Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p36.22 66 (15%) 375 9.9999e-06 0.0089 0.03973 1 0.51658 1 0.24403 1 0.00018 0.105 0.11991 1 0.011 1 0.00072999 0.385 0.13304 1 0.0088399 1 amp_1q21.3 160 (36%) 281 9.9999e-06 0.0089 9.9999e-06 0.0089 0.03406 1 0.02784 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00019 0.111 amp_1q42.3 150 (34%) 291 9.9999e-06 0.0089 4e-05 0.0257 0.40232 1 0.095369 1 9.9999e-06 0.0089 4e-05 0.0257 9.9999e-06 0.0089 9.9999e-06 0.0089 3e-05 0.0199 0.16138 1 amp_3q26.2 164 (37%) 277 9.9999e-06 0.0089 0.0083099 1 0.85778 1 0.00407 1 0.39964 1 0.0107 1 0.00426 1 0.01678 1 0.0033 1 0.0139 1 amp_5p15.33 130 (29%) 311 9.9999e-06 0.0089 9.9999e-06 0.0089 0.12667 1 0.98474 1 9.9999e-06 0.0089 2e-05 0.0137 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00026 0.148 0.00068999 0.366 amp_5p13.1 126 (29%) 315 9.9999e-06 0.0089 9.9999e-06 0.0089 0.73617 1 0.8615 1 9.9999e-06 0.0089 0.00061999 0.332 4e-05 0.0257 9.9999e-06 0.0089 0.01636 1 0.03032 1 amp_6p21.1 124 (28%) 317 9.9999e-06 0.0089 9.9999e-06 0.0089 0.34923 1 0.23418 1 8.9999e-05 0.0547 0.00011 0.0664 9.9999e-06 0.0089 9.9999e-06 0.0089 7.9999e-05 0.0491 0.00039 0.216 amp_6q12 88 (20%) 353 9.9999e-06 0.0089 9.9999e-06 0.0089 0.067489 1 0.88055 1 6.9999e-05 0.0433 0.00044 0.241 5e-05 0.0317 9.9999e-06 0.0089 2e-05 0.0137 0.01337 1 amp_6q21 82 (19%) 359 9.9999e-06 0.0089 0.00037 0.206 0.38496 1 0.40426 1 0.00154 0.762 0.00169 0.825 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00018 0.105 0.00074999 0.392 amp_7p22.1 229 (52%) 212 9.9999e-06 0.0089 7.9999e-05 0.0491 0.63801 1 0.83129 1 0.00012 0.0722 9.9999e-06 0.0089 0.0043 1 5e-05 0.0317 0.04338 1 0.00215 1 amp_7p11.2 214 (49%) 227 9.9999e-06 0.0089 0.00073999 0.389 0.90465 1 0.85205 1 0.04243 1 4e-04 0.221 0.03167 1 0.0022 1 0.096849 1 0.00273 1 amp_7q21.2 204 (46%) 237 9.9999e-06 0.0089 0.00263 1 0.21495 1 0.77263 1 0.45755 1 2e-05 0.0137 0.02994 1 0.00161 0.792 0.10147 1 0.0084699 1 amp_7q22.1 202 (46%) 239 9.9999e-06 0.0089 0.01696 1 0.22759 1 0.88662 1 0.76672 1 0.0016 0.789 0.10173 1 0.03007 1 0.14508 1 0.01663 1 amp_8p23.1 177 (40%) 264 9.9999e-06 0.0089 0.00022 0.127 0.58427 1 0.60148 1 0.055329 1 0.01775 1 0.14321 1 0.069189 1 0.11965 1 0.054639 1 amp_8q24.21 309 (70%) 132 9.9999e-06 0.0089 0.00056999 0.306 0.38201 1 0.37811 1 0.0052699 1 0.01076 1 2e-05 0.0137 9.9999e-06 0.0089 0.00076999 0.402 0.00456 1 amp_9p24.1 65 (15%) 376 6.9999e-05 0.0433 0.46154 1 0.61225 1 0.21983 1 0.10974 1 0.0054099 1 0.03303 1 0.32962 1 0.056409 1 0.14272 1 amp_9p13.2 91 (21%) 350 0.00044 0.241 0.58735 1 0.37711 1 0.32769 1 0.01554 1 0.26499 1 0.056999 1 0.2957 1 0.00236 1 0.1831 1 amp_9q34.3 122 (28%) 319 3e-05 0.0199 0.17609 1 0.72113 1 