Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.104 0.219 -9999.0 0.0 -0.514 65.0 65.0 MAP3K8 0.015 0.079 -9999.0 0.0 -0.632 7.0 7.0 FOS -0.075 0.173 0.304 2.0 -0.443 59.0 61.0 PRKCA -0.008 0.127 -9999.0 0.0 -0.677 17.0 17.0 PTPN7 -0.023 0.134 -9999.0 0.0 -0.673 18.0 18.0 HRAS 0.025 0.011 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.003 0.081 -9999.0 0.0 -0.679 5.0 5.0 NRAS 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.035 0.031 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.012 0.117 -9999.0 0.0 -0.466 22.0 22.0 MAP2K1 -0.015 0.127 -9999.0 0.0 -0.545 21.0 21.0 ELK1 0.013 0.025 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.011 0.114 -9999.0 0.0 -0.52 21.0 21.0 mol:GTP -0.002 0.004 -9999.0 0.0 -0.007 128.0 128.0 MAPK1 -0.099 0.199 -9999.0 0.0 -0.409 121.0 121.0 RAF1 -0.01 0.114 -9999.0 0.0 -0.52 21.0 21.0 KRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0