		Clinical Features	Time to Death		YEARS_TO_BIRTH		NEOPLASM_DISEASESTAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		KARNOFSKY_PERFORMANCE_SCORE		HISTOLOGICAL_TYPE		NUMBER_PACK_YEARS_SMOKED		YEAR_OF_TOBACCO_SMOKING_ONSET		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	38 (6%)	630	0.36934	1	0.20237	1	0.00318	0.103	0.00325	0.103	0.091149	0.9	0.56949	1	0.4861	1	0.2803	1	9.9999e-06	0.00158	0.3861	1	0.97403	1	0.22962	1	1	1
PBRM1	146 (22%)	522	0.29033	1	0.0066268	0.18	0.76448	1	0.36997	1	0.02216	0.376	0.49072	1	0.62202	1	0.98096	1	9.9999e-06	0.00158	NA	NA	NA	NA	0.0069499	0.183	0.2665	1
PTEN	28 (4%)	640	0.65134	1	0.66514	1	0.27359	1	0.4747	1	0.16597	1	0.23019	1	0.68462	1	0.2803	1	0.12029	0.904	1	1	0.84087	1	0.54851	1	1	1
BAP1	49 (7%)	619	8.6091e-05	0.00681	0.64923	1	3e-05	0.00316	7.9999e-05	0.00681	0.7759	1	0.0043551	0.129	0.012418	0.262	NA	NA	2e-04	0.0146	NA	NA	NA	NA	0.66825	1	0.73454	1
SETD2	58 (9%)	610	0.0093356	0.233	0.030875	0.48	0.055229	0.68	0.065969	0.763	0.42094	1	0.21609	1	0.31153	1	0.62807	1	0.068439	0.777	NA	NA	NA	NA	0.93924	1	0.50149	1
KDM5C	30 (4%)	638	0.016183	0.301	0.0096461	0.235	0.83112	1	0.81619	1	0.7846	1	1	1	0.0028598	0.101	NA	NA	0.01289	0.266	NA	NA	NA	NA	0.86769	1	0.38484	1
NEFH	15 (2%)	653	0.50769	1	0.41923	1	0.27437	1	0.23905	1	NA	NA	1	1	0.59636	1	0.2803	1	0.00141	0.0669	0.5195	1	NA	NA	0.10629	0.904	1	1
VHL	174 (26%)	494	0.1183	0.904	0.18226	1	0.35774	1	0.2638	1	0.068889	0.777	0.69514	1	0.35314	1	0.795	1	9.9999e-06	0.00158	NA	NA	NA	NA	9.9999e-06	0.00158	0.68083	1
NF2	16 (2%)	652	0.10868	0.904	0.22769	1	0.03	0.474	0.11768	0.904	4e-05	0.0038	0.04115	0.571	0.79354	1	NA	NA	0.00254	0.0927	NA	NA	NA	NA	0.056709	0.681	0.21727	1
HNRNPM	12 (2%)	656	0.32227	1	0.46517	1	0.4427	1	0.060059	0.704	0.35094	1	0.60099	1	0.76	1	0.83644	1	2e-05	0.00237	NA	NA	NA	NA	0.21668	1	1	1
MET	19 (3%)	649	0.782	1	0.84529	1	0.45806	1	0.92589	1	0.10242	0.9	1	1	1	1	NA	NA	9.9999e-06	0.00158	0.35023	1	0.76954	1	0.145	0.983	1	1
MUC5B	30 (4%)	638	0.45709	1	0.68784	1	0.4776	1	0.58035	1	0.11516	0.904	0.50964	1	0.84446	1	0.4397	1	9.9999e-06	0.00158	0.98856	1	0.78405	1	0.38625	1	1	1
KDM6A	11 (2%)	657	0.57762	1	0.055905	0.68	0.37072	1	1	1	NA	NA	0.60901	1	1	1	NA	NA	0.01584	0.301	NA	NA	NA	NA	0.00036	0.0244	1	1
TDG	5 (1%)	663	0.23669	1	0.45872	1	1	1	0.11556	0.904	0.35098	1	1	1	0.66517	1	NA	NA	0.0017	0.0701	NA	NA	NA	NA	0.47711	1	1	1
NFE2L2	10 (1%)	658	0.89745	1	0.011057	0.25	0.7635	1	0.78109	1	1	1	1	1	1	1	NA	NA	0.46186	1	NA	NA	NA	NA	0.40756	1	1	1