0.47037 1 0.04482 1 0.13794 1 0.01096 1 0.33019 1 0.15359 1 0.27528 1 amp_10p11.22 119 (27%) 322 9.9999e-06 0.0089 3e-05 0.0199 0.1453 1 0.52097 1 0.00136 0.68 0.0088599 1 0.00111 0.566 4e-05 0.0257 0.00281 1 0.01787 1 amp_10q22.2 88 (20%) 353 9.9999e-06 0.0089 0.02331 1 0.01966 1 0.20278 1 0.01624 1 0.02247 1 0.25413 1 0.13763 1 0.27798 1 0.28825 1 amp_10q26.13 88 (20%) 353 9.9999e-06 0.0089 0.00392 1 0.03581 1 0.33065 1 0.0056499 1 0.02996 1 0.19913 1 0.20257 1 0.81964 1 0.58571 1 amp_11p13 88 (20%) 353 9.9999e-06 0.0089 0.01684 1 0.64637 1 0.11815 1 0.00071999 0.38 0.0056699 1 4e-05 0.0257 0.00016 0.0944 0.0328 1 0.50219 1 amp_11p11.2 92 (21%) 349 9.9999e-06 0.0089 0.00029 0.165 0.6924 1 0.16837 1 3e-05 0.0199 0.00046 0.251 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00042 0.231 0.00309 1 amp_11q13.3 115 (26%) 326 9.9999e-06 0.0089 0.0095799 1 0.18894 1 0.63827 1 0.12859 1 0.03713 1 3e-05 0.0199 0.00304 1 0.00157 0.776 0.04724 1 amp_12p12.1 128 (29%) 313 9.9999e-06 0.0089 0.0429 1 0.4286 1 0.34748 1 0.20829 1 0.36698 1 0.03677 1 0.13571 1 0.60879 1 0.04118 1 amp_12q15 109 (25%) 332 9.9999e-06 0.0089 0.50151 1 0.21861 1 0.32794 1 0.27696 1 0.074219 1 0.13583 1 0.17087 1 0.053569 1 0.21768 1 amp_13q12.3 170 (39%) 271 9.9999e-06 0.0089 9.9999e-06 0.0089 0.3267 1 0.15176 1 0.01716 1 3e-05 0.0199 5e-05 0.0317 3e-05 0.0199 0.00022 0.127 0.061659 1 amp_13q22.1 181 (41%) 260 9.9999e-06 0.0089 9.9999e-06 0.0089 0.25486 1 0.72462 1 2e-05 0.0137 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 8.9999e-05 0.0547 0.03445 1 amp_15q26.1 113 (26%) 328 9.9999e-06 0.0089 0.00017 0.0998 0.14959 1 0.23692 1 3e-05 0.0199 3e-05 0.0199 0.00049 0.266 0.00046 0.251 0.0082199 1 0.00118 0.596 amp_17q12 147 (33%) 294 9.9999e-06 0.0089 9.9999e-06 0.0089 0.79245 1 0.03954 1 0.00015 0.0888 0.00024 0.137 9.9999e-06 0.0089 5.9999e-05 0.0374 0.00475 1 3e-04 0.169 amp_18q11.2 140 (32%) 301 9.9999e-06 0.0089 0.00038 0.211 0.29034 1 0.28776 1 0.01487 1 0.00385 1 0.00050999 0.275 0.00114 0.578 0.36808 1 0.31465 1 amp_19p13.2 47 (11%) 394 2e-05 0.0137 0.15209 1 0.90248 1 0.75536 1 0.73503 1 0.16148 1 0.47772 1 0.70258 1 0.10517 1 0.41169 1 amp_19q12 130 (29%) 311 9.9999e-06 0.0089 9.9999e-06 0.0089 0.0062399 1 0.11447 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.04794 1 amp_19q13.32 111 (25%) 330 9.9999e-06 0.0089 0.059139 1 0.38406 1 0.47411 1 0.00142 0.707 0.084479 1 0.00064999 0.346 0.00476 1 0.00227 1 0.0084899 1 amp_20q13.2 293 (66%) 148 9.9999e-06 0.0089 9.9999e-06 0.0089 0.0068099 1 0.01226 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 7.9999e-05 0.0491 0.078059 1 amp_xq27.3 86 (20%) 355 3e-05 0.0199 0.0069499 1 0.37279 1 0.94279 1 0.46738 1 7.9999e-05 0.0491 0.053719 1 0.3884 