		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	87 (24%)	279	0.13108	0.402	0.12279	0.39	0.7975	0.93	0.97864	1	0.87216	0.969	0.35164	0.651	0.56747	0.779	0.92384	0.989	0.79941	0.93	0.49566	0.753
1q gain	171 (47%)	195	9.9999e-06	0.000586	0.66403	0.846	0.27064	0.578	0.5095	0.758	0.03354	0.186	0.33304	0.636	0.12483	0.392	0.31853	0.631	0.04777	0.23	0.286	0.595
2p gain	67 (18%)	299	0.01141	0.0926	0.26108	0.568	0.80136	0.931	0.81452	0.942	0.00403	0.0486	0.0077199	0.0749	0.10462	0.347	0.00012	0.00444	0.03901	0.204	0.02865	0.169
2q gain	65 (18%)	301	0.0079399	0.0749	0.45014	0.727	0.77694	0.918	0.34248	0.644	0.00050999	0.0113	0.01163	0.0926	0.1376	0.409	6.9999e-05	0.00302	0.052769	0.246	0.00212	0.0303
3p gain	63 (17%)	303	0.22029	0.519	0.25059	0.557	0.04451	0.225	0.01989	0.129	0.41748	0.699	0.33013	0.636	0.33144	0.636	0.55507	0.775	0.75494	0.909	0.97537	1
3q gain	72 (20%)	294	0.56421	0.778	0.4634	0.738	0.0184	0.122	0.046	0.228	0.04617	0.228	0.23929	0.541	0.13247	0.402	0.53252	0.762	0.20057	0.5	0.61703	0.815
4p gain	56 (15%)	310	0.00167	0.0258	0.18883	0.487	0.30481	0.617	0.85683	0.964	0.31459	0.628	0.24652	0.549	0.30488	0.617	0.04579	0.228	0.72962	0.896	0.56166	0.778
4q gain	47 (13%)	319	0.01153	0.0926	0.32084	0.632	0.26343	0.57	0.93433	0.989	0.2132	0.516	0.38653	0.675	0.68684	0.862	0.04208	0.214	0.77379	0.917	0.94212	0.989
5p gain	76 (21%)	290	0.00061999	0.0134	0.17238	0.463	0.88931	0.974	0.39706	0.684	0.22212	0.519	0.57995	0.786	0.087889	0.312	0.49811	0.753	0.98486	1	0.095809	0.329
5q gain	52 (14%)	314	0.0108	0.0904	0.13945	0.41	0.35747	0.651	0.13881	0.409	0.98184	1	0.77485	0.917	0.1049	0.347	0.52167	0.759	0.33017	0.636	0.073199	0.282
6p gain	144 (39%)	222	0.00043	0.0101	5.9999e-05	0.00273	0.98844	1	0.14383	0.42	0.32189	0.633	0.02466	0.152	0.00214	0.0303	0.056569	0.249	0.00028	0.00741	0.0018	0.0268
6q gain	48 (13%)	318	0.30821	0.619	0.58274	0.789	0.85611	0.964	0.3308	0.636	0.94262	0.989	0.68908	0.863	0.35421	0.651	0.40388	0.687	0.83368	0.955	0.64778	0.838
7p gain	203 (55%)	163	9.9999e-06	0.000586	0.93696	0.989	0.45873	0.736	0.37401	0.662	0.01894	0.124	0.19913	0.5	0.074929	0.282	0.74057	0.902	0.17331	0.463	0.57049	0.78
7q gain	200 (55%)	166	3e-05	0.00154	0.9116	0.984	0.69177	0.865	0.51493	0.758	0.0059299	0.0636	0.1899	0.487	0.68636	0.862	0.56966	0.78	0.0086499	0.0797	0.29996	0.612
8p gain	121 (33%)	245	9.9999e-06	0.000586	0.1775	0.473	0.61284	0.813	0.84357	0.957	0.01314	0.0995	0.03548	0.189	0.5241	0.76	0.84349	0.957	0.85172	0.964	0.43668	0.713
8q gain	169 (46%)	197	9.9999e-06	0.000586	0.00112	0.02	0.69444	0.865	0.79563	0.93	0.00411	0.0488	0.11198	0.364	0.63013	0.827	0.89152	0.974	0.80786	0.937	0.37573	0.662
