Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	24 (43%)	32	0.20235	1	0.75203	1	0.81944	1	0.90252	1	0.52492	1	0.27913	1	0.60775	1	0.56409	1
1q gain	31 (55%)	25	0.44236	1	0.76727	1	0.76285	1	0.62136	1	0.70728	1	0.45543	1	0.88362	1	0.81728	1
2p gain	23 (41%)	33	0.8891	1	0.0074599	1	0.0191	1	0.056609	1	0.49692	1	0.070989	1	0.10243	1	0.13398	1
2q gain	21 (38%)	35	0.37111	1	0.01885	1	0.01235	1	0.11344	1	0.62294	1	0.04894	1	0.19736	1	0.11317	1
3p gain	12 (21%)	44	0.21329	1	0.26044	1	0.43601	1	0.19997	1	0.8585	1	0.26656	1	0.45528	1	0.55199	1
3q gain	23 (41%)	33	0.099699	1	0.04938	1	0.19522	1	0.12113	1	0.49306	1	0.19156	1	0.074279	1	0.22047	1
4p gain	9 (16%)	47	0.73266	1	0.69997	1	0.82182	1	0.86625	1	0.77733	1	0.32736	1	0.26384	1	0.37077	1
4q gain	3 (5%)	53	1	1	0.25793	1	0.51084	1	0.79385	1	0.6739	1	0.56839	1	0.5977	1	0.69693	1
5p gain	23 (41%)	33	0.04385	1	0.37631	1	0.45316	1	0.2454	1	0.74085	1	0.0285	1	0.5951	1	0.15146	1
5q gain	8 (14%)	48	0.50711	1	0.5664	1	0.30728	1	0.24786	1	0.079399	1	0.1537	1	0.12925	1	0.19065	1
6p gain	30 (54%)	26	0.19454	1	0.52197	1	0.60054	1	0.41274	1	1	1	0.47216	1	0.73662	1	0.32547	1
6q gain	27 (48%)	29	0.21032	1	0.20659	1	0.22272	1	0.16607	1	1	1	0.18779	1	0.65066	1	0.13599	1
7p gain	21 (38%)	35	0.2001	1	0.55435	1	0.15022	1	0.2798	1	0.59219	1	0.12848	1	0.33026	1	0.12109	1
7q gain	17 (30%)	39	0.58465	1	0.8387	1	0.34125	1	0.81171	1	0.74327	1	0.16545	1	1	1	0.15484	1
8p gain	19 (34%)	37	0.18661	1	0.74402	1	0.44236	1	0.87524	1	0.97071	1	0.56059	1	0.66317	1	0.59566	1
8q gain	30 (54%)	26	0.01394	1	0.19919	1	0.050189	1	0.5058	1	0.21619	1	0.32684	1	0.067069	1	0.12189	1
9p gain	6 (11%)	50	0.35171	1	0.70521	1	0.93631	1	0.66554	1	0.83079	1	0.80548	1	0.86027	1	1	1
10p gain	21 (38%)	35	0.32786	1	0.02094	1	0.03957	1	0.11945	1	0.32448	1	0.10652	1	0.67576	1	0.19764	1
10q gain	17 (30%)	39	0.87416	1	0.33889	1	0.55363	1	0.04801	1	0.22193	1	0.18394	1	0.38124	1	0.072899	1
11p gain	5 (9%)	51	0.72209	1	0.44562	1	0.26469	1	0.85164	1	0.49414	1	0.11766	1	0.52183	1	0.092849	1
11q gain	7 (12%)	49	0.68371	1	0.38484	1	0.22938	1	0.38379	1	0.75513	1	0.03506	1	0.5755	1	0.03021	1
12p gain	22 (39%)	34	0.26514	1	0.00378	1	0.37385	1	0.04239	1	0.81013	1	0.97611	1	0.53128	1	0.62552	1
12q gain	11 (20%)	45	0.53789	1	0.53463	1	0.80827	1	0.52346	1	1	1	0.29647	1	0.91005	1	0.27316	1
13q gain	15 (27%)	41	0.64631	1	0.070749	1	0.02184	1	0.02405	1	0.22223	1	0.0456	1	0.01038	1	0.14045	1
14q gain	7 (12%)	49	0.60877	1	0.57601	1	0.25908	1	0.2578	1	0.20871	1	0.73308	1	0.22598	1	0.47544	1
