Correlation between gene mutation status and molecular subtypes

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 119 genes and 10 molecular subtypes across 62 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

No gene mutations related to molecuar subtypes.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 119 genes and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
ZFPM1	24 (39%)	38	0.804 (1.00)	0.816 (1.00)	0.718 (1.00)	0.873 (1.00)	0.376 (1.00)	0.747 (1.00)	0.823 (1.00)	0.921 (1.00)	0.381 (1.00)	0.741 (1.00)
LACTB	19 (31%)	43	0.439 (1.00)	0.687 (1.00)	0.686 (1.00)	0.564 (1.00)	1 (1.00)	0.317 (1.00)	0.377 (1.00)	0.75 (1.00)	0.322 (1.00)	0.178 (1.00)
CCDC102A	17 (27%)	45	0.0186 (1.00)	0.934 (1.00)	0.67 (1.00)	0.506 (1.00)	0.974 (1.00)	0.825 (1.00)	0.498 (1.00)	0.469 (1.00)	0.808 (1.00)	0.507 (1.00)
ZNF517	13 (21%)	49	0.164 (1.00)	0.981 (1.00)	1 (1.00)		0.822 (1.00)	0.951 (1.00)	0.173 (1.00)	0.694 (1.00)	0.727 (1.00)	0.775 (1.00)
MAL2	11 (18%)	51	0.495 (1.00)	0.313 (1.00)	1 (1.00)	1 (1.00)	0.251 (1.00)	0.51 (1.00)	0.219 (1.00)	0.267 (1.00)	1 (1.00)	0.869 (1.00)
CLDN23	10 (16%)	52	0.571 (1.00)	0.25 (1.00)	1 (1.00)	0.351 (1.00)	0.029 (1.00)	0.211 (1.00)	0.0977 (1.00)	0.182 (1.00)	0.414 (1.00)	0.545 (1.00)
TOR3A	12 (19%)	50	0.612 (1.00)	0.0137 (1.00)	0.153 (1.00)	0.316 (1.00)	0.674 (1.00)	0.00482 (1.00)	1 (1.00)	0.842 (1.00)	0.911 (1.00)	0.806 (1.00)
USP42	15 (24%)	47	0.549 (1.00)	0.0451 (1.00)	0.396 (1.00)	0.466 (1.00)	1 (1.00)	0.96 (1.00)	0.458 (1.00)	0.874 (1.00)	0.913 (1.00)	0.902 (1.00)
TP53	12 (19%)	50	0.135 (1.00)	0.789 (1.00)	0.396 (1.00)	0.467 (1.00)	0.0203 (1.00)	0.665 (1.00)	0.0162 (1.00)	0.672 (1.00)	0.0066 (1.00)	0.18 (1.00)
APOE	7 (11%)	55	1 (1.00)	0.598 (1.00)	1 (1.00)	0.381 (1.00)	0.0583 (1.00)	0.398 (1.00)	0.194 (1.00)	0.791 (1.00)	0.417 (1.00)	1 (1.00)
ZAR1	11 (18%)	51	0.647 (1.00)	0.667 (1.00)	1 (1.00)	0.793 (1.00)	0.622 (1.00)	0.868 (1.00)	0.714 (1.00)	0.971 (1.00)	1 (1.00)	0.603 (1.00)
ASPDH	8 (13%)	54	0.3 (1.00)	0.691 (1.00)	1 (1.00)	0.315 (1.00)	0.0225 (1.00)	0.393 (1.00)	0.473 (1.00)	0.0305 (1.00)	0.212 (1.00)	0.0818 (1.00)
KCNK17	9 (15%)	53	0.204 (1.00)	0.0403 (1.00)	0.0178 (1.00)	0.441 (1.00)	0.105 (1.00)	0.0088 (1.00)	0.891 (1.00)	0.546 (1.00)	0.718 (1.00)	0.446 (1.00)
LZTR1	6 (10%)	56	0.0511 (1.00)	0.85 (1.00)	1 (1.00)		0.0884 (1.00)	0.118 (1.00)	0.399 (1.00)	0.0148 (1.00)	1 (1.00)	0.455 (1.00)
ERCC2	10 (16%)	52	1 (1.00)	0.229 (1.00)	0.0377 (1.00)	0.234 (1.00)	0.479 (1.00)	0.169 (1.00)	0.597 (1.00)	0.27 (1.00)	0.336 (1.00)	0.208 (1.00)
RINL	8 (13%)	54	0.34 (1.00)	0.677 (1.00)	1 (1.00)	0.58 (1.00)	0.468 (1.00)	0.276 (1.00)	0.759 (1.00)	0.172 (1.00)	0.35 (1.00)	0.748 (1.00)
SYT8	8 (13%)	54	0.442 (1.00)	0.44 (1.00)	1 (1.00)	1 (1.00)	0.0412 (1.00)	0.177 (1.00)	1 (1.00)	0.185 (1.00)	0.75 (1.00)	0.495 (1.00)
LRIG1	16 (26%)	46	0.539 (1.00)	0.959 (1.00)	1 (1.00)	1 (1.00)	0.865 (1.00)	0.612 (1.00)	0.36 (1.00)	0.434 (1.00)	0.576 (1.00)	0.903 (1.00)
C1ORF106	9 (15%)	53	0.841 (1.00)	0.471 (1.00)	0.639 (1.00)	0.0475 (1.00)	0.343 (1.00)	0.76 (1.00)	0.474 (1.00)	0.694 (1.00)	0.0536 (1.00)	1 (1.00)
GPRIN2	8 (13%)	54	0.868 (1.00)	0.384 (1.00)	1 (1.00)	0.693 (1.00)	0.682 (1.00)	0.4 (1.00)	0.58 (1.00)	0.753 (1.00)	0.599 (1.00)	0.181 (1.00)
CTNNB1	7 (11%)	55	0.733 (1.00)	0.184 (1.00)	1 (1.00)	0.394 (1.00)	0.0182 (1.00)	0.0232 (1.00)	0.00076 (0.452)	0.178 (1.00)	0.122 (1.00)	0.712 (1.00)
C16ORF3	5 (8%)	57	0.858 (1.00)	0.00067 (0.452)	1 (1.00)	0.79 (1.00)	0.803 (1.00)	0.813 (1.00)	0.581 (1.00)	1 (1.00)	0.726 (1.00)	0.836 (1.00)
CCDC105	6 (10%)	56	1 (1.00)	0.0109 (1.00)	0.226 (1.00)	0.674 (1.00)	0.938 (1.00)	0.794 (1.00)	1 (1.00)	0.0541 (1.00)	0.218 (1.00)	0.207 (1.00)
RGS9BP	8 (13%)	54	0.726 (1.00)	0.634 (1.00)	1 (1.00)	0.13 (1.00)	1 (1.00)	0.933 (1.00)	0.218 (1.00)	0.962 (1.00)	0.343 (1.00)	0.749 (1.00)
HHIPL1	6 (10%)	56	0.274 (1.00)	0.433 (1.00)	0.484 (1.00)		0.626 (1.00)	0.517 (1.00)	0.204 (1.00)	0.425 (1.00)	0.203 (1.00)	0.333 (1.00)
C10ORF95	6 (10%)	56	0.199 (1.00)	0.379 (1.00)	1 (1.00)		0.515 (1.00)	1 (1.00)	0.486 (1.00)	0.361 (1.00)	1 (1.00)	1 (1.00)
TSC22D2	8 (13%)	54	0.947 (1.00)	0.543 (1.00)	1 (1.00)	0.954 (1.00)	0.782 (1.00)	0.817 (1.00)	0.76 (1.00)	0.432 (1.00)	0.348 (1.00)	1 (1.00)
NOXA1	5 (8%)	57	0.141 (1.00)	0.515 (1.00)	1 (1.00)		0.222 (1.00)	0.441 (1.00)	0.295 (1.00)	0.35 (1.00)	0.254 (1.00)	0.72 (1.00)
THEM4	5 (8%)	57	0.28 (1.00)	0.769 (1.00)	1 (1.00)		0.438 (1.00)	0.876 (1.00)	0.178 (1.00)	0.106 (1.00)	0.229 (1.00)	0.259 (1.00)
ATXN1	10 (16%)	52	0.552 (1.00)	0.139 (1.00)	0.6 (1.00)	0.915 (1.00)	0.24 (1.00)	0.658 (1.00)	0.287 (1.00)	0.872 (1.00)	0.235 (1.00)	0.316 (1.00)
PLIN5	5 (8%)	57	0.501 (1.00)	0.696 (1.00)	1 (1.00)	0.381 (1.00)	0.8 (1.00)	0.665 (1.00)	0.269 (1.00)	0.269 (1.00)	0.511 (1.00)	0.048 (1.00)
OPRD1	12 (19%)	50	0.967 (1.00)	0.436 (1.00)	0.655 (1.00)	0.485 (1.00)	0.8 (1.00)	0.96 (1.00)	0.296 (1.00)	0.614 (1.00)	1 (1.00)	0.512 (1.00)
KRTAP4-5	5 (8%)	57	0.632 (1.00)	0.289 (1.00)	0.484 (1.00)		0.91 (1.00)	0.877 (1.00)	1 (1.00)	0.842 (1.00)	0.436 (1.00)	1 (1.00)
C19ORF10	7 (11%)	55	0.781 (1.00)	0.424 (1.00)	0.6 (1.00)	0.393 (1.00)	0.24 (1.00)	0.123 (1.00)	0.551 (1.00)	0.861 (1.00)	0.638 (1.00)	0.712 (1.00)
AATK	6 (10%)	56	0.14 (1.00)	0.329 (1.00)	1 (1.00)		0.437 (1.00)	0.353 (1.00)	1 (1.00)	0.545 (1.00)	1 (1.00)	0.618 (1.00)
SARM1	6 (10%)	56	0.209 (1.00)	0.423 (1.00)	0.6 (1.00)	0.694 (1.00)	0.176 (1.00)	0.114 (1.00)	0.269 (1.00)	0.837 (1.00)	0.51 (1.00)	0.08 (1.00)
TRIOBP	10 (16%)	52	0.621 (1.00)	0.23 (1.00)	0.583 (1.00)	0.129 (1.00)	1 (1.00)	0.11 (1.00)	0.711 (1.00)	0.871 (1.00)	1 (1.00)	0.774 (1.00)
ZNF598	12 (19%)	50	0.11 (1.00)	0.314 (1.00)	1 (1.00)	0.747 (1.00)	0.49 (1.00)	0.951 (1.00)	1 (1.00)	0.226 (1.00)	0.902 (1.00)	1 (1.00)
WDR34	5 (8%)	57	0.63 (1.00)	0.829 (1.00)	0.484 (1.00)		0.865 (1.00)	0.814 (1.00)	0.843 (1.00)	0.548 (1.00)	0.842 (1.00)	0.333 (1.00)
ZNF628	7 (11%)	55	0.21 (1.00)	0.927 (1.00)	1 (1.00)	0.676 (1.00)	0.312 (1.00)	0.116 (1.00)	0.093 (1.00)	0.5 (1.00)	0.283 (1.00)	0.545 (1.00)
BTBD11	6 (10%)	56	1 (1.00)	0.312 (1.00)	1 (1.00)		0.481 (1.00)	1 (1.00)	0.49 (1.00)	0.184 (1.00)	0.724 (1.00)	0.336 (1.00)
IRX3	5 (8%)	57	0.142 (1.00)	0.711 (1.00)	0.484 (1.00)		0.521 (1.00)	0.118 (1.00)	0.177 (1.00)	0.778 (1.00)	0.23 (1.00)	0.455 (1.00)
FPGS	5 (8%)	57	1 (1.00)	1 (1.00)	1 (1.00)	0.351 (1.00)	0.665 (1.00)	0.6 (1.00)	0.0568 (1.00)	0.622 (1.00)	0.825 (1.00)	0.615 (1.00)
MEN1	5 (8%)	57	0.42 (1.00)	0.0472 (1.00)	0.484 (1.00)		0.0128 (1.00)	0.00638 (1.00)	0.203 (1.00)	0.0426 (1.00)	0.134 (1.00)	0.204 (1.00)
BHLHE22	5 (8%)	57	0.423 (1.00)	0.0735 (1.00)	1 (1.00)	0.915 (1.00)	0.119 (1.00)	0.815 (1.00)	0.582 (1.00)	0.836 (1.00)	0.727 (1.00)	0.835 (1.00)
DMKN	3 (5%)	59	1 (1.00)	0.326 (1.00)	0.464 (1.00)		0.619 (1.00)	0.443 (1.00)	0.00644 (1.00)	0.567 (1.00)	0.255 (1.00)	1 (1.00)
OBSCN	18 (29%)	44	0.31 (1.00)	0.521 (1.00)	1 (1.00)	0.544 (1.00)	0.671 (1.00)	0.804 (1.00)	0.151 (1.00)	0.497 (1.00)	1 (1.00)	0.386 (1.00)
PANK2	5 (8%)	57	0.629 (1.00)	0.432 (1.00)	0.226 (1.00)	0.352 (1.00)	0.116 (1.00)	0.0513 (1.00)	0.43 (1.00)	0.348 (1.00)	1 (1.00)	0.256 (1.00)
RREB1	5 (8%)	57	0.726 (1.00)	0.852 (1.00)	0.206 (1.00)		0.62 (1.00)	1 (1.00)	0.529 (1.00)	0.546 (1.00)	0.171 (1.00)	0.353 (1.00)
RNF149	4 (6%)	58	0.34 (1.00)	0.0364 (1.00)	0.583 (1.00)	0.955 (1.00)	0.438 (1.00)	0.602 (1.00)	0.314 (1.00)	0.261 (1.00)	0.665 (1.00)	0.173 (1.00)
GLTPD2	6 (10%)	56	0.876 (1.00)	0.841 (1.00)	0.484 (1.00)		0.829 (1.00)	0.399 (1.00)	0.552 (1.00)	0.527 (1.00)	0.873 (1.00)	0.133 (1.00)
SNED1	5 (8%)	57	0.633 (1.00)	0.315 (1.00)	0.464 (1.00)		0.398 (1.00)	0.668 (1.00)	0.0941 (1.00)	0.663 (1.00)	1 (1.00)	0.544 (1.00)
TPO	12 (19%)	50	0.261 (1.00)	0.299 (1.00)	0.102 (1.00)	0.697 (1.00)	0.172 (1.00)	0.125 (1.00)	0.0981 (1.00)	0.344 (1.00)	1 (1.00)	0.173 (1.00)
PTPLA	4 (6%)	58	0.418 (1.00)	0.327 (1.00)	1 (1.00)		0.339 (1.00)	0.441 (1.00)	0.776 (1.00)	1 (1.00)	0.775 (1.00)	1 (1.00)
PRSS27	3 (5%)	59	1 (1.00)	0.908 (1.00)	1 (1.00)		0.618 (1.00)	0.0502 (1.00)	0.131 (1.00)	1 (1.00)	0.612 (1.00)	0.554 (1.00)
CD320	4 (6%)	58	1 (1.00)	0.851 (1.00)	1 (1.00)		0.739 (1.00)	0.658 (1.00)	0.4 (1.00)	0.228 (1.00)	0.232 (1.00)	0.26 (1.00)
SEMA5B	8 (13%)	54	0.339 (1.00)	0.268 (1.00)	0.311 (1.00)	0.175 (1.00)	0.4 (1.00)	0.214 (1.00)	0.647 (1.00)	0.297 (1.00)	0.359 (1.00)	0.408 (1.00)
CCDC150	4 (6%)	58	0.177 (1.00)	0.851 (1.00)	0.226 (1.00)	0.605 (1.00)	0.238 (1.00)	0.118 (1.00)	0.402 (1.00)	0.213 (1.00)	1 (1.00)	0.453 (1.00)
TAF5	4 (6%)	58	1 (1.00)	0.77 (1.00)	0.583 (1.00)	0.953 (1.00)	1 (1.00)	0.877 (1.00)	0.01 (1.00)	0.116 (1.00)	0.0566 (1.00)	0.0139 (1.00)
GARS	19 (31%)	43	0.0763 (1.00)	0.0913 (1.00)	0.228 (1.00)	0.335 (1.00)	0.342 (1.00)	0.103 (1.00)	0.116 (1.00)	0.4 (1.00)	0.214 (1.00)	0.397 (1.00)
MUC5B	22 (35%)	40	1 (1.00)	0.627 (1.00)	1 (1.00)	0.812 (1.00)	0.728 (1.00)	0.671 (1.00)	0.719 (1.00)	0.615 (1.00)	1 (1.00)	0.53 (1.00)
KIAA1984	4 (6%)	58	0.422 (1.00)	0.709 (1.00)	0.226 (1.00)	0.502 (1.00)	0.127 (1.00)	0.049 (1.00)	0.031 (1.00)	0.584 (1.00)	0.663 (1.00)	0.792 (1.00)
SRPX	3 (5%)	59	0.753 (1.00)	0.114 (1.00)	1 (1.00)		0.619 (1.00)	1 (1.00)	0.776 (1.00)	0.718 (1.00)	1 (1.00)	0.399 (1.00)
TNIP2	5 (8%)	57	0.631 (1.00)	0.707 (1.00)	1 (1.00)		0.74 (1.00)	0.877 (1.00)	1 (1.00)	0.412 (1.00)	1 (1.00)	0.453 (1.00)
IDUA	8 (13%)	54	0.38 (1.00)	0.853 (1.00)	1 (1.00)	0.793 (1.00)	0.512 (1.00)	0.549 (1.00)	0.202 (1.00)	0.432 (1.00)	0.458 (1.00)	0.648 (1.00)
RNF39	5 (8%)	57	0.724 (1.00)	0.377 (1.00)	0.6 (1.00)	0.793 (1.00)	0.175 (1.00)	0.265 (1.00)	0.158 (1.00)	0.702 (1.00)	0.24 (1.00)	0.681 (1.00)
PABPC1	4 (6%)	58	0.418 (1.00)		0.464 (1.00)
SCRT1	3 (5%)	59	1 (1.00)	0.427 (1.00)	0.464 (1.00)		0.473 (1.00)	0.616 (1.00)	0.426 (1.00)	0.794 (1.00)	0.469 (1.00)	1 (1.00)
MAP1S	5 (8%)	57	0.157 (1.00)	0.278 (1.00)	1 (1.00)	0.415 (1.00)	0.398 (1.00)	1 (1.00)	1 (1.00)	0.834 (1.00)	0.422 (1.00)	0.837 (1.00)
NF1	7 (11%)	55	0.253 (1.00)	0.903 (1.00)	0.102 (1.00)	0.394 (1.00)	0.359 (1.00)	0.188 (1.00)	0.279 (1.00)	0.883 (1.00)	1 (1.00)	0.0976 (1.00)
AKAP2	4 (6%)	58	0.107 (1.00)	0.432 (1.00)	1 (1.00)	0.675 (1.00)	0.738 (1.00)	0.173 (1.00)	0.531 (1.00)	0.442 (1.00)	0.823 (1.00)	0.352 (1.00)
NOTCH2	5 (8%)	57	0.28 (1.00)	0.896 (1.00)	1 (1.00)		0.522 (1.00)	0.117 (1.00)	0.0316 (1.00)	0.319 (1.00)	0.663 (1.00)	0.795 (1.00)
FANK1	4 (6%)	58	1 (1.00)	0.325 (1.00)	1 (1.00)		0.856 (1.00)	0.289 (1.00)	0.778 (1.00)	0.229 (1.00)	0.775 (1.00)	0.258 (1.00)
NEFH	6 (10%)	56	0.0503 (1.00)	0.173 (1.00)	0.484 (1.00)		0.114 (1.00)	0.0503 (1.00)	0.4 (1.00)	0.21 (1.00)	0.665 (1.00)	0.452 (1.00)
NPTX1	3 (5%)	59	0.64 (1.00)	1 (1.00)	0.464 (1.00)		1 (1.00)	0.816 (1.00)	0.584 (1.00)	0.792 (1.00)	0.353 (1.00)	0.556 (1.00)
KBTBD13	9 (15%)	53	0.457 (1.00)	0.115 (1.00)	0.311 (1.00)	0.792 (1.00)	0.687 (1.00)	0.118 (1.00)	1 (1.00)	0.328 (1.00)	1 (1.00)	0.601 (1.00)
RASIP1	6 (10%)	56	0.359 (1.00)	0.349 (1.00)	1 (1.00)		0.0425 (1.00)	0.187 (1.00)	0.0563 (1.00)	0.695 (1.00)	0.414 (1.00)	0.714 (1.00)
AR	4 (6%)	58	0.417 (1.00)	0.515 (1.00)	1 (1.00)	0.954 (1.00)	0.476 (1.00)	0.441 (1.00)	0.428 (1.00)	1 (1.00)	0.256 (1.00)	1 (1.00)
KNDC1	9 (15%)	53	0.354 (1.00)	0.0652 (1.00)	1 (1.00)	0.551 (1.00)	0.026 (1.00)	0.325 (1.00)	0.421 (1.00)	0.367 (1.00)	0.187 (1.00)	0.381 (1.00)
SEZ6L2	8 (13%)	54	0.382 (1.00)	0.666 (1.00)	1 (1.00)	0.788 (1.00)	0.828 (1.00)	1 (1.00)	0.462 (1.00)	0.628 (1.00)	1 (1.00)	0.848 (1.00)
VARS	6 (10%)	56	1 (1.00)	0.423 (1.00)	0.226 (1.00)	0.383 (1.00)	0.215 (1.00)	0.0665 (1.00)	0.646 (1.00)	0.863 (1.00)	0.748 (1.00)	1 (1.00)
IER5	3 (5%)	59	0.197 (1.00)		0.464 (1.00)
NMU	5 (8%)	57	0.915 (1.00)	1 (1.00)	0.464 (1.00)		0.0701 (1.00)	0.618 (1.00)	1 (1.00)	0.543 (1.00)	0.824 (1.00)	0.617 (1.00)
TMEM189	3 (5%)	59	0.198 (1.00)		0.464 (1.00)
ADAD2	4 (6%)	58	0.421 (1.00)	0.575 (1.00)	1 (1.00)		0.738 (1.00)	0.171 (1.00)	0.00898 (1.00)	0.511 (1.00)	0.0558 (1.00)	0.352 (1.00)
PLEC	13 (21%)	49	0.428 (1.00)	0.672 (1.00)	0.333 (1.00)	0.046 (1.00)	0.204 (1.00)	0.72 (1.00)	0.597 (1.00)	0.636 (1.00)	0.142 (1.00)	0.624 (1.00)
RGMB	6 (10%)	56	0.652 (1.00)		1 (1.00)
CLIC6	5 (8%)	57	0.631 (1.00)	1 (1.00)	0.206 (1.00)		0.667 (1.00)	0.118 (1.00)	0.178 (1.00)	0.581 (1.00)	0.296 (1.00)	1 (1.00)
ZNF814	3 (5%)	59	1 (1.00)		1 (1.00)
DSPP	9 (15%)	53	0.614 (1.00)	0.0612 (1.00)	1 (1.00)	0.694 (1.00)	1 (1.00)	0.481 (1.00)	0.448 (1.00)	0.536 (1.00)	0.901 (1.00)	1 (1.00)
AMDHD1	10 (16%)	52	0.656 (1.00)	0.755 (1.00)	0.226 (1.00)	0.351 (1.00)	0.585 (1.00)	0.136 (1.00)	0.174 (1.00)	0.852 (1.00)	0.904 (1.00)	0.681 (1.00)
CRIPAK	10 (16%)	52	0.385 (1.00)	0.926 (1.00)	0.6 (1.00)	0.935 (1.00)	0.49 (1.00)	0.69 (1.00)	0.893 (1.00)	0.329 (1.00)	0.476 (1.00)	0.366 (1.00)
NOM1	6 (10%)	56	1 (1.00)	0.312 (1.00)	1 (1.00)		0.865 (1.00)	1 (1.00)	1 (1.00)	0.787 (1.00)	0.42 (1.00)	1 (1.00)
MAP7	3 (5%)	59	1 (1.00)	0.648 (1.00)	0.464 (1.00)		1 (1.00)	0.814 (1.00)	0.58 (1.00)	0.793 (1.00)	1 (1.00)	0.557 (1.00)
PTX4	3 (5%)	59	1 (1.00)	1 (1.00)	1 (1.00)		0.472 (1.00)	0.195 (1.00)	0.431 (1.00)	1 (1.00)	0.253 (1.00)	0.254 (1.00)
LRP11	6 (10%)	56	1 (1.00)	0.0812 (1.00)	1 (1.00)		0.799 (1.00)	0.663 (1.00)	0.579 (1.00)	0.937 (1.00)	0.84 (1.00)	0.837 (1.00)
PDCD6	3 (5%)	59	0.302 (1.00)	0.65 (1.00)	0.464 (1.00)				1 (1.00)	0.64 (1.00)	1 (1.00)	1 (1.00)
SHOX2	3 (5%)	59	0.412 (1.00)		0.464 (1.00)
UQCRFS1	5 (8%)	57	0.75 (1.00)	0.586 (1.00)	0.484 (1.00)		1 (1.00)	0.877 (1.00)	0.486 (1.00)	0.204 (1.00)	0.843 (1.00)	0.333 (1.00)
CTBP2	3 (5%)	59	0.754 (1.00)		1 (1.00)
PRKAR1A	6 (10%)	56	0.616 (1.00)	1 (1.00)	0.6 (1.00)	0.794 (1.00)	0.279 (1.00)	0.399 (1.00)	0.104 (1.00)	0.587 (1.00)	0.0481 (1.00)	0.589 (1.00)
JMJD4	3 (5%)	59	1 (1.00)		0.484 (1.00)
HSD17B1	4 (6%)	58	0.915 (1.00)	0.0499 (1.00)	0.583 (1.00)	0.504 (1.00)	0.907 (1.00)	0.00799 (1.00)	1 (1.00)	0.842 (1.00)	0.553 (1.00)	0.794 (1.00)
COQ2	5 (8%)	57	0.362 (1.00)	0.766 (1.00)	1 (1.00)		0.441 (1.00)	0.6 (1.00)	1 (1.00)	0.673 (1.00)	0.549 (1.00)	0.62 (1.00)
FEZ2	3 (5%)	59	0.467 (1.00)	0.352 (1.00)	1 (1.00)		0.222 (1.00)	0.814 (1.00)	0.193 (1.00)	0.794 (1.00)	0.774 (1.00)	0.553 (1.00)
DLEU7	3 (5%)	59	0.528 (1.00)		1 (1.00)
RNF135	3 (5%)	59	0.754 (1.00)		0.464 (1.00)
SPIRE2	3 (5%)	59	0.299 (1.00)	0.0383 (1.00)	1 (1.00)		1 (1.00)	0.815 (1.00)	1 (1.00)	0.792 (1.00)	1 (1.00)	1 (1.00)
KRTAP5-5	3 (5%)	59	1 (1.00)
SGK223	3 (5%)	59	0.755 (1.00)		1 (1.00)
C9ORF66	5 (8%)	57	1 (1.00)	0.926 (1.00)	1 (1.00)		1 (1.00)	0.516 (1.00)	0.581 (1.00)	0.935 (1.00)	0.347 (1.00)	0.542 (1.00)
AQP7	3 (5%)	59	0.755 (1.00)
ADAMTS7	4 (6%)	58	0.2 (1.00)	0.479 (1.00)	0.0873 (1.00)	0.349 (1.00)	0.0914 (1.00)	0.437 (1.00)	0.0824 (1.00)	0.26 (1.00)	0.122 (1.00)	0.0391 (1.00)
PCDHB13	5 (8%)	57	0.393 (1.00)	0.141 (1.00)	0.484 (1.00)		0.129 (1.00)	0.355 (1.00)	0.667 (1.00)	0.0601 (1.00)	0.436 (1.00)	0.453 (1.00)
CSGALNACT2	3 (5%)	59	0.16 (1.00)	0.0383 (1.00)	0.464 (1.00)		0.773 (1.00)	0.813 (1.00)	0.58 (1.00)	0.874 (1.00)	0.349 (1.00)	0.402 (1.00)
HLA-A	3 (5%)	59	1 (1.00)	1 (1.00)	1 (1.00)		0.856 (1.00)	0.196 (1.00)	1 (1.00)	0.51 (1.00)	0.776 (1.00)	0.257 (1.00)
MTFMT	3 (5%)	59	1 (1.00)		1 (1.00)
NLRP5	4 (6%)	58	0.914 (1.00)	0.17 (1.00)	0.464 (1.00)		1 (1.00)	0.121 (1.00)	0.777 (1.00)	0.642 (1.00)	1 (1.00)	0.0772 (1.00)
KCNJ11	4 (6%)	58	0.0207 (1.00)	0.705 (1.00)	1 (1.00)		0.438 (1.00)	0.228 (1.00)	0.126 (1.00)	0.0536 (1.00)	0.29 (1.00)	0.259 (1.00)