1 0.050989 1 0.01507 1 del_1p36.11 135 (31%) 306 9.9999e-06 0.0089 9.9999e-06 0.0089 0.1595 1 0.00111 0.566 0.00024 0.137 9.9999e-06 0.0089 2e-05 0.0137 2e-05 0.0137 2e-05 0.0137 0.00367 1 del_1p13.2 94 (21%) 347 9.9999e-06 0.0089 9.9999e-06 0.0089 0.079429 1 0.064959 1 0.00111 0.566 0.00089999 0.468 0.00186 0.898 0.0068899 1 0.13929 1 0.01595 1 del_1q44 30 (7%) 411 0.00054999 0.296 0.00094999 0.489 0.17857 1 0.11149 1 0.36469 1 0.02668 1 0.0050099 1 0.14825 1 0.89884 1 0.01662 1 del_1q44 26 (6%) 415 0.00231 1 0.00044 0.241 0.30981 1 0.37539 1 0.742 1 0.33752 1 0.22034 1 0.74823 1 0.40715 1 0.55454 1 del_2q32.1 64 (15%) 377 0.00029 0.165 0.03326 1 0.49021 1 0.082419 1 0.089879 1 0.24088 1 0.01656 1 0.00062999 0.336 0.21921 1 0.090769 1 del_2q33.3 49 (11%) 392 0.00021 0.121 0.02614 1 0.39855 1 0.64499 1 0.17653 1 0.8066 1 0.088799 1 0.0094699 1 0.15497 1 0.089549 1 del_2q37.2 72 (16%) 369 9.9999e-06 0.0089 9.9999e-06 0.0089 0.32674 1 0.24091 1 0.00255 1 0.1739 1 0.00116 0.587 3e-05 0.0199 0.21714 1 0.01676 1 del_3p26.1 143 (32%) 298 9.9999e-06 0.0089 9.9999e-06 0.0089 0.34236 1 0.19342 1 0.0066899 1 5e-05 0.0317 3e-05 0.0199 9.9999e-06 0.0089 0.00013 0.0779 0.0052399 1 del_3p14.2 158 (36%) 283 9.9999e-06 0.0089 2e-05 0.0137 0.40926 1 0.37442 1 0.00015 0.0888 0.00019 0.111 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00485 1 0.00019 0.111 del_3q26.31 47 (11%) 394 9.9999e-06 0.0089 2e-05 0.0137 0.0367 1 0.04814 1 0.00048 0.261 5e-05 0.0317 5e-05 0.0317 0.0050099 1 0.00416 1 0.076019 1 del_4p16.3 169 (38%) 272 9.9999e-06 0.0089 0.00167 0.818 0.45837 1 0.19886 1 9.9999e-06 0.0089 5.9999e-05 0.0374 2e-05 0.0137 9.9999e-06 0.0089 0.00033 0.185 0.01234 1 del_4q22.1 193 (44%) 248 9.9999e-06 0.0089 0.00016 0.0944 0.10839 1 0.26663 1 0.00265 1 5.9999e-05 0.0374 0.00103 0.527 0.00062999 0.336 0.58208 1 0.11792 1 del_4q34.3 200 (45%) 241 9.9999e-06 0.0089 9.9999e-06 0.0089 0.052249 1 0.0086599 1 3e-05 0.0199 2e-05 0.0137 9.9999e-06 0.0089 9.9999e-06 0.0089 0.01191 1 0.085989 1 del_5q12.1 170 (39%) 271 9.9999e-06 0.0089 9.9999e-06 0.0089 0.2337 1 0.1774 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 2e-05 0.0137 del_5q23.2 158 (36%) 283 9.9999e-06 0.0089 9.9999e-06 0.0089 0.13534 1 0.076269 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 del_6p25.3 115 (26%) 326 9.9999e-06 0.0089 0.00011 0.0664 0.13774 1 0.82266 1 8.9999e-05 0.0547 3e-05 0.0199 5e-05 0.0317 9.9999e-06 0.0089 0.11147 1 0.04663 1 del_6q14.1 89 (20%) 352 9.9999e-06 0.0089 5e-04 0.27 0.21554 1 0.84218 1 0.00053999 0.291 0.00473 1 0.10097 1 0.00096999 0.498 0.10742 1 0.18814 1 del_6q24.3 78 (18%) 363 9.9999e-06 0.0089 2e-04 0.116 0.8162 1 1 1 0.01404 1 0.02282 1 0.24749 1 0.03044 1 0.01457 1 0.058569 1 del_6q26 