Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.023 0.1 0.221 48.0 -9999.0 0.0 48.0 KIRREL 0.001 0.053 -9999.0 0.0 -0.298 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.023 0.101 -9999.0 0.0 -0.221 48.0 48.0 PLCG1 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.02 0.122 -9999.0 0.0 -0.221 55.0 55.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.095 -9999.0 0.0 -0.254 15.0 15.0 FYN -0.039 0.107 0.258 6.0 -0.211 54.0 60.0 mol:Ca2+ -0.021 0.115 -9999.0 0.0 -0.22 48.0 48.0 mol:DAG -0.021 0.115 -9999.0 0.0 -0.221 48.0 48.0 NPHS2 -0.059 0.157 -9999.0 0.0 -0.385 50.0 50.0 mol:IP3 -0.021 0.115 -9999.0 0.0 -0.221 48.0 48.0 regulation of endocytosis -0.022 0.106 -9999.0 0.0 -0.199 54.0 54.0 Nephrin/NEPH1/podocin/Cholesterol -0.031 0.115 -9999.0 0.0 -0.208 64.0 64.0 establishment of cell polarity -0.023 0.1 -9999.0 0.0 -0.221 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.009 0.119 -9999.0 0.0 -0.297 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.021 0.108 -9999.0 0.0 -0.202 53.0 53.0 NPHS1 -0.043 0.123 -9999.0 0.0 -0.296 49.0 49.0 Nephrin/NEPH1/podocin -0.027 0.11 -9999.0 0.0 -0.21 56.0 56.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.116 -9999.0 0.0 -0.222 48.0 48.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.021 0.123 -9999.0 0.0 -0.221 55.0 55.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.044 0.103 0.198 9.0 -0.206 53.0 62.0 cytoskeleton organization -0.047 0.103 0.206 2.0 -0.239 50.0 52.0 Nephrin/NEPH1 -0.01 0.07 -9999.0 0.0 -0.149 45.0 45.0 Nephrin/NEPH1/ZO-1 -0.004 0.087 -9999.0 0.0 -0.175 44.0 44.0