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZFPM1 MUTATED	10	8	3	3
ZFPM1 WILD-TYPE	11	12	7	6

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZFPM1 MUTATED	6	4	4	5	2
ZFPM1 WILD-TYPE	7	4	10	8	5

'ZFPM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZFPM1 MUTATED	5	7
ZFPM1 WILD-TYPE	8	8

'ZFPM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZFPM1 MUTATED	2	4	1	1	1	1	1	1
ZFPM1 WILD-TYPE	3	2	4	2	2	0	2	1

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZFPM1 MUTATED	7	1	7	6
ZFPM1 WILD-TYPE	9	7	7	10

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZFPM1 MUTATED	8	6	1	6
ZFPM1 WILD-TYPE	8	10	3	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZFPM1 MUTATED	10	5	6
ZFPM1 WILD-TYPE	16	6	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.921 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZFPM1 MUTATED	5	8	2	5	1
ZFPM1 WILD-TYPE	8	10	6	9	1

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S9. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZFPM1 MUTATED	9	7	5
ZFPM1 WILD-TYPE	12	7	14

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S10. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZFPM1 MUTATED	12	7	2
ZFPM1 WILD-TYPE	18	9	6

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LACTB MUTATED	6	5	3	5
LACTB WILD-TYPE	15	15	7	4

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LACTB MUTATED	2	3	5	4	3
LACTB WILD-TYPE	11	5	9	9	4

'LACTB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
LACTB MUTATED	3	5
LACTB WILD-TYPE	10	10

'LACTB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LACTB MUTATED	2	1	2	0	2	0	0	1
LACTB WILD-TYPE	3	5	3	3	1	1	3	1

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LACTB MUTATED	5	2	5	5
LACTB WILD-TYPE	11	6	9	11

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LACTB MUTATED	4	5	3	5
LACTB WILD-TYPE	12	11	1	13

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S17. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LACTB MUTATED	6	5	6
LACTB WILD-TYPE	20	6	12

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S18. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LACTB MUTATED	4	5	4	4	0
LACTB WILD-TYPE	9	13	4	10	2

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S19. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LACTB MUTATED	8	2	7
LACTB WILD-TYPE	13	12	12

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S20. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LACTB MUTATED	8	4	5
LACTB WILD-TYPE	22	12	3

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0186 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC102A MUTATED	4	8	0	5
CCDC102A WILD-TYPE	17	12	10	4

Figure S1. Get High-res Image Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC102A MUTATED	3	2	4	4	3
CCDC102A WILD-TYPE	10	6	10	9	4

'CCDC102A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CCDC102A MUTATED	4	3
CCDC102A WILD-TYPE	9	12

'CCDC102A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC102A MUTATED	1	1	0	1	1	1	1	1
CCDC102A WILD-TYPE	4	5	5	2	2	0	2	1

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.974 (Fisher's exact test), Q value = 1

Table S25. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC102A MUTATED	4	3	4	5
CCDC102A WILD-TYPE	12	5	10	11

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S26. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC102A MUTATED	4	4	1	7
CCDC102A WILD-TYPE	12	12	3	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S27. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC102A MUTATED	7	2	7
CCDC102A WILD-TYPE	19	9	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S28. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC102A MUTATED	2	6	4	4	0
CCDC102A WILD-TYPE	11	12	4	10	2

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S29. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC102A MUTATED	7	3	6
CCDC102A WILD-TYPE	14	11	13

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S30. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC102A MUTATED	7	6	3
CCDC102A WILD-TYPE	23	10	5

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF517 MUTATED	7	5	0	1
ZNF517 WILD-TYPE	14	15	10	8

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.981 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF517 MUTATED	3	1	2	2	1
ZNF517 WILD-TYPE	10	7	12	11	6

'ZNF517 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S33. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZNF517 MUTATED	1	1
ZNF517 WILD-TYPE	12	14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S34. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF517 MUTATED	4	1	2	2
ZNF517 WILD-TYPE	12	7	12	14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.951 (Fisher's exact test), Q value = 1

Table S35. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF517 MUTATED	3	2	1	3
ZNF517 WILD-TYPE	13	14	3	15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S36. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF517 MUTATED	3	4	2
ZNF517 WILD-TYPE	23	7	16

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S37. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF517 MUTATED	1	3	1	4	0
ZNF517 WILD-TYPE	12	15	7	10	2

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S38. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF517 MUTATED	4	3	2
ZNF517 WILD-TYPE	17	11	17

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S39. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF517 MUTATED	5	2	2
ZNF517 WILD-TYPE	25	14	6

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAL2 MUTATED	4	5	2	0
MAL2 WILD-TYPE	17	15	8	9

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S41. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAL2 MUTATED	3	2	0	2	1
MAL2 WILD-TYPE	10	6	14	11	6

'MAL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S42. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MAL2 MUTATED	2	2
MAL2 WILD-TYPE	11	13

'MAL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S43. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAL2 MUTATED	1	1	1	1	0	0	0	0
MAL2 WILD-TYPE	4	5	4	2	3	1	3	2

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S44. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAL2 MUTATED	3	2	0	3
MAL2 WILD-TYPE	13	6	14	13

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S45. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAL2 MUTATED	4	1	0	3
MAL2 WILD-TYPE	12	15	4	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S46. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAL2 MUTATED	2	3	3
MAL2 WILD-TYPE	24	8	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S47. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAL2 MUTATED	0	3	1	4	0
MAL2 WILD-TYPE	13	15	7	10	2

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S48. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAL2 MUTATED	3	2	3
MAL2 WILD-TYPE	18	12	16

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S49. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAL2 MUTATED	4	3	1
MAL2 WILD-TYPE	26	13	7

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S50. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CLDN23 MUTATED	2	5	1	2
CLDN23 WILD-TYPE	19	15	9	7

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S51. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CLDN23 MUTATED	1	2	1	3	3
CLDN23 WILD-TYPE	12	6	13	10	4

'CLDN23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S52. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CLDN23 MUTATED	1	2
CLDN23 WILD-TYPE	12	13

'CLDN23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S53. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CLDN23 MUTATED	1	0	0	0	1	0	0	1
CLDN23 WILD-TYPE	4	6	5	3	2	1	3	1

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.029 (Fisher's exact test), Q value = 1

Table S54. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CLDN23 MUTATED	1	1	1	7
CLDN23 WILD-TYPE	15	7	13	9

Figure S2. Get High-res Image Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S55. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLDN23 MUTATED	3	1	0	6
CLDN23 WILD-TYPE	13	15	4	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0977 (Fisher's exact test), Q value = 1

Table S56. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CLDN23 MUTATED	2	2	6
CLDN23 WILD-TYPE	24	9	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S57. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLDN23 MUTATED	1	4	3	1	1
CLDN23 WILD-TYPE	12	14	5	13	1

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S58. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CLDN23 MUTATED	4	1	5
CLDN23 WILD-TYPE	17	13	14

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S59. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CLDN23 MUTATED	4	4	2
CLDN23 WILD-TYPE	26	12	6

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S60. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TOR3A MUTATED	6	3	1	1
TOR3A WILD-TYPE	15	17	9	8

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0137 (Fisher's exact test), Q value = 1

Table S61. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TOR3A MUTATED	0	0	4	6	1
TOR3A WILD-TYPE	13	8	10	7	6

Figure S3. Get High-res Image Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TOR3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 1

Table S62. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TOR3A MUTATED	4	1
TOR3A WILD-TYPE	9	14

'TOR3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S63. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TOR3A MUTATED	0	1	2	0	0	1	1	0
TOR3A WILD-TYPE	5	5	3	3	3	0	2	2

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S64. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TOR3A MUTATED	2	1	4	4
TOR3A WILD-TYPE	14	7	10	12

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00482 (Fisher's exact test), Q value = 1

Table S65. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TOR3A MUTATED	0	3	3	5
TOR3A WILD-TYPE	16	13	1	13

Figure S4. Get High-res Image Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S66. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	21	9	14

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S67. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TOR3A MUTATED	2	5	2	2	0
TOR3A WILD-TYPE	11	13	6	12	2

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S68. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	16	12	15

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S69. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TOR3A MUTATED	6	4	1
TOR3A WILD-TYPE	24	12	7

'USP42 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S70. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
USP42 MUTATED	5	4	2	4
USP42 WILD-TYPE	16	16	8	5

