 14q gain 29 (7%) 412 6.9999e-05 0.0451 0.084569 1 0.8121 1 0.92865 1 0.1963 1 0.7634 1 0.0076699 1 0.51003 1 0.20459 1 0.5963 1 15q gain 39 (9%) 402 5e-05 0.0327 0.00324 1 0.34684 1 0.82818 1 0.03501 1 0.22649 1 0.11595 1 0.0088499 1 0.59775 1 0.47598 1 16p gain 59 (13%) 382 0.00132 0.755 0.0074999 1 0.39499 1 0.11278 1 0.074779 1 0.28693 1 0.90562 1 0.97673 1 0.24388 1 0.095229 1 16q gain 47 (11%) 394 0.00281 1 0.19708 1 0.67296 1 0.26151 1 0.18608 1 0.62567 1 0.70663 1 0.95882 1 0.050509 1 0.01652 1 17p gain 29 (7%) 412 0.00096999 0.565 0.40392 1 0.66523 1 0.6843 1 0.19144 1 0.21571 1 0.051339 1 0.19412 1 0.10851 1 0.31402 1 17q gain 62 (14%) 379 2e-05 0.0136 0.16471 1 0.94357 1 0.96407 1 0.48727 1 0.20707 1 0.0433 1 0.33801 1 0.072089 1 0.0067099 1 18p gain 84 (19%) 357 9.9999e-06 0.0079 9.9999e-06 0.0079 0.10363 1 0.050499 1 0.0087699 1 0.00151 0.853 0.00024 0.149 2e-05 0.0136 0.00406 1 0.01106 1 18q gain 54 (12%) 387 0.0066599 1 0.00185 1 0.59911 1 0.23674 1 0.28026 1 0.02199 1 0.01546 1 0.02084 1 0.2835 1 0.03785 1 19p gain 54 (12%) 387 6.9999e-05 0.0451 0.93072 1 0.49728 1 0.066269 1 0.48962 1 0.90601 1 0.57517 1 0.46153 1 0.54019 1 0.42569 1 19q gain 78 (18%) 363 9.9999e-06 0.0079 0.54057 1 0.14867 1 0.04315 1 0.01612 1 0.25145 1 0.01629 1 0.057019 1 0.0068099 1 0.087249 1 20p gain 243 (55%) 198 9.9999e-06 0.0079 0.00018 0.112 0.078069 1 0.19438 1 0.00051999 0.311 9.9999e-06 0.0079 9.9999e-06 0.0079 2e-05 0.0136 5e-05 0.0327 0.55353 1 20q gain 279 (63%) 162 9.9999e-06 0.0079 9.9999e-06 0.0079 0.052369 1 0.22838 1 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 2e-05 0.0136 0.11142 1 21q gain 21 (5%) 420 0.00016 0.1 0.00036 0.219 0.1447 1 0.63607 1 0.0099199 1 0.03163 1 0.090989 1 6.9999e-05 0.0451 0.16809 1 0.02967 1 22q gain 32 (7%) 409 0.0022 1 0.13629 1 0.84428 1 0.21736 1 0.25888 1 0.066599 1 0.23386 1 0.62166 1 0.02855 1 0.16976 1 xq gain 54 (12%) 387 9.9999e-06 0.0079 0.00055999 0.333 0.48113 1 0.58488 1 0.03942 1 0.00054999 0.328 0.081549 1 0.10428 1 0.42693 1 0.098279 1 1p loss 59 (13%) 382 9.9999e-06 0.0079 9.9999e-06 0.0079 0.03088 1 0.19068 1 0.071499 1 0.0077999 1 0.0084399 1 0.00421 1 0.0077599 1 0.43224 1 1q loss 28 (6%) 413 3e-05 0.02 9.9999e-06 0.0079 0.03414 1 0.2977 1 0.59252 1 0.15236 1 0.074359 1 0.31385 1 0.52099 1 0.55337 1 2p loss 26 (6%) 415 3e-05 0.02 0.00073999 0.434 0.37748 1 0.4745 1 0.01241 1 0.29434 1 0.04064 1 0.14097 1 0.47026 1 0.33391 1 2q loss 33 (7%) 408 9.9999e-06 0.0079 6.9999e-05 0.0451 0.66545 1 0.80301 1 0.0088599 1 0.26223 1 0.02338 1 0.03273 1 0.60696 1 0.20705 1 