Clinical Features Time to Death YEARS_TO_BIRTH NEOPLASM_DISEASESTAGE PATHOLOGY_T_STAGE PATHOLOGY_N_STAGE GENDER ETHNICITY nMutated (%) nWild-Type logrank test_P logrank test_Q Wilcoxon-test_P Wilcoxon-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q ZFPM1 24 (39%) 38 0.20187 1 0.53413 1 0.31857 1 0.97424 1 0.66624 1 1 1 0.67692 1 LACTB 19 (31%) 43 0.78229 1 0.94519 1 0.19392 1 0.10788 1 1 1 0.56782 1 0.65598 1 CCDC102A 17 (27%) 45 0.17444 1 0.47745 1 0.14588 1 0.20775 1 0.17026 1 1 1 1 1 ZNF517 13 (21%) 49 0.99234 1 0.042075 0.956 0.73585 1 0.75038 1 1 1 0.75624 1 0.30578 1 MAL2 11 (18%) 51 0.75336 1 0.070821 1 0.45163 1 0.0453 0.956 0.3017 1 0.078935 1 0.29969 1 CLDN23 10 (16%) 52 0.93425 1 0.716 1 0.62283 1 0.75464 1 0.25938 1 0.47182 1 0.5585 1 TOR3A 12 (19%) 50 0.56822 1 0.53269 1 0.18685 1 0.13738 1 0.58102 1 0.73958 1 1 1 USP42 15 (24%) 47 0.74989 1 0.68098 1 0.52805 1 0.79053 1 0.63394 1 0.54086 1 1 1 TP53 12 (19%) 50 0.041514 0.956 0.78232 1 0.095759 1 0.26554 1 1 1 0.73958 1 0.57981 1 APOE 7 (11%) 55 0.87917 1 0.13307 1 1 1 0.91945 1 1 1 0.086091 1 1 1 ZAR1 11 (18%) 51 0.2302 1 0.67156 1 0.65455 1 0.33026 1 0.3017 1 0.078935 1 0.5585 1 ASPDH 8 (13%) 54 0.33344 1 0.98324 1 0.00299 0.83 0.30952 1 0.1051 1 0.70029 1 1 1 KCNK17 9 (15%) 53 0.28085 1 0.71895 1 0.8516 1 0.42874 1 0.5847 1 0.70862 1 0.18007 1 LZTR1 6 (10%) 56 0.47961 1 0.46025 1 1 1 1 1 0.48412 1 1 1 1 1 ERCC2 10 (16%) 52 0.84114 1 0.83318 1 0.60126 1 0.63574 1 0.25938 1 1 1 0.5112 1 RINL 8 (13%) 54 0.35946 1 0.62153 1 0.61652 1 0.51504 1 1 1 0.70029 1 0.26837 1 SYT8 8 (13%) 54 0.14258 1 0.40665 1 0.22978 1 0.69314 1 0.5847 1 1 1 0.5585 1 LRIG1 16 (26%) 46 0.79185 1 0.45908 1 0.91307 1 0.74544 1 0.15876 1 0.37529 1 0.64446 1 C1ORF106 9 (15%) 53 0.14803 1 0.38448 1 0.51514 1 0.30648 1 0.21798 1 0.14043 1 0.5585 1 GPRIN2 8 (13%) 54 0.56672 1 0.40073 1 0.94358 1 0.57998 1 0.5847 1 1 1 1 1 CTNNB1 7 (11%) 55 0.28466 1 0.26585 1 0.68361 1 0.93417 1 0.14019 1 0.044325 0.956 0.5585 1 C16ORF3 5 (8%) 57 0.43392 1 0.75628 1 0.23833 1 0.56068 1 0.42095 1 0.15097 1 1 1 CCDC105 6 (10%) 56 0.44415 1 0.43182 1 0.28113 1 0.10298 1 0.48412 1 0.080787 1 0.5112 1 RGS9BP 8 (13%) 54 0.43912 1 0.98324 1 0.93772 1 0.03475 0.956 0.54144 1 0.43805 1 0.5112 1 HHIPL1 6 (10%) 56 0.77937 1 0.60024 1 0.73005 1 0.63889 1 0.48412 1 0.65659 1 1 1 C10ORF95 6 (10%) 56 0.94649 1 0.53569 1 0.35832 1 0.7068 1 1 1 1 1 1 1 