		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	24 (43%)	32	0.20237	0.773	0.75418	0.998	0.76738	0.998	0.69481	0.998	0.81997	1	0.90016	1	0.52697	0.965	0.28061	0.808	0.60762	0.974	0.56737	0.971
1q gain	31 (55%)	25	0.43921	0.928	0.76812	0.998	0.77384	0.998	0.58924	0.971	0.76102	0.998	0.61815	0.976	0.70623	0.998	0.45586	0.94	0.88359	1	0.81294	1
2p gain	23 (41%)	33	0.88839	1	0.0073499	0.405	1	1	0.03453	0.618	0.01949	0.513	0.055469	0.637	0.49432	0.958	0.072419	0.68	0.10233	0.729	0.13539	0.74
2q gain	21 (38%)	35	0.37028	0.875	0.01911	0.513	0.55064	0.971	0.31641	0.825	0.01221	0.472	0.1129	0.729	0.62205	0.976	0.04929	0.618	0.1952	0.773	0.11146	0.729
3p gain	12 (21%)	44	0.21122	0.773	0.2612	0.805	0.0864	0.705	0.20972	0.773	0.43278	0.926	0.19963	0.773	0.86131	1	0.26392	0.808	0.45205	0.94	0.55219	0.971
3q gain	23 (41%)	33	0.10056	0.729	0.04794	0.618	0.14938	0.753	0.56481	0.971	0.1969	0.773	0.11997	0.729	0.49137	0.958	0.18944	0.773	0.074579	0.68	0.21918	0.773
4p gain	9 (16%)	47	0.73201	0.998	0.70046	0.998	0.21677	0.773	0.02712	0.573	0.82337	1	0.86692	1	0.77588	0.998	0.32643	0.843	0.2612	0.805	0.36902	0.875
4q gain	3 (5%)	53	1	1	0.25729	0.805	1	1	NA	NA	0.51394	0.965	0.7935	1	0.67267	0.998	0.56452	0.971	0.59982	0.971	0.6946	0.998
5p gain	23 (41%)	33	0.04581	0.618	0.37666	0.875	0.015683	0.513	0.19836	0.773	0.4539	0.94	0.24457	0.788	0.74193	0.998	0.0277	0.573	0.60173	0.971	0.14772	0.753
5q gain	8 (14%)	48	0.50781	0.965	0.56463	0.971	0.15759	0.759	0.20757	0.773	0.3093	0.817	0.24877	0.792	0.080179	0.68	0.15267	0.753	0.12954	0.736	0.1929	0.773
6p gain	30 (54%)	26	0.19607	0.773	0.52367	0.965	0.77036	0.998	0.52526	0.965	0.60115	0.971	0.41309	0.922	1	1	0.47577	0.944	0.73458	0.998	0.3227	0.837
6q gain	27 (48%)	29	0.20925	0.773	0.20769	0.773	1	1	0.619	0.976	0.22304	0.773	0.16499	0.773	1	1	0.18895	0.773	0.65024	0.994	0.1377	0.74
7p gain	21 (38%)	35	0.19761	0.773	0.55428	0.971	0.22227	0.773	0.29451	0.808	0.15225	0.753	0.28166	0.808	0.58845	0.971	0.12942	0.736	0.32974	0.843	0.12066	0.729
7q gain	17 (30%)	39	0.58696	0.971	0.84098	1	0.52028	0.965	0.87092	1	0.34225	0.861	0.80906	1	0.74515	0.998	0.16561	0.773	1	1	0.15433	0.753
8p gain	19 (34%)	37	0.18781	0.773	0.74441	0.998	0.75831	0.998	0.28012	0.808	0.44388	0.935	0.87342	1	0.97038	1	0.55795	0.971	0.66154	0.998	0.59583	0.971
