Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.061 0.222 0.546 25.0 -9999.0 0.0 25.0 KIRREL -0.06 0.224 -9999.0 0.0 -0.684 17.0 17.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.061 0.222 -9999.0 0.0 -0.548 25.0 25.0 PLCG1 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.023 0.185 -9999.0 0.0 -0.424 25.0 25.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.037 0.141 -9999.0 0.0 -0.342 25.0 25.0 FYN -0.051 0.163 0.27 1.0 -0.399 25.0 26.0 mol:Ca2+ -0.024 0.182 -9999.0 0.0 -0.42 25.0 25.0 mol:DAG -0.023 0.184 -9999.0 0.0 -0.422 25.0 25.0 NPHS2 0.006 0.041 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.023 0.184 -9999.0 0.0 -0.422 25.0 25.0 regulation of endocytosis -0.023 0.164 -9999.0 0.0 -0.378 25.0 25.0 Nephrin/NEPH1/podocin/Cholesterol -0.035 0.179 -9999.0 0.0 -0.423 25.0 25.0 establishment of cell polarity -0.061 0.222 -9999.0 0.0 -0.546 25.0 25.0 Nephrin/NEPH1/podocin/NCK1-2 -0.008 0.178 -9999.0 0.0 -0.392 25.0 25.0 Nephrin/NEPH1/beta Arrestin2 -0.022 0.167 -9999.0 0.0 -0.383 25.0 25.0 NPHS1 -0.031 0.178 -9999.0 0.0 -0.689 10.0 10.0 Nephrin/NEPH1/podocin -0.029 0.172 -9999.0 0.0 -0.401 25.0 25.0 TJP1 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.023 0.185 -9999.0 0.0 -0.424 25.0 25.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.023 0.185 -9999.0 0.0 -0.424 25.0 25.0 GRB2 0.025 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.054 0.165 0.281 2.0 -0.391 26.0 28.0 cytoskeleton organization -0.062 0.174 -9999.0 0.0 -0.435 25.0 25.0 Nephrin/NEPH1 -0.042 0.167 -9999.0 0.0 -0.403 25.0 25.0 Nephrin/NEPH1/ZO-1 -0.036 0.191 -9999.0 0.0 -0.452 25.0 25.0