Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.122 0.278 0.728 25.0 -9999.0 0.0 25.0 KIRREL -0.094 0.284 -9999.0 0.0 -0.886 17.0 17.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.122 0.279 -9999.0 0.0 -0.73 25.0 25.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.098 0.224 -9999.0 0.0 -0.573 25.0 25.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.044 0.176 -9999.0 0.0 -0.42 25.0 25.0 FYN -0.073 0.22 -9999.0 0.0 -0.542 25.0 25.0 mol:Ca2+ -0.096 0.22 -9999.0 0.0 -0.566 25.0 25.0 mol:DAG -0.097 0.222 -9999.0 0.0 -0.57 25.0 25.0 NPHS2 -0.013 0.064 -9999.0 0.0 -0.414 3.0 3.0 mol:IP3 -0.097 0.222 -9999.0 0.0 -0.57 25.0 25.0 regulation of endocytosis -0.086 0.198 -9999.0 0.0 -0.507 25.0 25.0 Nephrin/NEPH1/podocin/Cholesterol -0.099 0.227 -9999.0 0.0 -0.581 25.0 25.0 establishment of cell polarity -0.122 0.278 -9999.0 0.0 -0.728 25.0 25.0 Nephrin/NEPH1/podocin/NCK1-2 -0.09 0.207 -9999.0 0.0 -0.527 25.0 25.0 Nephrin/NEPH1/beta Arrestin2 -0.087 0.202 -9999.0 0.0 -0.515 25.0 25.0 NPHS1 -0.056 0.225 -9999.0 0.0 -0.893 10.0 10.0 Nephrin/NEPH1/podocin -0.093 0.213 -9999.0 0.0 -0.546 25.0 25.0 TJP1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.098 0.224 -9999.0 0.0 -0.573 25.0 25.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.098 0.224 -9999.0 0.0 -0.573 25.0 25.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.086 0.232 -9999.0 0.0 -0.545 28.0 28.0 cytoskeleton organization -0.06 0.232 -9999.0 0.0 -0.554 25.0 25.0 Nephrin/NEPH1 -0.094 0.217 -9999.0 0.0 -0.561 25.0 25.0 Nephrin/NEPH1/ZO-1 -0.101 0.235 -9999.0 0.0 -0.609 25.0 25.0