9p gain	16 (4%)	350	0.3067	0.618	0.20408	0.504	0.37444	0.662	0.83542	0.955	0.34658	0.65	0.91159	0.984	0.90367	0.981	0.61039	0.811	0.12637	0.396	0.26611	0.574
9q gain	21 (6%)	345	0.65952	0.845	0.65698	0.845	0.13278	0.402	0.92928	0.989	0.56353	0.778	0.4931	0.753	0.88451	0.974	0.41515	0.698	0.47567	0.743	0.55557	0.775
10p gain	12 (3%)	354	0.49788	0.753	0.93049	0.989	0.86688	0.968	0.54548	0.77	0.71051	0.876	1	1	0.26246	0.569	0.55828	0.775	1	1	0.90474	0.981
10q gain	3 (1%)	363	0.378	0.662	0.3565	0.651	NA	NA	NA	NA	0.63612	0.832	0.63911	0.835	0.77804	0.918	0.72563	0.892	0.26863	0.577	0.68938	0.863
11p gain	35 (10%)	331	0.0060899	0.0636	0.094469	0.327	0.084599	0.304	0.18859	0.487	0.0013	0.0219	0.0077699	0.0749	0.02327	0.147	0.0062799	0.0636	0.23076	0.529	0.01744	0.118
11q gain	29 (8%)	337	2e-04	0.00607	0.18972	0.487	0.076379	0.285	0.084909	0.304	0.00306	0.0392	0.00131	0.0219	0.0059799	0.0636	0.00074999	0.0152	0.057439	0.25	0.01365	0.102
12p gain	65 (18%)	301	0.00077999	0.0152	0.16368	0.451	0.53958	0.768	0.4262	0.705	0.01231	0.0961	0.86371	0.967	0.87346	0.969	0.49252	0.753	0.16614	0.454	0.3696	0.662
12q gain	39 (11%)	327	0.01638	0.114	1	1	0.61636	0.815	0.057879	0.25	0.53913	0.768	0.64589	0.838	0.81703	0.944	0.061169	0.255	0.4226	0.7	0.68026	0.861
13q gain	94 (26%)	272	9.9999e-06	0.000586	9.9999e-06	0.000586	0.45936	0.736	0.31413	0.628	0.00047	0.0107	0.0062599	0.0636	0.49873	0.753	0.83896	0.957	0.090719	0.319	0.6848	0.862
14q gain	41 (11%)	325	0.39254	0.679	0.39888	0.684	0.34846	0.651	0.15425	0.44	0.83483	0.955	0.91532	0.985	0.51282	0.758	0.50804	0.758	0.7675	0.917	0.96731	1
15q gain	85 (23%)	281	5e-05	0.00241	0.19484	0.493	0.94469	0.989	0.81813	0.944	0.00372	0.0469	0.01612	0.113	0.19339	0.493	0.17264	0.463	0.3763	0.662	0.057309	0.25
16p gain	58 (16%)	308	0.00161	0.0254	0.03417	0.187	0.98798	1	0.65661	0.845	0.00036	0.00895	0.12321	0.39	0.78498	0.924	0.075109	0.282	0.069959	0.274	0.12321	0.39
16q gain	44 (12%)	322	0.00026	0.00711	0.053529	0.246	0.27474	0.581	0.62652	0.823	2e-05	0.00109	0.03323	0.186	0.78652	0.924	0.099299	0.336	0.054959	0.246	0.14672	0.425
17p gain	37 (10%)	329	0.0090799	0.0809	0.00102	0.0195	0.57888	0.786	0.53158	0.762	0.078449	0.287	0.51234	0.758	0.57151	0.78	0.29316	0.606	0.97453	1	0.13877	0.409
17q gain	65 (18%)	301	0.050679	0.237	0.04782	0.23	0.10282	0.344	0.27566	0.581	0.98492	1	0.3338	0.636	0.48023	0.747	0.67309	0.855	0.55615	0.775	0.7618	0.913
18p gain	55 (15%)	311	0.00255	0.0343	0.60584	0.808	0.20808	0.508	0.38971	0.677	0.25958	0.568	0.66391	0.846	0.93278	0.989	0.96583	1	0.060949	0.255	0.47268	0.741
18q gain	44 (12%)	322	0.00076999	0.0152	0.67714	0.858	0.35002	0.651	0.46989	0.74	0.21743	0.519	0.8302	0.953	0.67354	0.855	0.76362	0.914	0.64396	0.838	0.79689	0.93