3p loss 91 (21%) 350 9.9999e-06 0.0079 0.00346 1 0.358 1 0.19966 1 0.00309 1 0.00026 0.161 0.00163 0.913 0.00106 0.614 0.15731 1 0.02097 1 3q loss 54 (12%) 387 9.9999e-06 0.0079 0.00049 0.294 0.19293 1 0.27701 1 9.9999e-06 0.0079 9.9999e-06 0.0079 0.02751 1 0.01242 1 0.082409 1 0.00134 0.765 4p loss 167 (38%) 274 9.9999e-06 0.0079 7.9999e-05 0.051 0.28743 1 0.13842 1 0.00059999 0.356 0.00017 0.106 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00035 0.213 0.24489 1 4q loss 164 (37%) 277 9.9999e-06 0.0079 5e-05 0.0327 0.080179 1 0.03196 1 0.0059999 1 0.00148 0.839 3e-05 0.02 9.9999e-06 0.0079 0.0055799 1 0.2096 1 5p loss 60 (14%) 381 9.9999e-06 0.0079 0.00043 0.259 0.22072 1 0.75533 1 0.00229 1 0.01241 1 0.00028 0.172 6.9999e-05 0.0451 0.00351 1 0.14976 1 5q loss 106 (24%) 335 9.9999e-06 0.0079 9.9999e-06 0.0079 0.47858 1 0.9528 1 2e-05 0.0136 3e-05 0.02 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00334 1 6p loss 52 (12%) 389 2e-05 0.0136 0.00177 0.982 0.1497 1 0.91202 1 0.02211 1 0.0084799 1 0.091989 1 0.01605 1 0.03249 1 0.45205 1 6q loss 70 (16%) 371 9.9999e-06 0.0079 0.00118 0.68 0.9 1 0.81423 1 0.063269 1 0.14056 1 0.55444 1 0.060299 1 0.109 1 0.44725 1 7p loss 20 (5%) 421 4e-04 0.242 0.02044 1 0.443 1 0.43226 1 0.00165 0.922 0.33907 1 0.00022 0.136 0.02238 1 0.00224 1 0.22039 1 7q loss 30 (7%) 411 9.9999e-06 0.0079 0.0044 1 0.48547 1 0.78104 1 0.0057899 1 0.28108 1 0.0078799 1 0.050389 1 0.04738 1 0.40921 1 8p loss 88 (20%) 353 9.9999e-06 0.0079 0.068889 1 0.39404 1 0.64466 1 0.01717 1 0.00126 0.724 0.00218 1 0.0072099 1 0.01935 1 2e-05 0.0136 8q loss 33 (7%) 408 0.00085999 0.503 0.80768 1 0.82599 1 0.37235 1 0.75394 1 0.98476 1 0.02409 1 0.5083 1 0.03092 1 0.22727 1 9p loss 150 (34%) 291 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00211 1 0.00029 0.177 9.9999e-06 0.0079 0.00026 0.161 2e-05 0.0136 9.9999e-06 0.0079 0.02098 1 0.065769 1 9q loss 104 (24%) 337 9.9999e-06 0.0079 0.00026 0.161 0.20807 1 0.01585 1 4e-05 0.0263 0.0094999 1 9.9999e-06 0.0079 9.9999e-06 0.0079 0.01322 1 0.1925 1 10p loss 64 (15%) 377 9.9999e-06 0.0079 0.0057599 1 0.7089 1 0.094569 1 0.01468 1 0.074629 1 5e-05 0.0327 0.00032 0.195 0.21184 1 0.35253 1 10q loss 67 (15%) 374 9.9999e-06 0.0079 0.00031 0.189 0.6755 1 0.051569 1 0.00187 1 0.00212 1 3e-05 0.02 0.00016 0.1 0.2746 1 0.20536 1 11p loss 62 (14%) 379 9.9999e-06 0.0079 0.01524 1 0.01781 1 0.069979 1 0.16925 1 0.31556 1 0.052239 1 0.01765 1 0.17096 1 0.29404 1 11q loss 61 (14%) 380 4e-05 0.0263 0.16449 1 0.67399 1 0.45264 1 0.62325 1 0.62688 1 0.064849 1 0.37049 1 