		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	37 (25%)	113	0.00302	1	0.00063999	0.304	0.00037	0.181	0.00245	1	0.055219	1	0.15959	1	0.0042	1	0.03321	1
1q gain	61 (41%)	89	0.43813	1	0.66396	1	0.82456	1	0.059349	1	0.12498	1	1	1	0.75282	1	0.31758	1
2p gain	46 (31%)	104	0.01367	1	0.0092699	1	0.01617	1	0.16732	1	0.059189	1	0.087379	1	0.083539	1	0.18026	1
2q gain	42 (28%)	108	0.11606	1	0.03307	1	0.2772	1	0.74584	1	0.50079	1	0.27762	1	0.12809	1	0.75942	1
3p gain	27 (18%)	123	0.02278	1	0.39997	1	0.0072399	1	0.0066199	1	0.062369	1	0.01893	1	0.03778	1	0.13413	1
3q gain	36 (24%)	114	0.0073499	1	0.18055	1	0.03115	1	0.03206	1	0.19174	1	0.16591	1	0.28423	1	0.69796	1
4p gain	3 (2%)	147	0.63593	1	0.19684	1	1	1	0.68088	1	NA	NA	NA	NA	NA	NA	NA	NA
5p gain	6 (4%)	144	0.67239	1	0.02545	1	0.01116	1	0.0081799	1	0.01804	1	0.3513	1	0.01804	1	0.25067	1
5q gain	3 (2%)	147	0.77732	1	0.058769	1	0.03562	1	0.0417	1	NA	NA	NA	NA	NA	NA	NA	NA
6p gain	28 (19%)	122	0.00054999	0.264	0.7519	1	0.01294	1	0.00080999	0.383	0.00434	1	0.00192	0.887	0.0386	1	0.02935	1
6q gain	23 (15%)	127	0.02336	1	0.883	1	0.01387	1	0.00025	0.123	0.066839	1	0.02661	1	0.16374	1	0.077609	1
7p gain	121 (81%)	29	0.00449	1	0.057389	1	0.00419	1	0.0083199	1	0.12808	1	0.11358	1	0.18685	1	0.58321	1
7q gain	105 (70%)	45	0.54733	1	0.068979	1	0.00476	1	0.01214	1	0.10566	1	0.03797	1	0.02796	1	0.1055	1
8p gain	110 (73%)	40	0.063679	1	0.0054799	1	3e-05	0.0154	0.00023	0.114	0.061989	1	0.02657	1	0.01532	1	0.065839	1
8q gain	111 (74%)	39	0.02035	1	0.00322	1	0.00013	0.0651	0.00025	0.123	0.00464	1	0.00328	1	0.0081299	1	0.0066499	1
9p gain	16 (11%)	134	0.2346	1	0.33526	1	0.15799	1	0.29703	1	0.61355	1	0.099449	1	0.32061	1	0.73728	1
9q gain	17 (11%)	133	0.15233	1	0.49999	1	1	1	0.079229	1	1	1	1	1	0.66009	1	0.30092	1
10p gain	6 (4%)	144	0.58281	1	0.092869	1	0.32195	1	0.34517	1	NA	NA	NA	NA	NA	NA	NA	NA
10q gain	8 (5%)	142	0.59455	1	0.38713	1	0.36873	1	0.22519	1	NA	NA	NA	NA	NA	NA	NA	NA
11p gain	10 (7%)	140	0.27335	1	0.18277	1	0.1655	1	0.051359	1	0.61361	1	0.56131	1	0.22891	1	0.34643	1
11q gain	4 (3%)	146	0.38657	1	0.14996	1	0.077599	1	0.01302	1	NA	NA	NA	NA	NA	NA	NA	NA
12p gain	146 (97%)	4	0.19317	1	0.38802	1	0.80888	1	0.36842	1	0.069519	1	1	1	0.3598	1	0.89982	1
12q gain	100 (67%)	50	0.56564	1	0.84096	1	0.20502	1	0.33873	1	0.34812	1	0.8461	1	0.98633	1	0.75444	1
14q gain	51 (34%)	99	0.25279	1	0.23596	1	0.5854	1	0.3964	1	0.48001	1	0.71263	1	0.71	1	0.94853	1
15q gain	51 (34%)	99	0.04991	1	0.00215	0.987	9.9999e-06	0.00548	3e-05	0.0154	0.01886	1	0.01103	1	0.02621	1	0.02026	1
