Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.21 0.301 0.595 43.0 -9999.0 0.0 43.0 KIRREL -0.242 0.36 -9999.0 0.0 -0.756 38.0 38.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.211 0.302 -9999.0 0.0 -0.596 43.0 43.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.152 0.237 -9999.0 0.0 -0.453 43.0 43.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.112 0.19 -9999.0 0.0 -0.352 43.0 43.0 FYN -0.148 0.222 -9999.0 0.0 -0.429 43.0 43.0 mol:Ca2+ -0.151 0.235 -9999.0 0.0 -0.449 43.0 43.0 mol:DAG -0.152 0.236 -9999.0 0.0 -0.451 43.0 43.0 NPHS2 -0.025 0.035 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.152 0.236 -9999.0 0.0 -0.451 43.0 43.0 regulation of endocytosis -0.131 0.212 -9999.0 0.0 -0.4 43.0 43.0 Nephrin/NEPH1/podocin/Cholesterol -0.161 0.236 -9999.0 0.0 -0.46 43.0 43.0 establishment of cell polarity -0.21 0.301 -9999.0 0.0 -0.595 43.0 43.0 Nephrin/NEPH1/podocin/NCK1-2 -0.132 0.221 -9999.0 0.0 -0.412 43.0 43.0 Nephrin/NEPH1/beta Arrestin2 -0.132 0.216 -9999.0 0.0 -0.405 43.0 43.0 NPHS1 -0.057 0.185 -9999.0 0.0 -0.774 7.0 7.0 Nephrin/NEPH1/podocin -0.148 0.224 -9999.0 0.0 -0.432 43.0 43.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.152 0.237 -9999.0 0.0 -0.453 43.0 43.0 CD2AP 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.152 0.237 -9999.0 0.0 -0.453 43.0 43.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.152 0.221 -9999.0 0.0 -0.42 45.0 45.0 cytoskeleton organization -0.139 0.236 -9999.0 0.0 -0.436 43.0 43.0 Nephrin/NEPH1 -0.156 0.228 -9999.0 0.0 -0.444 43.0 43.0 Nephrin/NEPH1/ZO-1 -0.164 0.253 -9999.0 0.0 -0.486 43.0 43.0