ATM	16 (2%)	652	0.9622	1	0.10145	0.9	0.01035	0.246	0.00141	0.0669	0.44913	1	0.43455	1	0.43227	1	NA	NA	0.12187	0.904	NA	NA	NA	NA	0.56206	1	0.50713	1
ZNF814	13 (2%)	655	0.21139	1	0.24183	1	0.14676	0.986	0.26363	1	0.43818	1	1	1	0.042126	0.571	NA	NA	0.00045	0.0285	NA	NA	NA	NA	0.33869	1	1	1
DNMT3A	10 (1%)	658	0.12941	0.93	0.95634	1	0.32947	1	0.35085	1	0.51343	1	0.60087	1	0.32321	1	NA	NA	0.46325	1	NA	NA	NA	NA	0.4084	1	0.4315	1
CDK12	9 (1%)	659	0.91159	1	0.042118	0.571	0.68107	1	0.69643	1	1	1	0.6231	1	0.50117	1	NA	NA	0.66778	1	NA	NA	NA	NA	1	1	1	1
CSGALNACT2	8 (1%)	660	0.10298	0.9	0.48616	1	0.75051	1	0.49388	1	1	1	0.60099	1	0.45575	1	NA	NA	0.00297	0.101	NA	NA	NA	NA	0.13325	0.951	1	1
PIK3CA	14 (2%)	654	0.8299	1	0.49292	1	0.58928	1	0.51055	1	1	1	0.41163	1	0.087459	0.9	NA	NA	0.39225	1	NA	NA	NA	NA	0.53605	1	0.57297	1
KIAA1751	8 (1%)	660	0.96742	1	0.101	0.9	0.6112	1	0.80952	1	0.51388	1	0.60099	1	0.72175	1	0.53337	1	1	1	NA	NA	NA	NA	0.64455	1	1	1
MTOR	32 (5%)	636	0.072541	0.8	0.041519	0.571	0.32561	1	0.65241	1	1	1	0.17421	1	0.011847	0.261	0.013645	0.276	0.0198	0.352	NA	NA	NA	NA	0.77291	1	0.71081	1
RIMBP3	5 (1%)	663	0.33223	1	0.3076	1	0.62831	1	0.089569	0.9	1	1	1	1	0.34503	1	NA	NA	0.080189	0.855	NA	NA	NA	NA	1	1	1	1
ZNF598	11 (2%)	657	0.74147	1	0.47917	1	0.60269	1	0.86723	1	0.02041	0.352	0.099711	0.9	0.34709	1	0.3614	1	2e-05	0.00237	NA	NA	NA	NA	0.21662	1	0.50713	1
GPR50	5 (1%)	663	0.45448	1	0.31149	1	0.76411	1	0.85541	1	NA	NA	1	1	0.34503	1	NA	NA	0.60366	1	NA	NA	NA	NA	0.47378	1	1	1
CCDC120	4 (1%)	664	0.19001	1	0.75103	1	0.1144	0.904	0.14863	0.986	1	1	1	1	1	1	NA	NA	0.72334	1	NA	NA	NA	NA	1	1	0.18991	1
SLC6A14	5 (1%)	663	0.72759	1	0.59895	1	0.21821	1	0.17239	1	0.092959	0.9	1	1	0.34503	1	NA	NA	0.24703	1	NA	NA	NA	NA	1	1	1	1
CYP4F11	5 (1%)	663	0.82762	1	0.49491	1	0.14104	0.983	0.04535	0.598	0.51303	1	0.46122	1	1	1	NA	NA	0.34182	1	NA	NA	NA	NA	1	1	1	1
STAG2	14 (2%)	654	0.9622	1	0.014539	0.282	0.16128	1	0.091839	0.9	1	1	0.66208	1	0.25632	1	NA	NA	0.16528	1	NA	NA	NA	NA	0.49466	1	1	1
SKI	9 (1%)	659	0.57851	1	0.74317	1	0.63042	1	0.69743	1	0.44252	1	1	1	0.72554	1	NA	NA	0.00187	0.071	0.76902	1	NA	NA	0.26752	1	1	1
ARID1A	19 (3%)	649	0.74861	1	0.77578	1	0.35117	1	0.66991	1	0.10776	0.904	0.71344	1	0.47006	1	0.58713	1	0.11334	0.904	NA	NA	NA	NA	0.01431	0.282	0.24324	1
EGFR	7 (1%)	661	0.0049895	0.139	0.70478	1	0.01229	0.262	0.0034	0.104	0.44009	1	0.26314	1	0.4319	1	NA	NA	0.25997	1	NA	NA	NA	NA	1	1	1	1