'USP42 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0451 (Fisher's exact test), Q value = 1

Table S71. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
USP42 MUTATED	2	4	0	3	2
USP42 WILD-TYPE	11	4	14	10	5

Figure S5. Get High-res Image Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'USP42 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S72. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
USP42 MUTATED	2	5
USP42 WILD-TYPE	11	10

'USP42 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S73. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
USP42 MUTATED	2	2	0	1	1	1	0	0
USP42 WILD-TYPE	3	4	5	2	2	0	3	2

'USP42 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S74. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
USP42 MUTATED	3	2	3	3
USP42 WILD-TYPE	13	6	11	13

'USP42 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S75. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
USP42 MUTATED	3	4	1	3
USP42 WILD-TYPE	13	12	3	15

'USP42 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S76. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
USP42 MUTATED	6	3	2
USP42 WILD-TYPE	20	8	16

'USP42 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S77. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
USP42 MUTATED	2	3	2	4	0
USP42 WILD-TYPE	11	15	6	10	2

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S78. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
USP42 MUTATED	5	2	4
USP42 WILD-TYPE	16	12	15

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S79. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
USP42 MUTATED	7	3	1
USP42 WILD-TYPE	23	13	7

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 1

Table S80. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TP53 MUTATED	5	1	3	3
TP53 WILD-TYPE	16	19	7	6

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S81. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TP53 MUTATED	2	3	3	2	1
TP53 WILD-TYPE	11	5	11	11	6

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S82. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TP53 MUTATED	2	5
TP53 WILD-TYPE	11	10

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S83. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TP53 MUTATED	3	2	0	1	0	0	1	0
TP53 WILD-TYPE	2	4	5	2	3	1	2	2

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0203 (Fisher's exact test), Q value = 1

Table S84. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TP53 MUTATED	3	2	6	0
TP53 WILD-TYPE	13	6	8	16

Figure S6. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S85. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TP53 MUTATED	4	4	1	2
TP53 WILD-TYPE	12	12	3	16

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0162 (Fisher's exact test), Q value = 1

Table S86. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TP53 MUTATED	7	4	0
TP53 WILD-TYPE	19	7	18

Figure S7. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S87. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TP53 MUTATED	4	2	2	3	0
TP53 WILD-TYPE	9	16	6	11	2

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0066 (Fisher's exact test), Q value = 1

Table S88. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TP53 MUTATED	8	3	0
TP53 WILD-TYPE	13	11	19

Figure S8. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S89. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TP53 MUTATED	9	1	1
TP53 WILD-TYPE	21	15	7

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S90. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
APOE MUTATED	3	2	1	1
APOE WILD-TYPE	18	18	9	8

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S91. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
APOE MUTATED	1	0	3	2	0
APOE WILD-TYPE	12	8	11	11	7

'APOE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S92. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
APOE MUTATED	1	2
APOE WILD-TYPE	12	13

'APOE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S93. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
APOE MUTATED	0	1	0	0	0	0	1	1
APOE WILD-TYPE	5	5	5	3	3	1	2	1

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0583 (Fisher's exact test), Q value = 1

Table S94. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
APOE MUTATED	2	0	4	0
APOE WILD-TYPE	14	8	10	16

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S95. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
APOE MUTATED	1	3	1	1
APOE WILD-TYPE	15	13	3	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S96. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
APOE MUTATED	2	3	1
APOE WILD-TYPE	24	8	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S97. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
APOE MUTATED	1	3	0	2	0
APOE WILD-TYPE	12	15	8	12	2

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S98. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
APOE MUTATED	2	3	1
APOE WILD-TYPE	19	11	18

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S99. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
APOE MUTATED	3	2	1
APOE WILD-TYPE	27	14	7

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S100. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZAR1 MUTATED	4	3	1	3
ZAR1 WILD-TYPE	17	17	9	6

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S101. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZAR1 MUTATED	3	1	1	2	2
ZAR1 WILD-TYPE	10	7	13	11	5

'ZAR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S102. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZAR1 MUTATED	2	2
ZAR1 WILD-TYPE	11	13

'ZAR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S103. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZAR1 MUTATED	0	2	1	0	1	0	0	0
ZAR1 WILD-TYPE	5	4	4	3	2	1	3	2

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S104. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZAR1 MUTATED	3	0	2	4
ZAR1 WILD-TYPE	13	8	12	12

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S105. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZAR1 MUTATED	3	2	0	4
ZAR1 WILD-TYPE	13	14	4	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S106. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZAR1 MUTATED	4	1	4
ZAR1 WILD-TYPE	22	10	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S107. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZAR1 MUTATED	2	4	1	2	0
ZAR1 WILD-TYPE	11	14	7	12	2

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S108. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZAR1 MUTATED	4	2	3
ZAR1 WILD-TYPE	17	12	16

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S109. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZAR1 MUTATED	4	4	1
ZAR1 WILD-TYPE	26	12	7

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S110. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ASPDH MUTATED	3	2	3	0
ASPDH WILD-TYPE	18	18	7	9

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S111. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ASPDH MUTATED	3	1	3	1	0
ASPDH WILD-TYPE	10	7	11	12	7

'ASPDH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S112. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ASPDH MUTATED	2	3
ASPDH WILD-TYPE	11	12

'ASPDH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S113. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ASPDH MUTATED	0	3	0	1	0	0	1	0
ASPDH WILD-TYPE	5	3	5	2	3	1	2	2

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0225 (Fisher's exact test), Q value = 1

Table S114. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ASPDH MUTATED	3	0	5	0
ASPDH WILD-TYPE	13	8	9	16

Figure S9. Get High-res Image Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S115. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ASPDH MUTATED	3	4	0	1
ASPDH WILD-TYPE	13	12	4	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S116. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ASPDH MUTATED	5	2	1
ASPDH WILD-TYPE	21	9	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0305 (Fisher's exact test), Q value = 1

Table S117. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ASPDH MUTATED	4	0	0	4	0
ASPDH WILD-TYPE	9	18	8	10	2

Figure S10. Get High-res Image Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S118. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ASPDH MUTATED	3	4	1
ASPDH WILD-TYPE	18	10	18

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0818 (Fisher's exact test), Q value = 1

Table S119. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ASPDH MUTATED	7	0	1
ASPDH WILD-TYPE	23	16	7

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S120. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KCNK17 MUTATED	3	1	2	3
KCNK17 WILD-TYPE	18	19	8	6

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0403 (Fisher's exact test), Q value = 1

Table S121. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KCNK17 MUTATED	0	2	5	1	0
KCNK17 WILD-TYPE	13	6	9	12	7

Figure S11. Get High-res Image Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KCNK17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0178 (Fisher's exact test), Q value = 1

Table S122. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KCNK17 MUTATED	0	6
KCNK17 WILD-TYPE	13	9

Figure S12. Get High-res Image Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'KCNK17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S123. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KCNK17 MUTATED	1	3	0	0	1	0	0	1
KCNK17 WILD-TYPE	4	3	5	3	2	1	3	1

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S124. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KCNK17 MUTATED	1	1	5	1
KCNK17 WILD-TYPE	15	7	9	15

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0088 (Fisher's exact test), Q value = 1

Table S125. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KCNK17 MUTATED	0	6	1	1
KCNK17 WILD-TYPE	16	10	3	17

Figure S13. Get High-res Image Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S126. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KCNK17 MUTATED	4	2	2
KCNK17 WILD-TYPE	22	9	16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S127. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KCNK17 MUTATED	3	1	2	2	0
KCNK17 WILD-TYPE	10	17	6	12	2

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S128. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KCNK17 MUTATED	4	1	3
KCNK17 WILD-TYPE	17	13	16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S129. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KCNK17 MUTATED	5	1	2
KCNK17 WILD-TYPE	25	15	6

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0511 (Fisher's exact test), Q value = 1

Table S130. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LZTR1 MUTATED	5	0	1	0
LZTR1 WILD-TYPE	16	20	9	9

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S131. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LZTR1 MUTATED	2	0	1	1	0
LZTR1 WILD-TYPE	11	8	13	12	7

'LZTR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S132. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
LZTR1 MUTATED	0	1
LZTR1 WILD-TYPE	13	14

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0884 (Fisher's exact test), Q value = 1

Table S133. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LZTR1 MUTATED	3	1	0	0
LZTR1 WILD-TYPE	13	7	14	16

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S134. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LZTR1 MUTATED	2	1	1	0
LZTR1 WILD-TYPE	14	15	3	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S135. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LZTR1 MUTATED	3	1	0
LZTR1 WILD-TYPE	23	10	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0148 (Fisher's exact test), Q value = 1

Table S136. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LZTR1 MUTATED	0	0	0	3	1
LZTR1 WILD-TYPE	13	18	8	11	1

Figure S14. Get High-res Image Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S137. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LZTR1 MUTATED	2	1	1
LZTR1 WILD-TYPE	19	13	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S138. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LZTR1 MUTATED	3	0	1
LZTR1 WILD-TYPE	27	16	7

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S139. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ERCC2 MUTATED	4	3	2	1
ERCC2 WILD-TYPE	17	17	8	8

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S140. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ERCC2 MUTATED	4	3	2	1	0
ERCC2 WILD-TYPE	9	5	12	12	7

'ERCC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0377 (Fisher's exact test), Q value = 1

Table S141. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ERCC2 MUTATED	1	7
ERCC2 WILD-TYPE	12	8

Figure S15. Get High-res Image Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'ERCC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S142. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ERCC2 MUTATED	2	3	0	1	0	1	0	1
ERCC2 WILD-TYPE	3	3	5	2	3	0	3	1

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S143. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ERCC2 MUTATED	4	2	3	1
ERCC2 WILD-TYPE	12	6	11	15

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S144. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ERCC2 MUTATED	5	4	0	1
ERCC2 WILD-TYPE	11	12	4	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S145. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	20	9	16

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.27 (Fisher's exact test), Q value = 1

Table S146. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ERCC2 MUTATED	3	2	0	5	0
ERCC2 WILD-TYPE	10	16	8	9	2

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S147. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	15	12	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S148. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ERCC2 MUTATED	8	2	0
ERCC2 WILD-TYPE	22	14	8

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S149. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RINL MUTATED	5	2	0	1
RINL WILD-TYPE	16	18	10	8

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S150. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RINL MUTATED	3	1	1	2	0
RINL WILD-TYPE	10	7	13	11	7

'RINL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S151. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RINL MUTATED	2	2
RINL WILD-TYPE	11	13

'RINL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S152. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RINL MUTATED	1	0	1	0	1	0	0	1
RINL WILD-TYPE	4	6	4	3	2	1	3	1

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S153. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	7	13	15

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S154. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	15	3	17

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S155. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RINL MUTATED	3	2	2
RINL WILD-TYPE	23	9	16

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S156. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RINL MUTATED	0	3	0	4	0
RINL WILD-TYPE	13	15	8	10	2

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S157. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RINL MUTATED	1	3	3
RINL WILD-TYPE	20	11	16

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S158. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RINL MUTATED	3	3	1
RINL WILD-TYPE	27	13	7

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S159. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SYT8 MUTATED	1	4	2	1
SYT8 WILD-TYPE	20	16	8	8

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S160. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SYT8 MUTATED	0	2	2	1	1
SYT8 WILD-TYPE	13	6	12	12	6

'SYT8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S161. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SYT8 MUTATED	1	2
SYT8 WILD-TYPE	12	13

'SYT8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S162. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SYT8 MUTATED	1	1	1	0	0	0	0	0
SYT8 WILD-TYPE	4	5	4	3	3	1	3	2

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0412 (Fisher's exact test), Q value = 1

Table S163. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SYT8 MUTATED	0	3	1	2
SYT8 WILD-TYPE	16	5	13	14

Figure S16. Get High-res Image Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S164. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SYT8 MUTATED	0	4	0	2
SYT8 WILD-TYPE	16	12	4	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S165. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SYT8 MUTATED	3	1	2
SYT8 WILD-TYPE	23	10	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S166. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SYT8 MUTATED	1	3	1	0	1
SYT8 WILD-TYPE	12	15	7	14	1

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S167. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SYT8 MUTATED	2	1	3
SYT8 WILD-TYPE	19	13	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S168. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SYT8 MUTATED	3	3	0
SYT8 WILD-TYPE	27	13	8

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S169. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LRIG1 MUTATED	5	4	3	4
LRIG1 WILD-TYPE	16	16	7	5

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S170. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LRIG1 MUTATED	3	2	2	3	1
LRIG1 WILD-TYPE	10	6	12	10	6

'LRIG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S171. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
LRIG1 MUTATED	2	2
LRIG1 WILD-TYPE	11	13

'LRIG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S172. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LRIG1 MUTATED	1	1	1	1	0	0	0	0
LRIG1 WILD-TYPE	4	5	4	2	3	1	3	2

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S173. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LRIG1 MUTATED	2	2	3	3
LRIG1 WILD-TYPE	14	6	11	13

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S174. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRIG1 MUTATED	3	2	0	5
LRIG1 WILD-TYPE	13	14	4	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S175. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LRIG1 MUTATED	4	4	3
LRIG1 WILD-TYPE	22	7	15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S176. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRIG1 MUTATED	1	3	3	4	0
LRIG1 WILD-TYPE	12	15	5	10	2

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.576 (Fisher's exact test), Q value = 1

Table S177. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LRIG1 MUTATED	3	4	4
LRIG1 WILD-TYPE	18	10	15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S178. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LRIG1 MUTATED	7	3	1
LRIG1 WILD-TYPE	23	13	7

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S179. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C1ORF106 MUTATED	4	2	2	1
C1ORF106 WILD-TYPE	17	18	8	8

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S180. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C1ORF106 MUTATED	3	0	2	1	2
C1ORF106 WILD-TYPE	10	8	12	12	5

'C1ORF106 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S181. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
C1ORF106 MUTATED	3	2
C1ORF106 WILD-TYPE	10	13

'C1ORF106 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0475 (Fisher's exact test), Q value = 1

Table S182. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C1ORF106 MUTATED	1	0	0	2	2	0	0	0
C1ORF106 WILD-TYPE	4	6	5	1	1	1	3	2

Figure S17. Get High-res Image Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S183. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C1ORF106 MUTATED	4	2	1	1
C1ORF106 WILD-TYPE	12	6	13	15

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S184. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C1ORF106 MUTATED	3	2	1	2
C1ORF106 WILD-TYPE	13	14	3	16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S185. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	21	9	17

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S186. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C1ORF106 MUTATED	1	2	2	3	0
C1ORF106 WILD-TYPE	12	16	6	11	2

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0536 (Fisher's exact test), Q value = 1

Table S187. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C1ORF106 MUTATED	5	3	0
C1ORF106 WILD-TYPE	16	11	19

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S188. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	25	14	7

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S189. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GPRIN2 MUTATED	2	3	2	1
GPRIN2 WILD-TYPE	19	17	8	8

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S190. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GPRIN2 MUTATED	1	0	4	1	1
GPRIN2 WILD-TYPE	12	8	10	12	6

'GPRIN2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S191. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
GPRIN2 MUTATED	2	2
GPRIN2 WILD-TYPE	11	13

'GPRIN2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S192. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GPRIN2 MUTATED	0	1	1	0	1	0	0	1
GPRIN2 WILD-TYPE	5	5	4	3	2	1	3	1

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S193. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GPRIN2 MUTATED	1	1	3	2
GPRIN2 WILD-TYPE	15	7	11	14

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S194. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GPRIN2 MUTATED	1	4	0	2
GPRIN2 WILD-TYPE	15	12	4	16

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S195. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GPRIN2 MUTATED	2	2	3
GPRIN2 WILD-TYPE	24	9	15

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S196. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GPRIN2 MUTATED	1	4	1	1	0
GPRIN2 WILD-TYPE	12	14	7	13	2

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S197. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GPRIN2 MUTATED	2	3	2
GPRIN2 WILD-TYPE	19	11	17

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S198. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GPRIN2 MUTATED	2	4	1
GPRIN2 WILD-TYPE	28	12	7

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S199. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CTNNB1 MUTATED	4	2	1	0
CTNNB1 WILD-TYPE	17	18	9	9

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S200. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CTNNB1 MUTATED	3	2	1	0	0
CTNNB1 WILD-TYPE	10	6	13	13	7

'CTNNB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S201. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CTNNB1 MUTATED	2	2
CTNNB1 WILD-TYPE	11	13

'CTNNB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S202. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CTNNB1 MUTATED	1	1	0	0	2	0	0	0
CTNNB1 WILD-TYPE	4	5	5	3	1	1	3	2

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0182 (Fisher's exact test), Q value = 1

Table S203. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CTNNB1 MUTATED	4	2	0	0
CTNNB1 WILD-TYPE	12	6	14	16

Figure S18. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0232 (Fisher's exact test), Q value = 1

Table S204. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CTNNB1 MUTATED	5	1	0	0
CTNNB1 WILD-TYPE	11	15	4	18

Figure S19. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00076 (Fisher's exact test), Q value = 0.45

Table S205. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CTNNB1 MUTATED	1	5	0
CTNNB1 WILD-TYPE	25	6	18

Figure S20. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S206. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CTNNB1 MUTATED	0	2	0	4	0
CTNNB1 WILD-TYPE	13	16	8	10	2

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S207. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CTNNB1 MUTATED	3	3	0
CTNNB1 WILD-TYPE	18	11	19

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.712 (Fisher's exact test), Q value = 1

Table S208. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CTNNB1 MUTATED	4	2	0
CTNNB1 WILD-TYPE	26	14	8

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S209. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C16ORF3 MUTATED	2	2	0	1
C16ORF3 WILD-TYPE	19	18	10	8

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00067 (Fisher's exact test), Q value = 0.45

Table S210. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C16ORF3 MUTATED	0	4	0	0	1
C16ORF3 WILD-TYPE	13	4	14	13	6

Figure S21. Get High-res Image Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S211. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
C16ORF3 MUTATED	1	2
C16ORF3 WILD-TYPE	12	13

'C16ORF3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S212. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C16ORF3 MUTATED	1	2	0	0	0	0	0	0
C16ORF3 WILD-TYPE	4	4	5	3	3	1	3	2

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S213. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C16ORF3 MUTATED	1	1	2	1
C16ORF3 WILD-TYPE	15	7	12	15

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S214. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C16ORF3 MUTATED	2	2	0	1
C16ORF3 WILD-TYPE	14	14	4	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S215. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C16ORF3 MUTATED	2	2	1
C16ORF3 WILD-TYPE	24	9	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S216. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C16ORF3 MUTATED	1	2	1	1	0
C16ORF3 WILD-TYPE	12	16	7	13	2