19p gain	57 (16%)	309	0.0050799	0.0579	0.02362	0.148	0.25278	0.559	0.79786	0.93	0.00135	0.0221	0.24024	0.541	0.90571	0.981	0.54349	0.77	0.17239	0.463	0.90085	0.981
19q gain	56 (15%)	310	0.01062	0.0904	0.01782	0.12	0.29542	0.606	1	1	0.00012	0.00444	0.062179	0.255	0.5274	0.76	0.4317	0.712	0.15516	0.44	0.85471	0.964
20p gain	147 (40%)	219	9.9999e-06	0.000586	0.0089999	0.0809	0.84314	0.957	0.98406	1	0.00015	0.00492	0.02084	0.134	0.48713	0.753	0.27081	0.578	0.27315	0.579	0.065939	0.264
20q gain	179 (49%)	187	9.9999e-06	0.000586	0.0165	0.114	0.941	0.989	0.97401	1	0.00384	0.0477	0.16278	0.451	0.47859	0.746	0.26036	0.568	0.9147	0.985	0.28029	0.586
21q gain	67 (18%)	299	0.16422	0.451	0.04831	0.23	0.88842	0.974	0.52894	0.76	0.19435	0.493	0.35747	0.651	0.10906	0.356	0.99688	1	0.94933	0.993	0.51197	0.758
22q gain	126 (34%)	240	0.00038	0.00916	0.11836	0.381	0.89383	0.975	0.94453	0.989	0.073979	0.282	0.25204	0.559	0.61683	0.815	0.15903	0.447	0.69838	0.866	0.49559	0.753
xp gain	41 (11%)	325	0.00013	0.00444	0.00161	0.0254	0.9584	0.999	0.22797	0.527	0.0072799	0.0728	0.21999	0.519	0.66393	0.846	0.3984	0.684	0.00109	0.0199	0.40629	0.69
xq gain	43 (12%)	323	7.9999e-05	0.00328	0.00031	0.00794	0.58499	0.789	0.98573	1	0.00446	0.0522	0.18822	0.487	0.38709	0.675	0.27705	0.582	0.00023	0.00674	0.75611	0.909
1p loss	53 (14%)	313	0.04792	0.23	0.00026	0.00711	0.58701	0.79	0.31453	0.628	0.01072	0.0904	0.13425	0.402	0.0093299	0.0814	0.69345	0.865	0.17946	0.476	0.054379	0.246
1q loss	28 (8%)	338	0.066509	0.265	0.054849	0.246	0.96901	1	0.46584	0.739	0.1171	0.38	0.35434	0.651	0.36777	0.661	0.93833	0.989	0.2842	0.593	0.35714	0.651
2p loss	51 (14%)	315	0.37327	0.662	0.21157	0.514	0.04566	0.228	0.01493	0.107	0.92696	0.989	0.03531	0.189	0.00306	0.0392	0.065549	0.264	0.22439	0.521	0.21175	0.514
2q loss	52 (14%)	314	0.81472	0.942	0.19624	0.495	0.01106	0.091	0.0017	0.0258	0.75854	0.911	0.21434	0.517	0.0079299	0.0749	0.11803	0.381	0.16683	0.454	0.22305	0.52
3p loss	61 (17%)	305	0.059819	0.255	0.82026	0.945	0.49478	0.753	0.32596	0.636	0.10653	0.349	0.15573	0.44	0.060509	0.255	0.65959	0.845	0.52161	0.759	0.41118	0.692
3q loss	53 (14%)	313	0.04643	0.228	0.091019	0.319	0.50929	0.758	0.3721	0.662	0.37508	0.662	0.25387	0.56	0.12879	0.4	0.63334	0.83	0.32845	0.636	0.77052	0.917
4p loss	80 (22%)	286	0.52921	0.76	0.19988	0.5	0.35226	0.651	0.96938	1	0.16273	0.451	0.066069	0.264	0.54318	0.77	0.01323	0.0995	0.87921	0.971	0.31639	0.628
4q loss	85 (23%)	281	0.52938	0.76	0.070179	0.274	0.48113	0.747	0.75093	0.908	0.21747	0.519	0.03276	0.186	0.9025	0.981	0.0055899	0.0619	0.60489	0.808	0.24285	0.543
