Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.028 0.103 0.278 76.0 -9999.0 0.0 76.0 KIRREL -0.039 0.136 -9999.0 0.0 -0.413 63.0 63.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.028 0.103 -9999.0 0.0 -0.279 76.0 76.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.01 0.075 -9999.0 0.0 -0.203 64.0 64.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.077 -9999.0 0.0 -0.209 63.0 63.0 FYN -0.013 0.071 -9999.0 0.0 -0.198 64.0 64.0 mol:Ca2+ -0.014 0.074 -9999.0 0.0 -0.202 64.0 64.0 mol:DAG -0.011 0.075 -9999.0 0.0 -0.202 64.0 64.0 NPHS2 -0.004 0.028 -9999.0 0.0 -0.332 3.0 3.0 mol:IP3 -0.011 0.075 -9999.0 0.0 -0.202 64.0 64.0 regulation of endocytosis -0.005 0.067 -9999.0 0.0 -0.18 64.0 64.0 Nephrin/NEPH1/podocin/Cholesterol -0.017 0.075 -9999.0 0.0 -0.197 78.0 78.0 establishment of cell polarity -0.028 0.103 -9999.0 0.0 -0.278 76.0 76.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.072 -9999.0 0.0 -0.197 32.0 32.0 Nephrin/NEPH1/beta Arrestin2 -0.005 0.068 -9999.0 0.0 -0.182 64.0 64.0 NPHS1 -0.005 0.055 -9999.0 0.0 -0.329 14.0 14.0 Nephrin/NEPH1/podocin -0.013 0.072 -9999.0 0.0 -0.199 64.0 64.0 TJP1 0.01 0.018 -9999.0 0.0 -0.409 1.0 1.0 NCK1 0.009 0.026 -9999.0 0.0 -0.409 2.0 2.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.01 0.075 -9999.0 0.0 -0.203 64.0 64.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.01 0.075 -9999.0 0.0 -0.203 64.0 64.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.026 0.096 -9999.0 0.0 -0.22 93.0 93.0 cytoskeleton organization -0.001 0.08 -9999.0 0.0 -0.214 63.0 63.0 Nephrin/NEPH1 -0.017 0.07 -9999.0 0.0 -0.188 76.0 76.0 Nephrin/NEPH1/ZO-1 -0.013 0.082 -9999.0 0.0 -0.223 64.0 64.0