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S217. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C16ORF3 MUTATED	3	1	1
C16ORF3 WILD-TYPE	18	13	18

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S218. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C16ORF3 MUTATED	3	2	0
C16ORF3 WILD-TYPE	27	14	8

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S219. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC105 MUTATED	2	2	1	1
CCDC105 WILD-TYPE	19	18	9	8

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S220. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC105 MUTATED	1	3	0	0	2
CCDC105 WILD-TYPE	12	5	14	13	5

Figure S22. Get High-res Image Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S221. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CCDC105 MUTATED	0	3
CCDC105 WILD-TYPE	13	12

'CCDC105 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S222. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC105 MUTATED	1	1	0	0	0	0	0	1
CCDC105 WILD-TYPE	4	5	5	3	3	1	3	1

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S223. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC105 MUTATED	1	1	2	2
CCDC105 WILD-TYPE	15	7	12	14

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S224. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC105 MUTATED	3	1	0	2
CCDC105 WILD-TYPE	13	15	4	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S225. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC105 MUTATED	3	1	2
CCDC105 WILD-TYPE	23	10	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0541 (Fisher's exact test), Q value = 1

Table S226. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC105 MUTATED	1	0	2	2	1
CCDC105 WILD-TYPE	12	18	6	12	1

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S227. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC105 MUTATED	4	0	2
CCDC105 WILD-TYPE	17	14	17

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S228. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC105 MUTATED	5	0	1
CCDC105 WILD-TYPE	25	16	7

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S229. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RGS9BP MUTATED	3	3	2	0
RGS9BP WILD-TYPE	18	17	8	9

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S230. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RGS9BP MUTATED	3	0	3	1	1
RGS9BP WILD-TYPE	10	8	11	12	6

'RGS9BP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RGS9BP MUTATED	1	2
RGS9BP WILD-TYPE	12	13

'RGS9BP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S232. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RGS9BP MUTATED	0	2	0	0	0	1	0	0
RGS9BP WILD-TYPE	5	4	5	3	3	0	3	2

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S233. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RGS9BP MUTATED	2	1	2	2
RGS9BP WILD-TYPE	14	7	12	14

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S234. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RGS9BP MUTATED	2	3	0	2
RGS9BP WILD-TYPE	14	13	4	16

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S235. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RGS9BP MUTATED	2	3	3
RGS9BP WILD-TYPE	24	8	15

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S236. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RGS9BP MUTATED	2	2	1	3	0
RGS9BP WILD-TYPE	11	16	7	11	2

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S237. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RGS9BP MUTATED	2	4	2
RGS9BP WILD-TYPE	19	10	17

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S238. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RGS9BP MUTATED	4	2	2
RGS9BP WILD-TYPE	26	14	6

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S239. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HHIPL1 MUTATED	3	1	0	2
HHIPL1 WILD-TYPE	18	19	10	7

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S240. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HHIPL1 MUTATED	2	0	0	2	1
HHIPL1 WILD-TYPE	11	8	14	11	6

'HHIPL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S241. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
HHIPL1 MUTATED	0	2
HHIPL1 WILD-TYPE	13	13

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S242. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HHIPL1 MUTATED	3	0	1	1
HHIPL1 WILD-TYPE	13	8	13	15

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S243. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HHIPL1 MUTATED	2	1	1	1
HHIPL1 WILD-TYPE	14	15	3	17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S244. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HHIPL1 MUTATED	4	1	0
HHIPL1 WILD-TYPE	22	10	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S245. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HHIPL1 MUTATED	2	0	1	2	0
HHIPL1 WILD-TYPE	11	18	7	12	2

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S246. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HHIPL1 MUTATED	4	0	1
HHIPL1 WILD-TYPE	17	14	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S247. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HHIPL1 MUTATED	4	0	1
HHIPL1 WILD-TYPE	26	16	7

'C10ORF95 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S248. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C10ORF95 MUTATED	2	0	2	1
C10ORF95 WILD-TYPE	19	20	8	8

'C10ORF95 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S249. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C10ORF95 MUTATED	1	0	3	0	1
C10ORF95 WILD-TYPE	12	8	11	13	6

'C10ORF95 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S250. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
C10ORF95 MUTATED	1	1
C10ORF95 WILD-TYPE	12	14

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S251. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C10ORF95 MUTATED	1	2	1	1
C10ORF95 WILD-TYPE	15	6	13	15

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S252. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C10ORF95 MUTATED	1	2	0	2
C10ORF95 WILD-TYPE	15	14	4	16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S253. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C10ORF95 MUTATED	4	0	1
C10ORF95 WILD-TYPE	22	11	17

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S254. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C10ORF95 MUTATED	1	1	1	1	1
C10ORF95 WILD-TYPE	12	17	7	13	1

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S255. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C10ORF95 MUTATED	2	1	1
C10ORF95 WILD-TYPE	19	13	18

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S256. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C10ORF95 MUTATED	3	1	0
C10ORF95 WILD-TYPE	27	15	8

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.947 (Fisher's exact test), Q value = 1

Table S257. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TSC22D2 MUTATED	4	2	1	1
TSC22D2 WILD-TYPE	17	18	9	8

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S258. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TSC22D2 MUTATED	2	0	2	1	2
TSC22D2 WILD-TYPE	11	8	12	12	5

'TSC22D2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S259. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TSC22D2 MUTATED	1	2
TSC22D2 WILD-TYPE	12	13

'TSC22D2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S260. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TSC22D2 MUTATED	0	1	1	0	1	0	0	0
TSC22D2 WILD-TYPE	5	5	4	3	2	1	3	2

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S261. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TSC22D2 MUTATED	3	0	2	2
TSC22D2 WILD-TYPE	13	8	12	14

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S262. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TSC22D2 MUTATED	2	2	1	2
TSC22D2 WILD-TYPE	14	14	3	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S263. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TSC22D2 MUTATED	3	2	2
TSC22D2 WILD-TYPE	23	9	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S264. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TSC22D2 MUTATED	1	2	0	4	0
TSC22D2 WILD-TYPE	12	16	8	10	2

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S265. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TSC22D2 MUTATED	1	3	3
TSC22D2 WILD-TYPE	20	11	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S266. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TSC22D2 MUTATED	4	2	1
TSC22D2 WILD-TYPE	26	14	7

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S267. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOXA1 MUTATED	3	0	2	0
NOXA1 WILD-TYPE	18	20	8	9

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S268. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOXA1 MUTATED	2	0	1	0	0
NOXA1 WILD-TYPE	11	8	13	13	7

'NOXA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S269. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NOXA1 MUTATED	1	1
NOXA1 WILD-TYPE	12	14

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S270. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	7	14	16

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S271. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	15	4	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S272. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	23	11	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S273. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOXA1 MUTATED	1	0	0	2	0
NOXA1 WILD-TYPE	12	18	8	12	2

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S274. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOXA1 MUTATED	1	2	0
NOXA1 WILD-TYPE	20	12	19

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S275. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	27	16	8

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S276. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
THEM4 MUTATED	3	0	1	1
THEM4 WILD-TYPE	18	20	9	8

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S277. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
THEM4 MUTATED	1	1	1	0	1
THEM4 WILD-TYPE	12	7	13	13	6

'THEM4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S278. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
THEM4 MUTATED	0	1
THEM4 WILD-TYPE	13	14

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S279. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
THEM4 MUTATED	1	1	2	0
THEM4 WILD-TYPE	15	7	12	16

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S280. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
THEM4 MUTATED	2	1	0	1
THEM4 WILD-TYPE	14	15	4	17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S281. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
THEM4 MUTATED	2	2	0
THEM4 WILD-TYPE	24	9	18

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S282. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
THEM4 MUTATED	0	0	1	3	0
THEM4 WILD-TYPE	13	18	7	11	2

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S283. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
THEM4 MUTATED	3	1	0
THEM4 WILD-TYPE	18	13	19

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 1

Table S284. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
THEM4 MUTATED	4	0	0
THEM4 WILD-TYPE	26	16	8

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S285. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ATXN1 MUTATED	2	4	3	1
ATXN1 WILD-TYPE	19	16	7	8

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S286. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ATXN1 MUTATED	1	4	2	1	1
ATXN1 WILD-TYPE	12	4	12	12	6

'ATXN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S287. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ATXN1 MUTATED	1	3
ATXN1 WILD-TYPE	12	12

'ATXN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S288. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ATXN1 MUTATED	2	1	1	0	0	0	0	0
ATXN1 WILD-TYPE	3	5	4	3	3	1	3	2

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S289. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ATXN1 MUTATED	2	3	3	1
ATXN1 WILD-TYPE	14	5	11	15

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S290. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ATXN1 MUTATED	3	4	0	2
ATXN1 WILD-TYPE	13	12	4	16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 1

Table S291. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ATXN1 MUTATED	5	3	1
ATXN1 WILD-TYPE	21	8	17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S292. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ATXN1 MUTATED	2	2	2	3	0
ATXN1 WILD-TYPE	11	16	6	11	2

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S293. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ATXN1 MUTATED	6	1	2
ATXN1 WILD-TYPE	15	13	17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S294. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ATXN1 MUTATED	7	2	0
ATXN1 WILD-TYPE	23	14	8

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.501 (Fisher's exact test), Q value = 1

Table S295. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	20	17	10	8

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S296. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PLIN5 MUTATED	1	2	1	1	0
PLIN5 WILD-TYPE	12	6	13	12	7

'PLIN5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S297. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PLIN5 MUTATED	1	2
PLIN5 WILD-TYPE	12	13

'PLIN5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S298. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLIN5 MUTATED	0	1	0	0	1	0	0	1
PLIN5 WILD-TYPE	5	5	5	3	2	1	3	1

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S299. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PLIN5 MUTATED	1	1	2	1
PLIN5 WILD-TYPE	15	7	12	15

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S300. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	15	13	4	17

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S301. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PLIN5 MUTATED	1	2	2
PLIN5 WILD-TYPE	25	9	16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S302. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLIN5 MUTATED	1	4	0	0	0
PLIN5 WILD-TYPE	12	14	8	14	2

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S303. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PLIN5 MUTATED	1	1	3
PLIN5 WILD-TYPE	20	13	16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.048 (Fisher's exact test), Q value = 1

Table S304. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PLIN5 MUTATED	1	4	0
PLIN5 WILD-TYPE	29	12	8

Figure S23. Get High-res Image Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S305. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
OPRD1 MUTATED	5	4	2	1
OPRD1 WILD-TYPE	16	16	8	8

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S306. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
OPRD1 MUTATED	3	1	3	1	3
OPRD1 WILD-TYPE	10	7	11	12	4

'OPRD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S307. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
OPRD1 MUTATED	2	4
OPRD1 WILD-TYPE	11	11

'OPRD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S308. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OPRD1 MUTATED	0	2	1	1	2	0	0	0
OPRD1 WILD-TYPE	5	4	4	2	1	1	3	2

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S309. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
OPRD1 MUTATED	4	2	3	2
OPRD1 WILD-TYPE	12	6	11	14

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S310. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OPRD1 MUTATED	3	4	1	3
OPRD1 WILD-TYPE	13	12	3	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S311. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
OPRD1 MUTATED	5	4	2
OPRD1 WILD-TYPE	21	7	16

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S312. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OPRD1 MUTATED	1	5	1	4	0
OPRD1 WILD-TYPE	12	13	7	10	2

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S313. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
OPRD1 MUTATED	4	3	4
OPRD1 WILD-TYPE	17	11	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S314. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
OPRD1 MUTATED	5	5	1
OPRD1 WILD-TYPE	25	11	7

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S315. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KRTAP4-5 MUTATED	2	3	0	0
KRTAP4-5 WILD-TYPE	19	17	10	9

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S316. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KRTAP4-5 MUTATED	1	2	0	1	0
KRTAP4-5 WILD-TYPE	12	6	14	12	7

'KRTAP4-5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S317. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KRTAP4-5 MUTATED	0	2
KRTAP4-5 WILD-TYPE	13	13

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S318. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KRTAP4-5 MUTATED	2	0	1	1
KRTAP4-5 WILD-TYPE	14	8	13	15

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S319. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KRTAP4-5 MUTATED	2	1	0	1
KRTAP4-5 WILD-TYPE	14	15	4	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S320. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KRTAP4-5 MUTATED	2	1	1
KRTAP4-5 WILD-TYPE	24	10	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S321. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KRTAP4-5 MUTATED	1	1	0	2	0
KRTAP4-5 WILD-TYPE	12	17	8	12	2

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S322. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KRTAP4-5 MUTATED	3	0	1
KRTAP4-5 WILD-TYPE	18	14	18

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S323. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KRTAP4-5 MUTATED	3	1	0
KRTAP4-5 WILD-TYPE	27	15	8

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S324. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C19ORF10 MUTATED	3	2	0	1
C19ORF10 WILD-TYPE	18	18	10	8

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 1

Table S325. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C19ORF10 MUTATED	2	1	3	0	0
C19ORF10 WILD-TYPE	11	7	11	13	7

'C19ORF10 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S326. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
C19ORF10 MUTATED	1	3
C19ORF10 WILD-TYPE	12	12

'C19ORF10 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S327. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C19ORF10 MUTATED	0	2	0	0	1	0	0	1
C19ORF10 WILD-TYPE	5	4	5	3	2	1	3	1

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S328. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C19ORF10 MUTATED	2	2	2	0
C19ORF10 WILD-TYPE	14	6	12	16

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S329. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C19ORF10 MUTATED	2	4	0	0
C19ORF10 WILD-TYPE	14	12	4	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S330. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C19ORF10 MUTATED	3	2	1
C19ORF10 WILD-TYPE	23	9	17

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S331. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C19ORF10 MUTATED	2	2	0	2	0
C19ORF10 WILD-TYPE	11	16	8	12	2

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S332. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C19ORF10 MUTATED	3	2	1
C19ORF10 WILD-TYPE	18	12	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.712 (Fisher's exact test), Q value = 1

Table S333. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C19ORF10 MUTATED	4	2	0
C19ORF10 WILD-TYPE	26	14	8

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S334. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AATK MUTATED	0	4	1	1
AATK WILD-TYPE	21	16	9	8

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S335. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AATK MUTATED	0	1	2	0	1
AATK WILD-TYPE	13	7	12	13	6

'AATK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S336. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
AATK MUTATED	1	1
AATK WILD-TYPE	12	14

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S337. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AATK MUTATED	0	1	2	1
AATK WILD-TYPE	16	7	12	15

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S338. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AATK MUTATED	0	3	0	1
AATK WILD-TYPE	16	13	4	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S339. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AATK MUTATED	2	1	1
AATK WILD-TYPE	24	10	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S340. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AATK MUTATED	2	2	0	0	0
AATK WILD-TYPE	11	16	8	14	2

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S341. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AATK MUTATED	2	1	1
AATK WILD-TYPE	19	13	18

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S342. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AATK MUTATED	2	2	0
AATK WILD-TYPE	28	14	8

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S343. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SARM1 MUTATED	3	0	2	1
SARM1 WILD-TYPE	18	20	8	8

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S344. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SARM1 MUTATED	0	1	3	1	0
SARM1 WILD-TYPE	13	7	11	12	7

'SARM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S345. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SARM1 MUTATED	1	3
SARM1 WILD-TYPE	12	12

'SARM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S346. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SARM1 MUTATED	1	1	0	0	1	0	0	1
SARM1 WILD-TYPE	4	5	5	3	2	1	3	1

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S347. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SARM1 MUTATED	1	1	3	0
SARM1 WILD-TYPE	15	7	11	16

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S348. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SARM1 MUTATED	1	3	1	0
SARM1 WILD-TYPE	15	13	3	18

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S349. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SARM1 MUTATED	1	2	2
SARM1 WILD-TYPE	25	9	16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S350. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SARM1 MUTATED	2	2	0	1	0
SARM1 WILD-TYPE	11	16	8	13	2

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S351. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SARM1 MUTATED	1	1	3
SARM1 WILD-TYPE	20	13	16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.08 (Fisher's exact test), Q value = 1

Table S352. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SARM1 MUTATED	1	2	2
SARM1 WILD-TYPE	29	14	6

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S353. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TRIOBP MUTATED	4	4	2	0
TRIOBP WILD-TYPE	17	16	8	9

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S354. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TRIOBP MUTATED	3	1	0	3	2
TRIOBP WILD-TYPE	10	7	14	10	5

'TRIOBP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S355. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TRIOBP MUTATED	2	1
TRIOBP WILD-TYPE	11	14

'TRIOBP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S356. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TRIOBP MUTATED	1	0	0	0	0	0	2	0
TRIOBP WILD-TYPE	4	6	5	3	3	1	1	2

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S357. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TRIOBP MUTATED	2	1	2	3
TRIOBP WILD-TYPE	14	7	12	13

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S358. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TRIOBP MUTATED	3	0	0	5
TRIOBP WILD-TYPE	13	16	4	13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S359. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TRIOBP MUTATED	4	1	4
TRIOBP WILD-TYPE	22	10	14

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S360. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TRIOBP MUTATED	2	2	2	3	0
TRIOBP WILD-TYPE	11	16	6	11	2

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S361. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TRIOBP MUTATED	4	2	3
TRIOBP WILD-TYPE	17	12	16

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S362. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TRIOBP MUTATED	5	2	2
TRIOBP WILD-TYPE	25	14	6

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S363. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF598 MUTATED	8	2	1	1
ZNF598 WILD-TYPE	13	18	9	8

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S364. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF598 MUTATED	3	0	2	4	0
ZNF598 WILD-TYPE	10	8	12	9	7

'ZNF598 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S365. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZNF598 MUTATED	3	3
ZNF598 WILD-TYPE	10	12

'ZNF598 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S366. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF598 MUTATED	1	0	2	1	1	0	1	0
ZNF598 WILD-TYPE	4	6	3	2	2	1	2	2

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S367. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF598 MUTATED	4	0	3	2
ZNF598 WILD-TYPE	12	8	11	14

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.951 (Fisher's exact test), Q value = 1

Table S368. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF598 MUTATED	3	2	1	3
ZNF598 WILD-TYPE	13	14	3	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S369. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF598 MUTATED	4	2	3
ZNF598 WILD-TYPE	22	9	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S370. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF598 MUTATED	1	3	0	5	0
ZNF598 WILD-TYPE	12	15	8	9	2

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S371. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF598 MUTATED	3	2	4
ZNF598 WILD-TYPE	18	12	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S372. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF598 MUTATED	5	3	1
ZNF598 WILD-TYPE	25	13	7

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S373. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
WDR34 MUTATED	3	1	0	1
WDR34 WILD-TYPE	18	19	10	8