DPCR1	8 (1%)	660	0.60711	1	0.22615	1	0.20267	1	0.67363	1	NA	NA	0.040711	0.571	0.72175	1	NA	NA	0.73994	1	NA	NA	NA	NA	0.64698	1	1	1
GUSB	4 (1%)	664	0.59336	1	0.057811	0.686	0.22257	1	0.33163	1	NA	NA	1	1	1	1	NA	NA	0.72134	1	NA	NA	NA	NA	1	1	1	1
MED16	4 (1%)	664	0.034978	0.519	0.82826	1	0.40982	1	0.32762	1	0.091339	0.9	1	1	0.60995	1	NA	NA	0.095849	0.9	NA	NA	NA	NA	1	1	1	1
PTCH1	8 (1%)	660	0.046376	0.602	0.29451	1	0.25858	1	0.077009	0.83	1	1	1	1	1	1	NA	NA	0.63017	1	NA	NA	NA	NA	0.64198	1	1	1
AHNAK2	33 (5%)	635	0.77312	1	0.23473	1	0.17128	1	0.11997	0.904	0.12243	0.904	0.56268	1	0.57377	1	0.8572	1	0.00161	0.0701	0.65443	1	0.14488	0.983	0.00455	0.131	0.65395	1
RLIM	9 (1%)	659	0.59534	1	0.12931	0.93	0.72951	1	0.76398	1	1	1	1	1	1	1	NA	NA	0.24936	1	NA	NA	NA	NA	0.67618	1	1	1
SLC23A1	7 (1%)	661	0.34218	1	0.30777	1	0.54171	1	1	1	0.3489	1	0.20625	1	0.23911	1	NA	NA	1	1	NA	NA	NA	NA	0.2691	1	1	1
STAM	6 (1%)	662	0.71429	1	0.43952	1	0.00049	0.0291	0.00168	0.0701	0.04698	0.602	0.099711	0.9	0.66972	1	NA	NA	0.074339	0.811	NA	NA	NA	NA	1	1	0.039031	0.57
RHEB	4 (1%)	664	0.83483	1	0.29684	1	0.8765	1	0.82662	1	NA	NA	0.37084	1	0.11904	0.904	NA	NA	1	1	NA	NA	NA	NA	0.403	1	1	1
SLC4A8	6 (1%)	662	0.4798	1	0.38246	1	0.55635	1	0.66527	1	NA	NA	1	1	0.66972	1	NA	NA	0.10334	0.9	NA	NA	NA	NA	1	1	1	1
RUFY3	7 (1%)	661	0.64742	1	0.56412	1	0.94671	1	0.88818	1	1	1	0.53875	1	0.4319	1	NA	NA	0.31151	1	NA	NA	NA	NA	0.59525	1	0.34467	1
PCK1	6 (1%)	662	0.1959	1	0.42636	1	0.26481	1	0.14827	0.986	1	1	0.60099	1	1	1	NA	NA	1	1	NA	NA	NA	NA	0.53546	1	1	1
TXNIP	8 (1%)	660	0.47199	1	0.60974	1	0.14295	0.983	0.29976	1	0.02012	0.352	0.32016	1	1	1	NA	NA	1	1	NA	NA	NA	NA	1	1	0.34467	1
RNF128	5 (1%)	663	0.59487	1	0.91252	1	0.46912	1	0.14288	0.983	NA	NA	1	1	0.66517	1	NA	NA	0.17102	1	NA	NA	NA	NA	0.17421	1	0.24507	1
ZFYVE26	9 (1%)	659	0.48529	1	0.26903	1	0.67847	1	0.69773	1	NA	NA	0.26314	1	1	1	NA	NA	0.87851	1	NA	NA	NA	NA	1	1	1	1
FAM160B2	4 (1%)	664	0.22292	1	0.74609	1	0.31279	1	0.65775	1	NA	NA	0.37084	1	0.60995	1	NA	NA	0.38402	1	NA	NA	NA	NA	1	1	1	1
FAM47A	6 (1%)	662	0.022987	0.376	0.34854	1	0.59927	1	0.56884	1	NA	NA	0.46122	1	0.019828	0.352	NA	NA	0.65451	1	NA	NA	NA	NA	1	1	1	1
ATP1A1	10 (1%)	658	0.23208	1	0.36545	1	0.29248	1	0.77878	1	NA	NA	0.092088	0.9	0.50707	1	NA	NA	0.46441	1	NA	NA	NA	NA	0.40605	1	1	1
SH3BP2	4 (1%)	664	0.53337	1	0.59514	1	1	1	0.65433	1	NA	NA	1	1	0.60995	1	NA	NA	0.095799	0.9	NA	NA	NA	NA	0.40402	1	1	1
FAM200A	5 (1%)	663	0.66984	1	0.60301	1	0.84011	1	0.60356	1	1	1	1	1	0.049471	0.626	NA	NA	0.46509	1	NA	NA	NA	NA	1	1	1	1
