Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.166 0.304 0.687 121.0 -9999.0 0.0 121.0 KIRREL -0.072 0.24 -9999.0 0.0 -0.841 44.0 44.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.167 0.305 -9999.0 0.0 -0.689 121.0 121.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.13 0.241 -9999.0 0.0 -0.537 121.0 121.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.076 0.196 -9999.0 0.0 -0.408 121.0 121.0 FYN -0.11 0.236 -9999.0 0.0 -0.508 121.0 121.0 mol:Ca2+ -0.129 0.238 -9999.0 0.0 -0.531 121.0 121.0 mol:DAG -0.129 0.24 -9999.0 0.0 -0.534 121.0 121.0 NPHS2 -0.017 0.052 -9999.0 0.0 -0.89 1.0 1.0 mol:IP3 -0.129 0.24 -9999.0 0.0 -0.534 121.0 121.0 regulation of endocytosis -0.115 0.214 -9999.0 0.0 -0.475 121.0 121.0 Nephrin/NEPH1/podocin/Cholesterol -0.132 0.245 -9999.0 0.0 -0.546 121.0 121.0 establishment of cell polarity -0.166 0.304 -9999.0 0.0 -0.687 121.0 121.0 Nephrin/NEPH1/podocin/NCK1-2 -0.119 0.222 -9999.0 0.0 -0.492 121.0 121.0 Nephrin/NEPH1/beta Arrestin2 -0.102 0.226 -9999.0 0.0 -0.482 121.0 121.0 NPHS1 -0.152 0.318 -9999.0 0.0 -0.819 92.0 92.0 Nephrin/NEPH1/podocin -0.124 0.23 -9999.0 0.0 -0.512 121.0 121.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.13 0.241 -9999.0 0.0 -0.537 121.0 121.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.13 0.241 -9999.0 0.0 -0.537 121.0 121.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.112 0.245 -9999.0 0.0 -0.512 125.0 125.0 cytoskeleton organization -0.101 0.256 -9999.0 0.0 -0.534 121.0 121.0 Nephrin/NEPH1 -0.127 0.236 -9999.0 0.0 -0.526 121.0 121.0 Nephrin/NEPH1/ZO-1 -0.138 0.255 -9999.0 0.0 -0.571 121.0 121.0