16p gain	16 (11%)	134	0.01197	1	0.079699	1	0.00425	1	0.01719	1	0.11046	1	0.01393	1	0.0287	1	0.03664	1
16q gain	14 (9%)	136	0.0075599	1	0.13874	1	0.0101	1	0.04889	1	0.10877	1	0.01403	1	0.02945	1	0.03746	1
17p gain	40 (27%)	110	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	0.00147	0.684	0.00052999	0.255	0.00062999	0.3	0.00209	0.961
17q gain	51 (34%)	99	0.00016	0.0798	6.9999e-05	0.0353	9.9999e-06	0.00548	9.9999e-06	0.00548	0.00034	0.167	0.00041	0.2	7.9999e-05	0.0402	0.00299	1
18p gain	4 (3%)	146	0.68841	1	0.070279	1	0.37704	1	0.78342	1	NA	NA	NA	NA	NA	NA	NA	NA
19p gain	36 (24%)	114	0.0098299	1	4e-05	0.0204	6.9999e-05	0.0353	0.00083999	0.396	0.02525	1	0.088319	1	0.36858	1	0.25236	1
19q gain	29 (19%)	121	0.01617	1	0.00018	0.0896	2e-05	0.0103	0.00058999	0.282	0.19571	1	0.04847	1	0.36969	1	0.22027	1
20p gain	34 (23%)	116	0.0054399	1	0.11294	1	0.04119	1	0.28604	1	0.10053	1	0.083769	1	0.1105	1	0.27209	1
20q gain	40 (27%)	110	0.0066799	1	0.0058399	1	0.0068499	1	0.053169	1	0.062409	1	0.12388	1	0.1081	1	0.15024	1
21q gain	125 (83%)	25	0.40244	1	0.27278	1	0.084039	1	0.23823	1	0.090889	1	0.21456	1	0.45243	1	0.25373	1
22q gain	38 (25%)	112	9.9999e-06	0.00548	0.00138	0.644	2e-05	0.0103	9.9999e-06	0.00548	0.051959	1	0.00276	1	0.02079	1	0.00137	0.641
xq gain	22 (15%)	128	0.00187	0.866	0.01773	1	0.00081999	0.387	0.00363	1	0.02088	1	0.04938	1	0.15467	1	0.37745	1
1p loss	18 (12%)	132	0.12085	1	0.56972	1	0.64897	1	0.88719	1	0.34528	1	0.35165	1	0.1138	1	0.50773	1
1q loss	8 (5%)	142	0.34424	1	0.24258	1	0.29106	1	0.21699	1	0.0422	1	0.01423	1	0.00381	1	0.077209	1
2p loss	5 (3%)	145	0.86206	1	0.37737	1	1	1	1	1	0.23146	1	1	1	0.20694	1	0.67887	1
2q loss	6 (4%)	144	0.44401	1	0.68078	1	0.55641	1	0.90066	1	0.23053	1	0.20458	1	0.7022	1	0.60094	1
3p loss	30 (20%)	120	0.93539	1	0.03028	1	0.00151	0.701	0.00342	1	0.01949	1	0.03639	1	0.11638	1	0.18656	1
3q loss	22 (15%)	128	0.74075	1	0.73875	1	0.085379	1	0.057239	1	0.054789	1	0.18414	1	0.086729	1	0.53867	1
4p loss	92 (61%)	58	0.62969	1	0.0455	1	0.0312	1	0.16321	1	0.14043	1	0.13863	1	0.48135	1	0.31896	1
4q loss	108 (72%)	42	0.066899	1	0.01078	1	0.01079	1	0.01217	1	0.12039	1	0.10705	1	0.62634	1	0.50816	1
5p loss	103 (69%)	47	0.11332	1	0.20845	1	0.11458	1	0.1316	1	0.52952	1	0.12511	1	0.23687	1	0.30787	1
5q loss	101 (67%)	49	0.058979	1	0.062709	1	0.014	1	0.00338	1	0.5005	1	0.04862	1	0.10279	1	0.15423	1
6p loss	13 (9%)	137	0.26546	1	0.037	1	0.16057	1	0.01419	1	0.92453	1	0.56298	1	0.54613	1	0.70503	1