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S374. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
WDR34 MUTATED	2	0	1	1	1
WDR34 WILD-TYPE	11	8	13	12	6

'WDR34 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S375. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
WDR34 MUTATED	0	2
WDR34 WILD-TYPE	13	13

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S376. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
WDR34 MUTATED	2	0	1	2
WDR34 WILD-TYPE	14	8	13	14

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S377. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
WDR34 MUTATED	2	2	0	1
WDR34 WILD-TYPE	14	14	4	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S378. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
WDR34 MUTATED	3	1	1
WDR34 WILD-TYPE	23	10	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S379. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
WDR34 MUTATED	1	1	0	3	0
WDR34 WILD-TYPE	12	17	8	11	2

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S380. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
WDR34 MUTATED	2	2	1
WDR34 WILD-TYPE	19	12	18

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S381. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
WDR34 MUTATED	4	0	1
WDR34 WILD-TYPE	26	16	7

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S382. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF628 MUTATED	5	1	0	1
ZNF628 WILD-TYPE	16	19	10	8

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S383. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF628 MUTATED	2	1	1	1	0
ZNF628 WILD-TYPE	11	7	13	12	7

'ZNF628 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S384. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZNF628 MUTATED	1	2
ZNF628 WILD-TYPE	12	13

'ZNF628 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S385. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF628 MUTATED	1	1	0	0	0	0	0	1
ZNF628 WILD-TYPE	4	5	5	3	3	1	3	1

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S386. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	7	13	16

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S387. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	15	3	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.093 (Fisher's exact test), Q value = 1

Table S388. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	25	8	17

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.5 (Fisher's exact test), Q value = 1

Table S389. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF628 MUTATED	0	3	0	2	0
ZNF628 WILD-TYPE	13	15	8	12	2

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 1

Table S390. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	20	11	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S391. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF628 MUTATED	2	2	1
ZNF628 WILD-TYPE	28	14	7

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S392. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
BTBD11 MUTATED	2	2	1	1
BTBD11 WILD-TYPE	19	18	9	8

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S393. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
BTBD11 MUTATED	1	1	1	0	2
BTBD11 WILD-TYPE	12	7	13	13	5

'BTBD11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S394. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
BTBD11 MUTATED	0	1
BTBD11 WILD-TYPE	13	14

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S395. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
BTBD11 MUTATED	1	0	3	1
BTBD11 WILD-TYPE	15	8	11	15

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S396. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BTBD11 MUTATED	1	2	0	2
BTBD11 WILD-TYPE	15	14	4	16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S397. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	22	11	17

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S398. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BTBD11 MUTATED	2	0	2	1	0
BTBD11 WILD-TYPE	11	18	6	13	2

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S399. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
BTBD11 MUTATED	3	1	1
BTBD11 WILD-TYPE	18	13	18

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S400. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	26	16	7

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S401. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IRX3 MUTATED	3	0	2	0
IRX3 WILD-TYPE	18	20	8	9

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S402. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
IRX3 MUTATED	0	1	2	1	0
IRX3 WILD-TYPE	13	7	12	12	7

'IRX3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S403. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
IRX3 MUTATED	0	2
IRX3 WILD-TYPE	13	13

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S404. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
IRX3 MUTATED	2	1	1	0
IRX3 WILD-TYPE	14	7	13	16

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S405. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IRX3 MUTATED	1	2	1	0
IRX3 WILD-TYPE	15	14	3	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S406. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
IRX3 MUTATED	2	2	0
IRX3 WILD-TYPE	24	9	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S407. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IRX3 MUTATED	2	1	0	1	0
IRX3 WILD-TYPE	11	17	8	13	2

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S408. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
IRX3 MUTATED	3	1	0
IRX3 WILD-TYPE	18	13	19

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S409. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
IRX3 MUTATED	3	0	1
IRX3 WILD-TYPE	27	16	7

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S410. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FPGS MUTATED	2	2	1	0
FPGS WILD-TYPE	19	18	9	9

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S411. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FPGS MUTATED	1	1	1	1	0
FPGS WILD-TYPE	12	7	13	12	7

'FPGS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S412. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
FPGS MUTATED	1	2
FPGS WILD-TYPE	12	13

'FPGS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S413. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
FPGS MUTATED	1	1	0	0	0	1	0	0
FPGS WILD-TYPE	4	5	5	3	3	0	3	2

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S414. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FPGS MUTATED	1	1	0	2
FPGS WILD-TYPE	15	7	14	14

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S415. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FPGS MUTATED	2	0	0	2
FPGS WILD-TYPE	14	16	4	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0568 (Fisher's exact test), Q value = 1

Table S416. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FPGS MUTATED	0	2	2
FPGS WILD-TYPE	26	9	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S417. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FPGS MUTATED	0	2	0	2	0
FPGS WILD-TYPE	13	16	8	12	2

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S418. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FPGS MUTATED	1	1	2
FPGS WILD-TYPE	20	13	17

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S419. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FPGS MUTATED	2	2	0
FPGS WILD-TYPE	28	14	8

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S420. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MEN1 MUTATED	1	1	2	0
MEN1 WILD-TYPE	20	19	8	9

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0472 (Fisher's exact test), Q value = 1

Table S421. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MEN1 MUTATED	0	1	4	0	0
MEN1 WILD-TYPE	13	7	10	13	7

Figure S24. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S422. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MEN1 MUTATED	0	2
MEN1 WILD-TYPE	13	13

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0128 (Fisher's exact test), Q value = 1

Table S423. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MEN1 MUTATED	0	1	4	0
MEN1 WILD-TYPE	16	7	10	16

Figure S25. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00638 (Fisher's exact test), Q value = 1

Table S424. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MEN1 MUTATED	0	5	0	0
MEN1 WILD-TYPE	16	11	4	18

Figure S26. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S425. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	22	10	18

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0426 (Fisher's exact test), Q value = 1

Table S426. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MEN1 MUTATED	4	0	0	1	0
MEN1 WILD-TYPE	9	18	8	13	2

Figure S27. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S427. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	17	13	19

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S428. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MEN1 MUTATED	5	0	0
MEN1 WILD-TYPE	25	16	8

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S429. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
BHLHE22 MUTATED	1	2	2	0
BHLHE22 WILD-TYPE	20	18	8	9

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0735 (Fisher's exact test), Q value = 1

Table S430. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
BHLHE22 MUTATED	0	3	1	1	0
BHLHE22 WILD-TYPE	13	5	13	12	7

'BHLHE22 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S431. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
BHLHE22 MUTATED	2	2
BHLHE22 WILD-TYPE	11	13

'BHLHE22 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S432. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
BHLHE22 MUTATED	2	1	1	0	0	0	0	0
BHLHE22 WILD-TYPE	3	5	4	3	3	1	3	2

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S433. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
BHLHE22 MUTATED	0	2	2	1
BHLHE22 WILD-TYPE	16	6	12	15

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S434. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BHLHE22 MUTATED	2	2	0	1
BHLHE22 WILD-TYPE	14	14	4	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S435. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
BHLHE22 MUTATED	2	2	1
BHLHE22 WILD-TYPE	24	9	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S436. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BHLHE22 MUTATED	2	2	0	1	0
BHLHE22 WILD-TYPE	11	16	8	13	2

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S437. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
BHLHE22 MUTATED	3	1	1
BHLHE22 WILD-TYPE	18	13	18

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S438. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
BHLHE22 MUTATED	3	2	0
BHLHE22 WILD-TYPE	27	14	8

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S439. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DMKN MUTATED	2	1	0	0
DMKN WILD-TYPE	19	19	10	9

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S440. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
DMKN MUTATED	0	1	2	0	0
DMKN WILD-TYPE	13	7	12	13	7

'DMKN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S441. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
DMKN MUTATED	1	0
DMKN WILD-TYPE	12	15

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.619 (Fisher's exact test), Q value = 1

Table S442. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	15	7	13	16

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S443. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DMKN MUTATED	1	2	0	0
DMKN WILD-TYPE	15	14	4	18

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00644 (Fisher's exact test), Q value = 1

Table S444. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	26	8	18

Figure S28. Get High-res Image Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S445. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DMKN MUTATED	0	1	0	2	0
DMKN WILD-TYPE	13	17	8	12	2

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.255 (Fisher's exact test), Q value = 1

Table S446. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
DMKN MUTATED	1	2	0
DMKN WILD-TYPE	20	12	19

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S447. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
DMKN MUTATED	2	1	0
DMKN WILD-TYPE	28	15	8

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 1

Table S448. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
OBSCN MUTATED	9	6	1	2
OBSCN WILD-TYPE	12	14	9	7

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S449. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
OBSCN MUTATED	4	4	2	4	2
OBSCN WILD-TYPE	9	4	12	9	5

'OBSCN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S450. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
OBSCN MUTATED	4	4
OBSCN WILD-TYPE	9	11

'OBSCN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S451. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OBSCN MUTATED	1	2	1	0	2	0	2	0
OBSCN WILD-TYPE	4	4	4	3	1	1	1	2

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S452. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
OBSCN MUTATED	6	2	5	3
OBSCN WILD-TYPE	10	6	9	13

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S453. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OBSCN MUTATED	5	4	2	5
OBSCN WILD-TYPE	11	12	2	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 1

Table S454. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
OBSCN MUTATED	6	6	4
OBSCN WILD-TYPE	20	5	14

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S455. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OBSCN MUTATED	2	5	3	6	0
OBSCN WILD-TYPE	11	13	5	8	2

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
OBSCN MUTATED	6	4	6
OBSCN WILD-TYPE	15	10	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S457. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
OBSCN MUTATED	8	4	4
OBSCN WILD-TYPE	22	12	4

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S458. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PANK2 MUTATED	3	1	0	1
PANK2 WILD-TYPE	18	19	10	8

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S459. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PANK2 MUTATED	2	0	0	1	0
PANK2 WILD-TYPE	11	8	14	12	7

'PANK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S460. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PANK2 MUTATED	0	3
PANK2 WILD-TYPE	13	12

'PANK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S461. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PANK2 MUTATED	2	0	0	0	1	0	0	0
PANK2 WILD-TYPE	3	6	5	3	2	1	3	2

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S462. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PANK2 MUTATED	3	0	0	0
PANK2 WILD-TYPE	13	8	14	16

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0513 (Fisher's exact test), Q value = 1

Table S463. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PANK2 MUTATED	2	0	1	0
PANK2 WILD-TYPE	14	16	3	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S464. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PANK2 MUTATED	2	1	0
PANK2 WILD-TYPE	24	10	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S465. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PANK2 MUTATED	1	0	0	2	0
PANK2 WILD-TYPE	12	18	8	12	2

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S466. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PANK2 MUTATED	1	1	1
PANK2 WILD-TYPE	20	13	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S467. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PANK2 MUTATED	2	0	1
PANK2 WILD-TYPE	28	16	7

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S468. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RREB1 MUTATED	3	1	1	0
RREB1 WILD-TYPE	18	19	9	9

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S469. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RREB1 MUTATED	2	0	1	1	0
RREB1 WILD-TYPE	11	8	13	12	7

'RREB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S470. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RREB1 MUTATED	2	0
RREB1 WILD-TYPE	11	15

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S471. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RREB1 MUTATED	1	1	1	0
RREB1 WILD-TYPE	15	7	13	16

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S472. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RREB1 MUTATED	1	1	0	1
RREB1 WILD-TYPE	15	15	4	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S473. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RREB1 MUTATED	1	1	2
RREB1 WILD-TYPE	25	10	16

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S474. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RREB1 MUTATED	2	2	0	0	0
RREB1 WILD-TYPE	11	16	8	14	2

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S475. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RREB1 MUTATED	0	2	2
RREB1 WILD-TYPE	21	12	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S476. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RREB1 MUTATED	1	2	1
RREB1 WILD-TYPE	29	14	7

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S477. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF149 MUTATED	0	2	1	1
RNF149 WILD-TYPE	21	18	9	8

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0364 (Fisher's exact test), Q value = 1

Table S478. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RNF149 MUTATED	0	0	2	0	2
RNF149 WILD-TYPE	13	8	12	13	5

Figure S29. Get High-res Image Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RNF149 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S479. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RNF149 MUTATED	2	1
RNF149 WILD-TYPE	11	14

'RNF149 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.955 (Fisher's exact test), Q value = 1

Table S480. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF149 MUTATED	0	1	1	0	1	0	0	0
RNF149 WILD-TYPE	5	5	4	3	2	1	3	2

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S481. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RNF149 MUTATED	0	1	2	1
RNF149 WILD-TYPE	16	7	12	15

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S482. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF149 MUTATED	0	2	0	2
RNF149 WILD-TYPE	16	14	4	16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S483. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	25	9	17

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S484. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF149 MUTATED	0	3	1	0	0
RNF149 WILD-TYPE	13	15	7	14	2

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S485. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	20	12	18

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S486. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RNF149 MUTATED	1	3	0
RNF149 WILD-TYPE	29	13	8

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S487. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GLTPD2 MUTATED	3	1	1	1
GLTPD2 WILD-TYPE	18	19	9	8

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S488. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GLTPD2 MUTATED	1	0	2	2	1
GLTPD2 WILD-TYPE	12	8	12	11	6

'GLTPD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S489. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
GLTPD2 MUTATED	0	2
GLTPD2 WILD-TYPE	13	13

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S490. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GLTPD2 MUTATED	2	0	2	2
GLTPD2 WILD-TYPE	14	8	12	14

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S491. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GLTPD2 MUTATED	1	3	1	1
GLTPD2 WILD-TYPE	15	13	3	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S492. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GLTPD2 MUTATED	3	2	1
GLTPD2 WILD-TYPE	23	9	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S493. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GLTPD2 MUTATED	2	1	0	3	0
GLTPD2 WILD-TYPE	11	17	8	11	2

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S494. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GLTPD2 MUTATED	3	1	2
GLTPD2 WILD-TYPE	18	13	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S495. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GLTPD2 MUTATED	4	0	2
GLTPD2 WILD-TYPE	26	16	6

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S496. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	18	19	10	8

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S497. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SNED1 MUTATED	2	2	1	0	0
SNED1 WILD-TYPE	11	6	13	13	7

'SNED1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S498. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SNED1 MUTATED	1	0
SNED1 WILD-TYPE	12	15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S499. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	7	14	15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S500. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	15	4	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0941 (Fisher's exact test), Q value = 1

Table S501. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SNED1 MUTATED	1	3	1
SNED1 WILD-TYPE	25	8	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S502. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SNED1 MUTATED	0	2	1	2	0
SNED1 WILD-TYPE	13	16	7	12	2

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S503. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SNED1 MUTATED	2	1	2
SNED1 WILD-TYPE	19	13	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S504. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SNED1 MUTATED	2	2	1
SNED1 WILD-TYPE	28	14	7

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S505. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TPO MUTATED	7	2	1	2
TPO WILD-TYPE	14	18	9	7

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S506. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TPO MUTATED	3	3	1	2	0
TPO WILD-TYPE	10	5	13	11	7

'TPO MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S507. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TPO MUTATED	0	4
TPO WILD-TYPE	13	11

'TPO MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S508. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TPO MUTATED	2	1	0	0	1	0	0	0
TPO WILD-TYPE	3	5	5	3	2	1	3	2

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S509. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TPO MUTATED	5	2	1	1
TPO WILD-TYPE	11	6	13	15

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S510. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TPO MUTATED	4	2	2	1
TPO WILD-TYPE	12	14	2	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0981 (Fisher's exact test), Q value = 1

Table S511. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TPO MUTATED	4	4	1
TPO WILD-TYPE	22	7	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S512. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TPO MUTATED	1	2	1	5	0
TPO WILD-TYPE	12	16	7	9	2

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S513. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TPO MUTATED	4	2	3
TPO WILD-TYPE	17	12	16

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S514. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TPO MUTATED	5	1	3
TPO WILD-TYPE	25	15	5

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S515. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PTPLA MUTATED	2	0	1	1
PTPLA WILD-TYPE	19	20	9	8

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S516. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PTPLA MUTATED	0	1	2	0	0
PTPLA WILD-TYPE	13	7	12	13	7

'PTPLA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S517. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PTPLA MUTATED	0	1
PTPLA WILD-TYPE	13	14

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S518. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PTPLA MUTATED	1	0	2	0
PTPLA WILD-TYPE	15	8	12	16

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S519. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PTPLA MUTATED	1	2	0	0
PTPLA WILD-TYPE	15	14	4	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S520. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PTPLA MUTATED	1	1	1
PTPLA WILD-TYPE	25	10	17

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S521. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PTPLA MUTATED	1	1	0	1	0
PTPLA WILD-TYPE	12	17	8	13	2

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S522. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PTPLA MUTATED	2	0	1
PTPLA WILD-TYPE	19	14	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S523. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PTPLA MUTATED	2	1	0
PTPLA WILD-TYPE	28	15	8

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S524. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	20	19	9	9

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S525. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PRSS27 MUTATED	0	1	1	1	0
PRSS27 WILD-TYPE	13	7	13	12	7

'PRSS27 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S526. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PRSS27 MUTATED	0	1
PRSS27 WILD-TYPE	13	14

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S527. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	15	7	13	16

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0502 (Fisher's exact test), Q value = 1

Table S528. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRSS27 MUTATED	0	2	1	0
PRSS27 WILD-TYPE	16	14	3	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S529. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PRSS27 MUTATED	1	2	0
PRSS27 WILD-TYPE	25	9	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S530. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRSS27 MUTATED	1	1	0	1	0
PRSS27 WILD-TYPE	12	17	8	13	2

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S531. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PRSS27 MUTATED	1	0	2
PRSS27 WILD-TYPE	20	14	17

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S532. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PRSS27 MUTATED	1	1	1
PRSS27 WILD-TYPE	29	15	7

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S533. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CD320 MUTATED	2	1	1	0
CD320 WILD-TYPE	19	19	9	9

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S534. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CD320 MUTATED	1	0	1	2	0
CD320 WILD-TYPE	12	8	13	11	7

'CD320 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S535. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CD320 MUTATED	1	1
CD320 WILD-TYPE	12	14

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S536. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CD320 MUTATED	1	0	2	1
CD320 WILD-TYPE	15	8	12	15

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S537. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CD320 MUTATED	1	1	1	1
CD320 WILD-TYPE	15	15	3	17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S538. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	23	10	18

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S539. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CD320 MUTATED	1	0	2	1	0
CD320 WILD-TYPE	12	18	6	13	2

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S540. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	18	13	19

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 1

Table S541. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CD320 MUTATED	4	0	0
CD320 WILD-TYPE	26	16	8

