Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.041 0.145 0.419 52.0 -9999.0 0.0 52.0 KIRREL -0.053 0.188 -9999.0 0.0 -0.579 46.0 46.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.041 0.146 -9999.0 0.0 -0.42 52.0 52.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.007 0.103 -9999.0 0.0 -0.278 46.0 46.0 FYN -0.029 0.121 -9999.0 0.0 -0.322 47.0 47.0 mol:Ca2+ -0.048 0.114 -9999.0 0.0 -0.327 46.0 46.0 mol:DAG -0.049 0.115 -9999.0 0.0 -0.328 46.0 46.0 NPHS2 -0.023 0.11 -9999.0 0.0 -0.515 19.0 19.0 mol:IP3 -0.049 0.115 -9999.0 0.0 -0.328 46.0 46.0 regulation of endocytosis -0.018 0.114 -9999.0 0.0 -0.298 46.0 46.0 Nephrin/NEPH1/podocin/Cholesterol -0.04 0.124 -9999.0 0.0 -0.311 66.0 66.0 establishment of cell polarity -0.041 0.145 -9999.0 0.0 -0.419 52.0 52.0 Nephrin/NEPH1/podocin/NCK1-2 -0.013 0.116 -9999.0 0.0 -0.46 7.0 7.0 Nephrin/NEPH1/beta Arrestin2 -0.017 0.116 -9999.0 0.0 -0.301 46.0 46.0 NPHS1 -0.008 0.064 -9999.0 0.0 -0.498 6.0 6.0 Nephrin/NEPH1/podocin -0.029 0.121 -9999.0 0.0 -0.324 47.0 47.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.044 0.118 -9999.0 0.0 -0.33 46.0 46.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.025 0.121 -9999.0 0.0 -0.314 47.0 47.0 cytoskeleton organization -0.007 0.12 -9999.0 0.0 -0.343 25.0 25.0 Nephrin/NEPH1 -0.027 0.104 -9999.0 0.0 -0.297 52.0 52.0 Nephrin/NEPH1/ZO-1 -0.042 0.109 -9999.0 0.0 -0.331 49.0 49.0