Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 5 (1%) 496 0.00105 0.407 0.83898 1 NA NA NA NA 0.92154 1 0.88148 1 0.10795 1 0.051639 1 0.27606 1 0.1424 1 1q gain 26 (5%) 475 9.9999e-06 0.00534 0.0166 1 0.00281 1 0.064499 1 0.00112 0.431 6.9999e-05 0.0316 0.085899 1 0.050579 1 0.01331 1 0.0156 1 3p gain 3 (1%) 498 0.00159 0.601 0.54834 1 NA NA NA NA 0.49602 1 0.59165 1 0.30467 1 0.18656 1 1 1 0.19262 1 4p gain 5 (1%) 496 9.9999e-06 0.00534 0.0064499 1 NA NA NA NA 0.01642 1 0.01257 1 0.04161 1 0.01471 1 1 1 0.076689 1 4q gain 5 (1%) 496 5e-05 0.023 0.0067599 1 NA NA NA NA 0.01707 1 0.01231 1 0.04042 1 0.01416 1 1 1 0.077219 1 5p gain 21 (4%) 480 9.9999e-06 0.00534 0.00198 0.739 0.52886 1 0.23259 1 0.0051699 1 0.00011 0.0486 0.00099999 0.389 9.9999e-05 0.0445 0.5981 1 0.00366 1 5q gain 17 (3%) 484 9.9999e-06 0.00534 5e-05 0.023 0.84877 1 0.079489 1 0.00013 0.0573 3e-05 0.0141 2e-04 0.0848 9.9999e-06 0.00534 0.83969 1 0.00425 1 7p gain 18 (4%) 483 9.9999e-06 0.00534 5e-05 0.023 0.6592 1 0.052359 1 0.00064999 0.259 0.00013 0.0573 0.00034 0.14 4e-05 0.0187 0.57772 1 0.0053799 1 7q gain 20 (4%) 481 9.9999e-06 0.00534 9.9999e-06 0.00534 0.57211 1 0.01414 1 9.9999e-05 0.0445 4e-05 0.0187 6.9999e-05 0.0316 9.9999e-06 0.00534 0.61191 1 0.00061999 0.249 8p gain 6 (1%) 495 0.00015 0.0657 0.41607 1 0.45482 1 0.62895 1 0.59721 1 0.53554 1 0.45357 1 0.45166 1 1 1 1 1 8q gain 7 (1%) 494 2e-05 0.00962 0.20183 1 0.45471 1 0.6326 1 0.82967 1 0.52012 1 0.79977 1 0.62973 1 0.89957 1 0.89683 1 9p gain 3 (1%) 498 0.00143 0.545 0.55044 1 NA NA NA NA 0.49547 1 0.58755 1 1 1 1 1 0.4208 1 0.63164 1 9q gain 4 (1%) 497 0.01097 1 0.79268 1 NA NA NA NA 0.90023 1 0.3611 1 0.83931 1 1 1 0.16654 1 0.56783 1 11p gain 6 (1%) 495 0.00112 0.431 0.02843 1 0.77914 1 0.30117 1 0.053799 1 0.04417 1 0.0089299 1 0.0068499 1 0.46759 1 0.097729 1 11q gain 5 (1%) 496 0.00016 0.0696 0.060379 1 0.77876 1 0.30002 1 0.1099 1 0.12364 1 0.02638 1 0.02251 1 0.31051 1 0.27292 1 12p gain 14 (3%) 487 9.9999e-06 0.00534 9.9999e-06 0.00534 0.84957 1 0.081129 1 2e-05 0.00962 9.9999e-06 0.00534 5.9999e-05 0.0271 9.9999e-06 0.00534 0.5516 1 0.00242 0.888 12q gain 15 (3%) 486 9.9999e-06 0.00534 9.9999e-06 0.00534 0.85061 1 0.078899 1 9.9999e-06 0.00534 9.9999e-06 0.00534 3e-05 0.0141 9.9999e-06 0.00534 0.38323 1 0.00085999 0.337 13q gain 5 (1%) 496 4e-05 0.0187 0.01894 1 0.38014 1 0.2127 1 0.04916 1 0.10172 1 0.23942 1 0.070309 1 0.84421 1 0.1975 1 14q gain 11 (2%) 490 9.9999e-06 0.00534 0.00022 0.0931 1 1 0.15783 1 0.00049 0.2 8.9999e-05 0.0401 0.00059999 0.242 5e-05 0.023 