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S542. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SEMA5B MUTATED	5	2	0	1
SEMA5B WILD-TYPE	16	18	10	8

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S543. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SEMA5B MUTATED	2	1	0	3	0
SEMA5B WILD-TYPE	11	7	14	10	7

'SEMA5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S544. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SEMA5B MUTATED	3	1
SEMA5B WILD-TYPE	10	14

'SEMA5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S545. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEMA5B MUTATED	2	0	1	0	0	1	0	0
SEMA5B WILD-TYPE	3	6	4	3	3	0	3	2

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S546. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SEMA5B MUTATED	3	1	0	2
SEMA5B WILD-TYPE	13	7	14	14

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S547. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEMA5B MUTATED	3	0	1	2
SEMA5B WILD-TYPE	13	16	3	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S548. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SEMA5B MUTATED	2	2	2
SEMA5B WILD-TYPE	24	9	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.297 (Fisher's exact test), Q value = 1

Table S549. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEMA5B MUTATED	0	4	0	2	0
SEMA5B WILD-TYPE	13	14	8	12	2

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S550. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SEMA5B MUTATED	1	3	2
SEMA5B WILD-TYPE	20	11	17

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S551. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SEMA5B MUTATED	2	3	1
SEMA5B WILD-TYPE	28	13	7

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S552. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC150 MUTATED	2	0	2	0
CCDC150 WILD-TYPE	19	20	8	9

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S553. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC150 MUTATED	2	0	1	1	0
CCDC150 WILD-TYPE	11	8	13	12	7

'CCDC150 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S554. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CCDC150 MUTATED	0	3
CCDC150 WILD-TYPE	13	12

'CCDC150 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S555. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC150 MUTATED	0	1	0	1	1	0	0	0
CCDC150 WILD-TYPE	5	5	5	2	2	1	3	2

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S556. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC150 MUTATED	3	0	1	0
CCDC150 WILD-TYPE	13	8	13	16

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S557. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC150 MUTATED	2	1	1	0
CCDC150 WILD-TYPE	14	15	3	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S558. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC150 MUTATED	3	1	0
CCDC150 WILD-TYPE	23	10	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S559. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC150 MUTATED	1	0	0	3	0
CCDC150 WILD-TYPE	12	18	8	11	2

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S560. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC150 MUTATED	2	1	1
CCDC150 WILD-TYPE	19	13	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S561. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC150 MUTATED	3	0	1
CCDC150 WILD-TYPE	27	16	7

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S562. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TAF5 MUTATED	2	1	1	0
TAF5 WILD-TYPE	19	19	9	9

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S563. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TAF5 MUTATED	1	1	1	0	1
TAF5 WILD-TYPE	12	7	13	13	6

'TAF5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S564. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TAF5 MUTATED	2	1
TAF5 WILD-TYPE	11	14

'TAF5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S565. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TAF5 MUTATED	1	1	0	0	1	0	0	0
TAF5 WILD-TYPE	4	5	5	3	2	1	3	2

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S566. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TAF5 MUTATED	1	1	1	1
TAF5 WILD-TYPE	15	7	13	15

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S567. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TAF5 MUTATED	2	1	0	1
TAF5 WILD-TYPE	14	15	4	17

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.01 (Fisher's exact test), Q value = 1

Table S568. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	26	8	17

Figure S30. Get High-res Image Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S569. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TAF5 MUTATED	0	4	0	0	0
TAF5 WILD-TYPE	13	14	8	14	2

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S570. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	21	11	18

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0139 (Fisher's exact test), Q value = 1

Table S571. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TAF5 MUTATED	0	4	0
TAF5 WILD-TYPE	30	12	8

Figure S31. Get High-res Image Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0763 (Fisher's exact test), Q value = 1

Table S572. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GARS MUTATED	5	4	4	6
GARS WILD-TYPE	16	16	6	3

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0913 (Fisher's exact test), Q value = 1

Table S573. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GARS MUTATED	2	0	4	5	4
GARS WILD-TYPE	11	8	10	8	3

'GARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S574. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
GARS MUTATED	6	3
GARS WILD-TYPE	7	12

'GARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S575. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GARS MUTATED	2	1	4	1	0	0	1	0
GARS WILD-TYPE	3	5	1	2	3	1	2	2

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S576. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GARS MUTATED	3	1	4	7
GARS WILD-TYPE	13	7	10	9

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S577. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GARS MUTATED	2	3	2	8
GARS WILD-TYPE	14	13	2	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S578. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GARS MUTATED	6	1	8
GARS WILD-TYPE	20	10	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S579. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GARS MUTATED	3	6	4	2	0
GARS WILD-TYPE	10	12	4	12	2

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S580. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GARS MUTATED	5	2	8
GARS WILD-TYPE	16	12	11

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S581. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GARS MUTATED	6	6	3
GARS WILD-TYPE	24	10	5

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S582. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MUC5B MUTATED	8	7	3	3
MUC5B WILD-TYPE	13	13	7	6

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S583. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MUC5B MUTATED	3	3	6	4	4
MUC5B WILD-TYPE	10	5	8	9	3

'MUC5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S584. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MUC5B MUTATED	5	6
MUC5B WILD-TYPE	8	9

'MUC5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S585. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MUC5B MUTATED	2	2	2	0	2	0	2	1
MUC5B WILD-TYPE	3	4	3	3	1	1	1	1

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S586. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MUC5B MUTATED	5	3	7	5
MUC5B WILD-TYPE	11	5	7	11

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S587. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MUC5B MUTATED	4	7	2	7
MUC5B WILD-TYPE	12	9	2	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S588. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MUC5B MUTATED	8	5	7
MUC5B WILD-TYPE	18	6	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S589. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MUC5B MUTATED	3	7	4	6	0
MUC5B WILD-TYPE	10	11	4	8	2

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S590. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MUC5B MUTATED	7	5	7
MUC5B WILD-TYPE	14	9	12

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S591. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MUC5B MUTATED	9	6	4
MUC5B WILD-TYPE	21	10	4

'KIAA1984 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S592. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KIAA1984 MUTATED	2	0	1	1
KIAA1984 WILD-TYPE	19	20	9	8

'KIAA1984 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S593. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KIAA1984 MUTATED	0	1	2	1	0
KIAA1984 WILD-TYPE	13	7	12	12	7

'KIAA1984 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S594. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KIAA1984 MUTATED	0	3
KIAA1984 WILD-TYPE	13	12

'KIAA1984 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S595. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KIAA1984 MUTATED	0	2	0	0	1	0	0	0
KIAA1984 WILD-TYPE	5	4	5	3	2	1	3	2

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S596. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KIAA1984 MUTATED	1	0	3	0
KIAA1984 WILD-TYPE	15	8	11	16

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.049 (Fisher's exact test), Q value = 1

Table S597. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KIAA1984 MUTATED	0	3	1	0
KIAA1984 WILD-TYPE	16	13	3	18

Figure S32. Get High-res Image Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 1

Table S598. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KIAA1984 MUTATED	1	3	0
KIAA1984 WILD-TYPE	25	8	18

Figure S33. Get High-res Image Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S599. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KIAA1984 MUTATED	0	1	1	2	0
KIAA1984 WILD-TYPE	13	17	7	12	2

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S600. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KIAA1984 MUTATED	1	2	1
KIAA1984 WILD-TYPE	20	12	18

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S601. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KIAA1984 MUTATED	2	1	1
KIAA1984 WILD-TYPE	28	15	7

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S602. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SRPX MUTATED	1	2	0	0
SRPX WILD-TYPE	20	18	10	9

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S603. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SRPX MUTATED	0	2	0	1	0
SRPX WILD-TYPE	13	6	14	12	7

'SRPX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S604. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SRPX MUTATED	1	1
SRPX WILD-TYPE	12	14

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.619 (Fisher's exact test), Q value = 1

Table S605. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SRPX MUTATED	0	1	1	1
SRPX WILD-TYPE	16	7	13	15

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S606. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SRPX MUTATED	1	1	0	1
SRPX WILD-TYPE	15	15	4	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S607. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	25	10	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S608. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SRPX MUTATED	1	2	0	0	0
SRPX WILD-TYPE	12	16	8	14	2

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S609. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	20	13	18

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S610. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SRPX MUTATED	1	2	0
SRPX WILD-TYPE	29	14	8

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S611. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TNIP2 MUTATED	3	1	0	1
TNIP2 WILD-TYPE	18	19	10	8

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S612. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TNIP2 MUTATED	1	1	2	0	0
TNIP2 WILD-TYPE	12	7	12	13	7

'TNIP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S613. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TNIP2 MUTATED	0	1
TNIP2 WILD-TYPE	13	14

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S614. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TNIP2 MUTATED	1	0	2	1
TNIP2 WILD-TYPE	15	8	12	15

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S615. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TNIP2 MUTATED	1	2	0	1
TNIP2 WILD-TYPE	15	14	4	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S616. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	24	10	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S617. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TNIP2 MUTATED	1	0	1	2	0
TNIP2 WILD-TYPE	12	18	7	12	2

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S618. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	19	13	18

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S619. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TNIP2 MUTATED	3	0	1
TNIP2 WILD-TYPE	27	16	7

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S620. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IDUA MUTATED	5	1	1	1
IDUA WILD-TYPE	16	19	9	8

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S621. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
IDUA MUTATED	2	1	3	1	0
IDUA WILD-TYPE	11	7	11	12	7

'IDUA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S622. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
IDUA MUTATED	2	2
IDUA WILD-TYPE	11	13

'IDUA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S623. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
IDUA MUTATED	1	0	1	1	1	0	0	0
IDUA WILD-TYPE	4	6	4	2	2	1	3	2

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S624. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
IDUA MUTATED	3	2	1	1
IDUA WILD-TYPE	13	6	13	15

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S625. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IDUA MUTATED	3	3	0	1
IDUA WILD-TYPE	13	13	4	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 1

Table S626. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
IDUA MUTATED	3	3	1
IDUA WILD-TYPE	23	8	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S627. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IDUA MUTATED	1	2	0	4	0
IDUA WILD-TYPE	12	16	8	10	2

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S628. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
IDUA MUTATED	4	2	1
IDUA WILD-TYPE	17	12	18

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S629. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
IDUA MUTATED	5	2	0
IDUA WILD-TYPE	25	14	8

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S630. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF39 MUTATED	3	1	1	0
RNF39 WILD-TYPE	18	19	9	9

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S631. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RNF39 MUTATED	1	2	2	0	0
RNF39 WILD-TYPE	12	6	12	13	7

'RNF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S632. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RNF39 MUTATED	1	3
RNF39 WILD-TYPE	12	12

'RNF39 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S633. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF39 MUTATED	1	2	0	1	0	0	0	0
RNF39 WILD-TYPE	4	4	5	2	3	1	3	2

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S634. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RNF39 MUTATED	1	1	3	0
RNF39 WILD-TYPE	15	7	11	16

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S635. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF39 MUTATED	2	3	0	0
RNF39 WILD-TYPE	14	13	4	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S636. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	23	9	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S637. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF39 MUTATED	2	1	0	2	0
RNF39 WILD-TYPE	11	17	8	12	2

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 1

Table S638. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	18	12	19

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S639. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RNF39 MUTATED	4	1	0
RNF39 WILD-TYPE	26	15	8

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S640. Gene #67: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PABPC1 MUTATED	1	1	2	0
PABPC1 WILD-TYPE	20	19	8	9

'PABPC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S641. Gene #67: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PABPC1 MUTATED	1	0
PABPC1 WILD-TYPE	12	15

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S642. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SCRT1 MUTATED	2	1	0	0
SCRT1 WILD-TYPE	19	19	10	9

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S643. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SCRT1 MUTATED	2	0	0	1	0
SCRT1 WILD-TYPE	11	8	14	12	7

'SCRT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S644. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SCRT1 MUTATED	1	0
SCRT1 WILD-TYPE	12	15

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S645. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SCRT1 MUTATED	2	0	1	0
SCRT1 WILD-TYPE	14	8	13	16

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S646. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SCRT1 MUTATED	2	0	0	1
SCRT1 WILD-TYPE	14	16	4	17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S647. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	24	10	18

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S648. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SCRT1 MUTATED	0	1	1	1	0
SCRT1 WILD-TYPE	13	17	7	13	2

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S649. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	19	13	19

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S650. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	28	15	8

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S651. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAP1S MUTATED	0	2	1	2
MAP1S WILD-TYPE	21	18	9	7

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S652. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAP1S MUTATED	1	1	0	3	0
MAP1S WILD-TYPE	12	7	14	10	7

'MAP1S MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S653. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MAP1S MUTATED	2	2
MAP1S WILD-TYPE	11	13

'MAP1S MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S654. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAP1S MUTATED	2	0	2	0	0	0	0	0
MAP1S WILD-TYPE	3	6	3	3	3	1	3	2

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S655. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAP1S MUTATED	1	1	0	3
MAP1S WILD-TYPE	15	7	14	13

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S656. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP1S MUTATED	2	1	0	2
MAP1S WILD-TYPE	14	15	4	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S657. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAP1S MUTATED	2	1	2
MAP1S WILD-TYPE	24	10	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S658. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP1S MUTATED	2	2	0	1	0
MAP1S WILD-TYPE	11	16	8	13	2

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S659. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAP1S MUTATED	3	0	2
MAP1S WILD-TYPE	18	14	17

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S660. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAP1S MUTATED	3	2	0
MAP1S WILD-TYPE	27	14	8

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S661. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NF1 MUTATED	4	1	0	2
NF1 WILD-TYPE	17	19	10	7

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S662. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NF1 MUTATED	2	0	2	2	1
NF1 WILD-TYPE	11	8	12	11	6

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S663. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NF1 MUTATED	0	4
NF1 WILD-TYPE	13	11

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S664. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
NF1 MUTATED	1	0	0	1	1	0	0	1
NF1 WILD-TYPE	4	6	5	2	2	1	3	1

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S665. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NF1 MUTATED	4	0	2	1
NF1 WILD-TYPE	12	8	12	15

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S666. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NF1 MUTATED	2	2	2	1
NF1 WILD-TYPE	14	14	2	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S667. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NF1 MUTATED	2	3	2
NF1 WILD-TYPE	24	8	16

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S668. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NF1 MUTATED	1	2	1	3	0
NF1 WILD-TYPE	12	16	7	11	2

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S669. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NF1 MUTATED	3	2	2
NF1 WILD-TYPE	18	12	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0976 (Fisher's exact test), Q value = 1

Table S670. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NF1 MUTATED	3	1	3
NF1 WILD-TYPE	27	15	5

'AKAP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S671. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AKAP2 MUTATED	1	0	1	2
AKAP2 WILD-TYPE	20	20	9	7

'AKAP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S672. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AKAP2 MUTATED	0	0	2	2	0
AKAP2 WILD-TYPE	13	8	12	11	7

'AKAP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S673. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
AKAP2 MUTATED	1	2
AKAP2 WILD-TYPE	12	13

'AKAP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S674. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AKAP2 MUTATED	0	1	1	0	0	0	0	1
AKAP2 WILD-TYPE	5	5	4	3	3	1	3	1

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S675. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AKAP2 MUTATED	1	0	2	1
AKAP2 WILD-TYPE	15	8	12	15

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S676. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AKAP2 MUTATED	0	2	1	1
AKAP2 WILD-TYPE	16	14	3	17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S677. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AKAP2 MUTATED	1	1	2
AKAP2 WILD-TYPE	25	10	16

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S678. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AKAP2 MUTATED	1	3	0	0	0
AKAP2 WILD-TYPE	12	15	8	14	2

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S679. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AKAP2 MUTATED	1	1	2
AKAP2 WILD-TYPE	20	13	17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S680. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AKAP2 MUTATED	1	2	1
AKAP2 WILD-TYPE	29	14	7

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S681. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOTCH2 MUTATED	4	1	0	0
NOTCH2 WILD-TYPE	17	19	10	9

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S682. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOTCH2 MUTATED	1	0	2	1	0
NOTCH2 WILD-TYPE	12	8	12	12	7

'NOTCH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NOTCH2 MUTATED	1	1
NOTCH2 WILD-TYPE	12	14

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S684. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOTCH2 MUTATED	2	1	1	0
NOTCH2 WILD-TYPE	14	7	13	16

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S685. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOTCH2 MUTATED	1	2	1	0
NOTCH2 WILD-TYPE	15	14	3	18

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 1

Table S686. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOTCH2 MUTATED	1	3	0
NOTCH2 WILD-TYPE	25	8	18

Figure S34. Get High-res Image Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S687. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOTCH2 MUTATED	0	1	0	3	0
NOTCH2 WILD-TYPE	13	17	8	11	2

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S688. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOTCH2 MUTATED	1	2	1
NOTCH2 WILD-TYPE	20	12	18

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S689. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOTCH2 MUTATED	2	1	1
NOTCH2 WILD-TYPE	28	15	7

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S690. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FANK1 MUTATED	2	1	1	0
FANK1 WILD-TYPE	19	19	9	9

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S691. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FANK1 MUTATED	0	1	0	1	1
FANK1 WILD-TYPE	13	7	14	12	6

'FANK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S692. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
FANK1 MUTATED	0	1
FANK1 WILD-TYPE	13	14

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S693. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	15	7	14	15

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S694. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FANK1 MUTATED	1	0	1	1
FANK1 WILD-TYPE	15	16	3	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S695. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	25	10	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S696. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FANK1 MUTATED	0	0	1	2	0
FANK1 WILD-TYPE	13	18	7	12	2

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S697. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FANK1 MUTATED	2	0	1
FANK1 WILD-TYPE	19	14	18

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S698. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FANK1 MUTATED	2	0	1
FANK1 WILD-TYPE	28	16	7

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0503 (Fisher's exact test), Q value = 1

Table S699. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NEFH MUTATED	5	0	1	0
NEFH WILD-TYPE	16	20	9	9

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S700. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NEFH MUTATED	3	0	0	1	0
NEFH WILD-TYPE	10	8	14	12	7

'NEFH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S701. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NEFH MUTATED	0	2
NEFH WILD-TYPE	13	13

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S702. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NEFH MUTATED	3	0	0	0
NEFH WILD-TYPE	13	8	14	16

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0503 (Fisher's exact test), Q value = 1

Table S703. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NEFH MUTATED	2	0	1	0
NEFH WILD-TYPE	14	16	3	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S704. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NEFH MUTATED	3	1	0
NEFH WILD-TYPE	23	10	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S705. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NEFH MUTATED	1	0	0	3	0
NEFH WILD-TYPE	12	18	8	11	2

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S706. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NEFH MUTATED	1	2	1
NEFH WILD-TYPE	20	12	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S707. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NEFH MUTATED	3	0	1
NEFH WILD-TYPE	27	16	7