5p loss	79 (22%)	287	0.85255	0.964	0.1613	0.451	0.88085	0.971	0.86186	0.967	0.84226	0.957	0.076939	0.285	0.51233	0.758	0.25732	0.564	0.20765	0.508	0.3905	0.677
5q loss	99 (27%)	267	0.58757	0.79	0.055599	0.248	0.64766	0.838	0.35988	0.652	0.86176	0.967	0.050349	0.237	0.90801	0.982	0.57818	0.786	0.42055	0.7	0.60861	0.81
6p loss	68 (19%)	298	0.0050399	0.0579	0.46816	0.74	0.87284	0.969	0.27737	0.582	0.01263	0.0977	0.03518	0.189	0.0419	0.214	0.089479	0.316	0.02578	0.157	0.02755	0.164
6q loss	172 (47%)	194	9.9999e-06	0.000586	0.01425	0.105	0.97817	1	0.48231	0.748	0.00249	0.034	0.081369	0.297	0.22066	0.519	0.21853	0.519	0.40325	0.687	0.16223	0.451
7p loss	18 (5%)	348	0.82957	0.953	0.054179	0.246	0.094379	0.327	0.55731	0.775	0.42256	0.7	0.84245	0.957	0.64904	0.838	0.71017	0.876	0.16919	0.459	0.75153	0.908
7q loss	17 (5%)	349	0.35896	0.652	0.01051	0.0904	0.33736	0.637	0.4367	0.713	0.40407	0.687	0.41752	0.699	0.52071	0.759	0.77167	0.917	0.096189	0.329	0.92756	0.989
8p loss	67 (18%)	299	0.1225	0.39	0.45145	0.727	0.058709	0.252	0.29581	0.606	0.057759	0.25	0.5245	0.76	0.46224	0.737	0.02933	0.172	0.43597	0.713	0.18055	0.476
8q loss	27 (7%)	339	0.51973	0.759	0.0079499	0.0749	0.31638	0.628	0.53499	0.764	0.2309	0.529	0.73822	0.902	0.40892	0.692	0.5041	0.757	0.01474	0.107	0.14551	0.423
9p loss	236 (64%)	130	0.00013	0.00444	0.13341	0.402	0.6444	0.838	0.45052	0.727	0.00275	0.0364	0.10118	0.34	0.075309	0.282	0.22086	0.519	0.73885	0.902	0.59081	0.793
9q loss	185 (51%)	181	0.27238	0.579	0.070859	0.275	0.9923	1	0.14935	0.43	0.01223	0.0961	0.33355	0.636	0.03977	0.205	0.13773	0.409	0.96939	1	0.46619	0.739
10p loss	204 (56%)	162	9.9999e-06	0.000586	0.12861	0.4	0.92387	0.989	0.4106	0.692	0.00117	0.0204	0.01614	0.113	0.060829	0.255	0.35014	0.651	0.37215	0.662	0.5642	0.778
10q loss	224 (61%)	142	9.9999e-06	0.000586	0.20789	0.508	0.9206	0.989	0.20175	0.501	0.00019	0.00599	0.00239	0.0332	0.02093	0.134	0.36258	0.653	0.32976	0.636	0.50078	0.753
11p loss	126 (34%)	240	0.01795	0.12	0.055929	0.248	0.5842	0.789	0.29447	0.606	0.46897	0.74	0.098029	0.334	0.52201	0.759	0.33542	0.637	0.083409	0.301	0.56853	0.78
11q loss	148 (40%)	218	0.01303	0.0995	0.34955	0.651	0.95247	0.994	0.69592	0.866	0.22161	0.519	0.00195	0.0286	0.73631	0.901	0.15834	0.446	0.075159	0.282	0.54976	0.775
12p loss	59 (16%)	307	0.21981	0.519	0.10613	0.349	0.85709	0.964	0.87169	0.969	0.01443	0.106	0.89242	0.974	0.12472	0.392	0.43535	0.713	0.98135	1	0.57742	0.786
12q loss	67 (18%)	299	0.03335	0.186	0.0080599	0.0751	0.98322	1	0.8758	0.97	0.050329	0.237	0.55748	0.775	0.133	0.402	0.50073	0.753	0.45052	0.727	0.69824	0.866
13q loss	80 (22%)	286	0.93522	0.989	0.0111	0.091	0.065589	0.264	0.55706	0.775	0.66123	0.846	0.03423	0.187	0.79686	0.93	0.20287	0.503	0.3226	0.633	0.47166	0.741
