Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1q22 42 (75%) 14 0.5054 1 0.22366 1 0.47673 1 0.29437 1 0.18514 1 0.18717 1 0.33283 1 0.2666 1 amp_2p14 28 (50%) 28 0.56048 1 0.02514 1 0.0073599 1 0.081379 1 0.48882 1 0.24805 1 0.22343 1 0.36042 1 amp_2q13 29 (52%) 27 0.53166 1 0.01561 1 0.04653 1 0.31799 1 1 1 0.66367 1 0.73812 1 0.7287 1 amp_3p25.1 20 (36%) 36 0.01228 1 0.51494 1 0.29973 1 0.11246 1 0.22816 1 0.065179 1 0.12186 1 0.066329 1 amp_3q26.2 37 (66%) 19 0.0051499 1 0.00499 1 0.090759 1 0.15758 1 0.349 1 0.24103 1 0.4617 1 0.18348 1 amp_4p16.3 25 (45%) 31 0.02741 1 0.13031 1 0.39049 1 0.18736 1 0.97506 1 0.28757 1 0.50549 1 0.53101 1 amp_5p13.2 26 (46%) 30 0.00172 0.831 0.56839 1 0.24489 1 0.056879 1 0.92833 1 0.04578 1 0.47801 1 0.17288 1 amp_6p24.2 37 (66%) 19 0.1087 1 0.97166 1 0.68764 1 0.3567 1 0.87696 1 0.49817 1 0.87537 1 0.76994 1 amp_8p11.21 33 (59%) 23 0.5508 1 0.62514 1 0.67917 1 0.55652 1 0.6242 1 1 1 0.7793 1 0.59823 1 amp_8q11.23 38 (68%) 18 0.01262 1 0.22668 1 0.19942 1 0.16818 1 0.77146 1 0.92193 1 0.62102 1 0.85749 1 amp_8q24.21 42 (75%) 14 0.00206 0.991 0.75686 1 0.1901 1 0.33933 1 0.03891 1 0.03077 1 0.0059399 1 0.01498 1 amp_8q24.21 40 (71%) 16 0.00052999 0.258 0.3573 1 0.076709 1 0.11752 1 0.04742 1 0.063359 1 0.0076999 1 0.02198 1 amp_10q22.2 26 (46%) 30 0.31184 1 0.48585 1 0.96344 1 0.92121 1 0.72532 1 0.73986 1 1 1 0.42567 1 amp_11q13.1 19 (34%) 37 0.77693 1 0.64827 1 0.32682 1 0.30575 1 0.76155 1 1 1 0.82253 1 0.9753 1 amp_12q12 22 (39%) 34 0.03097 1 0.10484 1 0.25834 1 0.40421 1 0.92632 1 1 1 0.88302 1 0.95291 1 amp_12q15 17 (30%) 39 0.58592 1 0.38099 1 0.25379 1 0.70231 1 0.80026 1 0.16689 1 1 1 0.22871 1 amp_13q31.3 25 (45%) 31 0.52526 1 0.44158 1 0.13528 1 0.11609 1 0.084389 1 0.03713 1 0.00244 1 0.053939 1 amp_16p11.2 20 (36%) 36 0.02782 1 0.28295 1 0.6524 1 0.074459 1 0.7594 1 0.40851 1 0.51499 1 0.2089 1 amp_17q12 27 (48%) 29 0.44502 1 0.19015 1 0.33269 1 0.46028 1 0.34291 1 0.78332 1 0.60791 1 1 1 amp_17q25.1 32 (57%) 24 0.49563 1 0.0123 1 0.62984 1 0.30688 1 0.68839 1 0.71705 1 0.32287 1 0.65802 1 amp_19p13.2 19 (34%) 37 0.33237 1 0.27319 1 0.7963 1 0.32278 1 0.3445 1 0.27703 1 0.14594 1 0.26717 1 amp_19q12 45 (80%) 11 0.00139 0.673 0.00013 0.0634 0.19142 1 0.01989 1 0.64221 1 0.50057 1 0.23234 1 0.43722 1 amp_20q11.21 48 (86%) 8 0.00432 1 0.16692 1 0.54554 1 0.42195 1 0.16224 1 0.14004 1 0.056559 1 0.27361 1 amp_20q11.21 48 (86%) 8 0.1016 1 0.25501 1 0.1936 1 0.31371 1 0.17765 1 0.35041 1 0.37354 1 0.55899 1 amp_xp11.21 28 (50%) 28 0.057049 1 0.56484 1 0.0471 1 0.30192 1 0.0274 1 0.10114 1 0.11327 1 0.064709 1 del_1p36.21 19 (34%) 37 0.72755 1 0.37652 1 0.34606 1 0.081659 1 0.13354 1 0.02335 1 0.071919 1 0.059789 1 del_2q22.1 11 (20%) 45 0.91744 1 0.54242 1 0.52694 1 0.17107 1 0.55193 1 0.55697 1 0.25657 1 0.9212 1 del_3p14.2 37 (66%) 19 0.73004 1 0.6995 1 0.81065 1 0.4733 1 0.62636 1 0.76629 1 0.86957 1 0.90193 1 del_3q13.31 22 (39%) 34 0.20587 1 0.04547 1 0.88039 1 0.068329 1 1 1 0.46132 1 0.35413 1 0.82097 1 del_4q22.1 37 (66%) 19 0.16399 1 0.056099 1 0.02444 1 0.15383 1 0.01262 1 0.12692 1 0.03187 1 0.057339 1 del_4q34.3 37 (66%) 19 0.0176 1 