TSC22D2 8 (13%) 54 0.025218 0.956 0.62897 1 0.27525 1 0.11222 1 1 1 0.70029 1 0.5112 1 NOXA1 5 (8%) 57 0.65522 1 0.98968 1 0.89694 1 0.79708 1 0.42095 1 0.15097 1 1 1 THEM4 5 (8%) 57 0.42591 1 0.31312 1 0.4791 1 0.38714 1 0.35146 1 0.64731 1 1 1 ATXN1 10 (16%) 52 0.71734 1 0.26265 1 0.74934 1 0.43257 1 1 1 0.082016 1 1 1 PLIN5 5 (8%) 57 0.40487 1 0.58703 1 1 1 0.89376 1 0.42095 1 0.64731 1 0.37433 1 OPRD1 12 (19%) 50 0.92649 1 0.139 1 1 1 1 1 1 1 0.5123 1 1 1 KRTAP4-5 5 (8%) 57 0.13389 1 0.47692 1 0.57255 1 0.31129 1 1 1 0.64731 1 1 1 C19ORF10 7 (11%) 55 0.93249 1 0.53323 1 0.14363 1 0.47581 1 0.54144 1 0.40475 1 1 1 AATK 6 (10%) 56 0.33612 1 0.034003 0.956 0.68091 1 0.70908 1 0.48412 1 0.40908 1 1 1 SARM1 6 (10%) 56 0.22352 1 0.73877 1 0.63193 1 0.23403 1 1 1 0.65659 1 0.1006 1 TRIOBP 10 (16%) 52 0.79646 1 0.76662 1 0.95327 1 1 1 0.052374 0.981 0.082016 1 1 1 ZNF598 12 (19%) 50 0.3447 1 0.020975 0.956 0.51276 1 0.86637 1 0.58102 1 0.018637 0.956 0.57981 1 WDR34 5 (8%) 57 0.53946 1 0.679 1 1 1 0.73535 1 1 1 0.049287 0.956 1 1 ZNF628 7 (11%) 55 0.028072 0.956 0.75539 1 0.43429 1 0.41453 1 1 1 1 1 0.5112 1 BTBD11 6 (10%) 56 0.70656 1 0.86757 1 0.03695 0.956 0.14338 1 0.48412 1 0.40908 1 1 1 IRX3 5 (8%) 57 0.90562 1 0.31312 1 0.23575 1 0.50507 1 1 1 0.64731 1 1 1 FPGS 5 (8%) 57 0.1125 1 0.31936 1 0.23713 1 0.56036 1 0.42095 1 1 1 1 1 MEN1 5 (8%) 57 0.077224 1 0.6885 1 0.03318 0.956 0.15316 1 0.35146 1 1 1 0.5112 1 BHLHE22 5 (8%) 57 0.19818 1 0.92787 1 0.28738 1 0.89511 1 0.073514 1 0.64731 1 0.18007 1 DMKN 3 (5%) 59 0.19925 1 0.38445 1 NA NA NA NA 1 1 1 1 1 1 OBSCN 18 (29%) 44 0.79687 1 0.045341 0.956 0.43565 1 0.83806 1 0.33789 1 0.56134 1 1 1 PANK2 5 (8%) 57 0.007328 0.858 0.16644 1 0.89676 1 0.6214 1 1 1 0.049287 0.956 1 1 RREB1 5 (8%) 57 0.8242 1 0.93815 1 0.63405 1 0.23515 1 0.073514 1 1 1 0.37433 1 RNF149 4 (6%) 58 0.18902 1 0.070917 1 0.23012 1 0.38715 1 1 1 1 1 1 1 GLTPD2 6 (10%) 56 0.38938 1 0.10025 1 0.6336 1 0.61888 1 1 1 0.65659 1 0.20588 1 SNED1 5 (8%) 57 0.35328 1 0.73669 1 0.12926 1 0.16166 1 0.073514 1 0.64731 1 1 1 TPO 12 (19%) 50 0.76375 1 0.85153 1 0.86518 1 0.9519 1 0.087936 1 1 1 1 1 PTPLA 4 (6%) 58 0.68132 1 0.72009 1 0.60683 1 0.64073 1 1 1 0.61036 1 0.5112 1 PRSS27 3 (5%) 59 0.2353 1 0.41193 1 0.4676 1 0.51686 1 1 1 0.28503 1 0.037433 0.956 CD320 4 (6%) 58 0.36356 1 0.28237 1 0.15206 1 0.27439 1 1 1 1 1 0.1006 1 SEMA5B 8 (13%) 54 0.77818 