8q gain	30 (54%)	26	0.01458	0.501	0.19838	0.773	0.77248	0.998	0.59314	0.971	0.04874	0.618	0.50524	0.964	0.21761	0.773	0.32867	0.843	0.065699	0.668	0.12232	0.729
9p gain	6 (11%)	50	0.34906	0.863	0.70286	0.998	0.31124	0.817	0.12214	0.729	0.93576	1	0.66409	0.998	0.83193	1	0.80307	1	0.86193	1	1	1
10p gain	21 (38%)	35	0.33119	0.844	0.02052	0.513	0.04341	0.618	0.29946	0.808	0.04026	0.618	0.1203	0.729	0.32322	0.837	0.1053	0.729	0.67556	0.998	0.20034	0.773
10q gain	17 (30%)	39	0.8722	1	0.33743	0.854	0.12187	0.729	0.46437	0.944	0.55546	0.971	0.04629	0.618	0.22281	0.773	0.18451	0.773	0.38267	0.875	0.071889	0.68
11p gain	5 (9%)	51	0.72179	0.998	0.44538	0.936	0.64405	0.993	0.92406	1	0.2679	0.808	0.85136	1	0.49032	0.958	0.11648	0.729	0.51838	0.965	0.092299	0.708
11q gain	7 (12%)	49	0.68434	0.998	0.38735	0.879	0.68384	0.998	0.71689	0.998	0.22596	0.773	0.3822	0.875	0.75275	0.998	0.03479	0.618	0.57964	0.971	0.02939	0.576
12p gain	22 (39%)	34	0.26172	0.805	0.00415	0.376	0.37416	0.875	0.59503	0.971	0.37402	0.875	0.04181	0.618	0.8101	1	0.97717	1	0.53243	0.965	0.62723	0.976
12q gain	11 (20%)	45	0.53994	0.971	0.5328	0.965	0.47539	0.944	0.85584	1	0.80324	1	0.52279	0.965	1	1	0.29735	0.808	0.91188	1	0.26823	0.808
13q gain	15 (27%)	41	0.64882	0.993	0.070399	0.68	0.099861	0.729	0.54234	0.971	0.02218	0.515	0.02451	0.553	0.22507	0.773	0.04654	0.618	0.01001	0.434	0.14168	0.746
14q gain	7 (12%)	49	0.6089	0.974	0.57698	0.971	0.11737	0.729	0.04891	0.618	0.25658	0.805	0.26059	0.805	0.20689	0.773	0.73292	0.998	0.22567	0.773	0.47673	0.944
15q gain	4 (7%)	52	0.18803	0.773	0.25726	0.805	0.31124	0.817	0.58143	0.971	0.57628	0.971	0.32853	0.843	0.75609	0.998	0.34952	0.863	0.4219	0.923	0.35549	0.864
16p gain	10 (18%)	46	0.10848	0.729	0.27901	0.808	1	1	0.82745	1	0.19489	0.773	0.2772	0.808	1	1	0.4835	0.948	0.90337	1	0.40744	0.912
16q gain	6 (11%)	50	0.17047	0.773	0.84684	1	1	1	0.92405	1	0.54392	0.971	0.96915	1	0.77112	0.998	0.92501	1	0.47921	0.944	0.86798	1
17p gain	9 (16%)	47	0.38564	0.878	0.89601	1	0.43724	0.926	0.8268	1	0.56726	0.971	0.55881	0.971	0.2832	0.808	0.060589	0.668	0.12775	0.736	0.17328	0.773
17q gain	18 (32%)	38	0.42184	0.923	0.27046	0.808	0.75831	0.998	0.80063	1	0.69848	0.998	0.51422	0.965	0.39182	0.887	0.30273	0.808	0.76014	0.998	0.43021	0.926
18p gain	18 (32%)	38	0.67959	0.998	0.04906	0.618	0.35463	0.864	0.78533	1	0.093319	0.709	0.34461	0.862	0.14543	0.753	0.20226	0.773	0.40656	0.912	0.43275	0.926