RTL1	7 (1%)	661	0.0082465	0.212	0.60905	1	0.01092	0.25	0.081109	0.855	1	1	0.15107	0.989	0.10213	0.9	NA	NA	0.15841	1	NA	NA	NA	NA	1	1	1	1
NASP	4 (1%)	664	0.10617	0.904	0.34251	1	0.22032	1	0.32991	1	NA	NA	1	1	0.11904	0.904	NA	NA	0.03473	0.519	NA	NA	NA	NA	1	1	0.24507	1
RPL7A	3 (0%)	665	0.75286	1	0.19983	1	0.59118	1	1	1	NA	NA	0.14286	0.983	0.55484	1	NA	NA	0.02266	0.376	NA	NA	NA	NA	0.31909	1	1	1
UIMC1	5 (1%)	663	0.0555	0.68	0.5318	1	0.29464	1	0.04477	0.598	1	1	0.53875	1	0.66517	1	NA	NA	1	1	NA	NA	NA	NA	1	1	1	1
TCEB1	3 (0%)	665	0.32505	1	0.1993	1	0.81452	1	0.43021	1	NA	NA	1	1	1	1	NA	NA	0.68289	1	NA	NA	NA	NA	0.3194	1	0.18991	1
SFMBT1	3 (0%)	665	0.11489	0.904	0.32228	1	1	1	1	1	NA	NA	1	1	0.27167	1	NA	NA	1	1	NA	NA	NA	NA	1	1	1	1
SLC16A1	3 (0%)	665	0.41585	1	0.19983	1	1	1	1	1	NA	NA	1	1	1	1	NA	NA	1	1	NA	NA	NA	NA	0.31887	1	0.18991	1
PAM	4 (1%)	664	0.22298	1	0.96147	1	0.77794	1	1	1	0.35121	1	1	1	1	1	NA	NA	0.094809	0.9	NA	NA	0.39907	1	0.32125	1	1	1
TMCO3	7 (1%)	661	0.523	1	0.56546	1	0.34013	1	0.62579	1	0.43928	1	1	1	0.23911	1	NA	NA	1	1	NA	NA	NA	NA	0.0315	0.482	0.29658	1
CCDC82	6 (1%)	662	0.35594	1	0.51417	1	0.87791	1	1	1	1	1	1	1	0.18838	1	NA	NA	0.25388	1	NA	NA	NA	NA	1	1	1	1
NFAT5	8 (1%)	660	0.77243	1	0.74375	1	0.34759	1	0.61223	1	1	1	0.60901	1	0.72175	1	NA	NA	0.74293	1	NA	NA	NA	NA	0.64303	1	1	1
HNF1B	3 (0%)	665	0.10916	0.904	0.76548	1	0.12283	0.904	0.18356	1	NA	NA	0.26553	1	0.27167	1	NA	NA	0.40045	1	NA	NA	NA	NA	NA	NA	1	1
OR2L8	7 (1%)	661	0.21424	1	0.5668	1	0.56824	1	0.49448	1	NA	NA	0.15107	0.989	0.23911	1	NA	NA	0.12411	0.906	NA	NA	NA	NA	1	1	1	1
IDUA	5 (1%)	663	0.69083	1	0.21325	1	0.84143	1	0.60687	1	NA	NA	1	1	0.66517	1	NA	NA	0.00184	0.071	NA	NA	NA	NA	0.17313	1	1	1
ZC3H18	6 (1%)	662	0.13687	0.969	0.77722	1	1	1	0.76336	1	NA	NA	1	1	0.41766	1	NA	NA	0.82108	1	NA	NA	NA	NA	0.53991	1	1	1
GAPDHS	5 (1%)	663	0.3071	1	0.39617	1	0.91878	1	0.60392	1	NA	NA	1	1	1	1	NA	NA	0.24811	1	NA	NA	NA	NA	0.17403	1	1	1
GPR137	4 (1%)	664	0.75592	1	0.38811	1	0.87741	1	0.82389	1	NA	NA	0.46122	1	1	1	NA	NA	1	1	NA	NA	NA	NA	1	1	1	1
GFM1	3 (0%)	665	0.70631	1	0.029487	0.474	0.68922	1	0.74168	1	NA	NA	0.26553	1	1	1	NA	NA	0.00081999	0.0458	NA	NA	NA	NA	1	1	1	1
FAT1	22 (3%)	646	0.5523	1	0.23055	1	0.26419	1	0.29414	1	0.29458	1	1	1	0.82252	1	NA	NA	0.00138	0.0669	0.8975	1	NA	NA	0.091729	0.9	0.62417	1
RRP12	9 (1%)	659	0.79196	1	0.11577	0.904	1	1	1	1	NA	NA	1	1	0.069623	0.777	NA	NA	0.57404	1	NA	NA	NA	NA	1	1	0.34467	1