102 (23%) 339 9.9999e-06 0.0089 0.00295 1 0.79087 1 0.70246 1 0.00089999 0.468 0.00234 1 0.04065 1 0.0073699 1 0.00298 1 0.00188 0.906 del_7q31.1 71 (16%) 370 9.9999e-06 0.0089 9.9999e-06 0.0089 0.71466 1 0.50049 1 0.0088899 1 0.27873 1 0.00073999 0.389 0.068249 1 0.066239 1 0.12606 1 del_7q36.3 98 (22%) 343 9.9999e-06 0.0089 9.9999e-06 0.0089 0.38285 1 0.077919 1 9.9999e-06 0.0089 0.00033 0.185 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00338 1 0.0087099 1 del_8p23.3 126 (29%) 315 9.9999e-06 0.0089 9.9999e-06 0.0089 0.074639 1 0.5923 1 2e-05 0.0137 9.9999e-06 0.0089 2e-05 0.0137 2e-05 0.0137 0.0088699 1 0.00012 0.0722 del_9p23 195 (44%) 246 9.9999e-06 0.0089 2e-05 0.0137 0.02777 1 0.00091999 0.475 9.9999e-06 0.0089 0.00185 0.895 9.9999e-06 0.0089 0.00013 0.0779 0.15072 1 0.00327 1 del_9p21.3 193 (44%) 248 9.9999e-06 0.0089 9.9999e-06 0.0089 5.9999e-05 0.0374 3e-05 0.0199 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.02868 1 0.03069 1 del_9q21.11 114 (26%) 327 9.9999e-06 0.0089 0.00131 0.658 0.1382 1 0.056239 1 0.00148 0.736 0.03631 1 3e-05 0.0199 9.9999e-06 0.0089 0.03789 1 0.10182 1 del_10p12.31 67 (15%) 374 9.9999e-06 0.0089 0.0075999 1 0.20621 1 0.41259 1 0.17286 1 0.49955 1 3e-05 0.0199 0.0017 0.828 0.29273 1 0.20565 1 del_10q22.3 79 (18%) 362 9.9999e-06 0.0089 0.0028 1 0.84682 1 0.087969 1 2e-04 0.116 0.00064999 0.346 4e-05 0.0257 5e-05 0.0317 0.0267 1 0.056149 1 del_10q23.31 116 (26%) 325 9.9999e-06 0.0089 3e-05 0.0199 0.062829 1 0.00012 0.0722 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00224 1 0.050329 1 del_11p15.5 97 (22%) 344 9.9999e-06 0.0089 7.9999e-05 0.0491 4e-05 0.0257 0.0051199 1 0.00362 1 0.03127 1 8.9999e-05 0.0547 0.00174 0.846 0.20778 1 0.53486 1 del_11q23.2 99 (22%) 342 9.9999e-06 0.0089 0.01675 1 0.70413 1 0.15515 1 0.00095999 0.493 0.00013 0.0779 0.19633 1 0.071979 1 0.0293 1 0.19042 1 del_12p13.1 77 (17%) 364 9.9999e-06 0.0089 9.9999e-06 0.0089 0.54015 1 0.41761 1 5.9999e-05 0.0374 3e-05 0.0199 0.00029 0.165 0.00329 1 0.20375 1 0.04989 1 del_12q12 59 (13%) 382 9.9999e-06 0.0089 7.9999e-05 0.0491 0.92127 1 0.93254 1 0.096529 1 0.13996 1 0.30829 1 0.03989 1 0.79556 1 0.69266 1 del_13q12.11 63 (14%) 378 9.9999e-06 0.0089 0.069719 1 0.42732 1 0.3673 1 0.066289 1 0.02097 1 0.075389 1 0.27729 1 0.98811 1 0.37086 1 del_14q23.3 136 (31%) 305 9.9999e-06 0.0089 9.9999e-06 0.0089 0.74944 1 0.42878 1 5e-05 0.0317 0.00027 0.154 9.9999e-06 0.0089 9.9999e-06 0.0089 0.04556 1 0.00262 1 del_14q32.32 133 (30%) 308 9.9999e-06 0.0089 0.00016 0.0944 0.7674 1 0.58957 1 0.00183 0.888 0.00055999 0.301 0.00014 0.083 0.0071399 1 0.25718 1 0.056489 1 del_15q11.2 120 (27%) 321 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00167 0.818 0.26698 1 