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S708. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NPTX1 MUTATED	1	1	0	1
NPTX1 WILD-TYPE	20	19	10	8

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S709. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NPTX1 MUTATED	1	0	1	1	0
NPTX1 WILD-TYPE	12	8	13	12	7

'NPTX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S710. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NPTX1 MUTATED	1	0
NPTX1 WILD-TYPE	12	15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S711. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NPTX1 MUTATED	1	0	1	1
NPTX1 WILD-TYPE	15	8	13	15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S712. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NPTX1 MUTATED	1	0	0	2
NPTX1 WILD-TYPE	15	16	4	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S713. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NPTX1 MUTATED	1	0	2
NPTX1 WILD-TYPE	25	11	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S714. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NPTX1 MUTATED	0	1	1	1	0
NPTX1 WILD-TYPE	13	17	7	13	2

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S715. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NPTX1 MUTATED	0	1	2
NPTX1 WILD-TYPE	21	13	17

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S716. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NPTX1 MUTATED	1	1	1
NPTX1 WILD-TYPE	29	15	7

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S717. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KBTBD13 MUTATED	5	3	0	1
KBTBD13 WILD-TYPE	16	17	10	8

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S718. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KBTBD13 MUTATED	3	1	0	2	3
KBTBD13 WILD-TYPE	10	7	14	11	4

'KBTBD13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S719. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KBTBD13 MUTATED	3	1
KBTBD13 WILD-TYPE	10	14

'KBTBD13 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S720. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KBTBD13 MUTATED	1	0	1	1	1	0	0	0
KBTBD13 WILD-TYPE	4	6	4	2	2	1	3	2

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S721. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KBTBD13 MUTATED	4	1	1	3
KBTBD13 WILD-TYPE	12	7	13	13

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S722. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KBTBD13 MUTATED	4	0	1	4
KBTBD13 WILD-TYPE	12	16	3	14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S723. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	22	9	15

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S724. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KBTBD13 MUTATED	0	4	2	3	0
KBTBD13 WILD-TYPE	13	14	6	11	2

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S725. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	17	12	16

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S726. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KBTBD13 MUTATED	4	4	1
KBTBD13 WILD-TYPE	26	12	7

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S727. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RASIP1 MUTATED	1	3	2	0
RASIP1 WILD-TYPE	20	17	8	9

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S728. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RASIP1 MUTATED	2	2	2	0	0
RASIP1 WILD-TYPE	11	6	12	13	7

'RASIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S729. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RASIP1 MUTATED	1	1
RASIP1 WILD-TYPE	12	14

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0425 (Fisher's exact test), Q value = 1

Table S730. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RASIP1 MUTATED	2	3	1	0
RASIP1 WILD-TYPE	14	5	13	16

Figure S35. Get High-res Image Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S731. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RASIP1 MUTATED	3	3	0	0
RASIP1 WILD-TYPE	13	13	4	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0563 (Fisher's exact test), Q value = 1

Table S732. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RASIP1 MUTATED	3	3	0
RASIP1 WILD-TYPE	23	8	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S733. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RASIP1 MUTATED	1	2	0	3	0
RASIP1 WILD-TYPE	12	16	8	11	2

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S734. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RASIP1 MUTATED	2	3	1
RASIP1 WILD-TYPE	19	11	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S735. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RASIP1 MUTATED	4	2	0
RASIP1 WILD-TYPE	26	14	8

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S736. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AR MUTATED	2	0	1	1
AR WILD-TYPE	19	20	9	8

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S737. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AR MUTATED	2	0	1	0	0
AR WILD-TYPE	11	8	13	13	7

'AR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S738. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
AR MUTATED	1	2
AR WILD-TYPE	12	13

'AR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S739. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AR MUTATED	1	1	0	0	1	0	0	0
AR WILD-TYPE	4	5	5	3	2	1	3	2

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S740. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AR MUTATED	2	0	1	0
AR WILD-TYPE	14	8	13	16

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S741. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AR MUTATED	2	1	0	0
AR WILD-TYPE	14	15	4	18

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S742. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AR MUTATED	2	1	0
AR WILD-TYPE	24	10	18

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S743. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AR MUTATED	1	1	0	1	0
AR WILD-TYPE	12	17	8	13	2

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S744. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AR MUTATED	1	2	0
AR WILD-TYPE	20	12	19

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S745. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AR MUTATED	2	1	0
AR WILD-TYPE	28	15	8

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S746. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KNDC1 MUTATED	1	4	2	2
KNDC1 WILD-TYPE	20	16	8	7

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0652 (Fisher's exact test), Q value = 1

Table S747. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KNDC1 MUTATED	0	2	2	1	3
KNDC1 WILD-TYPE	13	6	12	12	4

'KNDC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S748. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KNDC1 MUTATED	1	2
KNDC1 WILD-TYPE	12	13

'KNDC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S749. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KNDC1 MUTATED	2	0	1	0	0	0	0	0
KNDC1 WILD-TYPE	3	6	4	3	3	1	3	2

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.026 (Fisher's exact test), Q value = 1

Table S750. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KNDC1 MUTATED	0	3	1	4
KNDC1 WILD-TYPE	16	5	13	12

Figure S36. Get High-res Image Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S751. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KNDC1 MUTATED	1	2	0	5
KNDC1 WILD-TYPE	15	14	4	13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S752. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KNDC1 MUTATED	2	2	4
KNDC1 WILD-TYPE	24	9	14

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S753. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KNDC1 MUTATED	1	3	3	1	0
KNDC1 WILD-TYPE	12	15	5	13	2

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S754. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KNDC1 MUTATED	4	0	4
KNDC1 WILD-TYPE	17	14	15

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S755. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KNDC1 MUTATED	3	3	2
KNDC1 WILD-TYPE	27	13	6

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S756. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SEZ6L2 MUTATED	2	4	0	2
SEZ6L2 WILD-TYPE	19	16	10	7

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S757. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SEZ6L2 MUTATED	2	2	1	1	0
SEZ6L2 WILD-TYPE	11	6	13	12	7

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S758. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SEZ6L2 MUTATED	1	2
SEZ6L2 WILD-TYPE	12	13

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S759. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEZ6L2 MUTATED	0	2	1	0	0	0	0	0
SEZ6L2 WILD-TYPE	5	4	4	3	3	1	3	2

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S760. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SEZ6L2 MUTATED	2	0	2	2
SEZ6L2 WILD-TYPE	14	8	12	14

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEZ6L2 MUTATED	2	2	0	2
SEZ6L2 WILD-TYPE	14	14	4	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.462 (Fisher's exact test), Q value = 1

Table S762. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SEZ6L2 MUTATED	4	0	2
SEZ6L2 WILD-TYPE	22	11	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S763. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEZ6L2 MUTATED	1	1	2	2	0
SEZ6L2 WILD-TYPE	12	17	6	12	2

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S764. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SEZ6L2 MUTATED	2	2	2
SEZ6L2 WILD-TYPE	19	12	17

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S765. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SEZ6L2 MUTATED	4	1	1
SEZ6L2 WILD-TYPE	26	15	7

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S766. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
VARS MUTATED	2	2	1	1
VARS WILD-TYPE	19	18	9	8

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S767. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
VARS MUTATED	0	1	3	2	0
VARS WILD-TYPE	13	7	11	11	7

'VARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S768. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
VARS MUTATED	0	3
VARS WILD-TYPE	13	12

'VARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S769. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
VARS MUTATED	0	1	0	0	1	0	0	1
VARS WILD-TYPE	5	5	5	3	2	1	3	1

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S770. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
VARS MUTATED	1	0	4	1
VARS WILD-TYPE	15	8	10	15

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0665 (Fisher's exact test), Q value = 1

Table S771. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
VARS MUTATED	0	4	1	1
VARS WILD-TYPE	16	12	3	17

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S772. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
VARS MUTATED	2	2	2
VARS WILD-TYPE	24	9	16

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S773. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
VARS MUTATED	2	2	0	2	0
VARS WILD-TYPE	11	16	8	12	2

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S774. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
VARS MUTATED	2	1	3
VARS WILD-TYPE	19	13	16

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S775. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
VARS MUTATED	3	2	1
VARS WILD-TYPE	27	14	7

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S776. Gene #82: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IER5 MUTATED	3	0	0	0
IER5 WILD-TYPE	18	20	10	9

'IER5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S777. Gene #82: 'IER5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
IER5 MUTATED	1	0
IER5 WILD-TYPE	12	15

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S778. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NMU MUTATED	1	2	1	0
NMU WILD-TYPE	20	18	9	9

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S779. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NMU MUTATED	1	1	1	1	0
NMU WILD-TYPE	12	7	13	12	7

'NMU MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S780. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NMU MUTATED	1	0
NMU WILD-TYPE	12	15

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0701 (Fisher's exact test), Q value = 1

Table S781. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	6	14	15

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S782. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	14	4	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S783. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NMU MUTATED	2	1	1
NMU WILD-TYPE	24	10	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S784. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NMU MUTATED	2	2	0	0	0
NMU WILD-TYPE	11	16	8	14	2

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S785. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NMU MUTATED	1	1	2
NMU WILD-TYPE	20	13	17

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S786. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NMU MUTATED	2	2	0
NMU WILD-TYPE	28	14	8

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 1

Table S787. Gene #84: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TMEM189 MUTATED	3	0	0	0
TMEM189 WILD-TYPE	18	20	10	9

'TMEM189 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S788. Gene #84: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
TMEM189 MUTATED	1	0
TMEM189 WILD-TYPE	12	15

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S789. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ADAD2 MUTATED	2	0	1	1
ADAD2 WILD-TYPE	19	20	9	8

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S790. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ADAD2 MUTATED	0	0	2	1	1
ADAD2 WILD-TYPE	13	8	12	12	6

'ADAD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S791. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ADAD2 MUTATED	0	1
ADAD2 WILD-TYPE	13	14

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S792. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ADAD2 MUTATED	1	0	2	1
ADAD2 WILD-TYPE	15	8	12	15

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S793. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAD2 MUTATED	0	2	1	1
ADAD2 WILD-TYPE	16	14	3	17

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00898 (Fisher's exact test), Q value = 1

Table S794. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	26	8	17

Figure S37. Get High-res Image Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S795. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAD2 MUTATED	0	3	0	1	0
ADAD2 WILD-TYPE	13	15	8	13	2

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0558 (Fisher's exact test), Q value = 1

Table S796. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	21	11	18

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S797. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ADAD2 MUTATED	1	2	1
ADAD2 WILD-TYPE	29	14	7

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S798. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PLEC MUTATED	4	7	1	1
PLEC WILD-TYPE	17	13	9	8

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S799. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PLEC MUTATED	2	2	1	3	2
PLEC WILD-TYPE	11	6	13	10	5

'PLEC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S800. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PLEC MUTATED	1	4
PLEC WILD-TYPE	12	11

'PLEC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.046 (Fisher's exact test), Q value = 1

Table S801. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLEC MUTATED	0	4	0	0	0	0	1	0
PLEC WILD-TYPE	5	2	5	3	3	1	2	2

Figure S38. Get High-res Image Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S802. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PLEC MUTATED	2	0	5	3
PLEC WILD-TYPE	14	8	9	13

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S803. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLEC MUTATED	2	4	0	4
PLEC WILD-TYPE	14	12	4	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S804. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PLEC MUTATED	6	2	2
PLEC WILD-TYPE	20	9	16

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S805. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLEC MUTATED	4	2	2	2	0
PLEC WILD-TYPE	9	16	6	12	2

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S806. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PLEC MUTATED	6	3	1
PLEC WILD-TYPE	15	11	18

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S807. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PLEC MUTATED	7	2	1
PLEC WILD-TYPE	23	14	7

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S808. Gene #87: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RGMB MUTATED	2	2	2	0
RGMB WILD-TYPE	19	18	8	9

'RGMB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S809. Gene #87: 'RGMB MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RGMB MUTATED	1	1
RGMB WILD-TYPE	12	14

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S810. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CLIC6 MUTATED	2	3	0	0
CLIC6 WILD-TYPE	19	17	10	9

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S811. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CLIC6 MUTATED	1	1	1	1	0
CLIC6 WILD-TYPE	12	7	13	12	7

'CLIC6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S812. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CLIC6 MUTATED	2	0
CLIC6 WILD-TYPE	11	15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S813. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CLIC6 MUTATED	2	1	0	1
CLIC6 WILD-TYPE	14	7	14	15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S814. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLIC6 MUTATED	2	1	1	0
CLIC6 WILD-TYPE	14	15	3	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S815. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	24	9	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S816. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLIC6 MUTATED	0	1	1	2	0
CLIC6 WILD-TYPE	13	17	7	12	2

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S817. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	19	12	19

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S818. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CLIC6 MUTATED	3	1	0
CLIC6 WILD-TYPE	27	15	8

'ZNF814 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S819. Gene #89: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF814 MUTATED	1	1	1	0
ZNF814 WILD-TYPE	20	19	9	9

'ZNF814 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S820. Gene #89: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ZNF814 MUTATED	1	1
ZNF814 WILD-TYPE	12	14

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S821. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DSPP MUTATED	4	4	1	0
DSPP WILD-TYPE	17	16	9	9

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0612 (Fisher's exact test), Q value = 1

Table S822. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
DSPP MUTATED	1	4	1	3	0
DSPP WILD-TYPE	12	4	13	10	7

'DSPP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S823. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
DSPP MUTATED	2	2
DSPP WILD-TYPE	11	13

'DSPP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S824. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
DSPP MUTATED	1	1	0	1	0	0	0	1
DSPP WILD-TYPE	4	5	5	2	3	1	3	1

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S825. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
DSPP MUTATED	3	1	2	3
DSPP WILD-TYPE	13	7	12	13

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S826. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DSPP MUTATED	4	1	1	3
DSPP WILD-TYPE	12	15	3	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S827. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
DSPP MUTATED	3	3	3
DSPP WILD-TYPE	23	8	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S828. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DSPP MUTATED	1	4	1	2	1
DSPP WILD-TYPE	12	14	7	12	1

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S829. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
DSPP MUTATED	3	3	3
DSPP WILD-TYPE	18	11	16

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S830. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
DSPP MUTATED	5	3	1
DSPP WILD-TYPE	25	13	7

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S831. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AMDHD1 MUTATED	5	2	1	2
AMDHD1 WILD-TYPE	16	18	9	7

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S832. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AMDHD1 MUTATED	1	1	4	2	1
AMDHD1 WILD-TYPE	12	7	10	11	6

'AMDHD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S833. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
AMDHD1 MUTATED	0	3
AMDHD1 WILD-TYPE	13	12

'AMDHD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S834. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AMDHD1 MUTATED	1	0	0	0	1	0	0	1
AMDHD1 WILD-TYPE	4	6	5	3	2	1	3	1

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S835. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AMDHD1 MUTATED	3	2	3	1
AMDHD1 WILD-TYPE	13	6	11	15

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S836. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AMDHD1 MUTATED	1	4	2	2
AMDHD1 WILD-TYPE	15	12	2	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S837. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AMDHD1 MUTATED	3	4	2
AMDHD1 WILD-TYPE	23	7	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S838. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AMDHD1 MUTATED	1	4	1	3	0
AMDHD1 WILD-TYPE	12	14	7	11	2

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S839. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AMDHD1 MUTATED	3	2	4
AMDHD1 WILD-TYPE	18	12	15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S840. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AMDHD1 MUTATED	4	3	2
AMDHD1 WILD-TYPE	26	13	6

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S841. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CRIPAK MUTATED	2	4	1	3
CRIPAK WILD-TYPE	19	16	9	6

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S842. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CRIPAK MUTATED	2	1	2	2	2
CRIPAK WILD-TYPE	11	7	12	11	5

'CRIPAK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S843. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CRIPAK MUTATED	1	3
CRIPAK WILD-TYPE	12	12

'CRIPAK MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S844. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CRIPAK MUTATED	1	2	1	0	0	0	0	0
CRIPAK WILD-TYPE	4	4	4	3	3	1	3	2

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S845. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CRIPAK MUTATED	2	0	3	4
CRIPAK WILD-TYPE	14	8	11	12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S846. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CRIPAK MUTATED	2	2	1	4
CRIPAK WILD-TYPE	14	14	3	14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S847. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	21	10	15

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S848. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CRIPAK MUTATED	1	4	3	1	0
CRIPAK WILD-TYPE	12	14	5	13	2

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S849. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	16	13	16

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S850. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CRIPAK MUTATED	5	4	0
CRIPAK WILD-TYPE	25	12	8

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S851. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOM1 MUTATED	2	2	1	1
NOM1 WILD-TYPE	19	18	9	8

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S852. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOM1 MUTATED	1	1	1	0	2
NOM1 WILD-TYPE	12	7	13	13	5

'NOM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S853. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NOM1 MUTATED	1	1
NOM1 WILD-TYPE	12	14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S854. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOM1 MUTATED	2	0	1	2
NOM1 WILD-TYPE	14	8	13	14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S855. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOM1 MUTATED	2	1	0	2
NOM1 WILD-TYPE	14	15	4	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S856. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOM1 MUTATED	2	1	2
NOM1 WILD-TYPE	24	10	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S857. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOM1 MUTATED	2	1	1	1	0
NOM1 WILD-TYPE	11	17	7	13	2

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S858. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOM1 MUTATED	3	0	2
NOM1 WILD-TYPE	18	14	17

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S859. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOM1 MUTATED	3	1	1
NOM1 WILD-TYPE	27	15	7

'MAP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S860. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAP7 MUTATED	2	1	0	0
MAP7 WILD-TYPE	19	19	10	9

'MAP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S861. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAP7 MUTATED	1	0	0	1	1
MAP7 WILD-TYPE	12	8	14	12	6

'MAP7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S862. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MAP7 MUTATED	1	0
MAP7 WILD-TYPE	12	15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S863. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAP7 MUTATED	1	0	1	1
MAP7 WILD-TYPE	15	8	13	15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S864. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP7 MUTATED	1	0	0	2
MAP7 WILD-TYPE	15	16	4	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S865. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAP7 MUTATED	1	0	2
MAP7 WILD-TYPE	25	11	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S866. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP7 MUTATED	0	1	1	1	0
MAP7 WILD-TYPE	13	17	7	13	2

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S867. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAP7 MUTATED	1	1	1
MAP7 WILD-TYPE	20	13	18

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S868. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAP7 MUTATED	1	1	1
MAP7 WILD-TYPE	29	15	7

'PTX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S869. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PTX4 MUTATED	1	1	1	0
PTX4 WILD-TYPE	20	19	9	9