14q loss	112 (31%)	254	9.9999e-06	0.000586	0.32042	0.632	0.40977	0.692	0.27149	0.578	0.0090699	0.0809	0.0331	0.186	0.0057099	0.0624	0.21631	0.519	0.33437	0.636	0.23636	0.535
15q loss	52 (14%)	314	0.18245	0.478	0.35605	0.651	0.28884	0.598	0.061769	0.255	0.79891	0.93	0.26704	0.575	0.64663	0.838	0.42121	0.7	0.28825	0.598	0.46058	0.736
16p loss	68 (19%)	298	0.20474	0.504	0.094899	0.327	0.063959	0.261	0.35993	0.652	0.061369	0.255	0.15519	0.44	0.23514	0.535	0.19359	0.493	0.1339	0.402	0.30576	0.618
16q loss	106 (29%)	260	0.3019	0.614	0.32529	0.636	0.01544	0.11	0.75463	0.909	0.03724	0.196	0.03573	0.189	0.32821	0.636	0.10443	0.347	0.068159	0.27	0.18242	0.478
17p loss	127 (35%)	239	0.078449	0.287	0.0055099	0.0619	0.44416	0.722	0.51483	0.758	0.18666	0.487	0.053219	0.246	0.88	0.971	0.51931	0.759	0.62433	0.822	0.44197	0.721
17q loss	64 (17%)	302	0.14179	0.415	0.13343	0.402	0.13089	0.402	0.54112	0.769	0.92548	0.989	0.49457	0.753	0.50864	0.758	0.87	0.969	0.062289	0.255	1	1
18p loss	104 (28%)	262	0.73162	0.897	0.60098	0.804	0.37713	0.662	0.51013	0.758	0.02606	0.157	0.16433	0.451	0.02746	0.164	0.39007	0.677	0.54535	0.77	0.15201	0.436
18q loss	100 (27%)	266	0.45186	0.727	0.88036	0.971	0.29811	0.61	0.49019	0.753	0.44454	0.722	0.43523	0.713	0.75012	0.908	0.23026	0.529	0.55848	0.775	0.17324	0.463
19p loss	77 (21%)	289	0.074899	0.282	0.65826	0.845	0.78328	0.923	0.03347	0.186	0.14722	0.425	0.25584	0.562	0.56673	0.779	0.8867	0.974	0.23633	0.535	0.51609	0.758
19q loss	73 (20%)	293	0.02494	0.153	0.04721	0.23	0.9774	1	0.082209	0.298	0.091819	0.32	0.49431	0.753	0.48751	0.753	0.98865	1	0.053929	0.246	0.52727	0.76
20p loss	26 (7%)	340	0.37143	0.662	0.62045	0.818	0.23611	0.535	0.77247	0.917	0.19955	0.5	0.02156	0.137	0.13408	0.402	0.01672	0.114	0.89087	0.974	0.18785	0.487
20q loss	9 (2%)	357	0.39758	0.684	0.17983	0.476	NA	NA	NA	NA	0.073799	0.282	0.0092999	0.0814	0.68509	0.862	0.55573	0.775	0.36204	0.653	0.68257	0.862
21q loss	70 (19%)	296	0.10058	0.339	0.47455	0.743	0.46946	0.74	0.93194	0.989	0.93004	0.989	0.49356	0.753	0.33675	0.637	0.74704	0.908	0.59532	0.798	0.76808	0.917
22q loss	39 (11%)	327	0.40298	0.687	0.42115	0.7	0.9531	0.994	0.94002	0.989	0.24139	0.541	0.96342	1	0.8644	0.967	0.69875	0.866	0.70745	0.875	0.7733	0.917
xp loss	97 (27%)	269	0.03068	0.178	9.9999e-06	0.000586	0.086549	0.309	0.22558	0.523	0.00109	0.0199	0.00396	0.0485	0.02471	0.152	0.33922	0.639	0.03091	0.178	0.75166	0.908
xq loss	93 (25%)	273	0.03952	0.205	9.9999e-06	0.000586	0.24092	0.541	0.078429	0.287	0.00069999	0.0147	0.0062499	0.0636	0.069829	0.274	0.71722	0.883	0.03534	0.189	0.74959	0.908