18q gain	14 (25%)	42	0.68526	0.998	0.080839	0.68	0.47539	0.944	0.59212	0.971	0.15319	0.753	0.24181	0.788	0.20306	0.773	0.087979	0.705	0.14021	0.743	0.16901	0.773
19p gain	24 (43%)	32	0.11581	0.729	0.18089	0.773	1	1	0.72615	0.998	0.27135	0.808	0.36946	0.875	0.53524	0.968	0.22807	0.774	0.41624	0.923	0.51754	0.965
19q gain	28 (50%)	28	0.12371	0.729	0.076629	0.68	1	1	0.87407	1	0.37638	0.875	0.39616	0.894	0.92968	1	0.89857	1	0.88428	1	0.93705	1
20p gain	37 (66%)	19	0.28745	0.808	0.50267	0.964	1	1	0.59711	0.971	0.9225	1	0.76044	0.998	0.87384	1	0.69765	0.998	0.22131	0.773	0.4673	0.944
20q gain	44 (79%)	12	0.051549	0.636	0.91919	1	1	1	0.95264	1	0.96887	1	0.99697	1	0.59025	0.971	0.57411	0.971	0.215	0.773	0.67984	0.998
21q gain	18 (32%)	38	0.071939	0.68	0.37928	0.875	0.75831	0.998	0.78676	1	0.90158	1	0.89194	1	0.91517	1	0.57224	0.971	1	1	0.94759	1
22q gain	8 (14%)	48	0.71141	0.998	0.95965	1	0.31124	0.817	0.3022	0.808	0.80421	1	0.92575	1	0.88704	1	0.94429	1	1	1	1	1
xp gain	18 (32%)	38	0.93792	1	0.01008	0.434	0.53272	0.965	0.47927	0.944	0.01927	0.513	0.24548	0.788	0.7981	1	0.55987	0.971	0.20189	0.773	0.43301	0.926
xq gain	15 (27%)	41	0.69508	0.998	0.36236	0.867	0.34187	0.861	0.76432	0.998	0.76389	0.998	0.71624	0.998	0.86926	1	0.29198	0.808	1	1	0.089829	0.705
1p loss	9 (16%)	47	0.594	0.971	0.6031	0.971	0.43724	0.926	0.62774	0.976	0.92081	1	0.11917	0.729	0.11021	0.729	0.02987	0.576	0.055529	0.637	0.04679	0.618
1q loss	9 (16%)	47	0.48272	0.948	0.51768	0.965	0.43724	0.926	0.29971	0.808	0.5149	0.965	0.078739	0.68	0.42198	0.923	0.15337	0.753	0.21012	0.773	0.14395	0.753
3p loss	20 (36%)	36	0.01045	0.434	0.42318	0.923	1	1	0.71239	0.998	0.04856	0.618	0.22815	0.774	0.37618	0.875	0.92868	1	0.4213	0.923	0.43026	0.926
3q loss	14 (25%)	42	0.13862	0.74	0.4614	0.944	0.74382	0.998	0.79529	1	0.13699	0.74	0.60392	0.971	0.52575	0.965	0.87942	1	0.38194	0.875	1	1
4p loss	31 (55%)	25	0.064839	0.668	0.063959	0.668	1	1	0.080929	0.68	0.25671	0.805	0.2026	0.773	0.03719	0.618	0.71451	0.998	0.14819	0.753	0.4482	0.938
4q loss	33 (59%)	23	0.19042	0.773	0.01847	0.513	0.23155	0.778	0.090129	0.705	0.00461	0.376	0.03938	0.618	0.00018	0.142	0.24793	0.792	0.02035	0.513	0.13569	0.74
5p loss	9 (16%)	47	0.9028	1	0.4768	0.944	0.0056153	0.376	0.060889	0.668	0.88541	1	0.13599	0.74	1	1	0.29759	0.808	1	1	0.41812	0.923