6q loss	16 (11%)	134	0.12111	1	0.0093999	1	0.04489	1	0.00103	0.484	0.94971	1	0.62612	1	0.76301	1	0.78784	1
8p loss	12 (8%)	138	0.35647	1	0.050689	1	0.01049	1	0.04739	1	0.42186	1	0.28066	1	0.055289	1	0.32711	1
8q loss	5 (3%)	145	0.18765	1	0.02393	1	0.0022	1	0.01254	1	NA	NA	NA	NA	NA	NA	NA	NA
9p loss	63 (42%)	87	0.03283	1	1	1	0.86846	1	0.43659	1	0.43611	1	0.54785	1	0.28506	1	0.5939	1
9q loss	58 (39%)	92	0.00032	0.157	0.33841	1	0.30824	1	0.01729	1	0.67577	1	0.03384	1	0.12665	1	0.30904	1
10p loss	77 (51%)	73	0.02157	1	0.00042	0.204	0.00034	0.167	0.0055099	1	0.96337	1	0.44734	1	0.4455	1	0.44258	1
10q loss	72 (48%)	78	0.0085799	1	5.9999e-05	0.0304	0.00023	0.114	0.00258	1	0.3633	1	0.076539	1	0.11444	1	0.076459	1
11p loss	98 (65%)	52	0.0086499	1	0.18263	1	0.00048	0.232	0.00051999	0.251	0.00047	0.227	0.00046	0.223	0.0050099	1	0.017	1
11q loss	115 (77%)	35	9.9999e-06	0.00548	0.12347	1	9.9999e-05	0.0502	2e-05	0.0103	0.00019	0.0944	0.0067299	1	0.0080299	1	0.01684	1
13q loss	113 (75%)	37	0.04412	1	0.28883	1	0.03232	1	0.0014	0.652	0.13235	1	0.13358	1	0.0060799	1	0.04127	1
14q loss	20 (13%)	130	0.12077	1	0.00059999	0.286	0.00482	1	5e-05	0.0254	0.053789	1	0.00484	1	0.01117	1	0.058969	1
15q loss	29 (19%)	121	0.0062999	1	3e-05	0.0154	9.9999e-06	0.00548	9.9999e-06	0.00548	0.01068	1	0.00273	1	0.00066999	0.318	0.0011	0.516
16p loss	44 (29%)	106	0.14885	1	0.0067999	1	0.080759	1	0.26164	1	0.10667	1	0.28717	1	0.39578	1	0.17852	1
16q loss	51 (34%)	99	0.078519	1	0.066209	1	0.23237	1	0.48384	1	0.077159	1	0.28621	1	0.39733	1	0.35185	1
17p loss	37 (25%)	113	9.9999e-06	0.00548	0.03839	1	0.00428	1	0.00014	0.07	0.02162	1	0.078559	1	0.00298	1	0.02154	1
17q loss	16 (11%)	134	0.0056699	1	0.12914	1	0.01972	1	0.02798	1	0.077339	1	0.04828	1	0.01569	1	0.075159	1
18p loss	116 (77%)	34	0.69204	1	0.075259	1	0.04427	1	0.24282	1	0.12432	1	0.098909	1	0.084409	1	0.10802	1
18q loss	122 (81%)	28	0.085519	1	0.3175	1	0.066319	1	0.12361	1	0.055629	1	0.067679	1	0.01138	1	0.01054	1
19p loss	50 (33%)	100	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548
19q loss	53 (35%)	97	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548
20p loss	30 (20%)	120	0.2349	1	0.18841	1	0.19852	1	0.17082	1	0.70238	1	0.13632	1	0.26808	1	0.15947	1
20q loss	15 (10%)	135	0.58643	1	0.4899	1	0.19911	1	0.26956	1	0.2947	1	0.12012	1	0.10053	1	0.39253	1
22q loss	45 (30%)	105	0.00268	1	9.9999e-06	0.00548	9.9999e-06	0.00548	9.9999e-06	0.00548	0.00249	1	2e-05	0.0103	5e-05	0.0254	0.00054999	0.264
xq loss	29 (19%)	121	0.00033	0.162	0.00194	0.894	0.16236	1	0.096589	1	0.35555	1	0.24295	1	0.084809	1	0.15737	1