9.9999e-06 0.0089 2e-05 0.0137 4e-04 0.221 6.9999e-05 0.0433 0.02949 1 0.00036 0.201 del_15q15.1 122 (28%) 319 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00365 1 0.29373 1 9.9999e-06 0.0089 9.9999e-06 0.0089 5e-05 0.0317 9.9999e-06 0.0089 0.0057699 1 0.00017 0.0998 del_16p13.3 93 (21%) 348 9.9999e-06 0.0089 0.00034 0.19 0.70085 1 0.81836 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.087849 1 del_16q23.1 182 (41%) 259 9.9999e-06 0.0089 0.00233 1 0.46915 1 0.16855 1 0.00195 0.936 0.0085499 1 0.00013 0.0779 0.00363 1 0.0087799 1 0.03223 1 del_17p13.3 176 (40%) 265 9.9999e-06 0.0089 9.9999e-06 0.0089 0.55515 1 0.02029 1 2e-05 0.0137 9.9999e-06 0.0089 9.9999e-06 0.0089 6.9999e-05 0.0433 0.061219 1 0.00246 1 del_17p12 181 (41%) 260 9.9999e-06 0.0089 9.9999e-06 0.0089 0.3958 1 0.0080999 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 0.01601 1 0.00013 0.0779 del_17q24.3 76 (17%) 365 9.9999e-06 0.0089 0.00082999 0.432 0.17755 1 0.26494 1 0.01745 1 0.0054499 1 0.0064499 1 0.04151 1 0.23345 1 0.56064 1 del_18q12.2 181 (41%) 260 9.9999e-06 0.0089 0.00132 0.661 0.91313 1 0.73714 1 0.00476 1 0.057599 1 5.9999e-05 0.0374 4e-04 0.221 0.00090999 0.47 0.0080499 1 del_18q21.2 204 (46%) 237 9.9999e-06 0.0089 0.00073999 0.389 0.66493 1 0.45043 1 0.00032 0.18 0.00429 1 5e-05 0.0317 0.00188 0.906 0.00108 0.552 0.0099699 1 del_19p13.3 162 (37%) 279 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00368 1 0.00456 1 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 9.9999e-06 0.0089 3e-05 0.0199 del_19q13.11 75 (17%) 366 9.9999e-06 0.0089 9.9999e-06 0.0089 0.063829 1 0.71061 1 4e-05 0.0257 0.00070999 0.376 9.9999e-06 0.0089 9.9999e-06 0.0089 0.0054099 1 0.0088999 1 del_20p12.1 39 (9%) 402 0.00118 0.596 0.00151 0.749 0.65845 1 0.19358 1 0.015 1 0.084329 1 0.00124 0.624 0.055169 1 0.6625 1 0.04062 1 del_21q11.2 183 (41%) 258 9.9999e-06 0.0089 0.00034 0.19 0.23364 1 0.14697 1 0.00257 1 0.00257 1 3e-05 0.0199 0.00089999 0.468 0.00163 0.8 0.092559 1 del_21q22.3 193 (44%) 248 9.9999e-06 0.0089 0.0090999 1 0.19905 1 0.29364 1 0.0055899 1 0.00037 0.206 0.00022 0.127 0.00294 1 0.00029 0.165 0.092889 1 del_22q13.31 161 (37%) 280 9.9999e-06 0.0089 9.9999e-06 0.0089 0.04981 1 0.0059699 1 0.0014 0.699 0.0039 1 9.9999e-06 0.0089 9.9999e-06 0.0089 0.00013 0.0779 0.01421 1 del_xp22.2 85 (19%) 356 9.9999e-06 0.0089 2e-05 0.0137 0.46313 1 0.04402 1 0.00021 0.121 0.00022 0.127 0.051129 1 0.00271 1 0.34009 1 0.28887 1 del_xp21.1 74 (17%) 367 9.9999e-06 0.0089 0.00299 1 0.16042 1 0.03242 1 0.0078199 1 0.060079 1 0.13073 1 0.24264 1 0.48621 1 0.61852 1 del_xq21.33 56 (13%) 385 9.9999e-06 0.0089 0.00033 0.185 0.81491 1 0.03467 1 0.0087999 1 0.050479 1 0.01318 1 0.063629 1 0.096149 1 0.059139 1