5q loss	18 (32%)	38	0.77071	0.998	0.30669	0.816	0.54682	0.971	0.078459	0.68	0.26697	0.808	0.23379	0.783	0.36199	0.867	0.94598	1	0.35636	0.864	0.947	1
6p loss	5 (9%)	51	0.42422	0.923	0.95515	1	0.57909	0.971	0.74913	0.998	0.75453	0.998	0.95664	1	0.54318	0.971	0.90923	1	1	1	1	1
6q loss	7 (12%)	49	0.063999	0.668	0.69958	0.998	0.64405	0.993	0.16653	0.773	0.63907	0.99	0.90015	1	0.70593	0.998	0.6187	0.976	0.67256	0.998	0.61449	0.976
7p loss	13 (23%)	43	1	1	0.66611	0.998	1	1	0.28662	0.808	0.7348	0.998	0.49984	0.961	0.31408	0.822	0.45487	0.94	0.77504	0.998	0.59783	0.971
7q loss	13 (23%)	43	0.12062	0.729	0.85412	1	0.73389	0.998	0.49548	0.958	0.9195	1	0.82209	1	0.71391	0.998	0.22085	0.773	1	1	0.52867	0.965
8p loss	23 (41%)	33	0.28494	0.808	0.98107	1	0.77454	0.998	0.27245	0.808	0.82607	1	0.74518	0.998	0.68907	0.998	0.51432	0.965	0.60463	0.971	0.57928	0.971
8q loss	9 (16%)	47	1	1	0.75707	0.998	0.43642	0.926	0.68906	0.998	0.29437	0.808	0.71457	0.998	0.94984	1	0.75719	0.998	0.26173	0.805	0.67051	0.998
9p loss	34 (61%)	22	0.29764	0.808	0.0078199	0.405	1	1	0.00048	0.19	0.6752	0.998	0.13592	0.74	0.86169	1	0.28886	0.808	1	1	0.059289	0.668
9q loss	39 (70%)	17	0.18938	0.773	0.00147	0.29	1	1	0.02127	0.513	0.49623	0.958	0.03811	0.618	0.66363	0.998	0.11736	0.729	1	1	0.16096	0.771
10p loss	23 (41%)	33	0.62448	0.976	0.01344	0.483	0.24513	0.788	0.72115	0.998	0.02827	0.573	0.18516	0.773	0.24314	0.788	0.78962	1	0.88041	1	0.89392	1
10q loss	21 (38%)	35	0.88585	1	0.30034	0.808	0.13763	0.74	0.78066	1	0.17576	0.773	0.17097	0.773	0.12338	0.729	0.47259	0.944	0.39767	0.895	0.73708	0.998
11p loss	26 (46%)	30	1	1	0.00402	0.376	0.77384	0.998	0.85547	1	0.37813	0.875	0.51615	0.965	0.26912	0.808	0.57988	0.971	0.51018	0.965	0.36159	0.867
11q loss	24 (43%)	32	0.62595	0.976	0.0081999	0.405	0.77454	0.998	0.80555	1	0.80353	1	0.8945	1	0.29393	0.808	0.58819	0.971	0.22511	0.773	0.18471	0.773
12p loss	13 (23%)	43	0.30224	0.808	0.27495	0.808	0.18074	0.773	0.74114	0.998	0.57862	0.971	0.7343	0.998	0.55002	0.971	0.57988	0.971	1	1	0.21959	0.773
12q loss	14 (25%)	42	0.42787	0.926	0.8812	1	0.50498	0.964	0.12542	0.734	0.8201	1	0.91516	1	0.96427	1	0.90718	1	0.92096	1	0.60283	0.971
13q loss	26 (46%)	30	0.41611	0.923	0.00114	0.29	0.23885	0.786	0.14847	0.753	0.055669	0.637	0.0279	0.573	0.35394	0.864	0.12073	0.729	0.03932	0.618	0.1955	0.773
