Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 51 (89%) 6 0.57003 1 0.62764 1 0.87844 1 0.51517 1 1 1 0.91152 1 1 1 1 1 FBXW7 22 (39%) 35 0.26228 1 0.72432 1 0.63332 1 0.10328 1 0.46685 1 0.93049 1 1 1 0.77367 1 PPP2R1A 16 (28%) 41 0.75896 1 0.71037 1 0.59144 1 0.67166 1 0.56366 1 0.31358 1 0.69782 1 0.23756 1 PTEN 11 (19%) 46 0.094759 1 5e-05 0.0052 0.0024 0.247 0.04571 1 0.093369 1 0.062199 1 0.00335 0.342 0.01376 1 KRAS 7 (12%) 50 0.103 1 0.01411 1 0.03157 1 0.0062499 0.625 0.4609 1 0.090459 1 0.3085 1 0.058229 1 ZBTB7B 6 (11%) 51 0.7235 1 0.93937 1 1 1 0.91406 1 0.098969 1 0.14487 1 0.47979 1 0.16393 1 CHD4 10 (18%) 47 0.346 1 0.01045 1 0.18353 1 0.0058999 0.596 0.48242 1 0.41237 1 0.089749 1 0.21444 1 PIK3R1 6 (11%) 51 1 1 0.93957 1 0.54501 1 0.70244 1 0.42749 1 0.50761 1 1 1 0.305 1 ARHGAP35 6 (11%) 51 0.56655 1 0.33173 1 1 1 0.40076 1 1 1 0.19197 1 1 1 0.17522 1 PIK3CA 20 (35%) 37 0.63589 1 0.90237 1 0.36203 1 0.37075 1 0.11132 1 0.34054 1 0.19255 1 0.26926 1 MAMLD1 4 (7%) 53 1 1 0.90265 1 0.68731 1 0.77112 1 0.066859 1 0.67733 1 0.15481 1 0.35802 1 RB1 6 (11%) 51 0.22852 1 0.091749 1 0.079789 1 0.098369 1 0.83383 1 0.86139 1 0.86486 1 1 1 LYPLA2 3 (5%) 54 0.76983 1 0.61726 1 0.6784 1 0.34626 1 0.37889 1 0.56398 1 1 1 0.69382 1