15q gain	4 (7%)	52	0.18904	1	0.25557	1	0.57739	1	0.32369	1	0.75696	1	0.34764	1	0.42333	1	0.35879	1
16p gain	10 (18%)	46	0.11116	1	0.27929	1	0.19693	1	0.27647	1	1	1	0.4828	1	0.90354	1	0.40543	1
16q gain	6 (11%)	50	0.17143	1	0.84909	1	0.54538	1	0.96811	1	0.7707	1	0.92507	1	0.47781	1	0.86832	1
17p gain	9 (16%)	47	0.38529	1	0.89803	1	0.5666	1	0.56151	1	0.2858	1	0.058719	1	0.1276	1	0.17288	1
17q gain	18 (32%)	38	0.42576	1	0.26946	1	0.70098	1	0.51466	1	0.39592	1	0.30131	1	0.75862	1	0.43335	1
18p gain	18 (32%)	38	0.67607	1	0.04956	1	0.093799	1	0.34395	1	0.14723	1	0.20037	1	0.40908	1	0.43342	1
18q gain	14 (25%)	42	0.68726	1	0.081439	1	0.15202	1	0.23978	1	0.20252	1	0.087499	1	0.13956	1	0.16909	1
19p gain	24 (43%)	32	0.11588	1	0.17832	1	0.27085	1	0.36902	1	0.53316	1	0.22901	1	0.4195	1	0.51141	1
19q gain	28 (50%)	28	0.12494	1	0.075969	1	0.37762	1	0.39722	1	0.92857	1	0.89864	1	0.88469	1	0.93798	1
20p gain	37 (66%)	19	0.2883	1	0.5036	1	0.92272	1	0.76124	1	0.8741	1	0.6983	1	0.2232	1	0.47081	1
20q gain	44 (79%)	12	0.052809	1	0.91745	1	0.96835	1	0.99656	1	0.58809	1	0.5763	1	0.2138	1	0.67944	1
21q gain	18 (32%)	38	0.074089	1	0.37752	1	0.90169	1	0.89217	1	0.91464	1	0.57322	1	1	1	0.9487	1
22q gain	8 (14%)	48	0.71185	1	0.95893	1	0.80306	1	0.92525	1	0.88847	1	0.942	1	1	1	1	1
xq gain	14 (25%)	42	0.8605	1	0.42548	1	0.88116	1	0.82175	1	0.96116	1	0.5808	1	1	1	0.23805	1
1p loss	9 (16%)	47	0.59463	1	0.60366	1	0.92133	1	0.11889	1	0.11128	1	0.03077	1	0.054749	1	0.04748	1
1q loss	9 (16%)	47	0.48154	1	0.51584	1	0.51475	1	0.078519	1	0.42185	1	0.15503	1	0.21234	1	0.14347	1
3p loss	20 (36%)	36	0.01065	1	0.42258	1	0.04997	1	0.22913	1	0.37549	1	0.92804	1	0.41829	1	0.43257	1
3q loss	14 (25%)	42	0.13989	1	0.46018	1	0.13665	1	0.60601	1	0.52873	1	0.88036	1	0.38115	1	1	1
4p loss	31 (55%)	25	0.065399	1	0.062419	1	0.25685	1	0.20288	1	0.03804	1	0.71129	1	0.14576	1	0.44749	1
4q loss	33 (59%)	23	0.18615	1	0.01849	1	0.00495	1	0.03976	1	0.00015	0.0924	0.2484	1	0.01981	1	0.13644	1
5p loss	9 (16%)	47	0.9004	1	0.47497	1	0.8847	1	0.13651	1	1	1	0.29912	1	1	1	0.41644	1
5q loss	18 (32%)	38	0.76721	1	0.30322	1	0.26541	1	0.23517	1	0.35997	1	0.9476	1	0.35668	1	0.94738	1
6p loss	5 (9%)	51	0.42354	1	0.95623	1	0.75576	1	0.95673	1	0.54185	1	0.91104	1	1	1	1	1
6q loss	7 (12%)	49	0.064079	1	0.69976	1	0.64048	1	0.90086	1	0.7053	1	0.61932	1	0.67116	1	0.61436	1
7p loss	13 (23%)	43	1	1	0.6656	1	0.73791	1	0.50277	1	0.31513	1	0.45216	1	0.77905	1	0.60133	1
7q loss	13 (23%)	43	0.11953	1	0.85381	1	0.92193	1	0.82473	1	0.71744	1	0.22214	1	1	1	0.53146	1
