Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.091 0.205 -9999.0 0.0 -0.524 51.0 51.0 MAP3K8 0.01 0.033 -9999.0 0.0 -0.351 3.0 3.0 FOS -0.062 0.164 -9999.0 0.0 -0.465 47.0 47.0 PRKCA -0.012 0.087 -9999.0 0.0 -0.352 31.0 31.0 PTPN7 0.009 0.036 0.263 6.0 -9999.0 0.0 6.0 HRAS 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.012 0.087 -9999.0 0.0 -0.351 31.0 31.0 NRAS 0.022 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.034 0.217 1.0 -9999.0 0.0 1.0 MAPK3 -0.029 0.135 -9999.0 0.0 -0.682 16.0 16.0 MAP2K1 -0.06 0.152 -9999.0 0.0 -0.405 70.0 70.0 ELK1 0.006 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.041 0.126 -9999.0 0.0 -0.362 62.0 62.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 163.0 163.0 MAPK1 -0.035 0.142 -9999.0 0.0 -0.582 24.0 24.0 RAF1 -0.041 0.132 -9999.0 0.0 -0.382 60.0 60.0 KRAS 0.022 0.014 0.327 1.0 -9999.0 0.0 1.0