1 0.64396 1 0.85218 1 1 1 1 1 0.43805 1 1 1 CCDC150 4 (6%) 58 0.083169 1 0.45607 1 0.03373 0.956 0.105 1 0.35146 1 1 1 0.1006 1 TAF5 4 (6%) 58 0.38151 1 0.59588 1 0.31969 1 0.84366 1 0.35146 1 1 1 0.37433 1 GARS 19 (31%) 43 0.028457 0.956 0.22458 1 0.0087799 0.858 0.0065999 0.858 0.65793 1 1 1 0.64446 1 MUC5B 22 (35%) 40 0.95765 1 0.58097 1 0.73423 1 0.80254 1 0.4122 1 1 1 1 1 KIAA1984 4 (6%) 58 0.86149 1 0.6568 1 0.83323 1 0.51705 1 1 1 0.12354 1 0.5112 1 SRPX 3 (5%) 59 0.92807 1 0.92157 1 0.83262 1 0.62417 1 0.27516 1 0.54627 1 0.5112 1 TNIP2 5 (8%) 57 0.5546 1 0.60496 1 0.086469 1 0.6406 1 0.046264 0.956 1 1 1 1 IDUA 8 (13%) 54 0.14478 1 0.20374 1 0.10867 1 0.23186 1 1 1 1 1 1 1 RNF39 5 (8%) 57 0.73818 1 0.77602 1 0.3217 1 0.84042 1 0.35146 1 1 1 0.37433 1 PABPC1 4 (6%) 58 0.64568 1 0.39774 1 1 1 1 1 0.35146 1 0.61036 1 0.5585 1 SCRT1 3 (5%) 59 0.035691 0.956 0.22462 1 0.83411 1 0.33197 1 0.27516 1 0.54627 1 1 1 MAP1S 5 (8%) 57 0.68784 1 0.40058 1 0.38814 1 1 1 0.42095 1 0.3366 1 1 1 NF1 7 (11%) 55 0.29662 1 0.68057 1 1 1 1 1 1 1 0.0064154 0.858 0.5112 1 AKAP2 4 (6%) 58 0.72992 1 0.58598 1 0.31995 1 0.73719 1 1 1 0.12354 1 NA NA NOTCH2 5 (8%) 57 0.47391 1 0.76613 1 0.68585 1 0.46461 1 0.35146 1 1 1 1 1 FANK1 4 (6%) 58 0.6957 1 0.2177 1 0.062029 1 0.085309 1 0.35146 1 0.28736 1 0.5585 1 NEFH 6 (10%) 56 0.2104 1 0.53569 1 1 1 0.36908 1 0.48412 1 1 1 0.18007 1 NPTX1 3 (5%) 59 0.97891 1 0.89555 1 0.2452 1 0.24373 1 1 1 0.28503 1 1 1 KBTBD13 9 (15%) 53 0.42712 1 0.49667 1 0.088339 1 0.11241 1 0.21798 1 0.14043 1 1 1 RASIP1 6 (10%) 56 0.10614 1 0.9905 1 0.63793 1 0.47853 1 0.48412 1 0.40908 1 1 1 AR 4 (6%) 58 0.14088 1 0.78536 1 0.31882 1 0.15512 1 0.35146 1 1 1 1 1 KNDC1 9 (15%) 53 0.16909 1 0.91244 1 0.12941 1 0.068049 1 1 1 0.14043 1 1 1 SEZ6L2 8 (13%) 54 0.5771 1 0.88309 1 0.85094 1 0.61521 1 1 1 1 1 0.30578 1 VARS 6 (10%) 56 0.96702 1 0.83955 1 0.316 1 0.23291 1 1 1 0.1736 1 0.021132 0.956 IER5 3 (5%) 59 0.0002106 0.0877 0.58814 1 0.087979 1 0.0336 0.956 0.27516 1 0.54627 1 1 1 NMU 5 (8%) 57 0.44952 1 0.27167 1 1 1 0.89578 1 0.42095 1 0.15097 1 0.5112 1 TMEM189 3 (5%) 59 0.20729 1 0.44055 1 NA NA NA NA 1 1 1 1 0.37433 1 ADAD2 4 (6%) 58 0.98511 1 0.62602 1 0.83603 1 1 1 1 1 0.12354 1 1 1 PLEC 13 (21%) 49 0.7837 1 0.56806 1 0.81992 1 0.79431 1 1 1 0.11215 1 0.64446 1 RGMB 6 (10%) 56 0.8231 1 0.72979 1 1 1 0.70679 1 0.48412 1 1 1 0.30578 1 CLIC6 5 (8%) 57 