14q loss	27 (48%)	29	0.94338	1	0.090559	0.705	0.56121	0.971	0.11762	0.729	0.12171	0.729	0.12284	0.729	0.61681	0.976	0.89796	1	0.93892	1	0.93624	1
15q loss	32 (57%)	24	0.0061899	0.376	0.71253	0.998	0.77248	0.998	0.053409	0.637	0.92868	1	0.98056	1	0.93022	1	0.97833	1	1	1	0.89483	1
16p loss	32 (57%)	24	0.2439	0.788	0.49411	0.958	1	1	0.088079	0.705	0.34682	0.862	0.099849	0.729	0.81147	1	0.9131	1	0.47098	0.944	0.89657	1
16q loss	37 (66%)	19	0.77721	0.998	0.79373	1	1	1	0.12895	0.736	0.45248	0.94	0.091039	0.705	0.68592	0.998	0.92304	1	0.13867	0.74	0.85701	1
17p loss	34 (61%)	22	0.54797	0.971	0.28518	0.808	0.04341	0.618	0.27301	0.808	0.97999	1	0.75848	0.998	0.80511	1	0.89141	1	0.23771	0.786	0.88735	1
17q loss	17 (30%)	39	0.16232	0.772	0.35787	0.865	0.52798	0.965	0.62741	0.976	0.71479	0.998	0.38331	0.875	0.96864	1	0.21162	0.773	0.93028	1	0.27752	0.808
18p loss	18 (32%)	38	0.03177	0.598	0.01658	0.513	0.35508	0.864	0.28606	0.808	0.054689	0.637	0.090329	0.705	0.066869	0.669	0.079199	0.68	0.061729	0.668	0.04711	0.618
18q loss	20 (36%)	36	0.11639	0.729	0.071319	0.68	0.36575	0.873	0.29534	0.808	0.18488	0.773	0.11933	0.729	0.01256	0.472	0.0057099	0.376	0.0059999	0.376	0.00231	0.365
19p loss	15 (27%)	41	0.56308	0.971	0.46525	0.944	0.30004	0.808	0.47129	0.944	0.20321	0.773	0.35666	0.864	0.34582	0.862	0.71577	0.998	0.21181	0.773	0.70439	0.998
19q loss	13 (23%)	43	0.73263	0.998	0.15217	0.753	0.47539	0.944	0.81844	1	0.9444	1	0.61625	0.976	0.22978	0.776	0.87467	1	0.23502	0.783	1	1
20p loss	7 (12%)	49	0.5371	0.969	0.20754	0.773	1	1	0.00315	0.376	0.080849	0.68	0.073729	0.68	0.61809	0.976	0.69291	0.998	0.57743	0.971	0.6915	0.998
20q loss	4 (7%)	52	0.37211	0.875	0.60228	0.971	0.57909	0.971	0.19154	0.773	0.11774	0.729	0.4752	0.944	1	1	0.88588	1	0.66602	0.998	0.78893	1
21q loss	17 (30%)	39	0.67073	0.998	0.18155	0.773	1	1	0.33314	0.846	0.63048	0.979	0.74673	0.998	0.68244	0.998	0.97165	1	0.93173	1	0.94213	1
22q loss	33 (59%)	23	0.17801	0.773	0.97068	1	0.065932	0.668	0.02144	0.513	0.96329	1	0.90225	1	0.71058	0.998	0.29009	0.808	0.46883	0.944	0.75831	0.998
xp loss	15 (27%)	41	0.64868	0.993	0.83695	1	0.75186	0.998	0.34464	0.862	0.9275	1	0.92785	1	0.44897	0.938	0.64634	0.993	0.49998	0.961	0.75996	0.998
xq loss	18 (32%)	38	0.76782	0.998	0.15757	0.759	0.75831	0.998	0.21606	0.773	0.23665	0.786	0.62086	0.976	0.45746	0.941	0.6456	0.993	0.53138	0.965	0.70871	0.998