0.85158 1 0.00201 0.748 16p gain 15 (3%) 486 9.9999e-06 0.00534 4e-05 0.0187 0.63322 1 0.079599 1 0.00018 0.077 5e-05 0.023 0.00015 0.0657 9.9999e-06 0.00534 0.43493 1 0.00075999 0.3 16q gain 13 (3%) 488 9.9999e-06 0.00534 0.00016 0.0696 0.79674 1 0.27603 1 0.00093999 0.367 0.00031 0.129 0.00181 0.679 0.00017 0.0731 0.61659 1 0.0078899 1 17p gain 16 (3%) 485 9.9999e-06 0.00534 9.9999e-06 0.00534 0.53766 1 0.02785 1 9.9999e-06 0.00534 9.9999e-06 0.00534 2e-05 0.00962 9.9999e-06 0.00534 0.35774 1 0.00024 0.1 17q gain 18 (4%) 483 9.9999e-06 0.00534 9.9999e-06 0.00534 0.63498 1 0.01529 1 9.9999e-06 0.00534 9.9999e-06 0.00534 2e-05 0.00962 9.9999e-06 0.00534 0.5134 1 0.00027 0.112 18p gain 6 (1%) 495 5e-05 0.023 0.091879 1 NA NA NA NA 0.122 1 0.26694 1 0.25597 1 0.11143 1 0.45401 1 0.39873 1 18q gain 6 (1%) 495 3e-05 0.0141 0.091999 1 NA NA NA NA 0.12013 1 0.26515 1 0.25392 1 0.11353 1 0.45414 1 0.39346 1 19p gain 8 (2%) 493 9.9999e-06 0.00534 0.00019 0.0809 NA NA NA NA 0.00062999 0.252 0.00022 0.0931 6.9999e-05 0.0316 2e-05 0.00962 0.44907 1 0.02258 1 19q gain 10 (2%) 491 9.9999e-06 0.00534 2e-05 0.00962 0.63456 1 0.064179 1 9.9999e-05 0.0445 4e-05 0.0187 2e-05 0.00962 9.9999e-06 0.00534 0.63676 1 0.0016 0.603 20p gain 12 (2%) 489 9.9999e-06 0.00534 0.00032 0.132 0.79614 1 0.092929 1 0.00257 0.935 0.00089999 0.352 0.00453 1 0.00049 0.2 0.91306 1 0.095019 1 20q gain 12 (2%) 489 9.9999e-06 0.00534 0.00044 0.18 0.79459 1 0.092689 1 0.00251 0.916 0.00066999 0.267 0.00426 1 0.00076999 0.303 0.91467 1 0.093099 1 21q gain 5 (1%) 496 0.00015 0.0657 0.16899 1 NA NA NA NA 0.23773 1 0.48839 1 0.45294 1 0.31211 1 0.69231 1 0.68098 1 xq gain 9 (2%) 492 9.9999e-06 0.00534 0.01097 1 0.83764 1 0.50135 1 0.097389 1 0.14126 1 0.2771 1 0.13257 1 0.90825 1 0.39821 1 1p loss 4 (1%) 497 0.00019 0.0809 0.18639 1 NA NA NA NA 0.24328 1 0.31608 1 0.11474 1 0.066299 1 0.84522 1 0.19465 1 1q loss 3 (1%) 498 0.00137 0.523 0.050459 1 NA NA NA NA 0.097179 1 0.15366 1 0.02799 1 0.01757 1 1 1 0.19015 1 2p loss 10 (2%) 491 9.9999e-06 0.00534 3e-05 0.0141 0.77491 1 0.092019 1 7.9999e-05 0.0358 2e-05 0.00962 9.9999e-06 0.00534 2e-05 0.00962 0.23499 1 0.00036 0.148 2q loss 10 (2%) 491 9.9999e-06 0.00534 2e-05 0.00962 0.77305 1 0.089299 1 0.00013 0.0573 5e-05 0.023 9.9999e-06 0.00534 9.9999e-06 0.00534 0.23401 1 0.00055999 0.226 3p loss 3 (1%) 498 0.00123 0.471 0.04889 1 NA NA NA NA 0.099519 1 0.15186 1 0.02657 1 0.01622 1 1 1 0.19181 1 3q loss 4 (1%) 497 0.00016 0.0696 0.01808 1 0.49531 1 0.41998 1 0.03723 1 0.04783 1 0.0087799 1 0.00408 1 1 1 0.066929 1 6p loss 4 (1%) 497 0.00016 0.0696 0.04567 1 NA NA NA NA 0.45969 1 0.39852 1 0.11467 1 0.067459 1 0.40073 1 0.19465 1 6q loss 7 (1%) 494 4e-05 0.0187 0.00219 0.808 0.01306 1 0.57353 1 0.02725 1 0.01808 1 0.00489 1 0.00059999 0.242 1 1 0.0099499 1 8p loss 4 (1%) 497 0.00018 0.077 0.01809 1 NA NA NA NA 0.03577 1 0.04712 1 0.0078399 1 0.00398 1 0.11039 1 0.01863 1 8q loss 4 (1%) 497 0.00016 0.0696 0.0182 1 NA NA NA NA 0.03553 1 0.04637 1 0.0084099 1 0.0039 1 0.10981 1 0.0192 1 9p loss 19 (4%) 482 9.9999e-06 0.00534 0.0377 1 0.24269 1 0.64752 1 0.03116 1 0.062359 1 0.0087899 1 0.0070599 1 0.30302 1 0.00387 1 9q loss 25 (5%) 476 9.9999e-06 0.00534 0.10386 1 0.17215 1 0.11611 1 0.17135 1 0.062789 1 0.0097899 1 0.0063699 1 0.27927 1 0.00499 1 10p loss 7 (1%) 494 9.9999e-06 0.00534 0.01112 1 0.49327 1 0.41959 1 0.01954 1 0.01535 1 0.00466 1 0.00068999 0.274 1 1 0.01029 1 10q loss 6 (1%) 495 9.9999e-06 0.00534 0.02906 1 NA NA NA NA 0.051569 1 0.04404 1 0.01438 1 0.00439 1 1 1 0.0287 1 11p loss 7 (1%) 494 9.9999e-06 0.00534 0.01127 1 0.49405 1 0.95835 1 0.0072199 1 0.01864 1 0.00477 1 0.00073999 0.293 0.79761 1 0.01088 1 11q loss 9 (2%) 492 9.9999e-06 0.00534 0.0158 1 0.31936 1 0.8122 1 0.01523 1 0.0184 1 0.00050999 0.207 0.00248 0.908 0.90833 1 0.00201 0.748 13q loss 14 (3%) 487 0.00164 0.617 0.01497 1 0.061079 1 0.13867 1 0.0054699 1 0.0086399 1 0.00108 0.418 0.00054999 0.223 0.10444 1 0.01303 1 15q loss 8 (2%) 493 0.00023 0.0966 0.00022 0.0931 0.19269 1 0.087859 1 0.00048 0.196 0.00026 0.108 6.9999e-05 0.0316 5e-05 0.023 0.40667 1 0.00154 0.585 17p loss 8 (2%) 493 0.01449 1 0.41468 1 1 1 0.39099 1 0.63807 1 0.59896 1 0.091939 1 0.1622 1 0.12865 1 0.20464 1 17q loss 4 (1%) 497 0.11282 1 0.7903 1 NA NA NA NA 0.90147 1 0.66567 1 0.4659 1 0.56763 1 0.33089 1 0.68445 1 18p loss 4 (1%) 497 0.00191 0.714 0.1831 1 1 1 0.38787 1 0.24505 1 0.31559 1 0.075829 1 0.092319 1 0.53127 1 0.27337 1 18q loss 4 (1%) 497 0.0021 0.777 0.18513 1 1 1 0.38742 1 0.24562 1 0.318 1 0.072339 1 0.090649 1 0.5341 1 0.27727 1 19p loss 5 (1%) 496 0.0091499 1 0.0074299 1 0.32133 1 0.23717 1 0.01701 1 0.01252 1 0.00239 0.88 0.00108 0.418 0.087619 1 0.00155 0.587 21q loss 8 (2%) 493 0.00079999 0.314 0.16253 1 0.38381 1 0.21545 1 0.71145 1 0.4201 1 0.093229 1 0.0291 1 0.45987 1 0.054489 1 22q loss 89 (18%) 412 9.9999e-06 0.00534 9.9999e-06 0.00534 0.11648 1 0.50257 1 9.9999e-06 0.00534 9.9999e-06 0.00534 0.00035 0.144 5e-05 0.023 0.00017 0.0731 0.00023 0.0966 xq loss 3 (1%) 498 0.050739 1 0.04898 1 0.28038 1 0.1989 1 0.098879 1 0.15099 1 0.02759 1 0.01651 1 0.11054 1 0.01898 1