0.33841 1 0.34515 1 0.4718 1 0.70731 1 1 1 0.64731 1 1 1 ZNF814 3 (5%) 59 0.19646 1 0.74276 1 0.02565 0.956 0.063639 1 1 1 1 1 1 1 DSPP 9 (15%) 53 0.93311 1 0.4124 1 0.69067 1 1 1 0.21798 1 0.47135 1 1 1 AMDHD1 10 (16%) 52 0.54724 1 0.043373 0.956 0.8248 1 1 1 0.57771 1 0.3066 1 0.5112 1 CRIPAK 10 (16%) 52 0.6481 1 0.11639 1 0.096309 1 0.3254 1 0.57679 1 1 1 1 1 NOM1 6 (10%) 56 0.92327 1 0.62532 1 0.20846 1 0.2585 1 1 1 1 1 1 1 MAP7 3 (5%) 59 0.94733 1 0.73039 1 1 1 1 1 1 1 1 1 1 1 PTX4 3 (5%) 59 0.00015094 0.0877 0.30122 1 0.01027 0.858 0.03407 0.956 1 1 1 1 1 1 LRP11 6 (10%) 56 0.64893 1 0.49721 1 0.75392 1 1 1 1 1 0.65659 1 0.5585 1 PDCD6 3 (5%) 59 0.92924 1 0.087891 1 0.0103 0.858 0.00482 0.858 0.27516 1 1 1 0.20588 1 SHOX2 3 (5%) 59 0.22377 1 0.89555 1 1 1 0.78365 1 0.27516 1 1 1 1 1 UQCRFS1 5 (8%) 57 0.1994 1 0.049335 0.956 0.03607 0.956 0.02066 0.956 0.42095 1 1 1 0.18007 1 CTBP2 3 (5%) 59 0.91836 1 0.24398 1 0.38829 1 0.16001 1 1 1 1 1 0.5112 1 PRKAR1A 6 (10%) 56 0.78416 1 0.83025 1 0.060779 1 0.062439 1 0.48412 1 0.080787 1 0.37433 1 JMJD4 3 (5%) 59 0.8576 1 0.84389 1 1 1 0.62578 1 1 1 0.28503 1 0.37433 1 HSD17B1 4 (6%) 58 0.62374 1 0.59588 1 0.18562 1 0.22942 1 1 1 1 1 0.37433 1 COQ2 5 (8%) 57 0.8841 1 0.12382 1 0.47033 1 0.70533 1 1 1 0.64731 1 1 1 FEZ2 3 (5%) 59 0.74332 1 0.49069 1 0.8328 1 0.78447 1 0.27516 1 1 1 1 1 DLEU7 3 (5%) 59 0.39796 1 0.61096 1 0.83427 1 1 1 1 1 1 1 1 1 RNF135 3 (5%) 59 0.22377 1 0.83107 1 0.57591 1 0.78417 1 1 1 1 1 0.5112 1 SPIRE2 3 (5%) 59 0.94549 1 0.063693 1 0.38832 1 0.16024 1 1 1 0.54627 1 0.20588 1 KRTAP5-5 3 (5%) 59 0.3242 1 0.066076 1 0.83277 1 1 1 1 1 0.28503 1 1 1 SGK223 3 (5%) 59 0.73709 1 0.46024 1 0.46898 1 0.51695 1 1 1 0.54627 1 0.37433 1 C9ORF66 5 (8%) 57 0.2333 1 0.35852 1 0.42625 1 0.56108 1 1 1 0.3366 1 0.037433 0.956 AQP7 3 (5%) 59 0.73709 1 0.043548 0.956 0.57413 1 0.78372 1 1 1 1 1 1 1 ADAMTS7 4 (6%) 58 0.16884 1 0.12868 1 0.23049 1 0.3851 1 1 1 1 1 1 1 PCDHB13 5 (8%) 57 0.6957 1 0.12701 1 0.34736 1 0.20634 1 1 1 1 1 0.1006 1 CSGALNACT2 3 (5%) 59 0.8655 1 0.70586 1 0.8314 1 1 1 1 1 0.54627 1 1 1 HLA-A 3 (5%) 59 0.32064 1 0.22462 1 1 1 0.62525 1 1 1 0.28503 1 0.20588 1 MTFMT 3 (5%) 59 0.89342 1 0.57689 1 0.83344 1 1 1 1 1 0.040719 0.956 1 1 NLRP5 4 (6%) 58 0.97047 1 0.052989 0.981 0.47793 1 0.1892 1 1 1 1 1 1 1 KCNJ11 4 (6%) 58 0.48486 1 0.41393 1 0.03458 0.956 0.73601 1 0.046264 0.956 0.61036 1 1 1