0.01983 1 0.01207 1 0.04094 1 0.00311 1 0.19891 1 0.0048 1 0.12448 1 del_5q12.1 26 (46%) 30 0.62944 1 0.092379 1 0.58667 1 0.45299 1 0.54833 1 0.29553 1 0.2548 1 0.44383 1 del_6q26 10 (18%) 46 0.41704 1 0.54397 1 0.12327 1 0.70006 1 0.33084 1 0.30122 1 0.81713 1 0.31615 1 del_7q11.22 12 (21%) 44 0.71443 1 0.50637 1 0.75975 1 0.83521 1 0.86129 1 0.53278 1 0.84052 1 0.75087 1 del_7q36.2 20 (36%) 36 0.32594 1 0.16855 1 0.49737 1 0.2765 1 0.40226 1 0.04384 1 0.32398 1 0.082249 1 del_8p23.2 33 (59%) 23 0.0018 0.868 0.42863 1 0.35217 1 0.35866 1 0.73909 1 0.32917 1 0.59768 1 0.56098 1 del_9p23 34 (61%) 22 0.29584 1 0.12207 1 0.63594 1 0.32013 1 0.50113 1 0.42506 1 0.48864 1 0.12114 1 del_9q21.13 39 (70%) 17 0.33966 1 0.32481 1 0.20891 1 0.25788 1 0.47899 1 0.3193 1 0.74424 1 0.39906 1 del_9q33.3 39 (70%) 17 0.66819 1 0.074059 1 0.11331 1 0.13954 1 0.96688 1 0.11316 1 1 1 0.26021 1 del_10q23.31 20 (36%) 36 0.15056 1 0.10586 1 0.12253 1 0.24081 1 0.76345 1 0.85274 1 0.76855 1 0.82592 1 del_11p15.5 25 (45%) 31 0.58973 1 0.7691 1 0.89928 1 0.89559 1 0.72441 1 0.89586 1 0.82755 1 0.91738 1 del_11q14.1 26 (46%) 30 0.44445 1 0.17049 1 1 1 0.92318 1 0.27001 1 0.26388 1 0.22709 1 0.073999 1 del_11q23.2 26 (46%) 30 1 1 0.11435 1 0.34338 1 0.86989 1 0.35813 1 0.85965 1 0.39681 1 0.35908 1 del_12q23.1 20 (36%) 36 0.88153 1 0.8997 1 0.65521 1 0.75345 1 0.95025 1 0.34185 1 1 1 0.5444 1 del_12q24.31 20 (36%) 36 0.44336 1 0.82437 1 0.15431 1 0.25875 1 0.56139 1 0.88908 1 0.36829 1 0.93111 1 del_13q12.11 30 (54%) 26 0.29426 1 0.01972 1 0.37452 1 0.20772 1 0.72661 1 0.02544 1 0.34584 1 0.062929 1 del_13q14.2 32 (57%) 24 0.43615 1 0.00041 0.2 0.0129 1 0.02013 1 0.48014 1 0.1585 1 0.04643 1 0.19347 1 del_14q21.1 28 (50%) 28 0.89131 1 0.050789 1 0.063479 1 0.055429 1 0.37758 1 0.38385 1 0.83499 1 0.36538 1 del_15q11.2 41 (73%) 15 0.74756 1 0.096949 1 0.55243 1 0.62203 1 0.14312 1 0.90818 1 0.32472 1 0.7054 1 del_15q15.1 43 (77%) 13 0.16542 1 0.03078 1 0.34802 1 0.76839 1 0.11972 1 0.34894 1 0.066789 1 0.20846 1 del_16p13.3 33 (59%) 23 0.66307 1 0.55002 1 0.57204 1 0.22788 1 0.34963 1 0.39062 1 0.38268 1 0.71596 1 del_16q23.1 39 (70%) 17 0.62625 1 0.42439 1 0.39647 1 0.39357 1 0.86377 1 0.81209 1 0.17112 1 0.62152 1 del_17p13.1 42 (75%) 14 0.13935 1 0.055259 1 0.056829 1 0.41989 1 0.13294 1 0.18306 1 0.01979 1 0.085419 1 del_17q21.32 19 (34%) 37 0.14788 1 0.76419 1 0.17917 1 0.067469 1 0.22308 1 0.2118 1 0.38725 1 0.7371 1 del_18q22.2 26 (46%) 30 0.33192 1 0.34104 1 0.50489 1 0.36073 1 0.02148 1 0.077669 1 0.01339 1 0.02402 1 del_19p13.3 47 (84%) 9 0.061319 1 0.02026 1 0.097339 1 0.37568 1 0.0148 1 0.085469 1 0.0093999 1 0.1125 1 del_19q13.33 17 (30%) 39 0.3158 1 0.0090599 1 0.00065999 0.32 0.03456 1 0.22195 1 0.03838 1 0.36836 1 0.01282 1 del_20p12.1 9 (16%) 47 0.53789 1 0.70302 1 0.39087 1 0.52632 1 0.21937 1 0.34092 1 0.36616 1 0.46613 1 del_22q13.31 40 (71%) 16 0.29767 1 0.4097 1 0.89379 1 0.46062 1 0.58018 1 0.35148 1 0.85841 1 0.5886 1 del_xp21.1 18 (32%) 38 0.93682 1 0.42128 1 0.81921 1 0.86815 1 0.36052 1 1 1 1 1 0.90022 1 del_xq25 23 (41%) 33 0.62602 1 0.31024 1 0.11375 1 0.89794 1 0.72975 1 0.56792 1 0.27945 1 0.38379 1