8p loss	23 (41%)	33	0.28673	1	0.98096	1	0.82594	1	0.74355	1	0.68658	1	0.51233	1	0.60566	1	0.57839	1
8q loss	9 (16%)	47	1	1	0.75838	1	0.29488	1	0.71378	1	0.95063	1	0.75737	1	0.25987	1	0.66611	1
9p loss	34 (61%)	22	0.29676	1	0.0073599	1	0.67424	1	0.13549	1	0.86277	1	0.29048	1	1	1	0.059399	1
9q loss	39 (70%)	17	0.1922	1	0.00152	0.933	0.49444	1	0.03785	1	0.66616	1	0.11877	1	1	1	0.15641	1
10p loss	23 (41%)	33	0.62217	1	0.0127	1	0.02878	1	0.18295	1	0.24656	1	0.78867	1	0.88064	1	0.89475	1
10q loss	21 (38%)	35	0.88831	1	0.30034	1	0.17657	1	0.17084	1	0.12491	1	0.47202	1	0.39835	1	0.74055	1
11p loss	26 (46%)	30	1	1	0.00377	1	0.37722	1	0.51734	1	0.26928	1	0.57743	1	0.50902	1	0.3588	1
11q loss	24 (43%)	32	0.62488	1	0.0076899	1	0.80616	1	0.89493	1	0.29517	1	0.59178	1	0.22139	1	0.18355	1
12p loss	13 (23%)	43	0.30352	1	0.27509	1	0.5792	1	0.73269	1	0.54608	1	0.58161	1	1	1	0.21648	1
12q loss	14 (25%)	42	0.42905	1	0.87998	1	0.82126	1	0.91718	1	0.96366	1	0.90697	1	0.92101	1	0.60499	1
13q loss	26 (46%)	30	0.41801	1	0.00115	0.707	0.055999	1	0.0279	1	0.35237	1	0.12324	1	0.03971	1	0.19691	1
14q loss	27 (48%)	29	0.94278	1	0.092629	1	0.12194	1	0.12317	1	0.61665	1	0.89708	1	0.9395	1	0.93616	1
15q loss	32 (57%)	24	0.0060799	1	0.71242	1	0.92903	1	0.98147	1	0.93008	1	0.97812	1	1	1	0.89595	1
16p loss	32 (57%)	24	0.24075	1	0.49309	1	0.34284	1	0.099919	1	0.81134	1	0.91247	1	0.46992	1	0.89346	1
16q loss	37 (66%)	19	0.77737	1	0.79299	1	0.44722	1	0.091039	1	0.68347	1	0.92303	1	0.13899	1	0.856	1
17p loss	34 (61%)	22	0.54879	1	0.28569	1	0.98094	1	0.75694	1	0.80411	1	0.88958	1	0.23612	1	0.88963	1
17q loss	17 (30%)	39	0.16289	1	0.35984	1	0.71431	1	0.38086	1	0.96657	1	0.21218	1	0.93213	1	0.27717	1
18p loss	18 (32%)	38	0.03231	1	0.01691	1	0.055639	1	0.091649	1	0.066009	1	0.078359	1	0.060599	1	0.04693	1
18q loss	20 (36%)	36	0.11936	1	0.070339	1	0.18343	1	0.11913	1	0.01237	1	0.0057699	1	0.0059399	1	0.00227	1
19p loss	15 (27%)	41	0.56103	1	0.4607	1	0.20284	1	0.35651	1	0.35108	1	0.7151	1	0.21322	1	0.70427	1
19q loss	13 (23%)	43	0.73168	1	0.15331	1	0.94588	1	0.61492	1	0.22993	1	0.87245	1	0.23673	1	1	1
20p loss	7 (12%)	49	0.53551	1	0.20466	1	0.083829	1	0.073229	1	0.61829	1	0.69277	1	0.57776	1	0.69337	1
20q loss	4 (7%)	52	0.37208	1	0.60412	1	0.11662	1	0.47311	1	1	1	0.8864	1	0.67012	1	0.78949	1
21q loss	17 (30%)	39	0.67043	1	0.17851	1	0.63472	1	0.7455	1	0.67936	1	0.97159	1	0.93169	1	0.94338	1
22q loss	33 (59%)	23	0.17698	1	0.97059	1	0.96274	1	0.90199	1	0.70657	1	0.29007	1	0.46663	1	0.75944	1
xq loss	19 (34%)	37	0.7783	1	0.32762	1	0.32442	1	0.87367	1	0.52769	1	0.97226	1	0.5832	1	0.9263	1