'PTX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S870. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PTX4 MUTATED	1	0	1	1	0
PTX4 WILD-TYPE	12	8	13	12	7

'PTX4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S871. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PTX4 MUTATED	0	1
PTX4 WILD-TYPE	13	14

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S872. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PTX4 MUTATED	2	0	1	0
PTX4 WILD-TYPE	14	8	13	16

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 1

Table S873. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PTX4 MUTATED	1	1	1	0
PTX4 WILD-TYPE	15	15	3	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S874. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PTX4 MUTATED	2	1	0
PTX4 WILD-TYPE	24	10	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PTX4 MUTATED	1	1	0	1	0
PTX4 WILD-TYPE	12	17	8	13	2

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S876. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PTX4 MUTATED	1	2	0
PTX4 WILD-TYPE	20	12	19

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S877. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PTX4 MUTATED	2	0	1
PTX4 WILD-TYPE	28	16	7

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S878. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LRP11 MUTATED	2	2	1	0
LRP11 WILD-TYPE	19	18	9	9

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0812 (Fisher's exact test), Q value = 1

Table S879. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LRP11 MUTATED	1	0	4	0	0
LRP11 WILD-TYPE	12	8	10	13	7

'LRP11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S880. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
LRP11 MUTATED	0	1
LRP11 WILD-TYPE	13	14

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S881. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LRP11 MUTATED	1	1	2	1
LRP11 WILD-TYPE	15	7	12	15

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S882. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRP11 MUTATED	1	3	0	1
LRP11 WILD-TYPE	15	13	4	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S883. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	24	9	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S884. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRP11 MUTATED	1	2	0	2	0
LRP11 WILD-TYPE	12	16	8	12	2

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S885. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	19	12	18

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S886. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LRP11 MUTATED	3	2	0
LRP11 WILD-TYPE	27	14	8

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S887. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PDCD6 MUTATED	0	1	1	1
PDCD6 WILD-TYPE	21	19	9	8

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S888. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PDCD6 MUTATED	1	0	0	1	1
PDCD6 WILD-TYPE	12	8	14	12	6

'PDCD6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S889. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PDCD6 MUTATED	1	0
PDCD6 WILD-TYPE	12	15

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S890. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PDCD6 MUTATED	2	0	1
PDCD6 WILD-TYPE	24	11	17

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S891. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PDCD6 MUTATED	1	1	1	0	0
PDCD6 WILD-TYPE	12	17	7	14	2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S892. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PDCD6 MUTATED	1	1	1
PDCD6 WILD-TYPE	20	13	18

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S893. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PDCD6 MUTATED	2	1	0
PDCD6 WILD-TYPE	28	15	8

'SHOX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S894. Gene #98: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SHOX2 MUTATED	2	0	0	1
SHOX2 WILD-TYPE	19	20	10	8

'SHOX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S895. Gene #98: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SHOX2 MUTATED	1	0
SHOX2 WILD-TYPE	12	15

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S896. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	20	19	9	8

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S897. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
UQCRFS1 MUTATED	2	1	2	0	0
UQCRFS1 WILD-TYPE	11	7	12	13	7

'UQCRFS1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S898. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
UQCRFS1 MUTATED	0	2
UQCRFS1 WILD-TYPE	13	13

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S899. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	15	7	13	15

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S900. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
UQCRFS1 MUTATED	1	2	0	1
UQCRFS1 WILD-TYPE	15	14	4	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S901. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	22	11	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S902. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
UQCRFS1 MUTATED	3	0	1	1	0
UQCRFS1 WILD-TYPE	10	18	7	13	2

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S903. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
UQCRFS1 MUTATED	2	2	1
UQCRFS1 WILD-TYPE	19	12	18

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S904. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	26	16	7

'CTBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S905. Gene #100: 'CTBP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CTBP2 MUTATED	1	2	0	0
CTBP2 WILD-TYPE	20	18	10	9

'CTBP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S906. Gene #100: 'CTBP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CTBP2 MUTATED	0	1
CTBP2 WILD-TYPE	13	14

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S907. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PRKAR1A MUTATED	2	1	2	1
PRKAR1A WILD-TYPE	19	19	8	8

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S908. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PRKAR1A MUTATED	1	1	2	1	1
PRKAR1A WILD-TYPE	12	7	12	12	6

'PRKAR1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S909. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PRKAR1A MUTATED	1	3
PRKAR1A WILD-TYPE	12	12

'PRKAR1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S910. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PRKAR1A MUTATED	1	2	0	0	1	0	0	0
PRKAR1A WILD-TYPE	4	4	5	3	2	1	3	2

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S911. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PRKAR1A MUTATED	2	1	3	0
PRKAR1A WILD-TYPE	14	7	11	16

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S912. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRKAR1A MUTATED	1	3	1	1
PRKAR1A WILD-TYPE	15	13	3	17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S913. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	21	10	18

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S914. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRKAR1A MUTATED	3	1	1	1	0
PRKAR1A WILD-TYPE	10	17	7	13	2

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0481 (Fisher's exact test), Q value = 1

Table S915. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	16	13	19

Figure S39. Get High-res Image Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S916. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	25	15	8

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S917. Gene #102: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
JMJD4 MUTATED	1	1	1	0
JMJD4 WILD-TYPE	20	19	9	9

'JMJD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S918. Gene #102: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
JMJD4 MUTATED	0	2
JMJD4 WILD-TYPE	13	13

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S919. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HSD17B1 MUTATED	2	2	0	0
HSD17B1 WILD-TYPE	19	18	10	9

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0499 (Fisher's exact test), Q value = 1

Table S920. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HSD17B1 MUTATED	0	0	0	3	1
HSD17B1 WILD-TYPE	13	8	14	10	6

Figure S40. Get High-res Image Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'HSD17B1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S921. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
HSD17B1 MUTATED	2	1
HSD17B1 WILD-TYPE	11	14

'HSD17B1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S922. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
HSD17B1 MUTATED	0	0	1	0	1	0	1	0
HSD17B1 WILD-TYPE	5	6	4	3	2	1	2	2

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S923. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HSD17B1 MUTATED	2	0	1	1
HSD17B1 WILD-TYPE	14	8	13	15

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00799 (Fisher's exact test), Q value = 1

Table S924. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HSD17B1 MUTATED	0	0	2	2
HSD17B1 WILD-TYPE	16	16	2	16

Figure S41. Get High-res Image Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S925. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	24	10	17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S926. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HSD17B1 MUTATED	1	1	0	2	0
HSD17B1 WILD-TYPE	12	17	8	12	2

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S927. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HSD17B1 MUTATED	2	0	2
HSD17B1 WILD-TYPE	19	14	17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S928. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	28	15	7

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S929. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
COQ2 MUTATED	1	1	1	2
COQ2 WILD-TYPE	20	19	9	7

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S930. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
COQ2 MUTATED	0	1	1	1	1
COQ2 WILD-TYPE	13	7	13	12	6

'COQ2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S931. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
COQ2 MUTATED	1	1
COQ2 WILD-TYPE	12	14

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S932. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
COQ2 MUTATED	0	1	2	1
COQ2 WILD-TYPE	16	7	12	15

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S933. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
COQ2 MUTATED	0	2	0	2
COQ2 WILD-TYPE	16	14	4	16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S934. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
COQ2 MUTATED	2	1	1
COQ2 WILD-TYPE	24	10	17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S935. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
COQ2 MUTATED	1	2	1	0	0
COQ2 WILD-TYPE	12	16	7	14	2

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S936. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
COQ2 MUTATED	2	0	2
COQ2 WILD-TYPE	19	14	17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S937. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
COQ2 MUTATED	2	2	0
COQ2 WILD-TYPE	28	14	8

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S938. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FEZ2 MUTATED	0	2	1	0
FEZ2 WILD-TYPE	21	18	9	9

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S939. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FEZ2 MUTATED	0	1	1	0	1
FEZ2 WILD-TYPE	13	7	13	13	6

'FEZ2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S940. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
FEZ2 MUTATED	0	1
FEZ2 WILD-TYPE	13	14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S941. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FEZ2 MUTATED	0	1	0	2
FEZ2 WILD-TYPE	16	7	14	14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S942. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FEZ2 MUTATED	1	0	0	2
FEZ2 WILD-TYPE	15	16	4	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S943. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FEZ2 MUTATED	0	1	2
FEZ2 WILD-TYPE	26	10	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S944. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FEZ2 MUTATED	0	1	1	1	0
FEZ2 WILD-TYPE	13	17	7	13	2

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S945. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FEZ2 MUTATED	2	0	1
FEZ2 WILD-TYPE	19	14	18

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S946. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FEZ2 MUTATED	1	1	1
FEZ2 WILD-TYPE	29	15	7

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S947. Gene #106: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DLEU7 MUTATED	2	0	1	0
DLEU7 WILD-TYPE	19	20	9	9

'DLEU7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S948. Gene #106: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
DLEU7 MUTATED	0	1
DLEU7 WILD-TYPE	13	14

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S949. Gene #107: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF135 MUTATED	1	2	0	0
RNF135 WILD-TYPE	20	18	10	9

'RNF135 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S950. Gene #107: 'RNF135 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
RNF135 MUTATED	1	0
RNF135 WILD-TYPE	12	15

'SPIRE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S951. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SPIRE2 MUTATED	0	1	1	1
SPIRE2 WILD-TYPE	21	19	9	8

'SPIRE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 1

Table S952. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SPIRE2 MUTATED	1	0	0	0	2
SPIRE2 WILD-TYPE	12	8	14	13	5

Figure S42. Get High-res Image Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'SPIRE2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S953. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SPIRE2 MUTATED	1	1
SPIRE2 WILD-TYPE	12	14

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S954. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SPIRE2 MUTATED	1	0	1	1
SPIRE2 WILD-TYPE	15	8	13	15

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S955. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SPIRE2 MUTATED	1	0	0	2
SPIRE2 WILD-TYPE	15	16	4	16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S956. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SPIRE2 MUTATED	2	0	1
SPIRE2 WILD-TYPE	24	11	17

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S957. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SPIRE2 MUTATED	0	1	1	1	0
SPIRE2 WILD-TYPE	13	17	7	13	2

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S958. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SPIRE2 MUTATED	1	1	1
SPIRE2 WILD-TYPE	20	13	18

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S959. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SPIRE2 MUTATED	2	1	0
SPIRE2 WILD-TYPE	28	15	8

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S960. Gene #109: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KRTAP5-5 MUTATED	1	1	1	0
KRTAP5-5 WILD-TYPE	20	19	9	9

'SGK223 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S961. Gene #110: 'SGK223 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SGK223 MUTATED	1	2	0	0
SGK223 WILD-TYPE	20	18	10	9

'SGK223 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S962. Gene #110: 'SGK223 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
SGK223 MUTATED	1	1
SGK223 WILD-TYPE	12	14

'C9ORF66 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S963. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C9ORF66 MUTATED	2	2	1	0
C9ORF66 WILD-TYPE	19	18	9	9

'C9ORF66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S964. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C9ORF66 MUTATED	1	1	1	2	0
C9ORF66 WILD-TYPE	12	7	13	11	7

'C9ORF66 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S965. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
C9ORF66 MUTATED	1	1
C9ORF66 WILD-TYPE	12	14

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S966. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C9ORF66 MUTATED	2	1	1	1
C9ORF66 WILD-TYPE	14	7	13	15

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S967. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C9ORF66 MUTATED	1	2	1	1
C9ORF66 WILD-TYPE	15	14	3	17

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S968. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C9ORF66 MUTATED	2	2	1
C9ORF66 WILD-TYPE	24	9	17

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S969. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C9ORF66 MUTATED	1	2	0	2	0
C9ORF66 WILD-TYPE	12	16	8	12	2

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 1

Table S970. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C9ORF66 MUTATED	2	0	3
C9ORF66 WILD-TYPE	19	14	16

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S971. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C9ORF66 MUTATED	2	2	1
C9ORF66 WILD-TYPE	28	14	7

'AQP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S972. Gene #112: 'AQP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AQP7 MUTATED	1	2	0	0
AQP7 WILD-TYPE	20	18	10	9

'ADAMTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 1

Table S973. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ADAMTS7 MUTATED	0	3	0	1
ADAMTS7 WILD-TYPE	21	17	10	8

'ADAMTS7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S974. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ADAMTS7 MUTATED	0	0	1	2	1
ADAMTS7 WILD-TYPE	13	8	13	11	6

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0873 (Fisher's exact test), Q value = 1

Table S975. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
ADAMTS7 MUTATED	3	0
ADAMTS7 WILD-TYPE	10	15

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S976. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ADAMTS7 MUTATED	0	0	2	0	1	0	0	0
ADAMTS7 WILD-TYPE	5	6	3	3	2	1	3	2

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0914 (Fisher's exact test), Q value = 1

Table S977. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	7	14	13

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S978. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	15	4	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0824 (Fisher's exact test), Q value = 1

Table S979. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	26	10	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 1

Table S980. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAMTS7 MUTATED	0	3	1	0	0
ADAMTS7 WILD-TYPE	13	15	7	14	2

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S981. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	21	13	16

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S982. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ADAMTS7 MUTATED	0	3	1
ADAMTS7 WILD-TYPE	30	13	7

Figure S43. Get High-res Image Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PCDHB13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S983. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PCDHB13 MUTATED	1	1	2	1
PCDHB13 WILD-TYPE	20	19	8	8

'PCDHB13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S984. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PCDHB13 MUTATED	0	1	3	0	0
PCDHB13 WILD-TYPE	13	7	11	13	7

'PCDHB13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S985. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
PCDHB13 MUTATED	0	2
PCDHB13 WILD-TYPE	13	13

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S986. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PCDHB13 MUTATED	0	0	3	1
PCDHB13 WILD-TYPE	16	8	11	15

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S987. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PCDHB13 MUTATED	0	3	0	1
PCDHB13 WILD-TYPE	16	13	4	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S988. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	23	11	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0601 (Fisher's exact test), Q value = 1

Table S989. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PCDHB13 MUTATED	3	0	1	0	0
PCDHB13 WILD-TYPE	10	18	7	14	2

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S990. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	18	14	18

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S991. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	27	16	7

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S992. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CSGALNACT2 MUTATED	0	3	0	0
CSGALNACT2 WILD-TYPE	21	17	10	9

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 1

Table S993. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CSGALNACT2 MUTATED	1	0	0	0	2
CSGALNACT2 WILD-TYPE	12	8	14	13	5

Figure S44. Get High-res Image Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S994. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
CSGALNACT2 MUTATED	1	0
CSGALNACT2 WILD-TYPE	12	15

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S995. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	8	14	14

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S996. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	16	4	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S997. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CSGALNACT2 MUTATED	1	0	2
CSGALNACT2 WILD-TYPE	25	11	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S998. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CSGALNACT2 MUTATED	0	2	0	1	0
CSGALNACT2 WILD-TYPE	13	16	8	13	2

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S999. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CSGALNACT2 MUTATED	0	1	2
CSGALNACT2 WILD-TYPE	21	13	17

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S1000. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CSGALNACT2 MUTATED	1	2	0
CSGALNACT2 WILD-TYPE	29	14	8

'HLA-A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1001. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HLA-A MUTATED	2	1	0	0
HLA-A WILD-TYPE	19	19	10	9

'HLA-A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1002. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	8	13	12	7

'HLA-A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1003. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
HLA-A MUTATED	1	1
HLA-A WILD-TYPE	12	14

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1004. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HLA-A MUTATED	1	1	0	1
HLA-A WILD-TYPE	15	7	14	15

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S1005. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HLA-A MUTATED	1	1	1	0
HLA-A WILD-TYPE	15	15	3	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1006. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	24	11	17

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S1007. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	18	7	13	2

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1008. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	19	14	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.257 (Fisher's exact test), Q value = 1

Table S1009. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	28	16	7

'MTFMT MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1010. Gene #117: 'MTFMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MTFMT MUTATED	2	1	0	0
MTFMT WILD-TYPE	19	19	10	9

'MTFMT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1011. Gene #117: 'MTFMT MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
MTFMT MUTATED	0	1
MTFMT WILD-TYPE	13	14

'NLRP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S1012. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NLRP5 MUTATED	2	2	0	0
NLRP5 WILD-TYPE	19	18	10	9

'NLRP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S1013. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NLRP5 MUTATED	0	0	0	2	1
NLRP5 WILD-TYPE	13	8	14	11	6

'NLRP5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S1014. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
NLRP5 MUTATED	1	0
NLRP5 WILD-TYPE	12	15

'NLRP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1015. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NLRP5 MUTATED	1	0	1	1
NLRP5 WILD-TYPE	15	8	13	15

'NLRP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S1016. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NLRP5 MUTATED	0	0	1	2
NLRP5 WILD-TYPE	16	16	3	16

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1017. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NLRP5 MUTATED	1	1	1
NLRP5 WILD-TYPE	25	10	17

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1018. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NLRP5 MUTATED	1	1	1	0	0
NLRP5 WILD-TYPE	12	17	7	14	2

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1019. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NLRP5 MUTATED	1	1	1
NLRP5 WILD-TYPE	20	13	18

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0772 (Fisher's exact test), Q value = 1

Table S1020. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NLRP5 MUTATED	1	0	2
NLRP5 WILD-TYPE	29	16	6

'KCNJ11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0207 (Fisher's exact test), Q value = 1

Table S1021. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KCNJ11 MUTATED	0	1	3	0
KCNJ11 WILD-TYPE	21	19	7	9

Figure S45. Get High-res Image Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCNJ11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S1022. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KCNJ11 MUTATED	1	1	2	0	0
KCNJ11 WILD-TYPE	12	7	12	13	7

'KCNJ11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1023. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	13	15
KCNJ11 MUTATED	1	1
KCNJ11 WILD-TYPE	12	14

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S1024. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KCNJ11 MUTATED	1	1	2	0
KCNJ11 WILD-TYPE	15	7	12	16

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S1025. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KCNJ11 MUTATED	1	3	0	0
KCNJ11 WILD-TYPE	15	13	4	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S1026. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	22	11	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0536 (Fisher's exact test), Q value = 1

Table S1027. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KCNJ11 MUTATED	2	0	0	1	1
KCNJ11 WILD-TYPE	11	18	8	13	1

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 1

Table S1028. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KCNJ11 MUTATED	2	2	0
KCNJ11 WILD-TYPE	19	12	19

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 1

Table S1029. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	26	16	8

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/ACC-TP/15172905/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/ACC-TP/15087341/ACC-TP.transferedmergedcluster.txt
Number of patients = 62
Number of significantly mutated genes = 119
Number of Molecular subtypes = 10
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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