0.16946 1 0.22662 1 12p loss 63 (14%) 378 9.9999e-06 0.0079 9.9999e-06 0.0079 0.21857 1 0.13671 1 2e-05 0.0136 9.9999e-06 0.0079 7.9999e-05 0.051 2e-05 0.0136 0.096819 1 0.03242 1 12q loss 52 (12%) 389 9.9999e-06 0.0079 9.9999e-06 0.0079 0.27735 1 0.11116 1 0.00053999 0.322 0.00079999 0.469 0.075709 1 0.00098999 0.575 0.371 1 0.19796 1 13q loss 36 (8%) 405 0.00341 1 0.86778 1 0.68693 1 0.30541 1 0.28083 1 0.60284 1 0.70089 1 0.44385 1 0.76215 1 0.14514 1 14q loss 111 (25%) 330 9.9999e-06 0.0079 2e-05 0.0136 0.5602 1 0.53087 1 0.00106 0.614 0.0090099 1 4e-05 0.0263 8.9999e-05 0.0571 0.13854 1 0.058689 1 15q loss 90 (20%) 351 9.9999e-06 0.0079 0.00126 0.724 0.0055199 1 0.52563 1 0.00012 0.076 0.00176 0.979 0.02431 1 0.02014 1 0.15047 1 0.00335 1 16p loss 100 (23%) 341 9.9999e-06 0.0079 5e-05 0.0327 0.7118 1 0.88345 1 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 0.14962 1 16q loss 115 (26%) 326 9.9999e-06 0.0079 9.9999e-06 0.0079 0.03916 1 0.089029 1 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-05 0.0634 0.49371 1 17p loss 164 (37%) 277 9.9999e-06 0.0079 9.9999e-06 0.0079 0.58038 1 0.02718 1 3e-05 0.02 9.9999e-06 0.0079 9.9999e-06 0.0079 2e-05 0.0136 0.11485 1 0.00067999 0.401 17q loss 74 (17%) 367 9.9999e-06 0.0079 2e-05 0.0136 0.26547 1 0.03345 1 0.00285 1 0.0079899 1 0.00042 0.254 2e-04 0.124 0.11258 1 0.63666 1 18p loss 119 (27%) 322 9.9999e-06 0.0079 0.36745 1 0.77344 1 0.65775 1 0.55787 1 0.24878 1 0.04729 1 0.10659 1 0.37042 1 0.27322 1 18q loss 154 (35%) 287 9.9999e-06 0.0079 0.060749 1 0.34132 1 0.81299 1 0.02126 1 0.02536 1 0.00013 0.082 0.00067999 0.401 0.04425 1 0.02276 1 19p loss 115 (26%) 326 9.9999e-06 0.0079 9.9999e-06 0.0079 0.0065599 1 0.10694 1 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 9.9999e-06 0.0079 5.9999e-05 0.0388 0.0069799 1 19q loss 87 (20%) 354 9.9999e-06 0.0079 9.9999e-06 0.0079 0.03005 1 0.20485 1 9.9999e-06 0.0079 5e-05 0.0327 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00026 0.161 0.01287 1 20p loss 22 (5%) 419 0.00262 1 0.00019 0.118 0.81389 1 0.30881 1 0.00049 0.294 0.057359 1 0.18137 1 0.40921 1 0.56176 1 0.66785 1 21q loss 180 (41%) 261 9.9999e-06 0.0079 0.01353 1 0.10107 1 0.2938 1 0.03756 1 0.0016 0.898 0.00070999 0.417 0.0043 1 0.00131 0.751 0.1107 1 22q loss 146 (33%) 295 9.9999e-06 0.0079 9.9999e-06 0.0079 0.01584 1 0.0070999 1 0.00113 0.652 0.00421 1 9.9999e-06 0.0079 9.9999e-06 0.0079 0.00146 0.829 0.089209 1 xq loss 51 (12%) 390 9.9999e-06 0.0079 5e-05 0.0327 0.50444 1 0.11102 1 0.073389 1 0.092899 1 0.070399 1 0.25225 1 0.078139 1 0.063899 1